Drosophila melanogaster

9 known processes

ClC-b (Dmel_CG8594)

Chloride channel-b

(Aliases: DmClCb,CG8594,DmClC-b,Dmel\CG8594)

ClC-b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of touch GO:0050975 11 0.853
single organism behavior GO:0044708 391 0.627
ion transmembrane transport GO:0034220 122 0.272
regulation of ion transport GO:0043269 39 0.267
sensory perception of mechanical stimulus GO:0050954 72 0.210
sensory perception GO:0007600 196 0.196
growth GO:0040007 359 0.140
learning or memory GO:0007611 141 0.125
endocytosis GO:0006897 310 0.118
organic substance transport GO:0071702 257 0.113
regulation of growth GO:0040008 233 0.092
cognition GO:0050890 141 0.088
response to other organism GO:0051707 293 0.088
locomotory behavior GO:0007626 176 0.076
intracellular signal transduction GO:0035556 300 0.075
phagocytosis GO:0006909 215 0.071
vesicle mediated transport GO:0016192 381 0.071
single organism membrane fusion GO:0044801 42 0.070
positive regulation of signal transduction GO:0009967 223 0.066
response to bacterium GO:0009617 198 0.065
death GO:0016265 284 0.065
positive regulation of response to stimulus GO:0048584 323 0.064
neurological system process GO:0050877 358 0.064
regulation of transport GO:0051049 181 0.063
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.060
response to biotic stimulus GO:0009607 294 0.060
cation transmembrane transport GO:0098655 88 0.060
response to monosaccharide GO:0034284 4 0.060
synaptic transmission GO:0007268 288 0.059
metal ion homeostasis GO:0055065 44 0.058
transmembrane transport GO:0055085 139 0.055
ras protein signal transduction GO:0007265 88 0.052
chemical homeostasis GO:0048878 92 0.050
glycosyl compound metabolic process GO:1901657 127 0.049
response to external biotic stimulus GO:0043207 293 0.048
organic substance catabolic process GO:1901575 308 0.047
response to pheromone GO:0019236 19 0.047
regionalization GO:0003002 416 0.044
regulation of localization GO:0032879 275 0.043
programmed cell death GO:0012501 257 0.043
digestive tract morphogenesis GO:0048546 127 0.043
cation transport GO:0006812 110 0.042
nucleoside phosphate metabolic process GO:0006753 162 0.040
nitrogen compound transport GO:0071705 85 0.040
apoptotic process GO:0006915 159 0.039
organophosphate metabolic process GO:0019637 195 0.039
purine ribonucleoside metabolic process GO:0046128 127 0.039
cell death GO:0008219 279 0.039
male courtship behavior GO:0008049 63 0.038
regulation of anatomical structure size GO:0090066 163 0.038
regulation of metal ion transport GO:0010959 15 0.036
heterocycle catabolic process GO:0046700 166 0.036
embryonic morphogenesis GO:0048598 206 0.036
neuromuscular synaptic transmission GO:0007274 67 0.035
regulation of synapse structure and activity GO:0050803 128 0.034
determination of adult lifespan GO:0008340 137 0.034
nucleotide metabolic process GO:0009117 161 0.034
multi multicellular organism process GO:0044706 123 0.034
regulation of nervous system development GO:0051960 248 0.033
positive regulation of signaling GO:0023056 243 0.033
small molecule metabolic process GO:0044281 305 0.033
cation homeostasis GO:0055080 51 0.033
cell migration GO:0016477 238 0.033
regulation of anatomical structure morphogenesis GO:0022603 242 0.033
defense response to other organism GO:0098542 225 0.033
nucleoside metabolic process GO:0009116 127 0.031
cellular response to chemical stimulus GO:0070887 199 0.031
multicellular organismal reproductive behavior GO:0033057 110 0.031
negative regulation of cellular metabolic process GO:0031324 382 0.031
multi organism behavior GO:0051705 175 0.029
gastrulation GO:0007369 70 0.029
ion transport GO:0006811 145 0.029
regulation of protein localization GO:0032880 76 0.029
response to wounding GO:0009611 94 0.028
regulation of cell death GO:0010941 173 0.027
mechanosensory behavior GO:0007638 12 0.027
defense response to bacterium GO:0042742 178 0.027
enzyme linked receptor protein signaling pathway GO:0007167 179 0.027
defense response GO:0006952 300 0.027
single organism carbohydrate metabolic process GO:0044723 72 0.027
response to glucose GO:0009749 2 0.027
anion transport GO:0006820 41 0.026
detection of stimulus GO:0051606 156 0.026
macromolecular complex assembly GO:0065003 256 0.026
protein localization GO:0008104 284 0.026
nucleobase containing small molecule metabolic process GO:0055086 174 0.025
developmental growth GO:0048589 280 0.025
negative regulation of cellular component organization GO:0051129 108 0.025
organic acid metabolic process GO:0006082 103 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
regulation of developmental growth GO:0048638 174 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
body morphogenesis GO:0010171 2 0.023
g2 dna damage checkpoint GO:0031572 69 0.022
regulation of behavior GO:0050795 75 0.022
tube morphogenesis GO:0035239 191 0.022
purine nucleoside metabolic process GO:0042278 127 0.022
cellular protein complex assembly GO:0043623 71 0.022
vacuole organization GO:0007033 8 0.022
response to hexose GO:0009746 3 0.022
small gtpase mediated signal transduction GO:0007264 88 0.021
metal ion transport GO:0030001 74 0.021
ribonucleoside catabolic process GO:0042454 112 0.021
positive regulation of transport GO:0051050 92 0.021
actin filament based movement GO:0030048 26 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
calcium ion transport GO:0006816 24 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.021
multicellular organismal aging GO:0010259 140 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.020
single organism catabolic process GO:0044712 228 0.020
negative regulation of cell death GO:0060548 81 0.020
regulation of apoptotic process GO:0042981 130 0.020
learning GO:0007612 75 0.019
aging GO:0007568 143 0.019
protein transport GO:0015031 155 0.019
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
positive regulation of cell communication GO:0010647 250 0.019
