Drosophila melanogaster

138 known processes

Not1 (Dmel_CG34407)

CG34407 gene product from transcript CG34407-RC

(Aliases: anon-WO0118547.221,NOT1,Dmel_CG1884,anon-EST:Liang-1.29,Dmel_CG1874,clone 1.29,CG34407,CG1874,NOT,not1,CG1884,Dmel\CG34407)

Not1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.167
post embryonic appendage morphogenesis GO:0035120 385 0.154
wing disc morphogenesis GO:0007472 344 0.091
appendage morphogenesis GO:0035107 397 0.084
appendage development GO:0048736 401 0.079
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.078
cellular macromolecule localization GO:0070727 220 0.075
rna processing GO:0006396 147 0.069
erbb signaling pathway GO:0038127 58 0.069
imaginal disc derived appendage development GO:0048737 399 0.068
organic substance catabolic process GO:1901575 308 0.065
positive regulation of rna metabolic process GO:0051254 271 0.065
mitotic cell cycle phase transition GO:0044772 138 0.064
positive regulation of gene expression GO:0010628 290 0.064
negative regulation of gene expression GO:0010629 387 0.058
transcription from rna polymerase ii promoter GO:0006366 368 0.057
cell death GO:0008219 279 0.057
macromolecule catabolic process GO:0009057 161 0.057
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.057
regulation of localization GO:0032879 275 0.056
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.055
cellular nitrogen compound catabolic process GO:0044270 165 0.053
regionalization GO:0003002 416 0.053
cellular macromolecule catabolic process GO:0044265 136 0.053
imaginal disc derived wing morphogenesis GO:0007476 337 0.052
neurological system process GO:0050877 358 0.051
establishment of localization in cell GO:0051649 402 0.051
phosphorylation GO:0016310 294 0.050
peptidyl amino acid modification GO:0018193 105 0.050
regulation of erbb signaling pathway GO:1901184 42 0.050
enzyme linked receptor protein signaling pathway GO:0007167 179 0.049
chromosome organization GO:0051276 360 0.049
regulation of cellular protein metabolic process GO:0032268 243 0.049
morphogenesis of an epithelium GO:0002009 276 0.049
catabolic process GO:0009056 409 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.047
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.047
regulation of cellular ketone metabolic process GO:0010565 3 0.047
positive regulation of transcription dna templated GO:0045893 266 0.047
response to abiotic stimulus GO:0009628 341 0.047
cellular protein modification process GO:0006464 438 0.046
gland development GO:0048732 191 0.046
positive regulation of response to stimulus GO:0048584 323 0.046
cellular ketone metabolic process GO:0042180 24 0.045
vesicle mediated transport GO:0016192 381 0.043
negative regulation of cell communication GO:0010648 223 0.043
single organism behavior GO:0044708 391 0.043
response to other organism GO:0051707 293 0.043
protein modification process GO:0036211 438 0.042
response to organic substance GO:0010033 284 0.042
negative regulation of erbb signaling pathway GO:1901185 29 0.041
eye photoreceptor cell differentiation GO:0001754 145 0.041
cell proliferation GO:0008283 299 0.041
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
epidermal growth factor receptor signaling pathway GO:0007173 58 0.040
regulation of immune system process GO:0002682 176 0.040
eye development GO:0001654 323 0.040
immune response GO:0006955 246 0.040
positive regulation of cell communication GO:0010647 250 0.039
cell motility GO:0048870 251 0.039
amine metabolic process GO:0009308 12 0.039
response to external biotic stimulus GO:0043207 293 0.038
dendrite development GO:0016358 204 0.038
nucleobase containing compound catabolic process GO:0034655 165 0.038
defense response to other organism GO:0098542 225 0.038
programmed cell death GO:0012501 257 0.037
cellular amino acid metabolic process GO:0006520 61 0.037
negative regulation of signal transduction GO:0009968 206 0.037
negative regulation of transcription dna templated GO:0045892 237 0.037
regulation of cellular amine metabolic process GO:0033238 3 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.036
organonitrogen compound metabolic process GO:1901564 318 0.036
sensory organ morphogenesis GO:0090596 260 0.035
negative regulation of cellular metabolic process GO:0031324 382 0.035
tissue morphogenesis GO:0048729 297 0.035
adult behavior GO:0030534 137 0.034
compound eye morphogenesis GO:0001745 249 0.034
growth GO:0040007 359 0.034
open tracheal system development GO:0007424 204 0.033
organelle assembly GO:0070925 198 0.033
