Drosophila melanogaster

225 known processes

btl (Dmel_CG32134)

breathless

(Aliases: CG32134,DFGF-R1,DmHD-311,HD-311,BTL/FGFR2,Fgf-r,CT20816,D-FGFR,0844/01,Tk2,FGFR1,FGFR,Dtk2,fgf-r,dFGFR,DFR2,Dmel\CG32134,dtk2,l(3)00208,Dfr-2,dev,lambdatop,Btl,CG6714)

btl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
branching involved in open tracheal system development GO:0060446 45 1.000
open tracheal system development GO:0007424 204 1.000
respiratory system development GO:0060541 213 1.000
morphogenesis of a branching epithelium GO:0061138 45 0.996
trachea morphogenesis GO:0060439 22 0.990
tube morphogenesis GO:0035239 191 0.982
morphogenesis of an epithelium GO:0002009 276 0.980
terminal branching open tracheal system GO:0007430 17 0.978
branching morphogenesis of an epithelial tube GO:0048754 45 0.978
tube development GO:0035295 244 0.969
epithelial cell migration open tracheal system GO:0007427 32 0.951
tissue morphogenesis GO:0048729 297 0.948
trachea development GO:0060438 29 0.942
eye development GO:0001654 323 0.903
Mouse
regulation of tube architecture open tracheal system GO:0035152 68 0.890
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.886
embryonic hindgut morphogenesis GO:0048619 48 0.883
regulation of anatomical structure morphogenesis GO:0022603 242 0.871
negative regulation of transcription dna templated GO:0045892 237 0.869
Mouse
regulation of growth GO:0040008 233 0.868
epithelial tube morphogenesis GO:0060562 88 0.858
transcription from rna polymerase ii promoter GO:0006366 368 0.853
Mouse Rat
tissue migration GO:0090130 155 0.846
morphogenesis of a branching structure GO:0001763 45 0.787
axon guidance GO:0007411 233 0.782
Worm
renal system development GO:0072001 72 0.780
Mouse Fly
epithelial cell migration GO:0010631 148 0.746
cellular component assembly involved in morphogenesis GO:0010927 151 0.711
Zebrafish
negative regulation of cellular metabolic process GO:0031324 382 0.673
Mouse
muscle cell differentiation GO:0042692 103 0.666
Mouse Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.654
sensory organ morphogenesis GO:0090596 260 0.650
Mouse
cell projection assembly GO:0030031 94 0.643
malpighian tubule morphogenesis GO:0007443 44 0.630
axonogenesis GO:0007409 290 0.616
cell motility GO:0048870 251 0.605
negative regulation of rna metabolic process GO:0051253 251 0.601
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.596
Mouse
regulation of tube length open tracheal system GO:0035159 24 0.595
blastoderm segmentation GO:0007350 159 0.594
developmental growth GO:0048589 280 0.588
hindgut development GO:0061525 58 0.585
synapse organization GO:0050808 196 0.572
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.566
Mouse
taxis GO:0042330 304 0.555
Worm
negative regulation of gene expression GO:0010629 387 0.552
Mouse
epithelium migration GO:0090132 148 0.550
regulation of multicellular organismal development GO:2000026 414 0.547
branch fusion open tracheal system GO:0035147 17 0.543
neuron projection guidance GO:0097485 241 0.529
Worm
gliogenesis GO:0042063 80 0.521
digestive tract development GO:0048565 149 0.511
Zebrafish Mouse Rat Worm Fly
eye photoreceptor cell differentiation GO:0001754 145 0.509
regulation of developmental growth GO:0048638 174 0.503
regulation of cell development GO:0060284 215 0.487
embryonic pattern specification GO:0009880 174 0.487
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.478
Mouse Rat
negative regulation of cellular biosynthetic process GO:0031327 277 0.463
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.461
Human Zebrafish Mouse Rat Worm
regulation of cell morphogenesis GO:0022604 163 0.460
compound eye development GO:0048749 307 0.456
growth GO:0040007 359 0.452
embryonic morphogenesis GO:0048598 206 0.451
Human Zebrafish Mouse Rat Fly
ameboidal type cell migration GO:0001667 151 0.447
tracheal outgrowth open tracheal system GO:0007426 18 0.440
head development GO:0060322 135 0.429
Zebrafish Mouse Rat
compound eye photoreceptor cell differentiation GO:0001751 140 0.428
regulation of protein metabolic process GO:0051246 256 0.413
