Drosophila melanogaster

42 known processes

dpa (Dmel_CG1616)

disc proliferation abnormal

(Aliases: DmMcm4,Dpa,l(2)43Ca,MCM4_DROME,43Ca,DmMCM4,mcm4,MCM4,DmeMCM4,Dmel\CG1616,CG1616,Mcm4)

dpa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear dna replication GO:0033260 1 0.956
Yeast
mitotic nuclear division GO:0007067 213 0.880
sister chromatid segregation GO:0000819 92 0.858
cell cycle dna replication GO:0044786 23 0.824
Yeast
chromosome organization GO:0051276 360 0.817
dna replication initiation GO:0006270 6 0.806
Yeast
chromosome condensation GO:0030261 41 0.793
mitotic spindle organization GO:0007052 220 0.782
organelle fission GO:0048285 340 0.762
nuclear division GO:0000280 332 0.740
spindle assembly GO:0051225 80 0.737
dna metabolic process GO:0006259 227 0.728
spindle organization GO:0007051 253 0.727
mitotic sister chromatid segregation GO:0000070 87 0.717
dna replication GO:0006260 48 0.640
chromosome segregation GO:0007059 157 0.630
spindle assembly involved in mitosis GO:0090307 50 0.610
dna packaging GO:0006323 91 0.608
mitotic chromosome condensation GO:0007076 22 0.598
protein complex assembly GO:0006461 200 0.411
dna conformation change GO:0071103 105 0.393
organelle assembly GO:0070925 198 0.385
macromolecular complex assembly GO:0065003 256 0.370
Yeast
cellular macromolecular complex assembly GO:0034622 153 0.322
Yeast
mitotic sister chromatid separation GO:0051306 30 0.320
spindle midzone assembly GO:0051255 4 0.302
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.288
meiotic cell cycle process GO:1903046 132 0.281
cellular protein complex assembly GO:0043623 71 0.271
protein complex biogenesis GO:0070271 201 0.259
regulation of mitotic spindle organization GO:0060236 9 0.255
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 8 0.252
telomere capping GO:0016233 11 0.226
microtubule organizing center organization GO:0031023 168 0.222
organelle localization GO:0051640 148 0.220
dna dependent dna replication GO:0006261 17 0.208
Yeast Mouse
regulation of cytoskeleton organization GO:0051493 89 0.205
mitotic spindle elongation GO:0000022 81 0.201
pronuclear migration GO:0035046 4 0.173
regulation of mitosis GO:0007088 56 0.168
regulation of cell cycle GO:0051726 291 0.155
regulation of microtubule cytoskeleton organization GO:0070507 41 0.151
regulation of mitotic cell cycle GO:0007346 190 0.136
dna endoreduplication GO:0042023 22 0.130
mitotic sister chromatid cohesion GO:0007064 6 0.091
single organism biosynthetic process GO:0044711 206 0.091
Yeast
regulation of microtubule based process GO:0032886 49 0.086
spindle assembly involved in meiosis GO:0090306 20 0.083
meiosis i GO:0007127 59 0.082
centrosome organization GO:0051297 163 0.080
centrosome cycle GO:0007098 137 0.079
sensory organ morphogenesis GO:0090596 260 0.076
single organism membrane organization GO:0044802 93 0.075
protein dna complex assembly GO:0065004 63 0.073
Yeast
g2 m transition of mitotic cell cycle GO:0000086 19 0.073
meiotic spindle organization GO:0000212 36 0.072
establishment of chromosome localization GO:0051303 20 0.065
metaphase plate congression GO:0051310 19 0.063
cell cycle phase transition GO:0044770 140 0.060
regulation of cell division GO:0051302 72 0.058
male meiosis GO:0007140 52 0.056
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.056
female meiotic division GO:0007143 70 0.052
catabolic process GO:0009056 409 0.052
Human Yeast
maintenance of location GO:0051235 73 0.050
determination of adult lifespan GO:0008340 137 0.049
single organism cellular localization GO:1902580 180 0.048
mitotic cytokinesis GO:0000281 50 0.047
microtubule polymerization or depolymerization GO:0031109 39 0.047
eye development GO:0001654 323 0.046
nuclear migration GO:0007097 20 0.045
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.045
mitotic spindle stabilization GO:0043148 6 0.044
regulation of mitotic sister chromatid separation GO:0010965 28 0.044
multicellular organismal aging GO:0010259 140 0.043
protein localization GO:0008104 284 0.043
chromatin modification GO:0016568 147 0.043
embryo development ending in birth or egg hatching GO:0009792 152 0.043
Worm
