Drosophila melanogaster

35 known processes

DNApol-alpha50 (Dmel_CG7108)

DNA polymerase alpha 50kD

(Aliases: DNApolalpha,anon-WO0140519.257,Dmpol alpha,polalpha50,DNApol-alpha,DNA polalpha,PRI1,Pol,Dmel\CG7108,POLA,CG7108,DNApolalpha50,polalpha,pol alpha,Dpri50,Polalpha)

DNApol-alpha50 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication GO:0006260 48 0.318
chromosome organization GO:0051276 360 0.313
regulation of cell cycle GO:0051726 291 0.292
sister chromatid segregation GO:0000819 92 0.194
regulation of cell cycle phase transition GO:1901987 130 0.172
protein dna complex subunit organization GO:0071824 86 0.115
chromosome segregation GO:0007059 157 0.114
negative regulation of transcription dna templated GO:0045892 237 0.104
negative regulation of gene expression GO:0010629 387 0.090
regulation of cellular catabolic process GO:0031329 157 0.090
mitotic sister chromatid separation GO:0051306 30 0.087
dna recombination GO:0006310 32 0.087
mitotic sister chromatid segregation GO:0000070 87 0.086
dna dependent dna replication GO:0006261 17 0.085
nuclear division GO:0000280 332 0.082
macromolecule catabolic process GO:0009057 161 0.078
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.077
rna catabolic process GO:0006401 37 0.071
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.071
cellular macromolecule catabolic process GO:0044265 136 0.067
regulation of mitotic cell cycle phase transition GO:1901990 130 0.067
double strand break repair GO:0006302 26 0.066
cellular catabolic process GO:0044248 372 0.062
regulation of mitotic cell cycle GO:0007346 190 0.062
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.061
regulation of cell division GO:0051302 72 0.061
protein dna complex assembly GO:0065004 63 0.059
mitotic nuclear division GO:0007067 213 0.058
aging GO:0007568 143 0.058
negative regulation of cellular metabolic process GO:0031324 382 0.057
negative regulation of mitotic cell cycle GO:0045930 109 0.055
proteolysis GO:0006508 192 0.055
positive regulation of macromolecule metabolic process GO:0010604 405 0.055
positive regulation of cellular biosynthetic process GO:0031328 316 0.053
regulation of mitosis GO:0007088 56 0.053
cellular macromolecular complex assembly GO:0034622 153 0.053
programmed cell death GO:0012501 257 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.051
organic substance catabolic process GO:1901575 308 0.048
single organism biosynthetic process GO:0044711 206 0.047
double strand break repair via homologous recombination GO:0000724 13 0.045
regulation of cell cycle process GO:0010564 181 0.044
cellular response to dna damage stimulus GO:0006974 223 0.044
negative regulation of cellular biosynthetic process GO:0031327 277 0.043
catabolic process GO:0009056 409 0.043
organelle fission GO:0048285 340 0.042
organonitrogen compound metabolic process GO:1901564 318 0.041
mitotic cell cycle phase transition GO:0044772 138 0.040
antimicrobial humoral response GO:0019730 99 0.040
regulation of proteolysis GO:0030162 87 0.040
regulation of gene expression epigenetic GO:0040029 128 0.039
body morphogenesis GO:0010171 2 0.039
negative regulation of biosynthetic process GO:0009890 277 0.039
nuclear dna replication GO:0033260 1 0.038
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.038
cell cycle checkpoint GO:0000075 95 0.038
negative regulation of nucleic acid templated transcription GO:1903507 240 0.038
growth GO:0040007 359 0.037
organic cyclic compound catabolic process GO:1901361 168 0.037
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.036
cell death GO:0008219 279 0.035
negative regulation of rna metabolic process GO:0051253 251 0.035
protein catabolic process GO:0030163 101 0.035
modification dependent protein catabolic process GO:0019941 78 0.034
regulation of anatomical structure morphogenesis GO:0022603 242 0.034
regulation of chromosome organization GO:0033044 64 0.033
protein modification process GO:0036211 438 0.033
negative regulation of cell cycle process GO:0010948 109 0.032
macromolecular complex assembly GO:0065003 256 0.032
death GO:0016265 284 0.032
positive regulation of cell cycle process GO:0090068 28 0.031
eye morphogenesis GO:0048592 260 0.031
dna replication initiation GO:0006270 6 0.031
negative regulation of rna biosynthetic process GO:1902679 240 0.031
modification dependent macromolecule catabolic process GO:0043632 79 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.030
regulation of organelle organization GO:0033043 196 0.029
response to organophosphorus GO:0046683 2 0.029
cellular protein complex assembly GO:0043623 71 0.029
response to biotic stimulus GO:0009607 294 0.029
