Drosophila melanogaster

188 known processes

mts (Dmel_CG7109)

microtubule star

(Aliases: PP2A 28D,MTS/PP2A,PP2A[[C]],PP2Ac,l(2)s5286,PP2a 28D,dPP2A,Mts,PP2A C,l(2)02496,PP2a,Pp2A,PP2,Dmel\CG7109,PP2A,DmPp2A-28D,CG7109,5559,PP2A-C,Pp2A-28D,ER2-6)

mts biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of gene expression GO:0010629 387 0.915
Rat
organelle fission GO:0048285 340 0.784
regulation of cellular protein metabolic process GO:0032268 243 0.782
Human Rat
positive regulation of cellular protein metabolic process GO:0032270 118 0.757
Human Rat
imaginal disc derived appendage development GO:0048737 399 0.735
negative regulation of cellular metabolic process GO:0031324 382 0.691
Rat
regulation of protein metabolic process GO:0051246 256 0.679
Human Rat
regulation of cellular catabolic process GO:0031329 157 0.664
regulation of catabolic process GO:0009894 170 0.655
Rat
regulation of intracellular signal transduction GO:1902531 236 0.563
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.555
Rat
actin filament based process GO:0030029 220 0.527
death GO:0016265 284 0.517
Mouse Rat
determination of adult lifespan GO:0008340 137 0.507
positive regulation of catabolic process GO:0009896 105 0.488
establishment of localization in cell GO:0051649 402 0.475
Rat
homeostatic process GO:0042592 199 0.463
Rat
intracellular transport GO:0046907 228 0.451
Rat
imaginal disc derived appendage morphogenesis GO:0035114 395 0.423
regulation of molecular function GO:0065009 217 0.401
protein modification process GO:0036211 438 0.367
dendrite morphogenesis GO:0048813 199 0.359
asymmetric neuroblast division GO:0055059 33 0.351
spindle organization GO:0007051 253 0.348
single organism intracellular transport GO:1902582 207 0.336
Rat
negative regulation of cellular biosynthetic process GO:0031327 277 0.327
Rat
cellular catabolic process GO:0044248 372 0.327
appendage morphogenesis GO:0035107 397 0.306
cellular homeostasis GO:0019725 80 0.284
Rat
regulation of gene expression epigenetic GO:0040029 128 0.276
cell death GO:0008219 279 0.275
Mouse Rat
ubiquitin dependent protein catabolic process GO:0006511 78 0.271
Mouse
regulation of cell cycle GO:0051726 291 0.270
cell cycle phase transition GO:0044770 140 0.266
imaginal disc derived wing morphogenesis GO:0007476 337 0.263
axonogenesis GO:0007409 290 0.251
endocytosis GO:0006897 310 0.246
compound eye morphogenesis GO:0001745 249 0.245
neuroblast division GO:0055057 35 0.243
mitotic spindle organization GO:0007052 220 0.237
Worm
gene silencing by rna GO:0031047 57 0.237
protein localization GO:0008104 284 0.229
Rat
apoptotic cell clearance GO:0043277 14 0.227
dendrite development GO:0016358 204 0.225
regulation of proteolysis GO:0030162 87 0.219
Rat
regulation of cytoskeleton organization GO:0051493 89 0.212
positive regulation of proteolysis GO:0045862 52 0.207
Rat
regulation of nervous system development GO:0051960 248 0.207
membrane invagination GO:0010324 11 0.203
cellular protein modification process GO:0006464 438 0.202
posttranscriptional gene silencing by rna GO:0035194 45 0.201
gene silencing GO:0016458 138 0.199
cell division GO:0051301 248 0.196
non sensory hair organization GO:0035316 47 0.190
regulation of phosphate metabolic process GO:0019220 210 0.189
Human Rat
positive regulation of molecular function GO:0044093 136 0.180
Human Rat
oocyte microtubule cytoskeleton organization GO:0016325 35 0.178
nuclear division GO:0000280 332 0.173
regulation of hydrolase activity GO:0051336 97 0.173
Rat
tissue morphogenesis GO:0048729 297 0.172
developmental growth GO:0048589 280 0.169
canonical wnt signaling pathway GO:0060070 21 0.167
protein polymerization GO:0051258 42 0.162
vesicle mediated transport GO:0016192 381 0.162
embryonic morphogenesis GO:0048598 206 0.161
meiotic cell cycle GO:0051321 171 0.157
Worm
ras protein signal transduction GO:0007265 88 0.156
Rat
locomotory behavior GO:0007626 176 0.156
proteolysis GO:0006508 192 0.155
Mouse Rat
negative regulation of signal transduction GO:0009968 206 0.154
Rat
imaginal disc derived wing hair site selection GO:0035320 4 0.151
compound eye development GO:0048749 307 0.150