response to organic substance GO:0010033 284 0.412
Human Zebrafish Mouse Rat Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.411
Mouse Rat
hindgut morphogenesis GO:0007442 58 0.403
brain development GO:0007420 120 0.402
Zebrafish Mouse Rat
urogenital system development GO:0001655 72 0.401
Mouse Fly
cell division GO:0051301 248 0.400
Mouse
cell proliferation GO:0008283 299 0.400
Human Zebrafish Mouse Rat
photoreceptor cell differentiation GO:0046530 170 0.397
filopodium assembly GO:0046847 33 0.396
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.396
Human Mouse Rat
regulation of cell proliferation GO:0042127 163 0.394
Human Mouse Rat
renal tubule development GO:0061326 64 0.394
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.391
Mouse
cellular response to organic substance GO:0071310 132 0.387
Human Zebrafish Mouse Rat Worm
chemotaxis GO:0006935 249 0.381
Worm
central nervous system development GO:0007417 201 0.381
Zebrafish Mouse Rat Fly
cellular response to growth factor stimulus GO:0071363 30 0.379
Human Zebrafish Mouse Rat Worm
cell fate specification GO:0001708 71 0.376
cell maturation GO:0048469 144 0.372
Mouse
apoptotic process involved in development GO:1902742 20 0.368
positive regulation of biosynthetic process GO:0009891 316 0.367
Human Mouse Rat
regulation of axon extension involved in axon guidance GO:0048841 4 0.365
positive regulation of macromolecule metabolic process GO:0010604 405 0.360
camera type eye development GO:0043010 4 0.359
Mouse
compound eye morphogenesis GO:0001745 249 0.354
enzyme linked receptor protein signaling pathway GO:0007167 179 0.347
Human Zebrafish Mouse Rat Worm
morphogenesis of embryonic epithelium GO:0016331 94 0.344
Mouse
negative regulation of signaling GO:0023057 219 0.337
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.327
Human Mouse Rat
eye morphogenesis GO:0048592 260 0.326
Mouse
amino sugar metabolic process GO:0006040 10 0.326
cell migration GO:0016477 238 0.325
regulation of cellular component size GO:0032535 98 0.324
immune system process GO:0002376 347 0.320
Mouse Fly
cuticle development GO:0042335 86 0.319
response to alcohol GO:0097305 95 0.311
epithelial cell differentiation GO:0030855 322 0.310
spiracle morphogenesis open tracheal system GO:0035277 22 0.308
positive regulation of transcription dna templated GO:0045893 266 0.305
Mouse Rat
mesoderm development GO:0007498 78 0.298
Zebrafish Mouse Rat Fly
ovarian follicle cell development GO:0030707 248 0.297
axon development GO:0061564 297 0.293
regulation of cell projection organization GO:0031344 92 0.292
renal tubule morphogenesis GO:0061333 44 0.290
positive regulation of cellular component organization GO:0051130 156 0.288
Mouse Rat
imaginal disc derived appendage development GO:0048737 399 0.284
positive regulation of nucleic acid templated transcription GO:1903508 266 0.280
Mouse Rat
regulation of tube diameter open tracheal system GO:0035158 11 0.279
segmentation GO:0035282 207 0.268
negative regulation of rna biosynthetic process GO:1902679 240 0.266
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.259
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.258
Mouse Rat
kidney development GO:0001822 3 0.258
Mouse
negative regulation of signal transduction GO:0009968 206 0.258
Mouse
stem cell division GO:0017145 69 0.257
Mouse
apoptotic process GO:0006915 159 0.255
Human Mouse
cellular response to endogenous stimulus GO:0071495 80 0.252
Human Zebrafish Mouse Rat Worm
negative regulation of immune system process GO:0002683 50 0.248
cellular response to chemical stimulus GO:0070887 199 0.247
Human Zebrafish Mouse Rat Worm
developmental maturation GO:0021700 172 0.244
Mouse
eye photoreceptor cell fate commitment GO:0042706 37 0.239
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.237
regulation of cell growth GO:0001558 43 0.236
regulation of localization GO:0032879 275 0.235
forebrain development GO:0030900 2 0.234
Mouse Rat
regulation of cell differentiation GO:0045595 302 0.233
torso signaling pathway GO:0008293 21 0.231
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.230