embryonic morphogenesis GO:0048598 206 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.028
mitotic cell cycle checkpoint GO:0007093 88 0.028
humoral immune response GO:0006959 117 0.028
multicellular organismal aging GO:0010259 140 0.028
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.028
regulation of catabolic process GO:0009894 170 0.027
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.027
nucleobase containing compound catabolic process GO:0034655 165 0.026
dna endoreduplication GO:0042023 22 0.026
cellular nitrogen compound catabolic process GO:0044270 165 0.026
ribonucleoside monophosphate catabolic process GO:0009158 39 0.026
regulation of nuclear division GO:0051783 58 0.026
dna metabolic process GO:0006259 227 0.026
aromatic compound catabolic process GO:0019439 166 0.025
proteasomal protein catabolic process GO:0010498 59 0.025
regulation of proteasomal protein catabolic process GO:0061136 39 0.025
chromosome separation GO:0051304 42 0.025
vesicle mediated transport GO:0016192 381 0.025
snrna processing GO:0016180 14 0.024
protein complex assembly GO:0006461 200 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.024
determination of adult lifespan GO:0008340 137 0.023
immune response GO:0006955 246 0.023
apoptotic process GO:0006915 159 0.023
appendage development GO:0048736 401 0.023
cell growth GO:0016049 108 0.023
metaphase plate congression GO:0051310 19 0.023
cell cycle dna replication GO:0044786 23 0.023
positive regulation of catalytic activity GO:0043085 118 0.022
metaphase anaphase transition of cell cycle GO:0044784 28 0.022
regulation of hydrolase activity GO:0051336 97 0.022
organic substance transport GO:0071702 257 0.022
negative regulation of cell cycle phase transition GO:1901988 103 0.022
positive regulation of cell cycle GO:0045787 43 0.021
regulation of programmed cell death GO:0043067 152 0.021
establishment of localization in cell GO:0051649 402 0.021
organic acid metabolic process GO:0006082 103 0.021
cell division GO:0051301 248 0.021
cell cycle phase transition GO:0044770 140 0.021
positive regulation of developmental process GO:0051094 143 0.021
response to wounding GO:0009611 94 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.020
positive regulation of cellular component organization GO:0051130 156 0.020
protein complex biogenesis GO:0070271 201 0.020
regulation of dna templated transcription elongation GO:0032784 17 0.020
ubiquitin dependent protein catabolic process GO:0006511 78 0.020
negative regulation of organelle organization GO:0010639 56 0.019
regulation of chromosome segregation GO:0051983 32 0.019
cellular ketone metabolic process GO:0042180 24 0.019
regulation of catalytic activity GO:0050790 185 0.019
dna damage checkpoint GO:0000077 78 0.019
regulation of protein catabolic process GO:0042176 55 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
regulation of cell death GO:0010941 173 0.019
small molecule metabolic process GO:0044281 305 0.019
snrna 3 end processing GO:0034472 14 0.019
regulation of double strand break repair GO:2000779 3 0.019
response to other organism GO:0051707 293 0.019
developmental growth GO:0048589 280 0.018
regulation of molecular function GO:0065009 217 0.018
ribonucleotide metabolic process GO:0009259 145 0.018
homeostatic process GO:0042592 199 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.018
protein localization GO:0008104 284 0.018
locomotory behavior GO:0007626 176 0.018
polyadenylation dependent ncrna catabolic process GO:0043634 1 0.018
antimicrobial peptide production GO:0002775 46 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
regulation of cell morphogenesis GO:0022604 163 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
rna 3 end processing GO:0031123 45 0.016
regulation of growth GO:0040008 233 0.016
mitotic recombination GO:0006312 2 0.016
cellular protein modification process GO:0006464 438 0.016
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.016
ncrna 3 end processing GO:0043628 17 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
positive regulation of gene expression GO:0010628 290 0.016
ameboidal type cell migration GO:0001667 151 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
regulation of cellular protein catabolic process GO:1903362 44 0.016
positive regulation of hydrolase activity GO:0051345 78 0.016
negative regulation of cell cycle GO:0045786 116 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
imaginal disc derived appendage development GO:0048737 399 0.015
regulation of protein metabolic process GO:0051246 256 0.015
mesoderm development GO:0007498 78 0.015
response to external biotic stimulus GO:0043207 293 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