regulation of catalytic activity GO:0050790 185 0.146
positive regulation of cellular component organization GO:0051130 156 0.145
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.145
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.144
Rat
positive regulation of cellular catabolic process GO:0031331 95 0.141
synapse organization GO:0050808 196 0.139
negative regulation of cellular protein metabolic process GO:0032269 85 0.136
Rat
posttranscriptional gene silencing GO:0016441 46 0.133
cellular protein complex assembly GO:0043623 71 0.133
positive regulation of protein metabolic process GO:0051247 128 0.125
Human Rat
positive regulation of phosphate metabolic process GO:0045937 139 0.116
Human Rat
single organism cellular localization GO:1902580 180 0.116
Rat
meiotic spindle organization GO:0000212 36 0.115
Worm
regulation of actin cytoskeleton organization GO:0032956 42 0.111
cellular response to dna damage stimulus GO:0006974 223 0.109
macromolecular complex assembly GO:0065003 256 0.109
central nervous system development GO:0007417 201 0.107
negative regulation of cell communication GO:0010648 223 0.106
Rat
establishment of cell polarity GO:0030010 40 0.105
regulation of protein modification process GO:0031399 112 0.105
Human Rat
intracellular signal transduction GO:0035556 300 0.102
Rat
intracellular protein transport GO:0006886 104 0.101
Rat
regulation of mitotic cell cycle GO:0007346 190 0.100
cortical cytoskeleton organization GO:0030865 29 0.100
regulation of protein catabolic process GO:0042176 55 0.096
Rat
appendage development GO:0048736 401 0.092
regulation of multicellular organismal development GO:2000026 414 0.090
positive regulation of phosphorylation GO:0042327 87 0.090
Human
actin cytoskeleton organization GO:0030036 206 0.089
circulatory system development GO:0072359 82 0.085
Rat
regulation of organelle organization GO:0033043 196 0.085
gland development GO:0048732 191 0.084
guanosine containing compound metabolic process GO:1901068 74 0.084
mapk cascade GO:0000165 107 0.083
post embryonic appendage morphogenesis GO:0035120 385 0.083
immune system development GO:0002520 57 0.083
cellular macromolecule localization GO:0070727 220 0.081
Rat
regulation of phosphorus metabolic process GO:0051174 210 0.081
Human Rat
negative regulation of rna biosynthetic process GO:1902679 240 0.080
Rat
chromosome segregation GO:0007059 157 0.079
neuroblast proliferation GO:0007405 74 0.079
cell motility GO:0048870 251 0.078
regulation of localization GO:0032879 275 0.077
Rat
hair cell differentiation GO:0035315 47 0.076
mitotic cell cycle phase transition GO:0044772 138 0.076
phagocytosis GO:0006909 215 0.074
regulation of purine nucleotide catabolic process GO:0033121 48 0.070
small gtpase mediated signal transduction GO:0007264 88 0.069
Rat
aging GO:0007568 143 0.069
multicellular organismal aging GO:0010259 140 0.067
modification dependent macromolecule catabolic process GO:0043632 79 0.067
Mouse
regulation of dendrite morphogenesis GO:0048814 28 0.065
notch signaling pathway GO:0007219 120 0.065
positive regulation of phosphorus metabolic process GO:0010562 139 0.065
Human Rat
membrane organization GO:0061024 112 0.062
Worm
embryo development ending in birth or egg hatching GO:0009792 152 0.062
Worm
regulation of cell cycle process GO:0010564 181 0.062
neuron recognition GO:0008038 101 0.062
apoptotic process GO:0006915 159 0.061
Mouse Rat
gtp metabolic process GO:0046039 72 0.059
response to extracellular stimulus GO:0009991 116 0.059
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.058
regulation of protein polymerization GO:0032271 28 0.058
chromosome organization GO:0051276 360 0.057
regulation of phosphatase activity GO:0010921 3 0.056
Rat
modification dependent protein catabolic process GO:0019941 78 0.056
Mouse
proteasomal protein catabolic process GO:0010498 59 0.056
Mouse
positive regulation of developmental process GO:0051094 143 0.055
Worm
establishment of planar polarity GO:0001736 87 0.055
cellular response to extracellular stimulus GO:0031668 64 0.055
protein complex assembly GO:0006461 200 0.054
salivary gland morphogenesis GO:0007435 145 0.053
