Drosophila melanogaster

0 known processes

Spn42De (Dmel_CG9460)

Serpin 42De

(Aliases: CG9460,Dmel\CG9460)

Spn42De biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.057
Fly
catabolic process GO:0009056 409 0.047
small molecule metabolic process GO:0044281 305 0.046
regionalization GO:0003002 416 0.045
endocytosis GO:0006897 310 0.042
response to abiotic stimulus GO:0009628 341 0.041
protein modification process GO:0036211 438 0.040
vesicle mediated transport GO:0016192 381 0.039
neurological system process GO:0050877 358 0.038
organic substance catabolic process GO:1901575 308 0.038
cellular protein modification process GO:0006464 438 0.038
negative regulation of gene expression GO:0010629 387 0.037
Rat Fly
defense response GO:0006952 300 0.035
Rat Fly
negative regulation of cellular metabolic process GO:0031324 382 0.034
Rat Fly
cellular catabolic process GO:0044248 372 0.034
kidney development GO:0001822 3 0.032
response to biotic stimulus GO:0009607 294 0.031
Fly
appendage development GO:0048736 401 0.031
steroid catabolic process GO:0006706 1 0.030
single organism behavior GO:0044708 391 0.030
regulation of multicellular organismal development GO:2000026 414 0.030
single organism catabolic process GO:0044712 228 0.029
response to external biotic stimulus GO:0043207 293 0.029
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.029
oxoacid metabolic process GO:0043436 103 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
carboxylic acid metabolic process GO:0019752 92 0.029
imaginal disc derived appendage development GO:0048737 399 0.029
wing disc morphogenesis GO:0007472 344 0.028
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.028
appendage morphogenesis GO:0035107 397 0.028
immune system process GO:0002376 347 0.028
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.027
body morphogenesis GO:0010171 2 0.027
compound eye development GO:0048749 307 0.027
anion homeostasis GO:0055081 3 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.026
response to organophosphorus GO:0046683 2 0.026
organic substance transport GO:0071702 257 0.026
cellular amino acid metabolic process GO:0006520 61 0.025
positive regulation of gene expression GO:0010628 290 0.025
sensory organ morphogenesis GO:0090596 260 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
phagocytosis GO:0006909 215 0.024
l amino acid import GO:0043092 2 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
eye development GO:0001654 323 0.024
phosphorylation GO:0016310 294 0.024
forebrain development GO:0030900 2 0.024
intracellular signal transduction GO:0035556 300 0.024
ion transport GO:0006811 145 0.024
organic acid metabolic process GO:0006082 103 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
compound eye morphogenesis GO:0001745 249 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
eye morphogenesis GO:0048592 260 0.023
benzene containing compound metabolic process GO:0042537 3 0.023
response to other organism GO:0051707 293 0.022
Fly
response to bacterium GO:0009617 198 0.022
Fly
hormone catabolic process GO:0042447 3 0.022
negative regulation of nucleic acid templated transcription GO:1903507 240 0.022
taxis GO:0042330 304 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.022
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.022
cell death GO:0008219 279 0.022
defense response to other organism GO:0098542 225 0.022
Fly
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
vitamin biosynthetic process GO:0009110 1 0.021
response to organic substance GO:0010033 284 0.021
lateral inhibition GO:0046331 206 0.021
camera type eye development GO:0043010 4 0.021
chemotaxis GO:0006935 249 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
positive regulation of signaling GO:0023056 243 0.021
positive regulation of cell communication GO:0010647 250 0.021
cellular ketone metabolic process GO:0042180 24 0.021
regulation of localization GO:0032879 275 0.021
tube development GO:0035295 244 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
salivary gland morphogenesis GO:0007435 145 0.020
death GO:0016265 284 0.020
response to radiation GO:0009314 155 0.020
polyol biosynthetic process GO:0046173 3 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
fat soluble vitamin biosynthetic process GO:0042362 1 0.020
gland development GO:0048732 191 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
single organism biosynthetic process GO:0044711 206 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
positive regulation of cell migration GO:0030335 2 0.019
regulation of response to stress GO:0080134 200 0.019
Rat
tube morphogenesis GO:0035239 191 0.019
multi organism behavior GO:0051705 175 0.019
gland morphogenesis GO:0022612 145 0.019
tissue morphogenesis GO:0048729 297 0.019
response to oxygen containing compound GO:1901700 200 0.019
negative regulation of signal transduction GO:0009968 206 0.019
Fly
epithelial cell development GO:0002064 274 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