actin filament organization GO:0007015 126 0.229
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.228
Human Mouse Rat
negative regulation of nucleic acid templated transcription GO:1903507 240 0.226
Mouse
muscle structure development GO:0061061 224 0.223
Mouse Worm Fly
negative regulation of cell communication GO:0010648 223 0.223
Mouse
response to abiotic stimulus GO:0009628 341 0.216
malpighian tubule development GO:0072002 64 0.214
localization of cell GO:0051674 257 0.213
protein modification process GO:0036211 438 0.209
regulation of tube size open tracheal system GO:0035151 43 0.208
appendage development GO:0048736 401 0.199
Mouse
regulation of immune system process GO:0002682 176 0.198
Fly
regulation of cellular protein metabolic process GO:0032268 243 0.198
embryo development ending in birth or egg hatching GO:0009792 152 0.198
Human Mouse Worm
regulation of neuron differentiation GO:0045664 103 0.193
intracellular signal transduction GO:0035556 300 0.189
dna metabolic process GO:0006259 227 0.183
Human
regulation of organelle organization GO:0033043 196 0.183
Mouse
embryonic axis specification GO:0000578 107 0.180
appendage morphogenesis GO:0035107 397 0.179
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.176
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.175
regulation of nervous system development GO:0051960 248 0.175
single organism intracellular transport GO:1902582 207 0.175
positive regulation of phosphate metabolic process GO:0045937 139 0.173
epithelial cell development GO:0002064 274 0.172
positive regulation of rna biosynthetic process GO:1902680 266 0.172
Mouse Rat
establishment or maintenance of cell polarity GO:0007163 167 0.170
imaginal disc derived appendage morphogenesis GO:0035114 395 0.170
imaginal disc derived wing vein specification GO:0007474 48 0.170
salivary gland morphogenesis GO:0007435 145 0.170
Mouse
digestive system development GO:0055123 149 0.168
Zebrafish Mouse Rat Worm Fly
axis specification GO:0009798 167 0.167
regulation of peptidase activity GO:0052547 39 0.158
epithelial cell type specification open tracheal system GO:0035153 11 0.158
protein localization GO:0008104 284 0.157
regulation of neurogenesis GO:0050767 158 0.156
regulation of behavior GO:0050795 75 0.156
secretion by cell GO:0032940 101 0.156
Worm
negative regulation of cell death GO:0060548 81 0.155
Mouse
response to endogenous stimulus GO:0009719 119 0.154
Human Zebrafish Mouse Rat Worm
positive regulation of multicellular organismal process GO:0051240 143 0.151
Human Mouse Rat
anterior posterior pattern specification GO:0009952 136 0.150
protein transport GO:0015031 155 0.150
larval development GO:0002164 104 0.150
Worm Fly
cell cycle dna replication GO:0044786 23 0.149
cellular protein modification process GO:0006464 438 0.147
anterior posterior axis specification embryo GO:0008595 103 0.145
tube formation GO:0035148 21 0.144
multicellular organism growth GO:0035264 46 0.142
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.140
Human Mouse Rat
fibroblast growth factor receptor signaling pathway GO:0008543 10 0.140
Human Zebrafish Mouse Rat Worm
wing disc morphogenesis GO:0007472 344 0.138
signal transduction by phosphorylation GO:0023014 107 0.137
positive regulation of protein metabolic process GO:0051247 128 0.136
regulation of cellular component biogenesis GO:0044087 201 0.135
positive regulation of developmental process GO:0051094 143 0.131
Human Mouse Rat
nephron tubule morphogenesis GO:0072078 3 0.130
organ induction GO:0001759 3 0.128
Mouse
positive regulation of growth GO:0045927 75 0.128
Mouse
cell growth GO:0016049 108 0.127
intracellular transport GO:0046907 228 0.127
actin filament bundle organization GO:0061572 28 0.127
regionalization GO:0003002 416 0.127
Zebrafish Mouse
mapk cascade GO:0000165 107 0.127
regulation of protein phosphorylation GO:0001932 64 0.126
developmental programmed cell death GO:0010623 138 0.126
regulation of phosphorylation GO:0042325 147 0.126
intracellular protein transport GO:0006886 104 0.124
organic substance transport GO:0071702 257 0.124
