Drosophila melanogaster

27 known processes

Bro (Dmel_CG7960)

Brother

(Aliases: bro,Dmel\CG7960,CG7960,rpbeta1)

Bro biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage morphogenesis GO:0035107 397 0.079
post embryonic appendage morphogenesis GO:0035120 385 0.061
imaginal disc derived appendage morphogenesis GO:0035114 395 0.052
appendage development GO:0048736 401 0.050
tube development GO:0035295 244 0.049
dendrite morphogenesis GO:0048813 199 0.044
eye development GO:0001654 323 0.043
positive regulation of nucleic acid templated transcription GO:1903508 266 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.040
positive regulation of cellular biosynthetic process GO:0031328 316 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.039
compound eye development GO:0048749 307 0.039
photoreceptor cell differentiation GO:0046530 170 0.038
compound eye morphogenesis GO:0001745 249 0.038
regulation of immune system process GO:0002682 176 0.037
embryonic morphogenesis GO:0048598 206 0.037
tube morphogenesis GO:0035239 191 0.036
ovarian follicle cell development GO:0030707 248 0.035
neurological system process GO:0050877 358 0.034
imaginal disc derived appendage development GO:0048737 399 0.034
negative regulation of response to stimulus GO:0048585 258 0.034
positive regulation of macromolecule metabolic process GO:0010604 405 0.033
regulation of anatomical structure morphogenesis GO:0022603 242 0.033
endocytosis GO:0006897 310 0.033
catabolic process GO:0009056 409 0.033
small molecule metabolic process GO:0044281 305 0.032
axon development GO:0061564 297 0.032
vesicle mediated transport GO:0016192 381 0.032
cell division GO:0051301 248 0.031
single organism behavior GO:0044708 391 0.031
columnar cuboidal epithelial cell development GO:0002066 249 0.031
gland development GO:0048732 191 0.031
dendrite development GO:0016358 204 0.030
imaginal disc derived wing morphogenesis GO:0007476 337 0.030
cell proliferation GO:0008283 299 0.030
negative regulation of signaling GO:0023057 219 0.030
regionalization GO:0003002 416 0.030
negative regulation of gene expression GO:0010629 387 0.030
cell cell signaling involved in cell fate commitment GO:0045168 210 0.030
cell death GO:0008219 279 0.029
protein modification process GO:0036211 438 0.029
eye morphogenesis GO:0048592 260 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.028
connective tissue development GO:0061448 3 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
regulation of cell cycle GO:0051726 291 0.028
organic substance catabolic process GO:1901575 308 0.027
wing disc morphogenesis GO:0007472 344 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.026
negative regulation of signal transduction GO:0009968 206 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
embryonic development via the syncytial blastoderm GO:0001700 148 0.025
sensory organ morphogenesis GO:0090596 260 0.025
positive regulation of response to stimulus GO:0048584 323 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.025
gastrulation involving germ band extension GO:0010004 36 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
gastrulation with mouth forming first GO:0001703 36 0.024
positive regulation of transcription dna templated GO:0045893 266 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.023
tissue morphogenesis GO:0048729 297 0.023
behavioral response to pain GO:0048266 3 0.023
phagocytosis GO:0006909 215 0.022
compound eye photoreceptor development GO:0042051 78 0.022
epithelial cell development GO:0002064 274 0.022
regulation of cell differentiation GO:0045595 302 0.022
lateral inhibition GO:0046331 206 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
digestive tract development GO:0048565 149 0.021
cellular protein modification process GO:0006464 438 0.021
cellular catabolic process GO:0044248 372 0.021
chemotaxis GO:0006935 249 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
camera type eye development GO:0043010 4 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.020
negative regulation of cell communication GO:0010648 223 0.020
spindle organization GO:0007051 253 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.020
oxoacid metabolic process GO:0043436 103 0.020
organelle assembly GO:0070925 198 0.020
response to oxygen containing compound GO:1901700 200 0.020
axon guidance GO:0007411 233 0.020
proteolysis GO:0006508 192 0.020
synaptic transmission GO:0007268 288 0.020
body morphogenesis GO:0010171 2 0.020
cell migration GO:0016477 238 0.020
regulation of cell proliferation GO:0042127 163 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.019
eye photoreceptor cell differentiation GO:0001754 145 0.019
regulation of cell development GO:0060284 215 0.019
amine metabolic process GO:0009308 12 0.019
nuclear division GO:0000280 332 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
salivary gland morphogenesis GO:0007435 145 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
taxis GO:0042330 304 0.019
cellular response to organic substance GO:0071310 132 0.019
programmed cell death GO:0012501 257 0.019
positive regulation of signaling GO:0023056 243 0.018
exocrine system development GO:0035272 162 0.018
developmental programmed cell death GO:0010623 138 0.018
forebrain development GO:0030900 2 0.018
negative regulation of developmental process GO:0051093 201 0.018
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
positive regulation of signal transduction GO:0009967 223 0.018