exocrine system development GO:0035272 162 0.019
telencephalon development GO:0021537 2 0.019
response to lipopolysaccharide GO:0032496 4 0.019
sensory perception of chemical stimulus GO:0007606 116 0.019
immune response GO:0006955 246 0.018
Fly
nuclear division GO:0000280 332 0.018
proteolysis GO:0006508 192 0.018
Rat Fly
establishment of localization in cell GO:0051649 402 0.018
ras protein signal transduction GO:0007265 88 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
positive regulation of signal transduction GO:0009967 223 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
regulation of cell cycle GO:0051726 291 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
adult behavior GO:0030534 137 0.018
connective tissue development GO:0061448 3 0.018
protein localization GO:0008104 284 0.018
organelle fission GO:0048285 340 0.018
dorsal ventral pattern formation GO:0009953 133 0.018
spindle organization GO:0007051 253 0.018
growth GO:0040007 359 0.018
Rat
xenobiotic catabolic process GO:0042178 1 0.018
regulation of cell differentiation GO:0045595 302 0.018
salivary gland development GO:0007431 162 0.018
organophosphate metabolic process GO:0019637 195 0.018
epithelial cell differentiation GO:0030855 322 0.017
secondary metabolic process GO:0019748 75 0.017
organelle assembly GO:0070925 198 0.017
digestive tract development GO:0048565 149 0.017
immune response regulating signaling pathway GO:0002764 2 0.017
gene silencing GO:0016458 138 0.017
synaptic transmission GO:0007268 288 0.017
regulation of protein metabolic process GO:0051246 256 0.017
Rat Fly
regulation of molecular function GO:0065009 217 0.017
Rat Fly
positive regulation of cell motility GO:2000147 3 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
heterocycle catabolic process GO:0046700 166 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
homeostatic process GO:0042592 199 0.017
nucleotide metabolic process GO:0009117 161 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
Rat Fly
humoral immune response GO:0006959 117 0.017
Fly
axon guidance GO:0007411 233 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
response to mercury ion GO:0046689 3 0.016
regulation of immune system process GO:0002682 176 0.016
Fly
positive regulation of transcription dna templated GO:0045893 266 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
actin filament based process GO:0030029 220 0.016
digestive system development GO:0055123 149 0.016
programmed cell death GO:0012501 257 0.016
open tracheal system development GO:0007424 204 0.016
toxin catabolic process GO:0009407 1 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
leg disc development GO:0035218 92 0.016
immune response activating signal transduction GO:0002757 2 0.016
imaginal disc pattern formation GO:0007447 91 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
fat soluble vitamin metabolic process GO:0006775 1 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
amine metabolic process GO:0009308 12 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
Rat Fly
sensory perception GO:0007600 196 0.016
negative regulation of signaling GO:0023057 219 0.016
Fly
negative regulation of transcription dna templated GO:0045892 237 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
multi multicellular organism process GO:0044706 123 0.016
digestive tract morphogenesis GO:0048546 127 0.015
aging GO:0007568 143 0.015
developmental growth GO:0048589 280 0.015
Rat
toxin metabolic process GO:0009404 2 0.015
l glutamate import GO:0051938 1 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
chromosome organization GO:0051276 360 0.015
negative regulation of developmental process GO:0051093 201 0.015
pattern recognition receptor signaling pathway GO:0002221 2 0.015
macromolecule catabolic process GO:0009057 161 0.015
male gamete generation GO:0048232 201 0.015
ethanolamine containing compound metabolic process GO:0042439 4 0.015
cellular amine metabolic process GO:0044106 12 0.015
negative regulation of cell communication GO:0010648 223 0.015
Fly
defense response to gram negative bacterium GO:0050829 94 0.015
Fly
localization of cell GO:0051674 257 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
regulation of growth GO:0040008 233 0.015
activation of innate immune response GO:0002218 4 0.015
cell proliferation GO:0008283 299 0.015
medium chain fatty acid metabolic process GO:0051791 1 0.015
purine containing compound metabolic process GO:0072521 155 0.015
macromolecular complex assembly GO:0065003 256 0.015
axis specification GO:0009798 167 0.015
segmentation GO:0035282 207 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.014
spermatogenesis GO:0007283 200 0.014
phosphate ion transport GO:0006817 4 0.014
axonogenesis GO:0007409 290 0.014
multicellular organismal aging GO:0010259 140 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
mitotic nuclear division GO:0007067 213 0.014