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.124
negative regulation of programmed cell death GO:0043069 72 0.122
Mouse
protein complex biogenesis GO:0070271 201 0.120
organelle assembly GO:0070925 198 0.118
Zebrafish
exocrine system development GO:0035272 162 0.117
Mouse
tripartite regional subdivision GO:0007351 103 0.117
regulation of hemocyte differentiation GO:0045610 22 0.116
actin filament based process GO:0030029 220 0.116
chitin based cuticle development GO:0040003 49 0.115
positive regulation of cellular protein metabolic process GO:0032270 118 0.115
organonitrogen compound biosynthetic process GO:1901566 117 0.115
filtration diaphragm assembly GO:0036058 4 0.114
nucleocytoplasmic transport GO:0006913 72 0.114
adherens junction organization GO:0034332 27 0.112
neural precursor cell proliferation GO:0061351 75 0.112
Zebrafish Mouse
death GO:0016265 284 0.111
Human Mouse
regulation of protein transport GO:0051223 57 0.108
regulation of map kinase activity GO:0043405 17 0.106
developmental cell growth GO:0048588 52 0.106
r7 cell differentiation GO:0045466 43 0.106
organonitrogen compound metabolic process GO:1901564 318 0.105
neuron fate commitment GO:0048663 50 0.105
actin cytoskeleton organization GO:0030036 206 0.104
dna endoreduplication GO:0042023 22 0.104
cellular ketone metabolic process GO:0042180 24 0.104
Human Mouse
camera type eye morphogenesis GO:0048593 2 0.102
Mouse
hemocyte differentiation GO:0042386 38 0.101
regulation of cysteine type endopeptidase activity GO:2000116 27 0.101
compound eye photoreceptor fate commitment GO:0001752 36 0.101
response to fibroblast growth factor GO:0071774 10 0.100
Human Zebrafish Mouse Rat Worm
positive regulation of mapk cascade GO:0043410 63 0.100
negative regulation of cell fate specification GO:0009996 15 0.100
Zebrafish
organelle localization GO:0051640 148 0.099
Mouse
positive regulation of proteolysis GO:0045862 52 0.098
Human
chemosensory behavior GO:0007635 106 0.098
genital disc development GO:0035215 44 0.097
programmed cell death GO:0012501 257 0.096
Human Mouse
catabolic process GO:0009056 409 0.096
Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.096
proteolysis GO:0006508 192 0.096
Human
post embryonic appendage morphogenesis GO:0035120 385 0.095
striated muscle cell differentiation GO:0051146 90 0.094
Fly
cytoplasmic transport GO:0016482 130 0.094
establishment of blood brain barrier GO:0060856 16 0.094
neuron recognition GO:0008038 101 0.092
imaginal disc derived wing morphogenesis GO:0007476 337 0.091
phosphorylation GO:0016310 294 0.090
developmental growth involved in morphogenesis GO:0060560 65 0.090
ovarian follicle cell migration GO:0007297 121 0.090
glial cell migration GO:0008347 31 0.090
protein import GO:0017038 55 0.089
eye photoreceptor cell development GO:0042462 81 0.088
positive regulation of cellular component biogenesis GO:0044089 80 0.087
gonad development GO:0008406 50 0.087
Worm Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.086
homeostatic process GO:0042592 199 0.086
Zebrafish Mouse
chorion containing eggshell formation GO:0007304 105 0.086
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.084
Mouse
positive regulation of gene expression GO:0010628 290 0.084
Mouse Rat
negative regulation of multicellular organismal process GO:0051241 142 0.084
dorsal closure GO:0007391 79 0.084
embryonic epithelial tube formation GO:0001838 6 0.082
photoreceptor cell fate commitment GO:0046552 41 0.081
nephron tubule development GO:0072080 3 0.081
single organism cell adhesion GO:0098602 47 0.081
protein targeting to nucleus GO:0044744 51 0.080
cellular response to fibroblast growth factor stimulus GO:0044344 10 0.080
Human Zebrafish Mouse Rat Worm
embryonic organ development GO:0048568 50 0.080
Human Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.080
spindle organization GO:0007051 253 0.079
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.078
vesicle mediated transport GO:0016192 381 0.078
Mouse Worm
salivary gland development GO:0007431 162 0.078
Mouse
neuromuscular junction development GO:0007528 149 0.078
Mouse
