Drosophila melanogaster

194 known processes

ptc (Dmel_CG2411)

patched

(Aliases: Ptch,pat,dPtc,l(2)k02507,Ptc,PTC,ptch,CG2411,Conf,rubr,BcDNA:RH36596,Dmel\CG2411,Ptc_Dm,tuf)

ptc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ morphogenesis GO:0090596 260 0.990
eye photoreceptor cell differentiation GO:0001754 145 0.974
morphogenesis of a branching epithelium GO:0061138 45 0.965
Mouse
wing disc morphogenesis GO:0007472 344 0.958
regionalization GO:0003002 416 0.944
Human Zebrafish Mouse
muscle structure development GO:0061061 224 0.942
Zebrafish
imaginal disc derived appendage morphogenesis GO:0035114 395 0.940
axon guidance GO:0007411 233 0.938
neuron projection guidance GO:0097485 241 0.937
branching morphogenesis of an epithelial tube GO:0048754 45 0.927
Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.922
bolwig s organ development GO:0055034 8 0.920
establishment of localization in cell GO:0051649 402 0.916
epithelial cell migration open tracheal system GO:0007427 32 0.895
larval development GO:0002164 104 0.883
Worm
compound eye morphogenesis GO:0001745 249 0.866
regulation of cell differentiation GO:0045595 302 0.864
Human
appendage morphogenesis GO:0035107 397 0.856
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.845
Human
striated muscle cell development GO:0055002 50 0.841
striated muscle cell differentiation GO:0051146 90 0.840
eye morphogenesis GO:0048592 260 0.838
imaginal disc derived appendage development GO:0048737 399 0.834
tube development GO:0035295 244 0.826
Human Mouse
muscle cell development GO:0055001 50 0.822
regulation of muscle organ development GO:0048634 13 0.787
Zebrafish
central nervous system development GO:0007417 201 0.778
Mouse
establishment of tissue polarity GO:0007164 87 0.773
regulation of growth GO:0040008 233 0.763
Mouse Worm
eye development GO:0001654 323 0.747
cellular macromolecule localization GO:0070727 220 0.734
tube morphogenesis GO:0035239 191 0.733
Mouse
single organism intracellular transport GO:1902582 207 0.733
digestive tract morphogenesis GO:0048546 127 0.719
morphogenesis of an epithelium GO:0002009 276 0.715
Mouse
appendage development GO:0048736 401 0.714
imaginal disc derived wing morphogenesis GO:0007476 337 0.710
embryonic pattern specification GO:0009880 174 0.696
Mouse
gliogenesis GO:0042063 80 0.696
anterior posterior pattern specification GO:0009952 136 0.687
embryonic morphogenesis GO:0048598 206 0.679
Mouse
single organism cellular localization GO:1902580 180 0.662
protein transport GO:0015031 155 0.658
motor neuron axon guidance GO:0008045 58 0.656
blastoderm segmentation GO:0007350 159 0.636
regulation of cell development GO:0060284 215 0.623
intracellular protein transport GO:0006886 104 0.619
stem cell differentiation GO:0048863 117 0.616
Zebrafish
positive regulation of cell death GO:0010942 69 0.611
spinal cord dorsal ventral patterning GO:0021513 1 0.589
eye photoreceptor cell development GO:0042462 81 0.589
muscle cell differentiation GO:0042692 103 0.568
tissue migration GO:0090130 155 0.563
transcription from rna polymerase ii promoter GO:0006366 368 0.561
Human
post embryonic appendage morphogenesis GO:0035120 385 0.560
imaginal disc derived wing vein specification GO:0007474 48 0.557
negative regulation of developmental process GO:0051093 201 0.553
Human Zebrafish Mouse
segmentation GO:0035282 207 0.551
photoreceptor cell differentiation GO:0046530 170 0.549
myotube differentiation GO:0014902 46 0.530
regulation of neurogenesis GO:0050767 158 0.525
stem cell development GO:0048864 79 0.524
negative regulation of growth GO:0045926 84 0.524
Mouse
morphogenesis of an epithelial bud GO:0060572 3 0.509
myoblast fusion GO:0007520 43 0.507
tissue morphogenesis GO:0048729 297 0.497
Zebrafish Mouse
gland development GO:0048732 191 0.496
Mouse
positive regulation of neurogenesis GO:0050769 41 0.490
