Drosophila melanogaster

154 known processes

mus309 (Dmel_CG6920)

mutagen-sensitive 309

(Aliases: mus 309,blm,Dmblm,DmKu70,CG6920,Dmel\CG6920,Blm,MUS309,Ku70,DmBlm,RecQ,mus309/DmBLM,DmBLM)

mus309 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair via nonhomologous end joining GO:0006303 5 0.869
non recombinational repair GO:0000726 7 0.819
double strand break repair GO:0006302 26 0.727
mitotic g2 m transition checkpoint GO:0044818 70 0.688
Human
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.649
g2 dna damage checkpoint GO:0031572 69 0.593
Human
cell division GO:0051301 248 0.575
Human
nucleobase containing compound catabolic process GO:0034655 165 0.514
negative regulation of cell cycle GO:0045786 116 0.437
Human
negative regulation of cell cycle phase transition GO:1901988 103 0.435
Human
dna synthesis involved in dna repair GO:0000731 5 0.359
mitotic g2 dna damage checkpoint GO:0007095 69 0.322
Human
negative regulation of cell cycle g2 m phase transition GO:1902750 8 0.289
negative regulation of cell cycle process GO:0010948 109 0.273
Human
mitotic dna damage checkpoint GO:0044773 74 0.271
Human
dna integrity checkpoint GO:0031570 81 0.257
Human Worm
meiosis i GO:0007127 59 0.241
regulation of cell cycle phase transition GO:1901987 130 0.237
Human
negative regulation of mitotic cell cycle GO:0045930 109 0.235
Human
meiotic cell cycle process GO:1903046 132 0.221
dna repair GO:0006281 54 0.207
double strand break repair via homologous recombination GO:0000724 13 0.191
meiotic chromosome segregation GO:0045132 59 0.189
Worm
mitotic dna integrity checkpoint GO:0044774 75 0.176
Human
dna recombination GO:0006310 32 0.174
organic cyclic compound catabolic process GO:1901361 168 0.172
cellular catabolic process GO:0044248 372 0.171
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.169
response to abiotic stimulus GO:0009628 341 0.167
Human Worm
cellular response to dna damage stimulus GO:0006974 223 0.159
female meiotic division GO:0007143 70 0.159
death GO:0016265 284 0.157
Mouse Worm
catabolic process GO:0009056 409 0.151
dna double strand break processing GO:0000729 3 0.150
Human
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 8 0.145
regulation of dna repair GO:0006282 5 0.143
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.138
aromatic compound catabolic process GO:0019439 166 0.134
regulation of cell differentiation GO:0045595 302 0.133
positive regulation of macromolecule metabolic process GO:0010604 405 0.133
Human
negative regulation of cellular biosynthetic process GO:0031327 277 0.132
cell cycle phase transition GO:0044770 140 0.126
Human
cellular nitrogen compound catabolic process GO:0044270 165 0.124
dna damage checkpoint GO:0000077 78 0.119
Human Worm
regulation of cell cycle GO:0051726 291 0.110
Human
regulation of multicellular organismal development GO:2000026 414 0.110
positive regulation of transcription dna templated GO:0045893 266 0.106
Human
regulation of cellular protein metabolic process GO:0032268 243 0.106
Human
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.102
Human
reciprocal dna recombination GO:0035825 19 0.099
mrna metabolic process GO:0016071 124 0.099
mrna processing GO:0006397 104 0.096
response to organic substance GO:0010033 284 0.095
Human
macromolecule catabolic process GO:0009057 161 0.093
Human
mitotic recombination GO:0006312 2 0.089
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.088
Human
regulation of cell cycle process GO:0010564 181 0.086
Human
response to ionizing radiation GO:0010212 32 0.086
Human Worm
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.085
Human
nuclear transcribed mrna catabolic process GO:0000956 24 0.084
positive regulation of rna biosynthetic process GO:1902680 266 0.083
Human
mitotic cell cycle checkpoint GO:0007093 88 0.082
Human
small molecule metabolic process GO:0044281 305 0.080
positive regulation of rna metabolic process GO:0051254 271 0.078
Human
regulation of protein metabolic process GO:0051246 256 0.078
Human
asymmetric cell division GO:0008356 37 0.077
response to alkaloid GO:0043279 26 0.075
Human
translesion synthesis GO:0019985 2 0.072
