Drosophila melanogaster

15 known processes

l(2)tid (Dmel_CG5504)

lethal (2) tumorous imaginal discs

(Aliases: l(2)701,l(2)tumorous disc,l(2)tumorous imaginal discs,CG5504,cDNA 10D,Dmel\CG5504,l(2)tud,tid,DnaJ,l(2)td,TID56)

l(2)tid biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular metabolic process GO:0031324 382 0.130
Human
organonitrogen compound metabolic process GO:1901564 318 0.103
Yeast
single organism cellular localization GO:1902580 180 0.074
cellular catabolic process GO:0044248 372 0.061
Yeast
establishment of localization in cell GO:0051649 402 0.060
homeostatic process GO:0042592 199 0.058
mitochondrion organization GO:0007005 65 0.058
Yeast
membrane organization GO:0061024 112 0.057
single organism intracellular transport GO:1902582 207 0.056
eye development GO:0001654 323 0.056
negative regulation of response to stimulus GO:0048585 258 0.051
Human
organic substance catabolic process GO:1901575 308 0.051
Yeast
small molecule metabolic process GO:0044281 305 0.051
Yeast
ribonucleotide metabolic process GO:0009259 145 0.050
Yeast
intracellular protein transmembrane transport GO:0065002 4 0.050
response to organic substance GO:0010033 284 0.049
Human
protein transport GO:0015031 155 0.048
catabolic process GO:0009056 409 0.047
Yeast
establishment of protein localization GO:0045184 163 0.047
cytoplasmic transport GO:0016482 130 0.045
cellular macromolecule localization GO:0070727 220 0.044
purine ribonucleoside metabolic process GO:0046128 127 0.043
Yeast
sensory organ morphogenesis GO:0090596 260 0.043
carbohydrate derivative metabolic process GO:1901135 217 0.041
Yeast
protein localization GO:0008104 284 0.041
intracellular protein transport GO:0006886 104 0.040
cellular macromolecule catabolic process GO:0044265 136 0.040
Yeast
purine ribonucleotide metabolic process GO:0009150 145 0.038
Yeast
purine nucleotide metabolic process GO:0006163 146 0.038
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.037
Yeast
macromolecule catabolic process GO:0009057 161 0.037
Yeast
nucleobase containing small molecule metabolic process GO:0055086 174 0.037
Yeast
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.036
Yeast
organic substance transport GO:0071702 257 0.036
regulation of cellular protein metabolic process GO:0032268 243 0.035
Human
purine containing compound metabolic process GO:0072521 155 0.035
Yeast
regulation of response to stress GO:0080134 200 0.034
Human
cellular protein localization GO:0034613 160 0.033
organelle fission GO:0048285 340 0.032
protein targeting GO:0006605 64 0.032
organelle fusion GO:0048284 46 0.031
protein catabolic process GO:0030163 101 0.031
Yeast
compound eye morphogenesis GO:0001745 249 0.030
lipid metabolic process GO:0006629 121 0.030
dna metabolic process GO:0006259 227 0.030
cell cycle checkpoint GO:0000075 95 0.029
mitotic nuclear division GO:0007067 213 0.029
negative regulation of signal transduction GO:0009968 206 0.028
Human
regulation of catabolic process GO:0009894 170 0.028
Yeast
cell division GO:0051301 248 0.028
cellular nitrogen compound catabolic process GO:0044270 165 0.028
Yeast
negative regulation of signaling GO:0023057 219 0.028
Human
negative regulation of cell communication GO:0010648 223 0.028
Human
single organism catabolic process GO:0044712 228 0.028
Yeast
cellular protein catabolic process GO:0044257 83 0.028
Yeast
intracellular transport GO:0046907 228 0.028
immune response GO:0006955 246 0.027
Human
chromosome organization GO:0051276 360 0.027
embryo development ending in birth or egg hatching GO:0009792 152 0.027
cell proliferation GO:0008283 299 0.027
Human
embryonic development via the syncytial blastoderm GO:0001700 148 0.027
ribonucleoside triphosphate metabolic process GO:0009199 119 0.026
Yeast
nucleobase containing compound catabolic process GO:0034655 165 0.026
Yeast
compound eye development GO:0048749 307 0.025
intracellular protein transmembrane import GO:0044743 4 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.025
larval development GO:0002164 104 0.025
regulation of cellular catabolic process GO:0031329 157 0.025
Yeast
protein complex assembly GO:0006461 200 0.025
ribose phosphate metabolic process GO:0019693 145 0.025
Yeast
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