telencephalon development GO:0021537 2 0.489
digestive tract development GO:0048565 149 0.481
organic substance catabolic process GO:1901575 308 0.480
compound eye development GO:0048749 307 0.469
synapse organization GO:0050808 196 0.459
myotube cell development GO:0014904 3 0.457
macromolecule catabolic process GO:0009057 161 0.453
nuclear transport GO:0051169 72 0.451
regulation of protein localization GO:0032880 76 0.442
developmental growth GO:0048589 280 0.437
Mouse Worm
positive regulation of nervous system development GO:0051962 69 0.436
camera type eye photoreceptor cell differentiation GO:0060219 2 0.431
forebrain development GO:0030900 2 0.427
positive regulation of gene expression GO:0010628 290 0.426
ventral midline development GO:0007418 9 0.424
axis specification GO:0009798 167 0.420
Mouse
negative regulation of cell development GO:0010721 62 0.417
negative regulation of cell proliferation GO:0008285 69 0.414
Mouse
pigmentation GO:0043473 75 0.410
renal tubule development GO:0061326 64 0.404
Mouse
regulation of multicellular organismal development GO:2000026 414 0.404
protein localization GO:0008104 284 0.402
secretion GO:0046903 109 0.398
negative regulation of cell cycle process GO:0010948 109 0.398
regulation of anatomical structure morphogenesis GO:0022603 242 0.392
striated muscle tissue development GO:0014706 27 0.387
genital disc development GO:0035215 44 0.379
body morphogenesis GO:0010171 2 0.378
androgen metabolic process GO:0008209 1 0.374
axon development GO:0061564 297 0.372
protein catabolic process GO:0030163 101 0.370
organic substance transport GO:0071702 257 0.369
chromatin organization GO:0006325 207 0.366
negative regulation of developmental growth GO:0048640 64 0.359
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.357
Human
cranial nerve development GO:0021545 1 0.355
positive regulation of rna metabolic process GO:0051254 271 0.355
negative regulation of nervous system development GO:0051961 92 0.354
regulation of neuron projection development GO:0010975 69 0.351
eye antennal disc morphogenesis GO:0007455 34 0.350
neuron fate specification GO:0048665 12 0.349
formation of anatomical boundary GO:0048859 37 0.344
positive regulation of nucleic acid templated transcription GO:1903508 266 0.341
cardioblast cell fate specification GO:0042685 9 0.335
regulation of developmental growth GO:0048638 174 0.330
Mouse Worm
gastrulation GO:0007369 70 0.328
regulation of programmed cell death GO:0043067 152 0.325
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.319
Human
regulation of cell size GO:0008361 63 0.315
establishment of planar polarity GO:0001736 87 0.313
positive regulation of rna biosynthetic process GO:1902680 266 0.307
intracellular transport GO:0046907 228 0.305
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.303
negative regulation of cell cycle GO:0045786 116 0.297
negative regulation of neurogenesis GO:0050768 53 0.296
protein import GO:0017038 55 0.294
organelle assembly GO:0070925 198 0.289
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.287
regulation of nervous system development GO:0051960 248 0.283
protein localization to nucleus GO:0034504 55 0.282
regulation of transport GO:0051049 181 0.281
organic hydroxy compound metabolic process GO:1901615 83 0.277
genital disc anterior posterior pattern formation GO:0035224 8 0.277
camera type eye morphogenesis GO:0048593 2 0.276
Zebrafish
digestive system development GO:0055123 149 0.275
negative regulation of biosynthetic process GO:0009890 277 0.275
Human
positive regulation of cellular component organization GO:0051130 156 0.266
purine nucleoside catabolic process GO:0006152 112 0.266
response to metal ion GO:0010038 23 0.265
anterior posterior axis specification GO:0009948 109 0.261
eye photoreceptor cell fate commitment GO:0042706 37 0.258
ameboidal type cell migration GO:0001667 151 0.256
