Drosophila melanogaster

29 known processes

Hsc70-5 (Dmel_CG8542)

Heat shock protein cognate 5

(Aliases: CG8542,Dmel\CG8542,Hsc70,HSC70,dhsc70,Hsc5,Hsc-5,HSC-70,hsc70,HSC5,l(2)k04907,hsc70-5)

Hsc70-5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion morphogenesis GO:0070584 8 0.901
mitochondrion organization GO:0007005 65 0.887
trna aminoacylation for protein translation GO:0006418 2 0.666
cation transport GO:0006812 110 0.499
regulation of anatomical structure morphogenesis GO:0022603 242 0.268
trna aminoacylation GO:0043039 2 0.259
transmembrane transport GO:0055085 139 0.255
Yeast
small molecule metabolic process GO:0044281 305 0.247
Yeast
catabolic process GO:0009056 409 0.247
intracellular protein transmembrane transport GO:0065002 4 0.238
Yeast
response to abiotic stimulus GO:0009628 341 0.223
intracellular signal transduction GO:0035556 300 0.206
ion transmembrane transport GO:0034220 122 0.181
organonitrogen compound metabolic process GO:1901564 318 0.180
Yeast
ion transport GO:0006811 145 0.163
endocytosis GO:0006897 310 0.157
response to bacterium GO:0009617 198 0.141
sperm mitochondrion organization GO:0030382 7 0.125
cellular component disassembly GO:0022411 46 0.122
growth GO:0040007 359 0.113
developmental growth GO:0048589 280 0.112
multicellular organismal homeostasis GO:0048871 41 0.107
blastoderm segmentation GO:0007350 159 0.105
cellular catabolic process GO:0044248 372 0.105
dorsal ventral pattern formation GO:0009953 133 0.103
cellular response to chemical stimulus GO:0070887 199 0.103
Rat
positive regulation of response to stimulus GO:0048584 323 0.097
single organism membrane organization GO:0044802 93 0.096
purine nucleoside monophosphate metabolic process GO:0009126 50 0.095
Yeast
organelle fusion GO:0048284 46 0.094
response to wounding GO:0009611 94 0.091
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.087
Yeast
metal ion transport GO:0030001 74 0.086
positive regulation of mitochondrion organization GO:0010822 8 0.085
vesicle mediated transport GO:0016192 381 0.084
atp metabolic process GO:0046034 49 0.084
Yeast
regulation of mitochondrial fusion GO:0010635 5 0.083
organic acid metabolic process GO:0006082 103 0.077
positive regulation of cellular biosynthetic process GO:0031328 316 0.077
positive regulation of macromolecule metabolic process GO:0010604 405 0.076
Yeast
homeostatic process GO:0042592 199 0.074
positive regulation of transcription dna templated GO:0045893 266 0.072
carboxylic acid metabolic process GO:0019752 92 0.071
divalent inorganic cation homeostasis GO:0072507 29 0.069
positive regulation of developmental growth GO:0048639 62 0.068
amino acid activation GO:0043038 3 0.068
aromatic compound catabolic process GO:0019439 166 0.067
Yeast
oxoacid metabolic process GO:0043436 103 0.067
ribonucleoside monophosphate metabolic process GO:0009161 51 0.065
Yeast
regulation of mitochondrial fission GO:0090140 7 0.065
regulation of intracellular signal transduction GO:1902531 236 0.063
response to temperature stimulus GO:0009266 106 0.061
inorganic cation transmembrane transport GO:0098662 61 0.060
wound healing GO:0042060 75 0.059
protein transmembrane transport GO:0071806 4 0.058
Yeast
positive regulation of protein metabolic process GO:0051247 128 0.058
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.057
ribonucleoside metabolic process GO:0009119 127 0.055
Yeast
response to biotic stimulus GO:0009607 294 0.055
regulation of multicellular organismal development GO:2000026 414 0.051
regulation of mitochondrion organization GO:0010821 12 0.051
cellular lipid metabolic process GO:0044255 83 0.050
cellular amino acid metabolic process GO:0006520 61 0.050
proteolysis GO:0006508 192 0.050
single organism biosynthetic process GO:0044711 206 0.049
anatomical structure homeostasis GO:0060249 97 0.049
nucleoside monophosphate metabolic process GO:0009123 52 0.047
Yeast
cellular response to organic substance GO:0071310 132 0.046
Rat
positive regulation of developmental process GO:0051094 143 0.046
positive regulation of cellular component organization GO:0051130 156 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.045
inositol lipid mediated signaling GO:0048017 4 0.044
inorganic ion transmembrane transport GO:0098660 73 0.044
response to organic substance GO:0010033 284 0.044
Rat
response to other organism GO:0051707 293 0.043
cellular macromolecule catabolic process GO:0044265 136 0.041
Yeast
positive regulation of rna metabolic process GO:0051254 271 0.040
regulation of protein metabolic process GO:0051246 256 0.040
mitochondrial fusion GO:0008053 7 0.040
organophosphate metabolic process GO:0019637 195 0.040
Yeast
phagocytosis GO:0006909 215 0.039
organic substance catabolic process GO:1901575 308 0.039
Yeast
regulation of cell morphogenesis GO:0022604 163 0.039