response to monosaccharide GO:0034284 4 0.014
cellular macromolecule localization GO:0070727 220 0.014
limb development GO:0060173 1 0.014
innate immune response activating signal transduction GO:0002758 2 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
response to glucose GO:0009749 2 0.014
protein phosphorylation GO:0006468 169 0.014
single organism intracellular transport GO:1902582 207 0.014
response to extracellular stimulus GO:0009991 116 0.014
Rat
rna processing GO:0006396 147 0.014
multicellular organismal reproductive behavior GO:0033057 110 0.014
reproductive behavior GO:0019098 122 0.014
regulation of cell death GO:0010941 173 0.014
response to light stimulus GO:0009416 124 0.014
innate immune response GO:0045087 144 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
wnt signaling pathway GO:0016055 98 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
regulation of developmental growth GO:0048638 174 0.014
axon development GO:0061564 297 0.014
respiratory system development GO:0060541 213 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
response to alcohol GO:0097305 95 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
regulation of catabolic process GO:0009894 170 0.013
sensory perception of smell GO:0007608 80 0.013
regulation of catalytic activity GO:0050790 185 0.013
Rat Fly
purine ribonucleoside metabolic process GO:0046128 127 0.013
cellular lipid metabolic process GO:0044255 83 0.013
chromosome segregation GO:0007059 157 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
detection of stimulus GO:0051606 156 0.013
insecticide catabolic process GO:0046701 1 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
aromatic compound catabolic process GO:0019439 166 0.013
response to hexose GO:0009746 3 0.013
blastoderm segmentation GO:0007350 159 0.013
regulation of immune response GO:0050776 118 0.013
Fly
muscle structure development GO:0061061 224 0.013
cellular homeostasis GO:0019725 80 0.013
neuron projection guidance GO:0097485 241 0.013
regulation of organelle organization GO:0033043 196 0.013
mating GO:0007618 120 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.013
nucleoside metabolic process GO:0009116 127 0.013
regulation of cell development GO:0060284 215 0.013
estrogen metabolic process GO:0008210 1 0.013
regulation of transport GO:0051049 181 0.013
cellular response to ethanol GO:0071361 4 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
regulation of anatomical structure size GO:0090066 163 0.013
regulation of programmed cell death GO:0043067 152 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
defense response to bacterium GO:0042742 178 0.013
Fly
regulation of multi organism process GO:0043900 131 0.013
Fly
organophosphate catabolic process GO:0046434 112 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
regulation of response to external stimulus GO:0032101 115 0.013
Rat Fly
secondary metabolite catabolic process GO:0090487 1 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
sterol homeostasis GO:0055092 4 0.013
actin cytoskeleton organization GO:0030036 206 0.013
dendrite development GO:0016358 204 0.012
sodium dependent phosphate transport GO:0044341 2 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
limb morphogenesis GO:0035108 1 0.012
lauric acid metabolic process GO:0048252 1 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
wing disc pattern formation GO:0035222 66 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
dendrite morphogenesis GO:0048813 199 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
cell motility GO:0048870 251 0.012
mating behavior GO:0007617 106 0.012
cell migration GO:0016477 238 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
wound healing GO:0042060 75 0.012
Rat
peptide metabolic process GO:0006518 80 0.012
Fly
purine nucleoside metabolic process GO:0042278 127 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.012
carbohydrate metabolic process GO:0005975 82 0.012
retina development in camera type eye GO:0060041 4 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
mitotic spindle organization GO:0007052 220 0.012
cholesterol homeostasis GO:0042632 3 0.012
regulation of cell cycle process GO:0010564 181 0.012
nucleoside catabolic process GO:0009164 112 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
response to nutrient levels GO:0031667 114 0.012
Rat
hindbrain development GO:0030902 2 0.012
regulation of hydrolase activity GO:0051336 97 0.012
Rat Fly
response to ethanol GO:0045471 59 0.012
lipid metabolic process GO:0006629 121 0.012
nucleotide catabolic process GO:0009166 109 0.012
apoptotic process GO:0006915 159 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
central nervous system development GO:0007417 201 0.011
regulation of nervous system development GO:0051960 248 0.011
nephron development GO:0072006 3 0.011
intracellular transport GO:0046907 228 0.011
monocarboxylic acid transport GO:0015718 3 0.011