cell cycle checkpoint GO:0000075 95 0.072
Human Worm
telomere maintenance via recombination GO:0000722 1 0.071
response to radiation GO:0009314 155 0.069
Human Worm
regulation of mitotic cell cycle phase transition GO:1901990 130 0.068
Human
positive regulation of biosynthetic process GO:0009891 316 0.068
Human
regulation of mitotic cell cycle GO:0007346 190 0.068
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.068
nucleotide excision repair GO:0006289 8 0.067
recombinational repair GO:0000725 13 0.067
regulation of double strand break repair GO:2000779 3 0.064
chromosome segregation GO:0007059 157 0.064
Worm
postreplication repair GO:0006301 2 0.064
rna processing GO:0006396 147 0.064
regulation of embryonic development GO:0045995 68 0.063
rna catabolic process GO:0006401 37 0.062
mitotic cell cycle phase transition GO:0044772 138 0.060
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.059
organelle fission GO:0048285 340 0.059
protein modification process GO:0036211 438 0.058
Human
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.055
protein complex assembly GO:0006461 200 0.055
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.055
positive regulation of cellular biosynthetic process GO:0031328 316 0.055
Human
positive regulation of catabolic process GO:0009896 105 0.055
cellular response to abiotic stimulus GO:0071214 58 0.055
Human
cellular protein modification process GO:0006464 438 0.054
Human
female meiosis chromosome segregation GO:0016321 33 0.053
retina development in camera type eye GO:0060041 4 0.053
organic substance catabolic process GO:1901575 308 0.053
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.052
Human
programmed cell death GO:0012501 257 0.051
Mouse Worm
positive regulation of nucleic acid templated transcription GO:1903508 266 0.050
Human
nucleobase containing small molecule metabolic process GO:0055086 174 0.049
macromolecular complex assembly GO:0065003 256 0.049
Human
regulation of cell development GO:0060284 215 0.048
mrna catabolic process GO:0006402 33 0.048
response to monosaccharide GO:0034284 4 0.046
single organism biosynthetic process GO:0044711 206 0.045
regulation of nervous system development GO:0051960 248 0.044
transmembrane transport GO:0055085 139 0.044
purine nucleoside metabolic process GO:0042278 127 0.043
organonitrogen compound metabolic process GO:1901564 318 0.043
positive regulation of nervous system development GO:0051962 69 0.043
organophosphate metabolic process GO:0019637 195 0.043
anatomical structure homeostasis GO:0060249 97 0.042
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.042
maintenance of location GO:0051235 73 0.042
ribonucleoside monophosphate catabolic process GO:0009158 39 0.041
telomere organization GO:0032200 21 0.041
Mouse
homeostatic process GO:0042592 199 0.041
Mouse
camera type eye development GO:0043010 4 0.040
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.040
g2 m transition of mitotic cell cycle GO:0000086 19 0.040
purine containing compound catabolic process GO:0072523 112 0.040
ribonucleoside triphosphate metabolic process GO:0009199 119 0.039
carboxylic acid metabolic process GO:0019752 92 0.039
posttranscriptional regulation of gene expression GO:0010608 145 0.039
humoral immune response GO:0006959 117 0.038
heterocycle catabolic process GO:0046700 166 0.038
positive regulation of cellular catabolic process GO:0031331 95 0.037
retrograde axon cargo transport GO:0008090 9 0.037
protein phosphorylation GO:0006468 169 0.036
Human
response to anesthetic GO:0072347 9 0.036
dorsal ventral pattern formation GO:0009953 133 0.036
negative regulation of biosynthetic process GO:0009890 277 0.036
chromosome organization GO:0051276 360 0.035
Mouse Worm
long term memory GO:0007616 62 0.035
cell cycle g2 m phase transition GO:0044839 22 0.034
positive regulation of developmental process GO:0051094 143 0.034
positive regulation of cell communication GO:0010647 250 0.034
positive regulation of multicellular organismal process GO:0051240 143 0.033
organic acid metabolic process GO:0006082 103 0.033
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.033
purine ribonucleoside metabolic process GO:0046128 127 0.033