positive regulation of biosynthetic process GO:0009891 316 0.254
regulation of cellular component biogenesis GO:0044087 201 0.252
developmental growth involved in morphogenesis GO:0060560 65 0.250
wound healing GO:0042060 75 0.250
photoreceptor cell fate commitment GO:0046552 41 0.249
neural precursor cell proliferation GO:0061351 75 0.245
positive regulation of programmed cell death GO:0043068 62 0.245
cell growth GO:0016049 108 0.244
protein import into nucleus GO:0006606 51 0.243
organ induction GO:0001759 3 0.241
cellular response to organic substance GO:0071310 132 0.240
Human Mouse
imaginal disc derived leg morphogenesis GO:0007480 80 0.231
protein localization to organelle GO:0033365 82 0.230
muscle cell fate specification GO:0042694 7 0.227
neuron fate determination GO:0048664 1 0.227
mesoderm development GO:0007498 78 0.226
apoptotic process GO:0006915 159 0.225
response to oxygen containing compound GO:1901700 200 0.225
Human Mouse
labial disc development GO:0035217 4 0.224
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.222
negative regulation of transcription dna templated GO:0045892 237 0.220
Human
morphogenesis of a polarized epithelium GO:0001738 93 0.220
morphogenesis of a branching structure GO:0001763 45 0.219
Mouse
kidney development GO:0001822 3 0.219
Mouse
cell proliferation GO:0008283 299 0.218
Mouse
positive regulation of growth GO:0045927 75 0.217
Worm
regulation of neuron differentiation GO:0045664 103 0.211
regulation of cellular catabolic process GO:0031329 157 0.210
regulation of axon extension GO:0030516 8 0.210
catabolic process GO:0009056 409 0.208
hindgut morphogenesis GO:0007442 58 0.206
chemotaxis GO:0006935 249 0.205
positive regulation of nucleoside metabolic process GO:0045979 47 0.204
segment polarity determination GO:0007367 25 0.203
neuroblast proliferation GO:0007405 74 0.194
skeletal muscle organ development GO:0060538 48 0.193
macromolecular complex assembly GO:0065003 256 0.192
eye antennal disc development GO:0035214 60 0.191
cellular component assembly involved in morphogenesis GO:0010927 151 0.190
skin development GO:0043588 65 0.189
Mouse
regulation of dna metabolic process GO:0051052 34 0.188
negative regulation of cardioblast differentiation GO:0051892 7 0.188
cellular response to endogenous stimulus GO:0071495 80 0.186
neuroblast development GO:0014019 13 0.186
apoptotic process involved in morphogenesis GO:0060561 3 0.186
protein targeting GO:0006605 64 0.183
neuron fate commitment GO:0048663 50 0.182
inter male aggressive behavior GO:0002121 60 0.175
branching involved in open tracheal system development GO:0060446 45 0.173
cell fate specification involved in pattern specification GO:0060573 8 0.171
biological adhesion GO:0022610 138 0.170
compound eye photoreceptor development GO:0042051 78 0.167
neuroblast differentiation GO:0014016 29 0.166
neural retina development GO:0003407 4 0.166
nephron development GO:0072006 3 0.166
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.163
Human
cell fate specification GO:0001708 71 0.162
retinal ganglion cell axon guidance GO:0031290 12 0.161
Zebrafish
establishment of protein localization GO:0045184 163 0.158
glial cell migration GO:0008347 31 0.158
gastrulation with mouth forming first GO:0001703 36 0.157
organelle localization GO:0051640 148 0.157
negative regulation of cellular biosynthetic process GO:0031327 277 0.155
Human
gastrulation involving germ band extension GO:0010004 36 0.154
hindgut development GO:0061525 58 0.153
regulation of anatomical structure size GO:0090066 163 0.153
organ formation GO:0048645 39 0.149
positive regulation of nucleotide metabolic process GO:0045981 55 0.144
regulation of protein transport GO:0051223 57 0.143
epithelial tube morphogenesis GO:0060562 88 0.143
Mouse
gonadal mesoderm development GO:0007506 8 0.142
cellular response to chemical stimulus GO:0070887 199 0.140