cellular protein localization GO:0034613 160 0.041
regulation of catabolic process GO:0009894 170 0.041
cell proliferation GO:0008283 299 0.041
body morphogenesis GO:0010171 2 0.040
protein complex disassembly GO:0043241 36 0.040
negative regulation of organelle organization GO:0010639 56 0.039
cytokinesis GO:0000910 90 0.039
membrane organization GO:0061024 112 0.039
Worm
protein dna complex subunit organization GO:0071824 86 0.038
Yeast
regulation of localization GO:0032879 275 0.037
regulation of cell differentiation GO:0045595 302 0.035
spindle elongation GO:0051231 83 0.035
regulation of cell cycle process GO:0010564 181 0.034
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.034
mitotic metaphase plate congression GO:0007080 13 0.034
reproductive system development GO:0061458 74 0.034
protein transport GO:0015031 155 0.033
protein polymerization GO:0051258 42 0.033
dna geometric change GO:0032392 16 0.032
regulation of chromosome segregation GO:0051983 32 0.032
cell cell signaling involved in cell fate commitment GO:0045168 210 0.032
positive regulation of hydrolase activity GO:0051345 78 0.031
translesion synthesis GO:0019985 2 0.031
regulation of protein depolymerization GO:1901879 27 0.031
negative regulation of gene expression GO:0010629 387 0.030
cellular macromolecule catabolic process GO:0044265 136 0.029
camera type eye morphogenesis GO:0048593 2 0.029
metaphase anaphase transition of cell cycle GO:0044784 28 0.029
single organism intracellular transport GO:1902582 207 0.029
regulation of mitotic sister chromatid segregation GO:0033047 28 0.029
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
macromolecular complex disassembly GO:0032984 37 0.028
cellular protein modification process GO:0006464 438 0.027
negative regulation of mitotic cell cycle GO:0045930 109 0.027
small molecule metabolic process GO:0044281 305 0.026
Human Yeast
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.026
lateral inhibition GO:0046331 206 0.025
endomembrane system organization GO:0010256 119 0.025
regulation of molecular function GO:0065009 217 0.025
microtubule anchoring GO:0034453 11 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
protein modification process GO:0036211 438 0.024
regulation of mitotic spindle elongation GO:0032888 1 0.024
regulation of mitotic cell cycle phase transition GO:1901990 130 0.024
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.024
cellular catabolic process GO:0044248 372 0.024
Human Yeast
negative regulation of cytoskeleton organization GO:0051494 30 0.024
chromatin organization GO:0006325 207 0.024
vesicle mediated transport GO:0016192 381 0.024
Worm
reproductive structure development GO:0048608 74 0.023
centrosome separation GO:0051299 20 0.023
organonitrogen compound metabolic process GO:1901564 318 0.023
Human Yeast
positive regulation of catalytic activity GO:0043085 118 0.023
regulation of cell development GO:0060284 215 0.022
macromolecule catabolic process GO:0009057 161 0.022
maintenance of protein location in cell GO:0032507 26 0.022
histone mrna metabolic process GO:0008334 8 0.022
tube development GO:0035295 244 0.022
development of primary sexual characteristics GO:0045137 50 0.022
establishment of organelle localization GO:0051656 122 0.022
aromatic compound catabolic process GO:0019439 166 0.021
Human Yeast
sex differentiation GO:0007548 81 0.021
heterocycle catabolic process GO:0046700 166 0.021
Human Yeast
dna amplification GO:0006277 11 0.021
postreplication repair GO:0006301 2 0.021
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.021
negative regulation of rna biosynthetic process GO:1902679 240 0.020
oxoacid metabolic process GO:0043436 103 0.020
microtubule based movement GO:0007018 51 0.020
negative regulation of cell cycle GO:0045786 116 0.020
regulation of catalytic activity GO:0050790 185 0.020
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.019
cell migration GO:0016477 238 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
positive regulation of developmental process GO:0051094 143 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
modification dependent macromolecule catabolic process GO:0043632 79 0.018