negative regulation of rna metabolic process GO:0051253 251 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
chromosome organization GO:0051276 360 0.018
photoreceptor cell development GO:0042461 96 0.018
single organism catabolic process GO:0044712 228 0.018
digestive tract morphogenesis GO:0048546 127 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
ethanolamine containing compound metabolic process GO:0042439 4 0.018
regulation of cell cycle process GO:0010564 181 0.018
retina development in camera type eye GO:0060041 4 0.018
immune system process GO:0002376 347 0.018
morphogenesis of an epithelium GO:0002009 276 0.017
regulation of organ morphogenesis GO:2000027 78 0.017
positive regulation of cell migration GO:0030335 2 0.017
smoothened signaling pathway GO:0007224 49 0.017
actin cytoskeleton organization GO:0030036 206 0.017
salivary gland development GO:0007431 162 0.017
organic acid metabolic process GO:0006082 103 0.017
compound eye photoreceptor cell differentiation GO:0001751 140 0.017
regulation of protein metabolic process GO:0051246 256 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
muscle cell differentiation GO:0042692 103 0.017
organic substance transport GO:0071702 257 0.017
muscle structure development GO:0061061 224 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
leg disc development GO:0035218 92 0.017
segmentation GO:0035282 207 0.017
muscle organ development GO:0007517 127 0.017
organophosphate metabolic process GO:0019637 195 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
gland morphogenesis GO:0022612 145 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
biological adhesion GO:0022610 138 0.016
regulation of organelle organization GO:0033043 196 0.016
hematopoietic progenitor cell differentiation GO:0002244 1 0.016
response to abiotic stimulus GO:0009628 341 0.016
cell motility GO:0048870 251 0.016
establishment of localization in cell GO:0051649 402 0.016
gastrulation GO:0007369 70 0.016
developmental maturation GO:0021700 172 0.016
cholesterol transport GO:0030301 2 0.016
macromolecular complex assembly GO:0065003 256 0.016
r7 cell differentiation GO:0045466 43 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
organelle fission GO:0048285 340 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
actin filament organization GO:0007015 126 0.015
cellular amine metabolic process GO:0044106 12 0.015
single organism biosynthetic process GO:0044711 206 0.015
phosphorylation GO:0016310 294 0.015
cellular ketone metabolic process GO:0042180 24 0.015
spermatogenesis GO:0007283 200 0.015
positive regulation of gene expression GO:0010628 290 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
positive regulation of cell motility GO:2000147 3 0.015
homeostatic process GO:0042592 199 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
axonogenesis GO:0007409 290 0.015
macromolecule catabolic process GO:0009057 161 0.015
ras protein signal transduction GO:0007265 88 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
cellular homeostasis GO:0019725 80 0.014
heterocycle catabolic process GO:0046700 166 0.014
axis specification GO:0009798 167 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
response to lipopolysaccharide GO:0032496 4 0.014
digestive system development GO:0055123 149 0.014
protein complex biogenesis GO:0070271 201 0.014
regulation of nervous system development GO:0051960 248 0.014
positive regulation of lipid storage GO:0010884 4 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
localization of cell GO:0051674 257 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
immune response activating signal transduction GO:0002757 2 0.014
response to organophosphorus GO:0046683 2 0.014
response to wounding GO:0009611 94 0.014
limb development GO:0060173 1 0.014
response to ecdysone GO:0035075 34 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
dorsal closure GO:0007391 79 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
regulation of protein modification process GO:0031399 112 0.014
regulation of neuron differentiation GO:0045664 103 0.014
eye photoreceptor cell development GO:0042462 81 0.014
epithelial cell migration GO:0010631 148 0.013
negative regulation of nervous system development GO:0051961 92 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
endomembrane system organization GO:0010256 119 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
intracellular signal transduction GO:0035556 300 0.013
response to organic substance GO:0010033 284 0.013
regulation of molecular function GO:0065009 217 0.013
wnt signaling pathway GO:0016055 98 0.013
response to copper ion GO:0046688 4 0.013
sterol homeostasis GO:0055092 4 0.013
developmental growth GO:0048589 280 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
cell maturation GO:0048469 144 0.013
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.013
regulation of apoptotic process GO:0042981 130 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
positive regulation of cell communication GO:0010647 250 0.013
kidney development GO:0001822 3 0.013
lipid metabolic process GO:0006629 121 0.013
morphogenesis of a polarized epithelium GO:0001738 93 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
mitotic spindle organization GO:0007052 220 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
eggshell formation GO:0030703 105 0.013
hindbrain development GO:0030902 2 0.013
cation transmembrane transport GO:0098655 88 0.013
cholesterol homeostasis GO:0042632 3 0.013
tissue migration GO:0090130 155 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