Yeast
macromolecular complex assembly GO:0065003 256 0.025
negative regulation of biosynthetic process GO:0009890 277 0.024
Human
ribonucleoside triphosphate catabolic process GO:0009203 108 0.023
Yeast
humoral immune response GO:0006959 117 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.023
Human
organophosphate catabolic process GO:0046434 112 0.022
Yeast
cellular response to chemical stimulus GO:0070887 199 0.022
Human
sister chromatid segregation GO:0000819 92 0.022
regulation of molecular function GO:0065009 217 0.022
Human Yeast
negative regulation of intracellular signal transduction GO:1902532 57 0.022
Human
aromatic compound catabolic process GO:0019439 166 0.022
Yeast
regulation of phosphorus metabolic process GO:0051174 210 0.022
Human Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.021
Yeast
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.021
Yeast
endocytosis GO:0006897 310 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
Yeast
regulation of cell cycle process GO:0010564 181 0.021
nucleotide metabolic process GO:0009117 161 0.021
Yeast
nucleoside triphosphate metabolic process GO:0009141 120 0.020
Yeast
single organism membrane organization GO:0044802 93 0.020
single organism biosynthetic process GO:0044711 206 0.020
regulation of protein metabolic process GO:0051246 256 0.020
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
Human
endomembrane system organization GO:0010256 119 0.019
developmental maturation GO:0021700 172 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.019
Yeast
regulation of translation GO:0006417 56 0.019
purine nucleoside metabolic process GO:0042278 127 0.019
Yeast
intracellular signal transduction GO:0035556 300 0.019
Human
response to other organism GO:0051707 293 0.019
nucleotide catabolic process GO:0009166 109 0.019
Yeast
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
Human
protein transmembrane transport GO:0071806 4 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
Yeast
ribonucleoside metabolic process GO:0009119 127 0.018
Yeast
response to biotic stimulus GO:0009607 294 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
Yeast
regulation of multicellular organismal development GO:2000026 414 0.018
regulation of cell cycle phase transition GO:1901987 130 0.017
negative regulation of gene expression GO:0010629 387 0.017
Human
positive regulation of rna biosynthetic process GO:1902680 266 0.017
response to radiation GO:0009314 155 0.017
regulation of organelle organization GO:0033043 196 0.017
translation GO:0006412 69 0.017
heterocycle catabolic process GO:0046700 166 0.017
Yeast
posttranscriptional regulation of gene expression GO:0010608 145 0.017
Human
purine nucleoside catabolic process GO:0006152 112 0.017
Yeast
regulation of localization GO:0032879 275 0.017
autophagy GO:0006914 108 0.017
spindle assembly GO:0051225 80 0.017
death GO:0016265 284 0.017
Human
phagocytosis GO:0006909 215 0.017
purine nucleotide catabolic process GO:0006195 109 0.016
Yeast
regulation of intracellular signal transduction GO:1902531 236 0.016
Human
glycosyl compound metabolic process GO:1901657 127 0.016
Yeast
eye photoreceptor cell differentiation GO:0001754 145 0.016
regulation of cell division GO:0051302 72 0.016
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
Yeast
negative regulation of cell proliferation GO:0008285 69 0.016
Human
segmentation GO:0035282 207 0.016
cell death GO:0008219 279 0.016
Human
organonitrogen compound biosynthetic process GO:1901566 117 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
regulation of catalytic activity GO:0050790 185 0.016
Human Yeast
vesicle mediated transport GO:0016192 381 0.016
oxoacid metabolic process GO:0043436 103 0.016
immune response activating signal transduction GO:0002757 2 0.015
nuclear division GO:0000280 332 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
Yeast
blastoderm segmentation GO:0007350 159 0.015
dna integrity checkpoint GO:0031570 81 0.015
negative regulation of epithelial cell proliferation GO:0050680 4 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
Yeast
eye morphogenesis GO:0048592 260 0.015
aging GO:0007568 143 0.015
programmed cell death GO:0012501 257 0.015
Human
negative regulation of growth GO:0045926 84 0.015