Human Mouse
regulation of cell proliferation GO:0042127 163 0.139
Mouse
malpighian tubule morphogenesis GO:0007443 44 0.137
nephron epithelium development GO:0072009 3 0.137
Mouse
axon extension GO:0048675 32 0.134
larval somatic muscle development GO:0007526 19 0.134
regulation of cell fate commitment GO:0010453 29 0.133
positive regulation of signaling GO:0023056 243 0.131
regulation of organelle organization GO:0033043 196 0.131
epidermal cell differentiation GO:0009913 51 0.129
secretion by cell GO:0032940 101 0.128
cellular catabolic process GO:0044248 372 0.128
nerve development GO:0021675 6 0.127
regulation of localization GO:0032879 275 0.126
central nervous system projection neuron axonogenesis GO:0021952 6 0.126
determination of bilateral symmetry GO:0009855 13 0.126
enzyme linked receptor protein signaling pathway GO:0007167 179 0.124
regulation of reproductive process GO:2000241 54 0.124
regulation of synapse structure and activity GO:0050803 128 0.123
cardioblast differentiation GO:0010002 20 0.123
Zebrafish
regulation of cell cycle process GO:0010564 181 0.122
positive regulation of multicellular organismal process GO:0051240 143 0.120
Worm
larval lymph gland hemocyte differentiation GO:0035168 11 0.119
central nervous system neuron differentiation GO:0021953 8 0.116
Mouse
establishment or maintenance of cell polarity GO:0007163 167 0.115
determination of genital disc primordium GO:0035225 10 0.113
single organism nuclear import GO:1902593 51 0.113
protein processing GO:0016485 68 0.112
Mouse
positive regulation of gtp catabolic process GO:0033126 43 0.112
gland morphogenesis GO:0022612 145 0.109
Mouse
dendrite morphogenesis GO:0048813 199 0.108
positive regulation of gtpase activity GO:0043547 43 0.108
mesodermal cell fate specification GO:0007501 2 0.105
glandular epithelial cell differentiation GO:0002067 1 0.105
exocrine system development GO:0035272 162 0.105
axonogenesis GO:0007409 290 0.105
positive regulation of protein transport GO:0051222 37 0.104
regulation of cytoplasmic transport GO:1903649 47 0.104
negative regulation of signaling GO:0023057 219 0.104
enteroendocrine cell differentiation GO:0035883 1 0.104
spiracle morphogenesis open tracheal system GO:0035277 22 0.103
regulation of cell cycle GO:0051726 291 0.103
localization of cell GO:0051674 257 0.103
axis elongation GO:0003401 3 0.102
regulation of mitotic cell cycle GO:0007346 190 0.101
establishment of protein localization to organelle GO:0072594 62 0.100
genital disc pattern formation GO:0035221 8 0.099
positive regulation of response to stimulus GO:0048584 323 0.099
signal transduction downstream of smoothened GO:0007227 5 0.098
regulation of heart morphogenesis GO:2000826 3 0.096
cell fate determination GO:0001709 91 0.095
regulation of glial cell differentiation GO:0045685 1 0.094
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.093
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.093
hindbrain development GO:0030902 2 0.093
membrane organization GO:0061024 112 0.093
Human
brain development GO:0007420 120 0.092
Mouse
cell maturation GO:0048469 144 0.092
negative regulation of cell communication GO:0010648 223 0.092
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.092
Human
positive regulation of muscle organ development GO:0048636 6 0.092
vesicle mediated transport GO:0016192 381 0.091
aromatic compound catabolic process GO:0019439 166 0.091
cell migration involved in gastrulation GO:0042074 9 0.089
actin filament based process GO:0030029 220 0.088
cellular macromolecule catabolic process GO:0044265 136 0.088
regulation of bmp signaling pathway GO:0030510 23 0.088
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.087
regulation of nucleoside metabolic process GO:0009118 50 0.087
connective tissue development GO:0061448 3 0.086
specification of symmetry GO:0009799 13 0.086