axon development GO:0061564 297 0.053
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.053
establishment or maintenance of cell polarity GO:0007163 167 0.053
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.052
cellular macromolecular complex assembly GO:0034622 153 0.051
dorsal ventral pattern formation GO:0009953 133 0.051
regulation of anatomical structure morphogenesis GO:0022603 242 0.051
regulation of actin filament length GO:0030832 27 0.050
regulation of actin polymerization or depolymerization GO:0008064 27 0.050
positive regulation of cell communication GO:0010647 250 0.050
positive regulation of response to stimulus GO:0048584 323 0.049
cellular response to organic substance GO:0071310 132 0.049
Rat
pole plasm assembly GO:0007315 61 0.048
autophagic vacuole assembly GO:0000045 2 0.047
protein maturation GO:0051604 71 0.047
positive regulation of cell proliferation GO:0008284 47 0.046
protein k48 linked ubiquitination GO:0070936 3 0.045
enzyme linked receptor protein signaling pathway GO:0007167 179 0.043
actin polymerization or depolymerization GO:0008154 31 0.043
cellular protein localization GO:0034613 160 0.043
Rat
regulation of gtpase activity GO:0043087 44 0.043
digestive system development GO:0055123 149 0.043
wing disc morphogenesis GO:0007472 344 0.043
notch receptor processing GO:0007220 13 0.042
regulation of endopeptidase activity GO:0052548 36 0.042
Rat
lipid localization GO:0010876 54 0.042
phagocytosis engulfment GO:0006911 11 0.041
single organism behavior GO:0044708 391 0.041
asymmetric stem cell division GO:0098722 49 0.041
germarium derived female germ line cyst formation GO:0030727 42 0.041
cell proliferation GO:0008283 299 0.040
regulation of notch signaling pathway GO:0008593 100 0.040
regulation of cellular protein catabolic process GO:1903362 44 0.038
regulation of cell development GO:0060284 215 0.037
catabolic process GO:0009056 409 0.037
dephosphorylation GO:0016311 51 0.037
morphogenesis of a polarized epithelium GO:0001738 93 0.036
actin filament organization GO:0007015 126 0.036
epidermis development GO:0008544 65 0.036
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.035
trna modification GO:0006400 2 0.034
organophosphate biosynthetic process GO:0090407 46 0.034
cellular response to endogenous stimulus GO:0071495 80 0.034
Rat
exocrine system development GO:0035272 162 0.034
regulation of mitotic cell cycle phase transition GO:1901990 130 0.033
establishment of monopolar cell polarity GO:0061162 15 0.033
synapse assembly GO:0007416 143 0.033
positive regulation of protein polymerization GO:0032273 14 0.033
negative regulation of protein metabolic process GO:0051248 85 0.033
Rat
regulation of microtubule based process GO:0032886 49 0.032
rhythmic process GO:0048511 106 0.032
establishment of mitotic spindle localization GO:0040001 17 0.032
organophosphate catabolic process GO:0046434 112 0.031
regulation of gene silencing GO:0060968 63 0.031
posttranscriptional regulation of gene expression GO:0010608 145 0.031
glycosyl compound metabolic process GO:1901657 127 0.030
negative regulation of catalytic activity GO:0043086 42 0.030
head development GO:0060322 135 0.030
meiotic nuclear division GO:0007126 151 0.030
negative regulation of molecular function GO:0044092 51 0.030
Rat
regulation of cell differentiation GO:0045595 302 0.029
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.029
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.029
chemotaxis GO:0006935 249 0.029
regulation of meiosis GO:0040020 3 0.028
ribonucleotide catabolic process GO:0009261 109 0.028
positive regulation of apoptotic signaling pathway GO:2001235 4 0.028
brain development GO:0007420 120 0.028
generation of precursor metabolites and energy GO:0006091 42 0.028
immune system process GO:0002376 347 0.028
establishment of proximal distal cell polarity GO:0022606 4 0.028
stem cell proliferation GO:0072089 88 0.027
anterior posterior axis specification embryo GO:0008595 103 0.027
cortical actin cytoskeleton organization GO:0030866 24 0.027
cellular response to organonitrogen compound GO:0071417 36 0.027
Rat
regulation of ras protein signal transduction GO:0046578 93 0.027