negative regulation of gene expression GO:0010629 387 0.038
mitochondrial transport GO:0006839 8 0.037
Yeast
positive regulation of gene expression GO:0010628 290 0.037
positive regulation of biosynthetic process GO:0009891 316 0.037
lipid metabolic process GO:0006629 121 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.036
Yeast
protein maturation GO:0051604 71 0.035
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.035
Yeast
purine nucleoside metabolic process GO:0042278 127 0.034
Yeast
protein catabolic process GO:0030163 101 0.034
establishment of localization in cell GO:0051649 402 0.032
Yeast Mouse
regulation of cell shape GO:0008360 113 0.032
positive regulation of nucleic acid templated transcription GO:1903508 266 0.031
anterior posterior axis specification GO:0009948 109 0.030
response to unfolded protein GO:0006986 9 0.030
single organism cellular localization GO:1902580 180 0.030
Yeast
negative regulation of signal transduction GO:0009968 206 0.029
localization of cell GO:0051674 257 0.029
cellular response to hormone stimulus GO:0032870 44 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.029
connective tissue development GO:0061448 3 0.029
membrane fusion GO:0061025 42 0.029
regulation of tor signaling GO:0032006 21 0.028
macromolecule catabolic process GO:0009057 161 0.028
Yeast
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.028
positive regulation of signal transduction GO:0009967 223 0.028
regulation of developmental growth GO:0048638 174 0.028
membrane organization GO:0061024 112 0.027
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
regulation of cellular catabolic process GO:0031329 157 0.026
Yeast
cell migration GO:0016477 238 0.026
ribonucleoprotein complex subunit organization GO:0071826 28 0.026
nucleobase containing small molecule metabolic process GO:0055086 174 0.026
Yeast
transcription from rna polymerase ii promoter GO:0006366 368 0.025
positive regulation of cell communication GO:0010647 250 0.025
regulation of response to stress GO:0080134 200 0.025
regulation of cell proliferation GO:0042127 163 0.025
cellular amine metabolic process GO:0044106 12 0.025
cellular protein modification process GO:0006464 438 0.025
jak stat cascade GO:0007259 49 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.025
cellular protein catabolic process GO:0044257 83 0.025
regulation of organelle organization GO:0033043 196 0.025
purine nucleotide catabolic process GO:0006195 109 0.025
Yeast
ribose phosphate metabolic process GO:0019693 145 0.024
Yeast
positive regulation of multicellular organismal process GO:0051240 143 0.024
organophosphate biosynthetic process GO:0090407 46 0.024
regulation of growth GO:0040008 233 0.024
protein processing GO:0016485 68 0.024
organelle fission GO:0048285 340 0.024
response to external biotic stimulus GO:0043207 293 0.024
lipid biosynthetic process GO:0008610 46 0.024
negative regulation of cell death GO:0060548 81 0.024
reactive oxygen species metabolic process GO:0072593 22 0.024
embryonic pattern specification GO:0009880 174 0.024
axis specification GO:0009798 167 0.023
positive regulation of intracellular signal transduction GO:1902533 116 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
regulation of catabolic process GO:0009894 170 0.023
Yeast
metal ion homeostasis GO:0055065 44 0.023
regionalization GO:0003002 416 0.023
cell motility GO:0048870 251 0.023
oxidation reduction process GO:0055114 123 0.023
single organism catabolic process GO:0044712 228 0.022
Yeast
purine ribonucleoside metabolic process GO:0046128 127 0.022
Yeast
organophosphate catabolic process GO:0046434 112 0.022
Yeast
programmed cell death GO:0012501 257 0.022
negative regulation of growth GO:0045926 84 0.022
defense response to other organism GO:0098542 225 0.022
cellular macromolecule localization GO:0070727 220 0.022
Yeast Mouse
regulation of endopeptidase activity GO:0052548 36 0.021
negative regulation of apoptotic process GO:0043066 63 0.021
positive regulation of signaling GO:0023056 243 0.021
nucleotide metabolic process GO:0009117 161 0.021
Yeast
mitochondrial atp synthesis coupled electron transport GO:0042775 8 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
Yeast
learning GO:0007612 75 0.021
regulation of molecular function GO:0065009 217 0.020
Yeast
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.020
positive regulation of catalytic activity GO:0043085 118 0.019
Yeast
anterior posterior axis specification embryo GO:0008595 103 0.019
cardiolipin metabolic process GO:0032048 1 0.019
translation GO:0006412 69 0.019
phosphorylation GO:0016310 294 0.019
kidney development GO:0001822 3 0.019
response to lipopolysaccharide GO:0032496 4 0.019
purine nucleoside triphosphate metabolic process GO:0009144 119 0.019
Yeast
anion transport GO:0006820 41 0.018
xenobiotic transport GO:0042908 1 0.018