synaptic transmission GO:0007268 288 0.078
Mouse
response to growth factor GO:0070848 31 0.078
Human Zebrafish Mouse Rat Worm
cell recognition GO:0008037 102 0.078
development of primary sexual characteristics GO:0045137 50 0.077
Worm Fly
gland development GO:0048732 191 0.077
Zebrafish Mouse Fly
nuclear division GO:0000280 332 0.077
Mouse
glial cell development GO:0021782 27 0.077
Mouse
regulation of axon guidance GO:1902667 10 0.077
response to organic cyclic compound GO:0014070 89 0.076
positive regulation of developmental growth GO:0048639 62 0.076
Mouse
establishment of protein localization GO:0045184 163 0.076
stem cell proliferation GO:0072089 88 0.076
Mouse Rat
body morphogenesis GO:0010171 2 0.075
regulation of cellular localization GO:0060341 136 0.075
kidney epithelium development GO:0072073 3 0.075
Mouse
retina development in camera type eye GO:0060041 4 0.075
organelle fission GO:0048285 340 0.075
Mouse
cellular protein localization GO:0034613 160 0.074
axon choice point recognition GO:0016198 26 0.074
positive regulation of catalytic activity GO:0043085 118 0.073
inter male aggressive behavior GO:0002121 60 0.073
small molecule metabolic process GO:0044281 305 0.073
Human Mouse
protein phosphorylation GO:0006468 169 0.072
renal filtration cell differentiation GO:0061318 12 0.071
Fly
nuclear transport GO:0051169 72 0.071
cell death GO:0008219 279 0.071
Human Mouse
sensory perception of mechanical stimulus GO:0050954 72 0.070
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 210 0.070
Mouse
positive regulation of secretion GO:0051047 22 0.070
oocyte development GO:0048599 124 0.069
dendrite development GO:0016358 204 0.069
anterior posterior axis specification GO:0009948 109 0.069
cardioblast cell fate specification GO:0042685 9 0.068
cellular catabolic process GO:0044248 372 0.068
limb morphogenesis GO:0035108 1 0.067
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 13 0.067
Mouse
aggressive behavior GO:0002118 63 0.066
regulation of cell motility GO:2000145 23 0.066
terminal region determination GO:0007362 25 0.066
regulation of cell death GO:0010941 173 0.065
Mouse
nephron development GO:0072006 3 0.065
regulation of locomotion GO:0040012 42 0.064
axon extension involved in axon guidance GO:0048846 10 0.064
regulation of cell migration GO:0030334 22 0.064
regulation of cell size GO:0008361 63 0.064
establishment of localization in cell GO:0051649 402 0.063
Mouse Worm
activation of protein kinase activity GO:0032147 12 0.063
regulation of establishment of protein localization GO:0070201 61 0.063
regulation of cell cycle GO:0051726 291 0.063
Mouse
fusion cell fate specification GO:0035156 4 0.063
r3 r4 cell differentiation GO:0048056 12 0.063
regulation of organ morphogenesis GO:2000027 78 0.062
Mouse
regulation of transport GO:0051049 181 0.062
regulation of anatomical structure size GO:0090066 163 0.062
response to sterol GO:0036314 34 0.062
determination of genital disc primordium GO:0035225 10 0.061
anatomical structure homeostasis GO:0060249 97 0.061
Zebrafish
cation transport GO:0006812 110 0.061
regulation of apoptotic process GO:0042981 130 0.061
Mouse
negative regulation of phosphorylation GO:0042326 35 0.060
regulation of protein kinase activity GO:0045859 51 0.060
regulation of cellular response to stress GO:0080135 89 0.059
regulation of developmental pigmentation GO:0048070 24 0.059
hindbrain development GO:0030902 2 0.059
regulation of response to stress GO:0080134 200 0.059
Fly
single organism biosynthetic process GO:0044711 206 0.058
Human Mouse
regulation of secretion GO:0051046 44 0.058
mitotic spindle organization GO:0007052 220 0.058
ribonucleotide catabolic process GO:0009261 109 0.058
digestive tract morphogenesis GO:0048546 127 0.058
Zebrafish Mouse Rat Worm Fly
macromolecular complex assembly GO:0065003 256 0.058
negative regulation of organelle organization GO:0010639 56 0.057
Mouse
limb development GO:0060173 1 0.057
Mouse
regulation of molecular function GO:0065009 217 0.057
regulation of embryonic development GO:0045995 68 0.056
Zebrafish Mouse