Rat
regulation of protein phosphorylation GO:0001932 64 0.026
Human Rat
positive regulation of gene expression GO:0010628 290 0.025
dna damage checkpoint GO:0000077 78 0.025
axon guidance GO:0007411 233 0.025
oocyte development GO:0048599 124 0.025
anterior posterior pattern specification GO:0009952 136 0.025
regulation of microtubule cytoskeleton organization GO:0070507 41 0.025
regulation of protein complex assembly GO:0043254 42 0.024
tissue death GO:0016271 102 0.024
regulation of endocytosis GO:0030100 37 0.024
establishment of organelle localization GO:0051656 122 0.024
taxis GO:0042330 304 0.023
neuron projection guidance GO:0097485 241 0.023
eye development GO:0001654 323 0.023
establishment of spindle orientation GO:0051294 18 0.023
regulation of cell shape GO:0008360 113 0.023
nucleotide metabolic process GO:0009117 161 0.023
purine containing compound metabolic process GO:0072521 155 0.023
gland morphogenesis GO:0022612 145 0.023
long term memory GO:0007616 62 0.022
microtubule based movement GO:0007018 51 0.022
macromolecule catabolic process GO:0009057 161 0.022
Mouse Rat
regulation of anatomical structure size GO:0090066 163 0.022
muscle structure development GO:0061061 224 0.022
mitotic nuclear division GO:0007067 213 0.022
regulation of cell cycle phase transition GO:1901987 130 0.022
regulation of actin filament polymerization GO:0030833 25 0.022
morphogenesis of embryonic epithelium GO:0016331 94 0.022
oocyte axis specification GO:0007309 108 0.021
regulation of proteasomal protein catabolic process GO:0061136 39 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
Rat
programmed cell death GO:0012501 257 0.021
Mouse Rat
positive regulation of cell migration GO:0030335 2 0.021
organophosphate metabolic process GO:0019637 195 0.021
imaginal disc derived wing hair organization GO:0035317 45 0.020
establishment of mitotic spindle orientation GO:0000132 13 0.020
macromolecular complex disassembly GO:0032984 37 0.020
Worm
negative regulation of proteolysis GO:0045861 31 0.020
regulation of cell division GO:0051302 72 0.020
regulation of gtp catabolic process GO:0033124 44 0.020
mitotic cell cycle embryonic GO:0045448 38 0.019
positive regulation of organelle organization GO:0010638 65 0.019
gtp catabolic process GO:0006184 72 0.019
response to other organism GO:0051707 293 0.019
purine containing compound catabolic process GO:0072523 112 0.019
phosphorylation GO:0016310 294 0.019
Human Rat
regulation of cellular component biogenesis GO:0044087 201 0.019
hematopoietic or lymphoid organ development GO:0048534 57 0.019
regulation of purine nucleotide metabolic process GO:1900542 62 0.019
localization of cell GO:0051674 257 0.019
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
Rat
establishment of spindle localization GO:0051293 22 0.018
regionalization GO:0003002 416 0.018
attachment of spindle microtubules to kinetochore GO:0008608 5 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.018
Mouse
positive regulation of cell differentiation GO:0045597 64 0.018
protein catabolic process GO:0030163 101 0.018
Mouse Rat
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
response to nutrient levels GO:0031667 114 0.017
negative regulation of phosphorus metabolic process GO:0010563 45 0.017
Rat
imaginal disc growth GO:0007446 37 0.017
actin filament polymerization GO:0030041 27 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
regulation of cell death GO:0010941 173 0.017
Rat
regulation of protein serine threonine kinase activity GO:0071900 25 0.017
Human
protein processing GO:0016485 68 0.016
regulation of transport GO:0051049 181 0.016
Rat
response to organic substance GO:0010033 284 0.016
Rat
regulation of nuclear division GO:0051783 58 0.016
skeletal muscle organ development GO:0060538 48 0.016
somatic stem cell division GO:0048103 37 0.016
hemocyte differentiation GO:0042386 38 0.016
neuromuscular process GO:0050905 21 0.016
regulation of mapk cascade GO:0043408 92 0.016
regulation of mitotic sister chromatid segregation GO:0033047 28 0.016
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.015
rna interference GO:0016246 27 0.015