regulation of hemocyte proliferation GO:0035206 37 0.019
sensory perception of pain GO:0019233 4 0.019
carboxylic acid transport GO:0046942 18 0.019
amino acid transport GO:0006865 12 0.019
divalent inorganic cation transport GO:0072511 30 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.019
ion homeostasis GO:0050801 55 0.019
nucleoside catabolic process GO:0009164 112 0.018
response to osmotic stress GO:0006970 14 0.018
wound healing GO:0042060 75 0.018
cell type specific apoptotic process GO:0097285 38 0.018
organonitrogen compound metabolic process GO:1901564 318 0.017
forebrain development GO:0030900 2 0.017
monovalent inorganic cation transport GO:0015672 40 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
meiotic nuclear division GO:0007126 151 0.017
neuron recognition GO:0008038 101 0.017
sensory perception of chemical stimulus GO:0007606 116 0.017
larval locomotory behavior GO:0008345 27 0.017
response to organic substance GO:0010033 284 0.017
regulation of cell differentiation GO:0045595 302 0.017
ovarian follicle cell development GO:0030707 248 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
aggressive behavior GO:0002118 63 0.016
secretion GO:0046903 109 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
purine containing compound catabolic process GO:0072523 112 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
regulation of ras protein signal transduction GO:0046578 93 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
cellular catabolic process GO:0044248 372 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.015
translation GO:0006412 69 0.015
response to acid chemical GO:0001101 25 0.015
phosphorylation GO:0016310 294 0.015
regulation of neuron death GO:1901214 26 0.015
protein complex biogenesis GO:0070271 201 0.015
membrane organization GO:0061024 112 0.015
rna transport GO:0050658 46 0.015
epiboly GO:0090504 2 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
homeostatic process GO:0042592 199 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
central nervous system development GO:0007417 201 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
monocarboxylic acid transport GO:0015718 3 0.015
behavioral response to pain GO:0048266 3 0.014
nucleotide catabolic process GO:0009166 109 0.014
purine nucleoside monophosphate catabolic process GO:0009128 38 0.014
epiboly involved in wound healing GO:0090505 2 0.014
localization of cell GO:0051674 257 0.014
establishment of localization in cell GO:0051649 402 0.014
organelle fission GO:0048285 340 0.014
divalent metal ion transport GO:0070838 26 0.014
regulation of organelle organization GO:0033043 196 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
organelle fusion GO:0048284 46 0.014
associative learning GO:0008306 65 0.014
catabolic process GO:0009056 409 0.014
mapk cascade GO:0000165 107 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
purine containing compound metabolic process GO:0072521 155 0.013
organic acid transport GO:0015849 18 0.013
organic anion transport GO:0015711 28 0.013
gtp catabolic process GO:0006184 72 0.013
protein polymerization GO:0051258 42 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
connective tissue development GO:0061448 3 0.013
regulation of vesicle mediated transport GO:0060627 59 0.013
pharynx development GO:0060465 1 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
regulation of cell morphogenesis GO:0022604 163 0.013
negative regulation of cell communication GO:0010648 223 0.013
drinking behavior GO:0042756 2 0.013
chemotaxis GO:0006935 249 0.013
immune system process GO:0002376 347 0.012
biological adhesion GO:0022610 138 0.012
response to oxygen containing compound GO:1901700 200 0.012
camera type eye morphogenesis GO:0048593 2 0.012
protein modification process GO:0036211 438 0.012
limb development GO:0060173 1 0.012
organophosphate catabolic process GO:0046434 112 0.012
larval development GO:0002164 104 0.012
hindbrain development GO:0030902 2 0.012
anion transmembrane transport GO:0098656 26 0.012
regulation of programmed cell death GO:0043067 152 0.012
establishment of protein localization GO:0045184 163 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
membrane fusion GO:0061025 42 0.012
lipid modification GO:0030258 24 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
response to decreased oxygen levels GO:0036293 58 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
digestive system development GO:0055123 149 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
retina development in camera type eye GO:0060041 4 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
regulation of mapk cascade GO:0043408 92 0.011
rrna processing GO:0006364 3 0.011
regulation of endocytosis GO:0030100 37 0.011
actin filament organization GO:0007015 126 0.011
regulation of system process GO:0044057 36 0.011
epithelial cell differentiation GO:0030855 322 0.011
actin cytoskeleton organization GO:0030036 206 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
neuron death GO:0070997 27 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
protein complex assembly GO:0006461 200 0.011
mating GO:0007618 120 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
response to salt stress GO:0009651 11 0.010
adult locomotory behavior GO:0008344 76 0.010
organelle assembly GO:0070925 198 0.010
cell motility GO:0048870 251 0.010
positive regulation of biosynthetic process GO:0009891 316 0.010
negative regulation of nervous system development GO:0051961 92 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
cellular response to dna damage stimulus GO:0006974 223 0.010
negative regulation of signaling GO:0023057 219 0.010

ClC-b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.145
Human
respiratory system disease DOID:1579 0 0.033
lower respiratory tract disease DOID:0050161 0 0.033
bronchial disease DOID:1176 0 0.033
nervous system disease DOID:863 0 0.025
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.011