cellular response to hormone stimulus GO:0032870 44 0.056
regulation of epithelial cell migration GO:0010632 12 0.056
regulation of cellular ketone metabolic process GO:0010565 3 0.056
Human Mouse
establishment of tissue polarity GO:0007164 87 0.056
secretion GO:0046903 109 0.056
Worm
cuticle pattern formation GO:0035017 27 0.055
oxoacid metabolic process GO:0043436 103 0.055
Human Mouse
positive regulation of cell proliferation GO:0008284 47 0.055
Human Mouse Rat
positive regulation of phosphorus metabolic process GO:0010562 139 0.054
nephron morphogenesis GO:0072028 3 0.054
negative regulation of cell proliferation GO:0008285 69 0.054
Mouse Rat
negative regulation of response to stimulus GO:0048585 258 0.054
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.054
positive regulation of protein modification process GO:0031401 58 0.053
regulation of dna metabolic process GO:0051052 34 0.053
Human
positive regulation of transport GO:0051050 92 0.053
positive regulation of multicellular organism growth GO:0040018 21 0.053
cytokinesis GO:0000910 90 0.052
regulation of synapse structure and activity GO:0050803 128 0.052
positive regulation of protein transport GO:0051222 37 0.052
motor neuron axon guidance GO:0008045 58 0.052
epithelial tube formation GO:0072175 7 0.051
regulation of epithelial cell proliferation GO:0050678 4 0.051
Mouse Rat
single organism nuclear import GO:1902593 51 0.051
regulation of chromosome organization GO:0033044 64 0.051
response to oxygen containing compound GO:1901700 200 0.051
activation of mapk activity GO:0000187 9 0.050
embryonic development via the syncytial blastoderm GO:0001700 148 0.050
regulation of mapk cascade GO:0043408 92 0.050
cellular macromolecule localization GO:0070727 220 0.049
muscle organ development GO:0007517 127 0.049
Mouse Worm Fly
reproductive system development GO:0061458 74 0.049
Mouse Worm Fly
regulation of cell fate specification GO:0042659 27 0.048
Zebrafish Mouse
axon midline choice point recognition GO:0016199 26 0.048
oocyte differentiation GO:0009994 145 0.048
nephron epithelium morphogenesis GO:0072088 3 0.048
regulation of proteolysis GO:0030162 87 0.047
Human
single organism catabolic process GO:0044712 228 0.047
regulation of endopeptidase activity GO:0052548 36 0.046
positive regulation of peptidase activity GO:0010952 29 0.046
regulation of protein localization GO:0032880 76 0.046
morphogenesis of a polarized epithelium GO:0001738 93 0.046
tube fusion GO:0035146 17 0.046
positive regulation of molecular function GO:0044093 136 0.046
regulation of intracellular signal transduction GO:1902531 236 0.046
compound eye photoreceptor development GO:0042051 78 0.045
negative regulation of protein metabolic process GO:0051248 85 0.045
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.045
regulation of kinase activity GO:0043549 53 0.045
protein complex assembly GO:0006461 200 0.045
chromosome organization GO:0051276 360 0.045
regulation of catalytic activity GO:0050790 185 0.045
multi multicellular organism process GO:0044706 123 0.045
Worm
positive regulation of secretion by cell GO:1903532 20 0.045
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.044
positive regulation of protein kinase activity GO:0045860 25 0.044
negative regulation of intracellular signal transduction GO:1902532 57 0.044
regulation of cell shape GO:0008360 113 0.043
Fly
regulation of transferase activity GO:0051338 58 0.043
regulation of response to external stimulus GO:0032101 115 0.043
cellular response to extracellular stimulus GO:0031668 64 0.043
regulation of axon extension GO:0030516 8 0.042
synapse assembly GO:0007416 143 0.042
peptidyl amino acid modification GO:0018193 105 0.042
Human Zebrafish Mouse Rat Fly
pigmentation GO:0043473 75 0.042
determination of imaginal disc primordium GO:0007445 11 0.042
kidney morphogenesis GO:0060993 3 0.042
cellular protein complex assembly GO:0043623 71 0.042
cell type specific apoptotic process GO:0097285 38 0.041
Mouse
cellular macromolecular complex assembly GO:0034622 153 0.041
dendrite morphogenesis GO:0048813 199 0.041
biological adhesion GO:0022610 138 0.041