positive regulation of programmed cell death GO:0043068 62 0.015
Rat
regulation of organ morphogenesis GO:2000027 78 0.015
germ line cyst formation GO:0048134 44 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
Mouse
muscle organ development GO:0007517 127 0.015
regulation of synapse structure and activity GO:0050803 128 0.015
mrna 3 end processing GO:0031124 28 0.015
regulation of system process GO:0044057 36 0.015
regulation of cell proliferation GO:0042127 163 0.015
microtubule organizing center organization GO:0031023 168 0.014
single organism catabolic process GO:0044712 228 0.014
single organism carbohydrate metabolic process GO:0044723 72 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
compound eye retinal cell programmed cell death GO:0046667 23 0.014
cytoplasmic transport GO:0016482 130 0.014
Rat
regulation of response to stress GO:0080134 200 0.014
locomotor rhythm GO:0045475 56 0.014
cellular chemical homeostasis GO:0055082 40 0.013
Rat
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.013
encapsulation of foreign target GO:0035010 38 0.013
cellular carbohydrate metabolic process GO:0044262 22 0.013
regulation of protein dephosphorylation GO:0035304 5 0.013
Rat
female germ line cyst formation GO:0048135 42 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
Rat
regulation of embryonic development GO:0045995 68 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
developmental programmed cell death GO:0010623 138 0.013
regulation of protein deacetylation GO:0090311 2 0.013
regulation of cell projection assembly GO:0060491 30 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
cellular metal ion homeostasis GO:0006875 31 0.012
regulation of neuroblast proliferation GO:1902692 34 0.012
salivary gland development GO:0007431 162 0.012
heterocycle catabolic process GO:0046700 166 0.012
blastoderm segmentation GO:0007350 159 0.012
positive regulation of cell motility GO:2000147 3 0.012
cellular protein catabolic process GO:0044257 83 0.012
Mouse
engulfment of apoptotic cell GO:0043652 6 0.012
regulation of protein export from nucleus GO:0046825 3 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
Human Rat
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
Human Rat
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
erk1 and erk2 cascade GO:0070371 39 0.012
regulation of nucleotide metabolic process GO:0006140 62 0.012
stem cell division GO:0017145 69 0.012
regulation of intracellular transport GO:0032386 64 0.012
Rat
regulation of actin filament based process GO:0032970 42 0.012
developmental maturation GO:0021700 172 0.012
negative regulation of neurogenesis GO:0050768 53 0.011
guanosine containing compound catabolic process GO:1901069 74 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
Rat
detection of abiotic stimulus GO:0009582 66 0.011
embryonic axis specification GO:0000578 107 0.011
regulation of transferase activity GO:0051338 58 0.011
Human
positive regulation of cell development GO:0010720 61 0.011
positive regulation of signal transduction GO:0009967 223 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
Rat
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.011
vacuole organization GO:0007033 8 0.011
regulation of cellular localization GO:0060341 136 0.011
Rat
pole plasm oskar mrna localization GO:0045451 46 0.011
autophagy GO:0006914 108 0.011
skin development GO:0043588 65 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.011
wnt signaling pathway GO:0016055 98 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
Rat
organelle localization GO:0051640 148 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
photoreceptor cell development GO:0042461 96 0.010
negative regulation of imaginal disc growth GO:0045571 8 0.010
oocyte anterior posterior axis specification GO:0007314 72 0.010
organic substance catabolic process GO:1901575 308 0.010
Mouse Rat
defense response GO:0006952 300 0.010
synaptic growth at neuromuscular junction GO:0051124 119 0.010
positive regulation of neurogenesis GO:0050769 41 0.010
nucleocytoplasmic transport GO:0006913 72 0.010
Rat

mts disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012