vitamin metabolic process GO:0006766 2 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
developmental programmed cell death GO:0010623 138 0.011
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
leg disc morphogenesis GO:0007478 80 0.011
antimicrobial humoral response GO:0019730 99 0.011
Fly
embryonic pattern specification GO:0009880 174 0.011
response to copper ion GO:0046688 4 0.011
salivary gland histolysis GO:0035070 88 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
behavioral response to ethanol GO:0048149 49 0.011
single organism cellular localization GO:1902580 180 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
histolysis GO:0007559 102 0.011
cation transport GO:0006812 110 0.011
muscle organ development GO:0007517 127 0.011
positive regulation of molecular function GO:0044093 136 0.011
ameboidal type cell migration GO:0001667 151 0.011
locomotory behavior GO:0007626 176 0.011
response to temperature stimulus GO:0009266 106 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
embryonic morphogenesis GO:0048598 206 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
purine containing compound catabolic process GO:0072523 112 0.011
protein transport GO:0015031 155 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
neurotransmitter metabolic process GO:0042133 2 0.011
biological adhesion GO:0022610 138 0.011
Rat
multi organism reproductive behavior GO:0044705 121 0.011
establishment of protein localization GO:0045184 163 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
notch signaling pathway GO:0007219 120 0.011
cellular protein localization GO:0034613 160 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
positive regulation of catabolic process GO:0009896 105 0.011
aggressive behavior GO:0002118 63 0.011
kidney epithelium development GO:0072073 3 0.011
determination of adult lifespan GO:0008340 137 0.011
androgen metabolic process GO:0008209 1 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
ovarian follicle cell development GO:0030707 248 0.011
endomembrane system organization GO:0010256 119 0.011
transmembrane transport GO:0055085 139 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
response to nitrogen compound GO:1901698 90 0.011
regulation of lipid transport GO:0032368 3 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
mesenchymal cell development GO:0014031 1 0.011
camera type eye morphogenesis GO:0048593 2 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
chaeta development GO:0022416 97 0.011
mapk cascade GO:0000165 107 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
developmental maturation GO:0021700 172 0.011
cell cycle phase transition GO:0044770 140 0.011
cell adhesion GO:0007155 136 0.011
Rat
regulation of gene expression epigenetic GO:0040029 128 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
anterior posterior pattern specification GO:0009952 136 0.011
nitrogen compound transport GO:0071705 85 0.011
protein complex biogenesis GO:0070271 201 0.011
regulation of defense response GO:0031347 102 0.011
Rat
tissue death GO:0016271 102 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
cellularization GO:0007349 90 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
cellular amide metabolic process GO:0043603 80 0.011
Fly
synapse assembly GO:0007416 143 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
acetate ester metabolic process GO:1900619 2 0.010
protein maturation GO:0051604 71 0.010
Fly
cytoplasmic transport GO:0016482 130 0.010
protein processing GO:0016485 68 0.010
Fly
kidney morphogenesis GO:0060993 3 0.010
autophagic cell death GO:0048102 83 0.010
chemical homeostasis GO:0048878 92 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
Rat Fly
regulation of organ morphogenesis GO:2000027 78 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
response to organic cyclic compound GO:0014070 89 0.010
regulation of phosphorylation GO:0042325 147 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
response to wounding GO:0009611 94 0.010
Rat
triglyceride biosynthetic process GO:0019432 2 0.010
acetylcholine metabolic process GO:0008291 2 0.010

Spn42De disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
cardiovascular system disease DOID:1287 0 0.024
nervous system disease DOID:863 0 0.021
hypertension DOID:10763 0 0.020
artery disease DOID:0050828 0 0.020
vascular disease DOID:178 0 0.020
disease of metabolism DOID:0014667 0 0.018
renal tubular transport disease DOID:447 0 0.015
kidney disease DOID:557 0 0.015
urinary system disease DOID:18 0 0.015
inherited metabolic disorder DOID:655 0 0.014
essential hypertension DOID:10825 0 0.014
musculoskeletal system disease DOID:17 0 0.011
sensory system disease DOID:0050155 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
glucose metabolism disease DOID:4194 0 0.011
acquired metabolic disease DOID:0060158 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
central nervous system disease DOID:331 0 0.010
cancer DOID:162 0 0.010