single organism biosynthetic process GO:0044711 206 0.085
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.084
cellular nitrogen compound catabolic process GO:0044270 165 0.084
dendrite guidance GO:0070983 21 0.084
regulation of dendrite morphogenesis GO:0048814 28 0.082
negative regulation of cell cycle phase transition GO:1901988 103 0.082
substrate dependent cell migration GO:0006929 3 0.082
molting cycle GO:0042303 56 0.081
Mouse Worm
spinal cord development GO:0021510 1 0.081
Mouse
organic cyclic compound catabolic process GO:1901361 168 0.079
regulation of apoptotic process GO:0042981 130 0.079
cell cell signaling involved in cell fate commitment GO:0045168 210 0.079
regulation of striated muscle tissue development GO:0016202 5 0.078
glial cell development GO:0021782 27 0.078
ubiquitin dependent protein catabolic process GO:0006511 78 0.078
negative regulation of smoothened signaling pathway GO:0045879 16 0.078
regulation of cell projection organization GO:0031344 92 0.077
regulation of cellular localization GO:0060341 136 0.077
regulation of cardioblast differentiation GO:0051890 9 0.076
growth GO:0040007 359 0.076
Mouse Worm
blood circulation GO:0008015 26 0.076
cellular response to hormone stimulus GO:0032870 44 0.076
respiratory system development GO:0060541 213 0.075
negative regulation of multicellular organismal process GO:0051241 142 0.075
Human Zebrafish Mouse
eye pigmentation GO:0048069 43 0.075
stem cell maintenance GO:0019827 67 0.075
muscle organ development GO:0007517 127 0.074
Zebrafish
cell motility GO:0048870 251 0.073
positive regulation of cellular catabolic process GO:0031331 95 0.072
cellular hormone metabolic process GO:0034754 23 0.072
response to organic cyclic compound GO:0014070 89 0.072
Human Mouse
r3 r4 cell differentiation GO:0048056 12 0.071
muscle organ morphogenesis GO:0048644 7 0.071
muscle tissue development GO:0060537 30 0.071
developmental pigmentation GO:0048066 68 0.071
oocyte development GO:0048599 124 0.070
purine nucleotide catabolic process GO:0006195 109 0.070
hair cell differentiation GO:0035315 47 0.070
protein complex assembly GO:0006461 200 0.069
regulation of organ growth GO:0046620 42 0.069
negative regulation of neuron differentiation GO:0045665 16 0.067
formation of primary germ layer GO:0001704 24 0.067
regulation of eye pigmentation GO:0048073 7 0.067
regulation of dendrite development GO:0050773 37 0.067
cellular protein localization GO:0034613 160 0.067
bolwig s organ morphogenesis GO:0001746 8 0.066
positive regulation of developmental process GO:0051094 143 0.066
Worm
organic hydroxy compound biosynthetic process GO:1901617 21 0.066
ribonucleoside catabolic process GO:0042454 112 0.066
regulation of steroid metabolic process GO:0019218 2 0.066
carbohydrate derivative metabolic process GO:1901135 217 0.066
cell migration GO:0016477 238 0.065
determination of dorsal ventral asymmetry GO:0048262 3 0.065
hematopoietic or lymphoid organ development GO:0048534 57 0.065
regulation of axon extension involved in axon guidance GO:0048841 4 0.065
regulation of epithelial cell proliferation GO:0050678 4 0.064
Mouse
epithelial cell development GO:0002064 274 0.063
regulation of protein catabolic process GO:0042176 55 0.063
glial cell differentiation GO:0010001 35 0.062
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.061
embryonic hindgut morphogenesis GO:0048619 48 0.061
response to organic substance GO:0010033 284 0.060
Human Mouse
oenocyte differentiation GO:0001742 8 0.060
chaeta morphogenesis GO:0008407 42 0.060
bmp signaling pathway GO:0030509 27 0.060
cardiocyte differentiation GO:0035051 29 0.060
Zebrafish
response to inorganic substance GO:0010035 44 0.060
Mouse
developmental cell growth GO:0048588 52 0.059
determination of ventral identity GO:0048264 1 0.059
protein targeting to nucleus GO:0044744 51 0.059