posttranscriptional regulation of gene expression GO:0010608 145 0.032
death GO:0016265 284 0.032
regulation of protein metabolic process GO:0051246 256 0.032
protein phosphorylation GO:0006468 169 0.031
compound eye development GO:0048749 307 0.031
single organism cellular localization GO:1902580 180 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.031
intracellular signal transduction GO:0035556 300 0.031
photoreceptor cell differentiation GO:0046530 170 0.031
mrna metabolic process GO:0016071 124 0.031
positive regulation of signal transduction GO:0009967 223 0.031
tube morphogenesis GO:0035239 191 0.031
positive regulation of rna biosynthetic process GO:1902680 266 0.031
exocrine system development GO:0035272 162 0.031
localization of cell GO:0051674 257 0.031
salivary gland development GO:0007431 162 0.031
epithelial cell differentiation GO:0030855 322 0.031
positive regulation of biosynthetic process GO:0009891 316 0.030
negative regulation of cellular biosynthetic process GO:0031327 277 0.030
cellular response to chemical stimulus GO:0070887 199 0.030
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.030
immune system process GO:0002376 347 0.029
cellular amine metabolic process GO:0044106 12 0.029
defense response GO:0006952 300 0.029
positive regulation of signaling GO:0023056 243 0.029
regulation of molecular function GO:0065009 217 0.029
gland morphogenesis GO:0022612 145 0.028
regulation of organelle organization GO:0033043 196 0.028
endocytosis GO:0006897 310 0.028
organic acid metabolic process GO:0006082 103 0.028
oxoacid metabolic process GO:0043436 103 0.028
defense response to bacterium GO:0042742 178 0.028
organic substance transport GO:0071702 257 0.028
phagocytosis GO:0006909 215 0.028
regulation of phosphorus metabolic process GO:0051174 210 0.027
eye morphogenesis GO:0048592 260 0.027
segmentation GO:0035282 207 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
spindle organization GO:0007051 253 0.026
positive regulation of nucleic acid templated transcription GO:1903508 266 0.026
histolysis GO:0007559 102 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.025
single organism intracellular transport GO:1902582 207 0.025
cell cycle checkpoint GO:0000075 95 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
intracellular transport GO:0046907 228 0.025
embryo development ending in birth or egg hatching GO:0009792 152 0.025
cognition GO:0050890 141 0.024
cell division GO:0051301 248 0.024
regulation of immune response GO:0050776 118 0.024
regulation of cellular localization GO:0060341 136 0.023
negative regulation of signaling GO:0023057 219 0.023
regulation of transport GO:0051049 181 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
mrna processing GO:0006397 104 0.023
forebrain development GO:0030900 2 0.023
cellular response to dna damage stimulus GO:0006974 223 0.023
regulation of response to stress GO:0080134 200 0.023
developmental growth GO:0048589 280 0.022
dendrite morphogenesis GO:0048813 199 0.022
negative regulation of biosynthetic process GO:0009890 277 0.022
regulation of cell cycle GO:0051726 291 0.022
response to biotic stimulus GO:0009607 294 0.022
cellular component assembly involved in morphogenesis GO:0010927 151 0.022
mrna catabolic process GO:0006402 33 0.022
locomotory behavior GO:0007626 176 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
negative regulation of cell cycle process GO:0010948 109 0.022
tube development GO:0035295 244 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
regulation of mitotic cell cycle phase transition GO:1901990 130 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
regulation of cell cycle phase transition GO:1901987 130 0.021
aromatic compound catabolic process GO:0019439 166 0.021
salivary gland morphogenesis GO:0007435 145 0.021
regulation of innate immune response GO:0045088 71 0.021
defense response to gram negative bacterium GO:0050829 94 0.021
cell cycle phase transition GO:0044770 140 0.021
small molecule metabolic process GO:0044281 305 0.021
multicellular organismal aging GO:0010259 140 0.021
positive regulation of immune response GO:0050778 63 0.021
imaginal disc derived wing vein specification GO:0007474 48 0.021
regulation of phosphate metabolic process GO:0019220 210 0.020
endomembrane system organization GO:0010256 119 0.020
regulation of mrna processing GO:0050684 71 0.020
negative regulation of cell cycle GO:0045786 116 0.020
protein complex biogenesis GO:0070271 201 0.020
developmental programmed cell death GO:0010623 138 0.020