histone modification GO:0016570 106 0.018
negative regulation of cellular component organization GO:0051129 108 0.018
female meiosis i GO:0007144 8 0.018
mitotic dna replication checkpoint GO:0033314 5 0.017
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.017
humoral immune response GO:0006959 117 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
Human Yeast
regulation of cellular component biogenesis GO:0044087 201 0.017
mitotic cell cycle embryonic GO:0045448 38 0.017
establishment of meiotic spindle localization GO:0051295 3 0.017
negative regulation of purine nucleotide catabolic process GO:0033122 1 0.017
regulation of protein metabolic process GO:0051246 256 0.016
compound eye development GO:0048749 307 0.016
protein catabolic process GO:0030163 101 0.016
organic acid metabolic process GO:0006082 103 0.016
protein maturation GO:0051604 71 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
gonad development GO:0008406 50 0.016
establishment of localization in cell GO:0051649 402 0.015
gene silencing GO:0016458 138 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
aging GO:0007568 143 0.015
meiotic chromosome segregation GO:0045132 59 0.014
cellular protein complex disassembly GO:0043624 35 0.014
regulation of protein catabolic process GO:0042176 55 0.014
single organism catabolic process GO:0044712 228 0.014
Human Yeast
negative regulation of mitotic metaphase anaphase transition GO:0045841 13 0.014
distributive segregation GO:0032837 6 0.014
modification dependent protein catabolic process GO:0019941 78 0.013
establishment of cell polarity GO:0030010 40 0.013
regulation of protein complex assembly GO:0043254 42 0.013
covalent chromatin modification GO:0016569 106 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
regulation of spindle organization GO:0090224 17 0.013
ubiquitin dependent protein catabolic process GO:0006511 78 0.013
intracellular protein transport GO:0006886 104 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
Human Yeast
response to light stimulus GO:0009416 124 0.013
proteolysis GO:0006508 192 0.013
organic substance catabolic process GO:1901575 308 0.012
Human Yeast
regulation of nucleoside metabolic process GO:0009118 50 0.012
positive regulation of cell development GO:0010720 61 0.012
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.012
ovarian fusome organization GO:0030723 11 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of protein localization GO:0032880 76 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
Human Yeast
heart development GO:0007507 82 0.012
positive regulation of mitotic cell cycle GO:0045931 34 0.012
dephosphorylation GO:0016311 51 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
negative regulation of cellular catabolic process GO:0031330 34 0.012
gland development GO:0048732 191 0.012
regulation of neurogenesis GO:0050767 158 0.012
establishment of protein localization GO:0045184 163 0.012
protein depolymerization GO:0051261 31 0.012
embryonic organ development GO:0048568 50 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
protein processing GO:0016485 68 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
positive regulation of cell proliferation GO:0008284 47 0.011
axon development GO:0061564 297 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
Yeast
regulation of cell cycle phase transition GO:1901987 130 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
centrosome duplication GO:0051298 121 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
cardiovascular system development GO:0072358 82 0.011
immune response GO:0006955 246 0.011
regulation of organelle organization GO:0033043 196 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
Human Yeast
carboxylic acid metabolic process GO:0019752 92 0.010
positive regulation of cell cycle GO:0045787 43 0.010
mitotic spindle midzone assembly GO:0051256 1 0.010
positive regulation of response to stimulus GO:0048584 323 0.010
cellular protein catabolic process GO:0044257 83 0.010
double strand break repair via homologous recombination GO:0000724 13 0.010
Yeast

dpa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.010