Drosophila melanogaster

0 known processes

LRP1 (Dmel_CG33087)

LDL receptor protein 1

(Aliases: CG33087,CT9297,lrp1,CG8706,CG30368,LDLR,Dmel\CG33087)

LRP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to abiotic stimulus GO:0009628 341 0.050
cellular catabolic process GO:0044248 372 0.050
vesicle mediated transport GO:0016192 381 0.047
Mouse
small molecule metabolic process GO:0044281 305 0.044
Mouse
endocytosis GO:0006897 310 0.043
Mouse
organelle fission GO:0048285 340 0.041
nuclear division GO:0000280 332 0.040
response to external biotic stimulus GO:0043207 293 0.038
organelle assembly GO:0070925 198 0.037
establishment of localization in cell GO:0051649 402 0.036
imaginal disc derived appendage development GO:0048737 399 0.034
appendage development GO:0048736 401 0.034
imaginal disc derived wing morphogenesis GO:0007476 337 0.033
columnar cuboidal epithelial cell development GO:0002066 249 0.033
death GO:0016265 284 0.033
cellular protein modification process GO:0006464 438 0.032
phagocytosis GO:0006909 215 0.032
Mouse
catabolic process GO:0009056 409 0.032
protein modification process GO:0036211 438 0.032
epithelial cell development GO:0002064 274 0.031
response to other organism GO:0051707 293 0.031
organic substance transport GO:0071702 257 0.030
Mouse
organonitrogen compound metabolic process GO:1901564 318 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.030
organic substance catabolic process GO:1901575 308 0.029
aromatic compound catabolic process GO:0019439 166 0.029
imaginal disc derived appendage morphogenesis GO:0035114 395 0.029
regulation of response to stress GO:0080134 200 0.028
forebrain development GO:0030900 2 0.028
appendage morphogenesis GO:0035107 397 0.028
central nervous system development GO:0007417 201 0.027
morphogenesis of an epithelium GO:0002009 276 0.027
defense response GO:0006952 300 0.027
wing disc morphogenesis GO:0007472 344 0.026
intracellular transport GO:0046907 228 0.026
salivary gland development GO:0007431 162 0.026
response to biotic stimulus GO:0009607 294 0.026
pigment metabolic process GO:0042440 84 0.026
chromosome segregation GO:0007059 157 0.025
response to organic substance GO:0010033 284 0.025
neurological system process GO:0050877 358 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
epithelial cell differentiation GO:0030855 322 0.025
body morphogenesis GO:0010171 2 0.025
single organism biosynthetic process GO:0044711 206 0.024
monocarboxylic acid transport GO:0015718 3 0.024
positive regulation of cell communication GO:0010647 250 0.024
protein transport GO:0015031 155 0.024
ocellus pigment biosynthetic process GO:0008055 19 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
developmental pigmentation GO:0048066 68 0.024
positive regulation of signal transduction GO:0009967 223 0.023
immune response GO:0006955 246 0.023
ovarian follicle cell development GO:0030707 248 0.023
taxis GO:0042330 304 0.022
regulation of catalytic activity GO:0050790 185 0.022
Mouse
organophosphate metabolic process GO:0019637 195 0.022
gland morphogenesis GO:0022612 145 0.022
negative regulation of signal transduction GO:0009968 206 0.022
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.021
exocrine system development GO:0035272 162 0.021
single organism behavior GO:0044708 391 0.021
cell death GO:0008219 279 0.021
cellular response to organic substance GO:0071310 132 0.021
programmed cell death GO:0012501 257 0.021
single organism intracellular transport GO:1902582 207 0.021
response to monosaccharide GO:0034284 4 0.021
defense response to other organism GO:0098542 225 0.021
heterocycle catabolic process GO:0046700 166 0.021
humoral immune response GO:0006959 117 0.020
connective tissue development GO:0061448 3 0.020
regulation of tube size open tracheal system GO:0035151 43 0.020
localization of cell GO:0051674 257 0.020
Mouse
negative regulation of cell communication GO:0010648 223 0.020
Mouse
positive regulation of signaling GO:0023056 243 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
pigmentation GO:0043473 75 0.019
tissue morphogenesis GO:0048729 297 0.019
respiratory system development GO:0060541 213 0.019
developmental growth GO:0048589 280 0.019
response to glucose GO:0009749 2 0.019
gland development GO:0048732 191 0.019
regulation of immune system process GO:0002682 176 0.019
compound eye development GO:0048749 307 0.019
cellular response to hexose stimulus GO:0071331 1 0.019
establishment of protein localization GO:0045184 163 0.019
regulation of localization GO:0032879 275 0.019
Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.018
cellular macromolecule catabolic process GO:0044265 136 0.018
single organism catabolic process GO:0044712 228 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
telencephalon development GO:0021537 2 0.018
developmental maturation GO:0021700 172 0.018
negative regulation of gene expression GO:0010629 387 0.018
proteolysis GO:0006508 192 0.018
pigment biosynthetic process GO:0046148 36 0.018
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
nucleotide metabolic process GO:0009117 161 0.018
cell recognition GO:0008037 102 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
open tracheal system development GO:0007424 204 0.018
innate immune response GO:0045087 144 0.017
regulation of transport GO:0051049 181 0.017
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
Mouse
antimicrobial humoral response GO:0019730 99 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
secondary metabolic process GO:0019748 75 0.017
regulation of nervous system development GO:0051960 248 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
meiotic cell cycle GO:0051321 171 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