morphogenesis of an epithelial fold GO:0060571 6 0.058
notch signaling pathway GO:0007219 120 0.058
regulation of cardioblast cell fate specification GO:0042686 8 0.057
regulation of organ formation GO:0003156 3 0.057
anterior commissure morphogenesis GO:0021960 2 0.056
regulation of synapse assembly GO:0051963 94 0.056
malpighian tubule development GO:0072002 64 0.055
positive regulation of developmental growth GO:0048639 62 0.055
Worm
stem cell fate commitment GO:0048865 25 0.055
peptidyl amino acid modification GO:0018193 105 0.055
cellular response to peptide hormone stimulus GO:0071375 28 0.055
protein complex biogenesis GO:0070271 201 0.054
head development GO:0060322 135 0.054
Mouse
stem cell fate determination GO:0048867 15 0.053
positive regulation of cell development GO:0010720 61 0.053
olfactory behavior GO:0042048 97 0.053
germ cell migration GO:0008354 43 0.053
nephron morphogenesis GO:0072028 3 0.053
Mouse
developmental induction GO:0031128 3 0.052
glial cell fate commitment GO:0021781 3 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.052
developmental maturation GO:0021700 172 0.052
intracellular signal transduction GO:0035556 300 0.052
regulation of intracellular signal transduction GO:1902531 236 0.051
ribonucleoside metabolic process GO:0009119 127 0.051
negative regulation of mitotic cell cycle GO:0045930 109 0.051
negative regulation of cell differentiation GO:0045596 143 0.051
Human
photoreceptor cell development GO:0042461 96 0.050
regulation of cell fate specification GO:0042659 27 0.050
regulation of hemocyte differentiation GO:0045610 22 0.050
regulation of nucleotide catabolic process GO:0030811 48 0.050
cell cycle phase transition GO:0044770 140 0.049
regulation of axonogenesis GO:0050770 32 0.049
regulation of immune system process GO:0002682 176 0.049
cell projection assembly GO:0030031 94 0.049
response to peptide GO:1901652 29 0.049
oocyte differentiation GO:0009994 145 0.048
nephron epithelium morphogenesis GO:0072088 3 0.048
Mouse
positive regulation of protein import into nucleus GO:0042307 21 0.048
positive regulation of cell differentiation GO:0045597 64 0.048
nucleoside catabolic process GO:0009164 112 0.048
salivary gland morphogenesis GO:0007435 145 0.047
regulation of developmental pigmentation GO:0048070 24 0.047
embryonic axis specification GO:0000578 107 0.047
Mouse
regulation of protein import into nucleus GO:0042306 28 0.046
regulation of catalytic activity GO:0050790 185 0.046
regulation of intracellular protein transport GO:0033157 46 0.046
regulation of purine nucleotide metabolic process GO:1900542 62 0.046
cellular protein catabolic process GO:0044257 83 0.046
cellular macromolecular complex assembly GO:0034622 153 0.046
endocytosis GO:0006897 310 0.046
cardiac cell fate specification GO:0060912 10 0.045
cytoplasmic transport GO:0016482 130 0.045
somatic muscle development GO:0007525 66 0.045
spinal cord patterning GO:0021511 1 0.045
lateral inhibition GO:0046331 206 0.044
retina development in camera type eye GO:0060041 4 0.044
Zebrafish
regulation of organ morphogenesis GO:2000027 78 0.044
ras protein signal transduction GO:0007265 88 0.044
cellular response to organonitrogen compound GO:0071417 36 0.043
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.043
negative regulation of apoptotic signaling pathway GO:2001234 5 0.043
anterior posterior axis specification embryo GO:0008595 103 0.043
locomotory behavior GO:0007626 176 0.043
heterocycle catabolic process GO:0046700 166 0.043
ommatidial rotation GO:0016318 20 0.043
cell type specific apoptotic process GO:0097285 38 0.042
extracellular structure organization GO:0043062 46 0.042
guanosine containing compound catabolic process GO:1901069 74 0.042
single organismal cell cell adhesion GO:0016337 45 0.042
death GO:0016265 284 0.041
synaptic transmission GO:0007268 288 0.041
vitamin metabolic process GO:0006766 2 0.040