negative regulation of gene expression GO:0010629 387 0.033
regulation of meiosis GO:0040020 3 0.033
mrna 3 end processing GO:0031124 28 0.033
ribose phosphate metabolic process GO:0019693 145 0.032
apoptotic process GO:0006915 159 0.032
Mouse Worm
negative regulation of response to stimulus GO:0048585 258 0.032
positive regulation of endopeptidase activity GO:0010950 26 0.032
oxoacid metabolic process GO:0043436 103 0.032
endocytosis GO:0006897 310 0.031
molting cycle chitin based cuticle GO:0007591 56 0.031
cell proliferation GO:0008283 299 0.031
Mouse
positive regulation of signaling GO:0023056 243 0.031
regulation of transport GO:0051049 181 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
ion transport GO:0006811 145 0.030
regulation of neurogenesis GO:0050767 158 0.030
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.030
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.030
kidney morphogenesis GO:0060993 3 0.029
nucleoside metabolic process GO:0009116 127 0.029
negative regulation of cell division GO:0051782 17 0.029
Human
response to caffeine GO:0031000 12 0.028
regionalization GO:0003002 416 0.028
response to drug GO:0042493 17 0.028
sensory organ morphogenesis GO:0090596 260 0.028
reciprocal meiotic recombination GO:0007131 19 0.028
lipid storage GO:0019915 38 0.027
ribonucleoside catabolic process GO:0042454 112 0.027
dna biosynthetic process GO:0071897 24 0.027
phosphorylation GO:0016310 294 0.027
Human
regulation of dna recombination GO:0000018 4 0.026
Human Mouse
signal transduction in response to dna damage GO:0042770 3 0.026
epithelial cell development GO:0002064 274 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
telomere maintenance GO:0000723 21 0.026
Mouse
positive regulation of signal transduction GO:0009967 223 0.026
meiotic cell cycle GO:0051321 171 0.026
cellular response to radiation GO:0071478 52 0.026
Human
regulation of cell death GO:0010941 173 0.026
Mouse Worm
negative regulation of signal transduction GO:0009968 206 0.026
regulation of intracellular signal transduction GO:1902531 236 0.026
regulation of cell division GO:0051302 72 0.025
Human
vesicle mediated transport GO:0016192 381 0.025
mitotic cell cycle embryonic GO:0045448 38 0.025
cell death GO:0008219 279 0.025
Mouse Worm
cellular amino acid metabolic process GO:0006520 61 0.025
regulation of cellular response to stress GO:0080135 89 0.025
cellular response to chemical stimulus GO:0070887 199 0.025
Human
negative regulation of cell communication GO:0010648 223 0.025
cellular macromolecule catabolic process GO:0044265 136 0.024
Human
regulation of epithelial cell differentiation GO:0030856 4 0.024
organonitrogen compound catabolic process GO:1901565 128 0.024
metal ion transport GO:0030001 74 0.023
cellular macromolecular complex assembly GO:0034622 153 0.023
meiotic nuclear division GO:0007126 151 0.023
digestive tract development GO:0048565 149 0.023
purine nucleotide metabolic process GO:0006163 146 0.022
regulation of localization GO:0032879 275 0.022
purine containing compound metabolic process GO:0072521 155 0.022
immune system process GO:0002376 347 0.022
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.022
male gamete generation GO:0048232 201 0.021
dorsal ventral axis specification GO:0009950 66 0.021
atp metabolic process GO:0046034 49 0.021
compound eye morphogenesis GO:0001745 249 0.021
body morphogenesis GO:0010171 2 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.021
positive regulation of catalytic activity GO:0043085 118 0.021
regulation of catalytic activity GO:0050790 185 0.021
Human
regulation of cellular catabolic process GO:0031329 157 0.021
rna localization GO:0006403 115 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
dna geometric change GO:0032392 16 0.020
regulation of organelle organization GO:0033043 196 0.020
cellular amine metabolic process GO:0044106 12 0.020
positive regulation of epithelial cell differentiation GO:0030858 1 0.020
negative regulation of multicellular organismal process GO:0051241 142 0.020
regulation of peptidase activity GO:0052547 39 0.020
positive regulation of intracellular signal transduction GO:1902533 116 0.020