mesenchymal cell development GO:0014031 1 0.013
tissue death GO:0016271 102 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
morphogenesis of embryonic epithelium GO:0016331 94 0.013
regulation of localization GO:0032879 275 0.012
telencephalon development GO:0021537 2 0.012
intracellular transport GO:0046907 228 0.012
death GO:0016265 284 0.012
defense response GO:0006952 300 0.012
chromosome segregation GO:0007059 157 0.012
meiotic cell cycle GO:0051321 171 0.012
malpighian tubule development GO:0072002 64 0.012
anatomical structure homeostasis GO:0060249 97 0.012
regulation of catalytic activity GO:0050790 185 0.012
response to monosaccharide GO:0034284 4 0.012
regulation of anatomical structure size GO:0090066 163 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
protein complex assembly GO:0006461 200 0.012
aromatic compound catabolic process GO:0019439 166 0.012
chorion containing eggshell formation GO:0007304 105 0.012
neuron projection guidance GO:0097485 241 0.012
embryonic hindgut morphogenesis GO:0048619 48 0.012
autophagic cell death GO:0048102 83 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
defense response to bacterium GO:0042742 178 0.012
regulation of transport GO:0051049 181 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
regulation of cell death GO:0010941 173 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
male gamete generation GO:0048232 201 0.012
wound healing GO:0042060 75 0.012
cell adhesion GO:0007155 136 0.012
positive regulation of molecular function GO:0044093 136 0.012
defense response to other organism GO:0098542 225 0.012
neuron recognition GO:0008038 101 0.012
limb morphogenesis GO:0035108 1 0.012
regulation of sequestering of triglyceride GO:0010889 3 0.012
stem cell differentiation GO:0048863 117 0.012
histolysis GO:0007559 102 0.012
response to nutrient levels GO:0031667 114 0.011
open tracheal system development GO:0007424 204 0.011
gene silencing GO:0016458 138 0.011
water homeostasis GO:0030104 3 0.011
regulation of lipid transport GO:0032368 3 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
protein ubiquitination GO:0016567 70 0.011
leg disc morphogenesis GO:0007478 80 0.011
spinal cord development GO:0021510 1 0.011
ameboidal type cell migration GO:0001667 151 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
imaginal disc derived wing vein specification GO:0007474 48 0.011
cell junction organization GO:0034330 57 0.011
organophosphate catabolic process GO:0046434 112 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
sensory perception of pain GO:0019233 4 0.011
response to endogenous stimulus GO:0009719 119 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
response to other organism GO:0051707 293 0.011
regulation of cellular component size GO:0032535 98 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
cellular macromolecule localization GO:0070727 220 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
asymmetric stem cell division GO:0098722 49 0.011
wing disc pattern formation GO:0035222 66 0.011
growth GO:0040007 359 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
regulation of hydrolase activity GO:0051336 97 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
central nervous system development GO:0007417 201 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
protein maturation GO:0051604 71 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of programmed cell death GO:0043067 152 0.010
negative regulation of gene expression epigenetic GO:0045814 77 0.010
cytokinesis GO:0000910 90 0.010
formation of anatomical boundary GO:0048859 37 0.010
maintenance of location GO:0051235 73 0.010
negative regulation of cell cycle GO:0045786 116 0.010
positive regulation of developmental process GO:0051094 143 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
apoptotic process GO:0006915 159 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
single organism cellular localization GO:1902580 180 0.010
synapse assembly GO:0007416 143 0.010
epithelial cell differentiation GO:0030855 322 0.010
regulation of developmental growth GO:0048638 174 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
phospholipid homeostasis GO:0055091 1 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
reproductive system development GO:0061458 74 0.010
negative regulation of cell death GO:0060548 81 0.010
hemocyte differentiation GO:0042386 38 0.010
response to radiation GO:0009314 155 0.010
single organism intracellular transport GO:1902582 207 0.010
regulation of response to stress GO:0080134 200 0.010
mesenchymal cell differentiation GO:0048762 1 0.010
mrna metabolic process GO:0016071 124 0.010
meiotic nuclear division GO:0007126 151 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
detection of stimulus GO:0051606 156 0.010
positive regulation of programmed cell death GO:0043068 62 0.010
stem cell division GO:0017145 69 0.010
chromatin organization GO:0006325 207 0.010

Bro disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.022
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.017
cancer DOID:162 0 0.017
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.015
sensory system disease DOID:0050155 0 0.013
eye disease DOID:5614 0 0.012
eye and adnexa disease DOID:1492 0 0.012
acquired metabolic disease DOID:0060158 0 0.011
glucose metabolism disease DOID:4194 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
diabetes mellitus DOID:9351 0 0.011
cardiovascular system disease DOID:1287 0 0.011