amine metabolic process GO:0009308 12 0.018
translational elongation GO:0006414 4 0.018
cell proliferation GO:0008283 299 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.017
Yeast
glial cell differentiation GO:0010001 35 0.017
mitotic sister chromatid segregation GO:0000070 87 0.017
rac protein signal transduction GO:0016601 3 0.017
entry into cell of other organism involved in symbiotic interaction GO:0051806 3 0.017
transition metal ion transport GO:0000041 16 0.017
positive regulation of multicellular organism growth GO:0040018 21 0.017
phosphatidylinositol mediated signaling GO:0048015 4 0.017
macromolecular complex disassembly GO:0032984 37 0.017
regulation of phosphate metabolic process GO:0019220 210 0.017
cellular respiration GO:0045333 26 0.017
segmentation GO:0035282 207 0.017
positive regulation of molecular function GO:0044093 136 0.017
Yeast
regulation of phosphorylation GO:0042325 147 0.016
cytoplasmic microtubule organization GO:0031122 22 0.016
positive regulation of hydrolase activity GO:0051345 78 0.016
Yeast
positive regulation of organelle organization GO:0010638 65 0.016
cellular response to endogenous stimulus GO:0071495 80 0.016
chemical homeostasis GO:0048878 92 0.016
lateral inhibition GO:0046331 206 0.016
cell growth GO:0016049 108 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
Yeast
dna metabolic process GO:0006259 227 0.015
Yeast
purine nucleoside catabolic process GO:0006152 112 0.015
Yeast
response to copper ion GO:0046688 4 0.015
regulation of transport GO:0051049 181 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
response to oxygen containing compound GO:1901700 200 0.015
tripartite regional subdivision GO:0007351 103 0.015
proton transport GO:0015992 7 0.015
ncrna metabolic process GO:0034660 43 0.015
single organism intracellular transport GO:1902582 207 0.015
Yeast Mouse
positive regulation of immune system process GO:0002684 68 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.014
Yeast
cellular homeostasis GO:0019725 80 0.014
ethanolamine containing compound metabolic process GO:0042439 4 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
Yeast
body morphogenesis GO:0010171 2 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
regulation of innate immune response GO:0045088 71 0.014
positive regulation of lipid biosynthetic process GO:0046889 3 0.014
regulation of defense response GO:0031347 102 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
taxis GO:0042330 304 0.013
sensory perception of sound GO:0007605 56 0.013
regulation of cell death GO:0010941 173 0.013
response to endogenous stimulus GO:0009719 119 0.013
sterol homeostasis GO:0055092 4 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
optokinetic behavior GO:0007634 3 0.013
protein localization to organelle GO:0033365 82 0.013
Yeast
posttranscriptional regulation of gene expression GO:0010608 145 0.013
cellular biogenic amine metabolic process GO:0006576 9 0.013
regulation of programmed cell death GO:0043067 152 0.013
purine containing compound metabolic process GO:0072521 155 0.013
Yeast
adult behavior GO:0030534 137 0.013
ribonucleoside monophosphate catabolic process GO:0009158 39 0.012
Yeast
ribonucleotide metabolic process GO:0009259 145 0.012
Yeast
regulation of purine nucleotide metabolic process GO:1900542 62 0.012
dna biosynthetic process GO:0071897 24 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
nucleoside monophosphate catabolic process GO:0009125 39 0.012
Yeast
translational termination GO:0006415 2 0.012
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.012
intracellular protein transmembrane import GO:0044743 4 0.012
Yeast
sulfur compound metabolic process GO:0006790 59 0.012
positive regulation of growth GO:0045927 75 0.012
macromolecular complex assembly GO:0065003 256 0.012
mitochondrial fission GO:0000266 8 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
Yeast
actin mediated cell contraction GO:0070252 21 0.011
cellular protein complex disassembly GO:0043624 35 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
Yeast
regulation of protein complex disassembly GO:0043244 29 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
regulation of mapk cascade GO:0043408 92 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
positive regulation of axonogenesis GO:0050772 2 0.011
kidney morphogenesis GO:0060993 3 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010
glial cell development GO:0021782 27 0.010
negative regulation of phosphate metabolic process GO:0045936 45 0.010
microvillus organization GO:0032528 4 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010

Hsc70-5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.053
disease of anatomical entity DOID:7 0 0.026
inherited metabolic disorder DOID:655 0 0.018
nervous system disease DOID:863 0 0.013