establishment or maintenance of cell polarity GO:0007163 167 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
muscle structure development GO:0061061 224 0.020
cell migration GO:0016477 238 0.020
embryonic development via the syncytial blastoderm GO:0001700 148 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
establishment of protein localization GO:0045184 163 0.019
learning or memory GO:0007611 141 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
ovarian follicle cell development GO:0030707 248 0.019
chromatin modification GO:0016568 147 0.019
golgi organization GO:0007030 66 0.019
cellular protein localization GO:0034613 160 0.019
dna damage checkpoint GO:0000077 78 0.019
modification dependent macromolecule catabolic process GO:0043632 79 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
proteolysis GO:0006508 192 0.019
negative regulation of rna metabolic process GO:0051253 251 0.018
regulation of protein modification process GO:0031399 112 0.018
compound eye photoreceptor cell differentiation GO:0001751 140 0.018
regulation of cell death GO:0010941 173 0.018
positive regulation of defense response GO:0031349 59 0.018
innate immune response GO:0045087 144 0.018
homeostatic process GO:0042592 199 0.018
body morphogenesis GO:0010171 2 0.018
negative regulation of cell cycle phase transition GO:1901988 103 0.018
dorsal ventral pattern formation GO:0009953 133 0.018
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.018
chemotaxis GO:0006935 249 0.017
dna integrity checkpoint GO:0031570 81 0.017
digestive tract development GO:0048565 149 0.017
protein complex assembly GO:0006461 200 0.017
chemosensory behavior GO:0007635 106 0.017
regulation of cell proliferation GO:0042127 163 0.017
salivary gland histolysis GO:0035070 88 0.017
response to lipopolysaccharide GO:0032496 4 0.017
negative regulation of cellular component organization GO:0051129 108 0.017
immune response regulating signaling pathway GO:0002764 2 0.017
protein localization GO:0008104 284 0.017
secretion by cell GO:0032940 101 0.016
regulation of cell cycle process GO:0010564 181 0.016
mitotic spindle organization GO:0007052 220 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
respiratory system development GO:0060541 213 0.016
histone modification GO:0016570 106 0.016
positive regulation of catabolic process GO:0009896 105 0.016
multi organism behavior GO:0051705 175 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
central nervous system development GO:0007417 201 0.016
regulation of growth GO:0040008 233 0.016
tissue death GO:0016271 102 0.016
connective tissue development GO:0061448 3 0.016
ameboidal type cell migration GO:0001667 151 0.015
rna catabolic process GO:0006401 37 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.015
tissue migration GO:0090130 155 0.015
negative regulation of receptor activity GO:2000272 3 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
aging GO:0007568 143 0.015
protein import GO:0017038 55 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
regulation of apoptotic process GO:0042981 130 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
immune response activating signal transduction GO:0002757 2 0.015
adult locomotory behavior GO:0008344 76 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
regulation of mrna metabolic process GO:1903311 72 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
secretion GO:0046903 109 0.015
pattern recognition receptor signaling pathway GO:0002221 2 0.014
imaginal disc pattern formation GO:0007447 91 0.014
regulation of organ morphogenesis GO:2000027 78 0.014
digestive system development GO:0055123 149 0.014
telencephalon development GO:0021537 2 0.014
meiotic cell cycle GO:0051321 171 0.014
regulation of catalytic activity GO:0050790 185 0.014
neuron projection guidance GO:0097485 241 0.014
regulation of multi organism process GO:0043900 131 0.014
mitotic dna integrity checkpoint GO:0044774 75 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
taxis GO:0042330 304 0.013
head development GO:0060322 135 0.013
embryonic morphogenesis GO:0048598 206 0.013
multi multicellular organism process GO:0044706 123 0.013
cellular catabolic process GO:0044248 372 0.013
synaptic growth at neuromuscular junction GO:0051124 119 0.013
gene silencing GO:0016458 138 0.013
autophagic cell death GO:0048102 83 0.013
response to nutrient levels GO:0031667 114 0.013
g2 dna damage checkpoint GO:0031572 69 0.013
epithelial structure maintenance GO:0010669 17 0.013
protein targeting to nucleus GO:0044744 51 0.013