developmental growth GO:0048589 280 0.014
chromosome segregation GO:0007059 157 0.014
establishment of organelle localization GO:0051656 122 0.014
positive regulation of cell motility GO:2000147 3 0.014
response to external biotic stimulus GO:0043207 293 0.014
body morphogenesis GO:0010171 2 0.014
protein targeting to mitochondrion GO:0006626 1 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
Yeast
protein import GO:0017038 55 0.014
regulation of programmed cell death GO:0043067 152 0.014
Human
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
Yeast
spindle organization GO:0007051 253 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
Yeast
cell motility GO:0048870 251 0.014
regulation of cell death GO:0010941 173 0.013
Human
mitotic cell cycle phase transition GO:0044772 138 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
proteolysis GO:0006508 192 0.013
Human Yeast
regulation of cellular response to stress GO:0080135 89 0.013
organic acid metabolic process GO:0006082 103 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
regulation of cell development GO:0060284 215 0.013
purine containing compound catabolic process GO:0072523 112 0.013
Yeast
glycosyl compound catabolic process GO:1901658 112 0.013
Yeast
transmembrane transport GO:0055085 139 0.013
determination of adult lifespan GO:0008340 137 0.013
cell cycle phase transition GO:0044770 140 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
regulation of protein localization GO:0032880 76 0.013
membrane fusion GO:0061025 42 0.013
establishment of protein localization to organelle GO:0072594 62 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
cellular amino acid metabolic process GO:0006520 61 0.012
cytoplasm organization GO:0007028 64 0.012
cell maturation GO:0048469 144 0.012
regulation of transport GO:0051049 181 0.012
dna replication GO:0006260 48 0.012
phosphorylation GO:0016310 294 0.012
Human
kidney development GO:0001822 3 0.012
innate immune response activating signal transduction GO:0002758 2 0.012
translational elongation GO:0006414 4 0.012
positive regulation of molecular function GO:0044093 136 0.012
Human Yeast
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
Human
carboxylic acid metabolic process GO:0019752 92 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
mitotic cytokinesis GO:0000281 50 0.012
regulation of cell cycle GO:0051726 291 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
cellular response to organic substance GO:0071310 132 0.012
Human
regulation of cellular amine metabolic process GO:0033238 3 0.012
organophosphate metabolic process GO:0019637 195 0.012
Yeast
anatomical structure homeostasis GO:0060249 97 0.012
axonogenesis GO:0007409 290 0.012
nucleoside catabolic process GO:0009164 112 0.012
Yeast
regulation of hydrolase activity GO:0051336 97 0.012
Human Yeast
notch signaling pathway GO:0007219 120 0.012
cellular homeostasis GO:0019725 80 0.011
protein localization to organelle GO:0033365 82 0.011
nucleoside metabolic process GO:0009116 127 0.011
Yeast
positive regulation of biosynthetic process GO:0009891 316 0.011
nephron development GO:0072006 3 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
Human Yeast
mitotic sister chromatid segregation GO:0000070 87 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
immune effector process GO:0002252 98 0.011
growth GO:0040007 359 0.011
cellular response to extracellular stimulus GO:0031668 64 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
photoreceptor cell differentiation GO:0046530 170 0.010
response to endoplasmic reticulum stress GO:0034976 28 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
cellular protein modification process GO:0006464 438 0.010
Human
protein modification process GO:0036211 438 0.010
Human
mitotic spindle organization GO:0007052 220 0.010
dna conformation change GO:0071103 105 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
Yeast
tripartite regional subdivision GO:0007351 103 0.010
oocyte differentiation GO:0009994 145 0.010

l(2)tid disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.021
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
integumentary system disease DOID:16 0 0.011
familial hyperlipidemia DOID:1168 0 0.010
lipid metabolism disorder DOID:3146 0 0.010