regulation of multi organism process GO:0043900 131 0.020
gastrulation GO:0007369 70 0.019
positive regulation of cell differentiation GO:0045597 64 0.019
positive regulation of protein metabolic process GO:0051247 128 0.019
regulation of mrna metabolic process GO:1903311 72 0.019
cytokinesis GO:0000910 90 0.019
male meiosis chromosome segregation GO:0007060 10 0.019
response to oxygen containing compound GO:1901700 200 0.019
Human
positive regulation of gene expression GO:0010628 290 0.019
Human
regulation of hydrolase activity GO:0051336 97 0.019
stress activated mapk cascade GO:0051403 52 0.018
negative regulation of cell differentiation GO:0045596 143 0.018
secretion GO:0046903 109 0.018
response to other organism GO:0051707 293 0.018
purine nucleoside catabolic process GO:0006152 112 0.018
eye development GO:0001654 323 0.018
germarium derived oocyte fate determination GO:0007294 26 0.018
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
spermatogenesis GO:0007283 200 0.017
cellular response to ionizing radiation GO:0071479 15 0.017
Human
synaptic transmission GO:0007268 288 0.017
lipid localization GO:0010876 54 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
regulation of organ morphogenesis GO:2000027 78 0.017
regulation of nuclear division GO:0051783 58 0.017
positive regulation of cell size GO:0045793 21 0.017
positive regulation of apoptotic process GO:0043065 47 0.016
catechol containing compound biosynthetic process GO:0009713 3 0.016
mrna splicing via spliceosome GO:0000398 73 0.016
posttranscriptional gene silencing by rna GO:0035194 45 0.016
mitotic dna replication checkpoint GO:0033314 5 0.016
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.016
negative regulation of cell proliferation GO:0008285 69 0.016
rna 3 end processing GO:0031123 45 0.016
actin filament based process GO:0030029 220 0.016
ribonucleoside triphosphate catabolic process GO:0009203 108 0.016
protein localization GO:0008104 284 0.016
organophosphate catabolic process GO:0046434 112 0.016
response to organonitrogen compound GO:0010243 75 0.016
Human
positive regulation of neurogenesis GO:0050769 41 0.016
amine metabolic process GO:0009308 12 0.016
regulation of synaptic transmission GO:0050804 69 0.016
negative regulation of signaling GO:0023057 219 0.016
carbohydrate metabolic process GO:0005975 82 0.016
regulation of cysteine type endopeptidase activity GO:2000116 27 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.015
ion transmembrane transport GO:0034220 122 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
Human
establishment of localization in cell GO:0051649 402 0.015
organelle assembly GO:0070925 198 0.015
positive regulation of proteolysis GO:0045862 52 0.015
regulation of mrna catabolic process GO:0061013 5 0.015
negative regulation of translation GO:0017148 28 0.015
positive regulation of peptidase activity GO:0010952 29 0.015
alternative mrna splicing via spliceosome GO:0000380 60 0.015
regulation of mrna processing GO:0050684 71 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
anion transmembrane transport GO:0098656 26 0.014
alpha amino acid metabolic process GO:1901605 20 0.014
regulation of anatomical structure size GO:0090066 163 0.014
regulation of autophagy GO:0010506 62 0.014
cell aging GO:0007569 2 0.014
organic substance transport GO:0071702 257 0.014
negative regulation of nervous system development GO:0051961 92 0.014
oocyte fate determination GO:0030716 27 0.014
nuclear division GO:0000280 332 0.014
regulation of response to dna damage stimulus GO:2001020 23 0.014
regulation of apoptotic process GO:0042981 130 0.014
Mouse Worm
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
regulation of response to biotic stimulus GO:0002831 63 0.013
intracellular mrna localization GO:0008298 66 0.013
cellular response to mechanical stimulus GO:0071260 2 0.013
jnk cascade GO:0007254 50 0.013
regulation of pole plasm oskar mrna localization GO:0007317 27 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
regulation of cell maturation GO:1903429 27 0.013
cellular response to gamma radiation GO:0071480 10 0.013
forebrain development GO:0030900 2 0.013