single organism cellular localization GO:1902580 180 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
cell motility GO:0048870 251 0.016
Mouse
regulation of cellular amine metabolic process GO:0033238 3 0.016
regulation of cell cycle process GO:0010564 181 0.016
eye development GO:0001654 323 0.016
oxoacid metabolic process GO:0043436 103 0.016
tube development GO:0035295 244 0.016
protein localization GO:0008104 284 0.016
salivary gland morphogenesis GO:0007435 145 0.016
response to lipopolysaccharide GO:0032496 4 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
gtp catabolic process GO:0006184 72 0.016
microtubule based movement GO:0007018 51 0.016
regulation of response to external stimulus GO:0032101 115 0.016
cell projection assembly GO:0030031 94 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
regulation of cell cycle GO:0051726 291 0.016
cellular macromolecule localization GO:0070727 220 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
glycosyl compound catabolic process GO:1901658 112 0.016
eye pigmentation GO:0048069 43 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
immune system process GO:0002376 347 0.016
camera type eye development GO:0043010 4 0.016
eggshell formation GO:0030703 105 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
positive regulation of molecular function GO:0044093 136 0.016
tissue death GO:0016271 102 0.015
developmental programmed cell death GO:0010623 138 0.015
macromolecule catabolic process GO:0009057 161 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
purine containing compound metabolic process GO:0072521 155 0.015
positive regulation of catabolic process GO:0009896 105 0.015
mrna metabolic process GO:0016071 124 0.015
histolysis GO:0007559 102 0.015
regulation of cell death GO:0010941 173 0.015
regulation of immune response GO:0050776 118 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
intracellular protein transport GO:0006886 104 0.015
mushroom body development GO:0016319 70 0.015
meiotic nuclear division GO:0007126 151 0.015
organic acid metabolic process GO:0006082 103 0.015
defense response to bacterium GO:0042742 178 0.015
synapse assembly GO:0007416 143 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.015
chromosome organization GO:0051276 360 0.015
head development GO:0060322 135 0.015
ras protein signal transduction GO:0007265 88 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
spindle organization GO:0007051 253 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
macromolecular complex assembly GO:0065003 256 0.015
purine nucleoside metabolic process GO:0042278 127 0.015
regulation of defense response GO:0031347 102 0.015
eye morphogenesis GO:0048592 260 0.015
tissue migration GO:0090130 155 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
protein complex biogenesis GO:0070271 201 0.015
somatic muscle development GO:0007525 66 0.015
nucleoside metabolic process GO:0009116 127 0.015
negative regulation of developmental process GO:0051093 201 0.014
growth GO:0040007 359 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
compound eye morphogenesis GO:0001745 249 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
regulation of multi organism process GO:0043900 131 0.014
gtp metabolic process GO:0046039 72 0.014
ocellus pigmentation GO:0033060 19 0.014
response to hexose GO:0009746 3 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
Mouse
ribonucleotide metabolic process GO:0009259 145 0.014
nucleotide catabolic process GO:0009166 109 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
chorion containing eggshell formation GO:0007304 105 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
cell division GO:0051301 248 0.014
gene silencing GO:0016458 138 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
positive regulation of cell motility GO:2000147 3 0.014
response to oxygen containing compound GO:1901700 200 0.014
regulation of molecular function GO:0065009 217 0.014
Mouse
regulation of synapse structure and activity GO:0050803 128 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
limb development GO:0060173 1 0.014
response to bacterium GO:0009617 198 0.014
protein complex assembly GO:0006461 200 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
phosphorylation GO:0016310 294 0.013
regulation of protein metabolic process GO:0051246 256 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
lateral inhibition GO:0046331 206 0.013
spinal cord development GO:0021510 1 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
mesenchymal cell differentiation GO:0048762 1 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
ion transport GO:0006811 145 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
negative regulation of signaling GO:0023057 219 0.013
Mouse
ommochrome biosynthetic process GO:0006727 19 0.013
axis specification GO:0009798 167 0.013
biological adhesion GO:0022610 138 0.013
sensory organ morphogenesis GO:0090596 260 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
anatomical structure homeostasis GO:0060249 97 0.013
digestive tract morphogenesis GO:0048546 127 0.013
regulation of organelle organization GO:0033043 196 0.013
Mouse
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
intracellular signal transduction GO:0035556 300 0.013
tube morphogenesis GO:0035239 191 0.013
muscle structure development GO:0061061 224 0.013
cellular amine metabolic process GO:0044106 12 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
dendrite development GO:0016358 204 0.013
embryonic pattern specification GO:0009880 174 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
regulation of cellular localization GO:0060341 136 0.013
response to extracellular stimulus GO:0009991 116 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
regulation of synapse assembly GO:0051963 94 0.012