positive regulation of mitotic cell cycle GO:0045931 34 0.015
cell recognition GO:0008037 102 0.015
cellular protein catabolic process GO:0044257 83 0.015
regulation of cell differentiation GO:0045595 302 0.015
appendage morphogenesis GO:0035107 397 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
mitotic cell cycle embryonic GO:0045448 38 0.015
cellular amine metabolic process GO:0044106 12 0.015
actin filament based process GO:0030029 220 0.015
positive regulation of biosynthetic process GO:0009891 316 0.014
nucleotide metabolic process GO:0009117 161 0.014
cell cycle g1 s phase transition GO:0044843 31 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.014
response to oxygen containing compound GO:1901700 200 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
developmental growth involved in morphogenesis GO:0060560 65 0.014
response to lipopolysaccharide GO:0032496 4 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
formation of anatomical boundary GO:0048859 37 0.014
spinal cord development GO:0021510 1 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
regulation of apoptotic process GO:0042981 130 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
mrna processing GO:0006397 104 0.014
histone modification GO:0016570 106 0.014
mitotic cytokinesis GO:0000281 50 0.014
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
gene silencing GO:0016458 138 0.013
organelle localization GO:0051640 148 0.013
regulation of mitotic sister chromatid separation GO:0010965 28 0.013
phagocytosis GO:0006909 215 0.013
response to abiotic stimulus GO:0009628 341 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
organophosphate catabolic process GO:0046434 112 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
negative regulation of gene expression epigenetic GO:0045814 77 0.013
single organism intracellular transport GO:1902582 207 0.013
mitotic spindle elongation GO:0000022 81 0.013
protein acylation GO:0043543 42 0.013
heterocycle catabolic process GO:0046700 166 0.013
protein localization to organelle GO:0033365 82 0.013
regulation of mitotic sister chromatid segregation GO:0033047 28 0.013
purine containing compound metabolic process GO:0072521 155 0.013
sensory organ morphogenesis GO:0090596 260 0.013
regulation of localization GO:0032879 275 0.013
spindle organization GO:0007051 253 0.013
stem cell differentiation GO:0048863 117 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
response to heat GO:0009408 63 0.012
negative regulation of cell death GO:0060548 81 0.012
protein heterooligomerization GO:0051291 4 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
meiotic chromosome segregation GO:0045132 59 0.012
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.012
production of molecular mediator of immune response GO:0002440 46 0.012
formation of organ boundary GO:0010160 30 0.012
taxis GO:0042330 304 0.012
chromatin silencing GO:0006342 76 0.012
positive regulation of growth GO:0045927 75 0.012
compound eye morphogenesis GO:0001745 249 0.012
response to organic substance GO:0010033 284 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
recombinational repair GO:0000725 13 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
g1 s transition of mitotic cell cycle GO:0000082 31 0.011
regulation of cell cycle g1 s phase transition GO:1902806 23 0.011
regionalization GO:0003002 416 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
single organism cellular localization GO:1902580 180 0.011
cytoplasmic transport GO:0016482 130 0.011
regulation of dna metabolic process GO:0051052 34 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
positive regulation of response to stimulus GO:0048584 323 0.011
actin cytoskeleton organization GO:0030036 206 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
wound healing GO:0042060 75 0.011
mrna metabolic process GO:0016071 124 0.011
cell motility GO:0048870 251 0.011
chromatin remodeling GO:0006338 72 0.011
chromatin modification GO:0016568 147 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
multi organism behavior GO:0051705 175 0.010
tissue migration GO:0090130 155 0.010
amine metabolic process GO:0009308 12 0.010
protein processing GO:0016485 68 0.010
eye development GO:0001654 323 0.010
negative regulation of cellular catabolic process GO:0031330 34 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.010
oxoacid metabolic process GO:0043436 103 0.010
mrna 3 end processing GO:0031124 28 0.010
nucleoside metabolic process GO:0009116 127 0.010
sister chromatid cohesion GO:0007062 18 0.010

DNApol-alpha50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018