negative regulation of developmental growth GO:0048640 64 0.013
antimicrobial humoral response GO:0019730 99 0.013
regulation of g2 m transition of mitotic cell cycle GO:0010389 15 0.013
purine nucleoside monophosphate catabolic process GO:0009128 38 0.013
regulation of endopeptidase activity GO:0052548 36 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
dna metabolic process GO:0006259 227 0.013
regulation of cell proliferation GO:0042127 163 0.012
Mouse
regulation of stress activated mapk cascade GO:0032872 41 0.012
single organism behavior GO:0044708 391 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
nitrogen compound transport GO:0071705 85 0.012
response to oxidative stress GO:0006979 86 0.012
developmental growth GO:0048589 280 0.012
regulation of protein complex assembly GO:0043254 42 0.012
response to nitrogen compound GO:1901698 90 0.012
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
protein catabolic process GO:0030163 101 0.012
regulation of oocyte development GO:0060281 27 0.012
regulation of rna splicing GO:0043484 69 0.012
regulation of catabolic process GO:0009894 170 0.012
regulation of nf kappab import into nucleus GO:0042345 1 0.012
response to ethanol GO:0045471 59 0.012
male meiosis cytokinesis GO:0007112 26 0.012
cellular homeostasis GO:0019725 80 0.012
regulation of phosphorylation GO:0042325 147 0.011
Human
production of molecular mediator of immune response GO:0002440 46 0.011
primary amino compound metabolic process GO:1901160 2 0.011
cellular response to organic substance GO:0071310 132 0.011
Human
regulation of protein modification process GO:0031399 112 0.011
Human
purine ribonucleotide metabolic process GO:0009150 145 0.011
regulation of cellular component size GO:0032535 98 0.011
rna splicing GO:0008380 83 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
negative regulation of developmental process GO:0051093 201 0.011
regulation of jnk cascade GO:0046328 40 0.011
positive regulation of molecular function GO:0044093 136 0.011
learning or memory GO:0007611 141 0.011
epithelial cell differentiation GO:0030855 322 0.011
nucleotide metabolic process GO:0009117 161 0.011
autophagy GO:0006914 108 0.011
appendage morphogenesis GO:0035107 397 0.011
cellular protein complex assembly GO:0043623 71 0.011
wnt signaling pathway GO:0016055 98 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
response to paraquat GO:1901562 4 0.011
response to light stimulus GO:0009416 124 0.011
dorsal closure GO:0007391 79 0.011
response to decreased oxygen levels GO:0036293 58 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
mesenchymal cell development GO:0014031 1 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
negative regulation of growth GO:0045926 84 0.011
cellular macromolecule localization GO:0070727 220 0.011
regulation of molecular function GO:0065009 217 0.011
Human Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.010
cation transport GO:0006812 110 0.010
anterior posterior axis specification GO:0009948 109 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.010
regulation of photoreceptor cell differentiation GO:0046532 34 0.010
cell motility GO:0048870 251 0.010
regulation of ion transport GO:0043269 39 0.010
polarity specification of dorsal ventral axis GO:0009951 6 0.010
actin cytoskeleton organization GO:0030036 206 0.010
regulation of mrna 3 end processing GO:0031440 7 0.010
stress activated protein kinase signaling cascade GO:0031098 55 0.010
response to hypoxia GO:0001666 53 0.010
response to external biotic stimulus GO:0043207 293 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
negative regulation of meiotic cell cycle GO:0051447 2 0.010
cuticle development GO:0042335 86 0.010

mus309 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.046
disease of cellular proliferation DOID:14566 0 0.046
thoracic cancer DOID:5093 0 0.041
organ system cancer DOID:0050686 0 0.041
disease of anatomical entity DOID:7 0 0.016
breast cancer DOID:1612 0 0.015
bone disease DOID:0080001 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
male reproductive organ cancer DOID:3856 0 0.011
reproductive organ cancer DOID:193 0 0.011