mapk cascade GO:0000165 107 0.013
cellular response to organic substance GO:0071310 132 0.013
oocyte axis specification GO:0007309 108 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of nervous system development GO:0051960 248 0.013
chromosome segregation GO:0007059 157 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
single organism catabolic process GO:0044712 228 0.013
brain development GO:0007420 120 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
regulation of intracellular transport GO:0032386 64 0.013
single organism nuclear import GO:1902593 51 0.013
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
negative regulation of translation GO:0017148 28 0.012
regulation of programmed cell death GO:0043067 152 0.012
epithelial cell development GO:0002064 274 0.012
positive regulation of transport GO:0051050 92 0.012
heterocycle catabolic process GO:0046700 166 0.012
chromatin organization GO:0006325 207 0.012
macromolecular complex assembly GO:0065003 256 0.012
intracellular protein transport GO:0006886 104 0.012
cytoplasmic transport GO:0016482 130 0.012
innate immune response activating signal transduction GO:0002758 2 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
translation GO:0006412 69 0.012
centrosome organization GO:0051297 163 0.012
mitotic cytokinesis GO:0000281 50 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
organelle fission GO:0048285 340 0.012
maintenance of location GO:0051235 73 0.012
transmembrane transport GO:0055085 139 0.012
apoptotic process GO:0006915 159 0.012
regulation of protein transport GO:0051223 57 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
modification dependent protein catabolic process GO:0019941 78 0.012
axis specification GO:0009798 167 0.012
regulation of cell shape GO:0008360 113 0.012
rna 3 end processing GO:0031123 45 0.012
centrosome duplication GO:0051298 121 0.012
regulation of cellular catabolic process GO:0031329 157 0.011
response to oxidative stress GO:0006979 86 0.011
regulation of mapk cascade GO:0043408 92 0.011
regulation of phosphorylation GO:0042325 147 0.011
response to oxygen containing compound GO:1901700 200 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
muscle organ development GO:0007517 127 0.011
regulation of cell development GO:0060284 215 0.011
positive regulation of molecular function GO:0044093 136 0.011
regulation of catabolic process GO:0009894 170 0.011
response to endogenous stimulus GO:0009719 119 0.011
nuclear import GO:0051170 51 0.011
developmental pigmentation GO:0048066 68 0.011
ras protein signal transduction GO:0007265 88 0.011
cellular ion homeostasis GO:0006873 39 0.011
eggshell formation GO:0030703 105 0.011
anterior posterior pattern specification GO:0009952 136 0.011
regulation of behavior GO:0050795 75 0.011
memory GO:0007613 94 0.011
positive regulation of immune system process GO:0002684 68 0.011
instar larval development GO:0002168 55 0.011
axon development GO:0061564 297 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
cellularization GO:0007349 90 0.011
signal release GO:0023061 49 0.011
negative regulation of developmental process GO:0051093 201 0.011
digestive tract morphogenesis GO:0048546 127 0.011
nuclear transcribed mrna catabolic process GO:0000956 24 0.011
regulation of intracellular protein transport GO:0033157 46 0.011
response to temperature stimulus GO:0009266 106 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
regulation of translation GO:0006417 56 0.011
learning GO:0007612 75 0.011
mitotic cell cycle checkpoint GO:0007093 88 0.011
olfactory learning GO:0008355 56 0.010
ribosomal large subunit biogenesis GO:0042273 1 0.010
protein localization to nucleus GO:0034504 55 0.010
cellular homeostasis GO:0019725 80 0.010
regulation of wnt signaling pathway GO:0030111 68 0.010
ion transmembrane transport GO:0034220 122 0.010
negative regulation of cell death GO:0060548 81 0.010
camera type eye development GO:0043010 4 0.010
regulation of chromosome organization GO:0033044 64 0.010
jak stat cascade GO:0007259 49 0.010
regulation of cytoplasmic transport GO:1903649 47 0.010
regulation of defense response GO:0031347 102 0.010
negative regulation of cell proliferation GO:0008285 69 0.010
negative regulation of rna biosynthetic process GO:1902679 240 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010

Not1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
artery disease DOID:0050828 0 0.016
vascular disease DOID:178 0 0.016
cardiovascular system disease DOID:1287 0 0.016