mesenchymal cell development GO:0014031 1 0.012
eye pigment metabolic process GO:0042441 33 0.012
positive regulation of cell migration GO:0030335 2 0.012
immune response activating signal transduction GO:0002757 2 0.012
cytoplasmic transport GO:0016482 130 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
regulation of cell differentiation GO:0045595 302 0.012
cellular amide metabolic process GO:0043603 80 0.012
regulation of apoptotic process GO:0042981 130 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
regulation of humoral immune response GO:0002920 51 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
regulation of catabolic process GO:0009894 170 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
production of molecular mediator of immune response GO:0002440 46 0.012
chemosensory behavior GO:0007635 106 0.012
pigment metabolic process involved in pigmentation GO:0043474 33 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
amine metabolic process GO:0009308 12 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
salivary gland histolysis GO:0035070 88 0.012
homeostatic process GO:0042592 199 0.012
response to organophosphorus GO:0046683 2 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
hindbrain development GO:0030902 2 0.012
cell cycle phase transition GO:0044770 140 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
apoptotic process GO:0006915 159 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
regulation of programmed cell death GO:0043067 152 0.012
transmembrane transport GO:0055085 139 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
inter male aggressive behavior GO:0002121 60 0.012
cell maturation GO:0048469 144 0.012
regulation of innate immune response GO:0045088 71 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
cell proliferation GO:0008283 299 0.012
cellular protein localization GO:0034613 160 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
negative regulation of growth GO:0045926 84 0.012
kidney development GO:0001822 3 0.012
sensory perception GO:0007600 196 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
organophosphate catabolic process GO:0046434 112 0.011
membrane organization GO:0061024 112 0.011
chemotaxis GO:0006935 249 0.011
ameboidal type cell migration GO:0001667 151 0.011
synapse organization GO:0050808 196 0.011
segmentation GO:0035282 207 0.011
regionalization GO:0003002 416 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.011
regulation of cell development GO:0060284 215 0.011
embryonic morphogenesis GO:0048598 206 0.011
rna splicing GO:0008380 83 0.011
secondary metabolite biosynthetic process GO:0044550 24 0.011
meiotic cell cycle process GO:1903046 132 0.011
actin filament based process GO:0030029 220 0.011
Mouse
negative regulation of multicellular organismal process GO:0051241 142 0.011
blastoderm segmentation GO:0007350 159 0.011
activation of innate immune response GO:0002218 4 0.011
secretion by cell GO:0032940 101 0.011
secretion GO:0046903 109 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
multi organism behavior GO:0051705 175 0.011
dorsal ventral axis specification GO:0009950 66 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.011
response to starvation GO:0042594 97 0.011
endomembrane system organization GO:0010256 119 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
mitotic nuclear division GO:0007067 213 0.011
rna processing GO:0006396 147 0.011
regulation of cell proliferation GO:0042127 163 0.011
cilium organization GO:0044782 41 0.011
synaptic target recognition GO:0008039 45 0.011
cell adhesion GO:0007155 136 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
cilium assembly GO:0042384 38 0.011
mitotic spindle organization GO:0007052 220 0.011
detection of stimulus involved in sensory perception GO:0050906 92 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
regulation of intracellular protein transport GO:0033157 46 0.011
cellular lipid metabolic process GO:0044255 83 0.011
positive regulation of transport GO:0051050 92 0.011
Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
response to temperature stimulus GO:0009266 106 0.011
cellular response to monosaccharide stimulus GO:0071326 2 0.011
mrna processing GO:0006397 104 0.011
regulation of tube architecture open tracheal system GO:0035152 68 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
regulation of immune effector process GO:0002697 52 0.010
purine containing compound catabolic process GO:0072523 112 0.010
ommatidial rotation GO:0016318 20 0.010
regulation of anatomical structure size GO:0090066 163 0.010
transcription from rna polymerase ii promoter GO:0006366 368 0.010
dendrite morphogenesis GO:0048813 199 0.010
positive regulation of developmental process GO:0051094 143 0.010
protein phosphorylation GO:0006468 169 0.010
nitrogen compound transport GO:0071705 85 0.010
immune response regulating signaling pathway GO:0002764 2 0.010
response to radiation GO:0009314 155 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
mitotic cytokinesis GO:0000281 50 0.010
cellular ketone metabolic process GO:0042180 24 0.010
ommochrome metabolic process GO:0046152 19 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
cellular protein catabolic process GO:0044257 83 0.010
chromatin organization GO:0006325 207 0.010
cholesterol transport GO:0030301 2 0.010
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.010
autophagy GO:0006914 108 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
ocellus pigment metabolic process GO:0046158 19 0.010
response to nitrogen compound GO:1901698 90 0.010
response to endogenous stimulus GO:0009719 119 0.010

LRP1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
inherited metabolic disorder DOID:655 0 0.011