regulation of protein modification process GO:0031399 112 0.041
positive regulation of cell communication GO:0010647 250 0.041
negative regulation of cardiac cell fate specification GO:2000044 7 0.041
heterocycle catabolic process GO:0046700 166 0.041
sensory perception of sound GO:0007605 56 0.041
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 119 0.040
regulation of multi organism process GO:0043900 131 0.040
hematopoietic or lymphoid organ development GO:0048534 57 0.040
Mouse Fly
regulation of protein polymerization GO:0032271 28 0.040
autophagy GO:0006914 108 0.040
cellular amino acid metabolic process GO:0006520 61 0.040
regulation of protein complex assembly GO:0043254 42 0.040
response to extracellular stimulus GO:0009991 116 0.040
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.039
positive regulation of endopeptidase activity GO:0010950 26 0.039
developmental induction GO:0031128 3 0.039
Mouse
regulation of cell fate commitment GO:0010453 29 0.039
Zebrafish Mouse
smoothened signaling pathway GO:0007224 49 0.039
Mouse
single organism behavior GO:0044708 391 0.039
protein polymerization GO:0051258 42 0.039
memory GO:0007613 94 0.038
protein localization to organelle GO:0033365 82 0.038
protein maturation GO:0051604 71 0.038
carbohydrate derivative biosynthetic process GO:1901137 85 0.038
pole plasm assembly GO:0007315 61 0.038
regulation of cellular component movement GO:0051270 42 0.038
pericardial nephrocyte differentiation GO:0061320 9 0.037
Fly
positive regulation of nervous system development GO:0051962 69 0.037
Human Mouse Rat
striated muscle tissue development GO:0014706 27 0.037
Zebrafish Mouse
dna conformation change GO:0071103 105 0.037
positive regulation of programmed cell death GO:0043068 62 0.037
Mouse
eggshell chorion assembly GO:0007306 66 0.036
negative regulation of cell cycle process GO:0010948 109 0.036
Mouse
amine metabolic process GO:0009308 12 0.036
response to wounding GO:0009611 94 0.036
Zebrafish Mouse Fly
regulation of cytoskeleton organization GO:0051493 89 0.036
regulation of defense response GO:0031347 102 0.036
Fly
chromatin organization GO:0006325 207 0.036
negative regulation of smoothened signaling pathway GO:0045879 16 0.035
Mouse
protein modification by small protein conjugation GO:0032446 79 0.035
Mouse
regulation of synapse organization GO:0050807 110 0.035
circulatory system development GO:0072359 82 0.035
Zebrafish Mouse Fly
cellular response to decreased oxygen levels GO:0036294 30 0.035
regulation of cell division GO:0051302 72 0.035
Mouse
nucleotide metabolic process GO:0009117 161 0.035
carbohydrate derivative metabolic process GO:1901135 217 0.034
photoreceptor cell development GO:0042461 96 0.034
positive regulation of signal transduction GO:0009967 223 0.034
synaptic growth at neuromuscular junction GO:0051124 119 0.034
muscle fiber development GO:0048747 12 0.034
Fly
nucleoside triphosphate catabolic process GO:0009143 108 0.033
ribonucleoside triphosphate catabolic process GO:0009203 108 0.033
neuromuscular synaptic transmission GO:0007274 67 0.033
nephron epithelium development GO:0072009 3 0.033
negative regulation of cell cycle GO:0045786 116 0.033
Mouse
long term memory GO:0007616 62 0.033
pole plasm rna localization GO:0007316 52 0.033
response to ecdysone GO:0035075 34 0.033
organic acid metabolic process GO:0006082 103 0.033
Human Mouse
heart development GO:0007507 82 0.033
Zebrafish Mouse Fly
small gtpase mediated signal transduction GO:0007264 88 0.032
hemopoiesis GO:0030097 46 0.032
Mouse
regulation of nucleocytoplasmic transport GO:0046822 35 0.032
sensory perception GO:0007600 196 0.032
Mouse Rat
glial cell differentiation GO:0010001 35 0.032
Mouse Fly
ion transport GO:0006811 145 0.032
response to nutrient levels GO:0031667 114 0.032
neurological system process GO:0050877 358 0.032
Mouse Rat
positive regulation of response to wounding GO:1903036 15 0.032
Fly
establishment of protein localization to organelle GO:0072594 62 0.032

btl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
Human
nervous system disease DOID:863 0 0.052