protein modification by small protein conjugation or removal GO:0070647 106 0.040
regulation of neural precursor cell proliferation GO:2000177 35 0.040
proteolysis GO:0006508 192 0.040
chromosome organization GO:0051276 360 0.040
positive regulation of hh target transcription factor activity GO:0007228 5 0.040
purine ribonucleoside catabolic process GO:0046130 112 0.040
immune system development GO:0002520 57 0.040
mushroom body development GO:0016319 70 0.039
embryo development ending in birth or egg hatching GO:0009792 152 0.039
Human Mouse Worm
regulation of cell morphogenesis GO:0022604 163 0.039
wing and notum subfield formation GO:0035309 13 0.039
compound eye photoreceptor fate commitment GO:0001752 36 0.039
establishment of organelle localization GO:0051656 122 0.039
protein maturation GO:0051604 71 0.038
Mouse
glycosyl compound catabolic process GO:1901658 112 0.038
antennal joint development GO:0048098 5 0.038
rna processing GO:0006396 147 0.038
protein ubiquitination GO:0016567 70 0.038
cellular response to peptide GO:1901653 28 0.038
regulation of compound eye photoreceptor development GO:0045314 12 0.037
negative regulation of cell fate specification GO:0009996 15 0.036
nuclear import GO:0051170 51 0.036
renal system development GO:0072001 72 0.036
Human Mouse
antennal morphogenesis GO:0048800 14 0.036
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.036
protein modification by small protein conjugation GO:0032446 79 0.036
nucleobase containing compound catabolic process GO:0034655 165 0.036
renal tubule morphogenesis GO:0061333 44 0.035
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.035
response to ketone GO:1901654 34 0.035
small molecule biosynthetic process GO:0044283 37 0.035
regulation of catabolic process GO:0009894 170 0.035
regulation of neuroblast proliferation GO:1902692 34 0.035
positive regulation of cellular biosynthetic process GO:0031328 316 0.034
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.034
immune system process GO:0002376 347 0.034
phagocytosis GO:0006909 215 0.034
nucleoside phosphate metabolic process GO:0006753 162 0.034
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.034
circulatory system development GO:0072359 82 0.034
Zebrafish Mouse
nephron tubule morphogenesis GO:0072078 3 0.034
Mouse
regulation of stem cell proliferation GO:0072091 40 0.034
cellular protein complex assembly GO:0043623 71 0.033
regulation of cytoskeleton organization GO:0051493 89 0.033
regulation of muscle tissue development GO:1901861 5 0.033
regulation of eye photoreceptor cell development GO:0042478 13 0.033
tripartite regional subdivision GO:0007351 103 0.033
organonitrogen compound catabolic process GO:1901565 128 0.033
positive regulation of cell migration GO:0030335 2 0.033
cellular response to nitrogen compound GO:1901699 51 0.032
regulation of gtpase activity GO:0043087 44 0.032
positive regulation of cell communication GO:0010647 250 0.032
regulation of retinal cell programmed cell death GO:0046668 18 0.032
regulation of sterol transport GO:0032371 1 0.032
Human
oocyte axis specification GO:0007309 108 0.032
kidney epithelium development GO:0072073 3 0.031
Mouse
regulation of establishment of protein localization GO:0070201 61 0.031
kidney morphogenesis GO:0060993 3 0.031
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 108 0.031
head involution GO:0008258 35 0.031
negative regulation of cell death GO:0060548 81 0.031
mitotic nuclear division GO:0007067 213 0.031
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.031

ptc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.176
cancer DOID:162 0 0.097
Human
disease of cellular proliferation DOID:14566 0 0.097
Human
sensory system disease DOID:0050155 0 0.035
eye and adnexa disease DOID:1492 0 0.035
nervous system disease DOID:863 0 0.035
musculoskeletal system disease DOID:17 0 0.031