Drosophila melanogaster

14 known processes

CG11876 (Dmel_CG11876)

CG11876 gene product from transcript CG11876-RA

(Aliases: Dmel\CG11876,PDHB,E1beta)

CG11876 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleotide metabolic process GO:0009117 161 0.632
nucleobase containing small molecule metabolic process GO:0055086 174 0.607
single organism biosynthetic process GO:0044711 206 0.527
Human Yeast Rat
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.524
mitochondrion organization GO:0007005 65 0.515
small molecule metabolic process GO:0044281 305 0.505
Human Yeast Rat
organophosphate metabolic process GO:0019637 195 0.459
atp metabolic process GO:0046034 49 0.427
purine nucleoside monophosphate metabolic process GO:0009126 50 0.403
organonitrogen compound metabolic process GO:1901564 318 0.399
ribose phosphate metabolic process GO:0019693 145 0.370
nucleoside triphosphate metabolic process GO:0009141 120 0.352
carbohydrate derivative metabolic process GO:1901135 217 0.346
ribonucleoside monophosphate metabolic process GO:0009161 51 0.318
glycosyl compound metabolic process GO:1901657 127 0.302
nucleoside phosphate metabolic process GO:0006753 162 0.294
ribonucleotide metabolic process GO:0009259 145 0.292
purine nucleoside metabolic process GO:0042278 127 0.283
ribonucleoside metabolic process GO:0009119 127 0.273
ribose phosphate biosynthetic process GO:0046390 28 0.254
nucleoside monophosphate metabolic process GO:0009123 52 0.251
purine nucleotide metabolic process GO:0006163 146 0.206
purine containing compound biosynthetic process GO:0072522 30 0.186
membrane organization GO:0061024 112 0.180
ribonucleoside triphosphate metabolic process GO:0009199 119 0.173
purine containing compound metabolic process GO:0072521 155 0.172
cellular respiration GO:0045333 26 0.156
Human
purine ribonucleoside metabolic process GO:0046128 127 0.153
monocarboxylic acid metabolic process GO:0032787 29 0.150
Human Yeast Rat
nicotinamide nucleotide metabolic process GO:0046496 2 0.149
purine ribonucleotide biosynthetic process GO:0009152 28 0.147
organonitrogen compound biosynthetic process GO:1901566 117 0.140
nucleoside metabolic process GO:0009116 127 0.130
establishment of localization in cell GO:0051649 402 0.120
organophosphate biosynthetic process GO:0090407 46 0.116
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.114
purine ribonucleotide metabolic process GO:0009150 145 0.103
atp biosynthetic process GO:0006754 2 0.101
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.092
organic acid metabolic process GO:0006082 103 0.092
Human Yeast Rat
carbohydrate derivative biosynthetic process GO:1901137 85 0.091
catabolic process GO:0009056 409 0.086
exocrine system development GO:0035272 162 0.086
transmembrane transport GO:0055085 139 0.085
purine nucleoside triphosphate metabolic process GO:0009144 119 0.084
negative regulation of biosynthetic process GO:0009890 277 0.083
ribonucleoside biosynthetic process GO:0042455 3 0.080
single organism membrane organization GO:0044802 93 0.077
response to abiotic stimulus GO:0009628 341 0.073
gland development GO:0048732 191 0.073
generation of precursor metabolites and energy GO:0006091 42 0.072
Human
regulation of protein metabolic process GO:0051246 256 0.070
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.069
cell death GO:0008219 279 0.067
purine nucleotide biosynthetic process GO:0006164 29 0.065
oxidation reduction process GO:0055114 123 0.063
Human Yeast Rat
oxoacid metabolic process GO:0043436 103 0.060
Human Yeast Rat
pyridine nucleotide metabolic process GO:0019362 2 0.060
aging GO:0007568 143 0.059
carboxylic acid metabolic process GO:0019752 92 0.056
Human Yeast Rat
nucleoside phosphate biosynthetic process GO:1901293 34 0.054
intracellular transport GO:0046907 228 0.054
embryo development ending in birth or egg hatching GO:0009792 152 0.052
regulation of cellular protein metabolic process GO:0032268 243 0.052
protein complex assembly GO:0006461 200 0.051
response to organic substance GO:0010033 284 0.048
energy derivation by oxidation of organic compounds GO:0015980 32 0.048
Human
tube morphogenesis GO:0035239 191 0.048
central nervous system development GO:0007417 201 0.047
regulation of organelle organization GO:0033043 196 0.047
pyridine containing compound metabolic process GO:0072524 3 0.046
ion transport GO:0006811 145 0.045
ion transmembrane transport GO:0034220 122 0.044
oxidoreduction coenzyme metabolic process GO:0006733 2 0.044
cell division GO:0051301 248 0.044
glycosyl compound biosynthetic process GO:1901659 3 0.044
nucleotide biosynthetic process GO:0009165 34 0.044
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.043
regulation of molecular function GO:0065009 217 0.043
thioester metabolic process GO:0035383 3 0.042
Human Yeast Rat
acyl coa biosynthetic process GO:0071616 2 0.042
Human Yeast Rat
developmental programmed cell death GO:0010623 138 0.042
purine ribonucleoside biosynthetic process GO:0046129 3 0.042
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.041
protein complex biogenesis GO:0070271 201 0.040
negative regulation of cellular metabolic process GO:0031324 382 0.040
ribonucleotide biosynthetic process GO:0009260 28 0.040
negative regulation of gene expression GO:0010629 387 0.039
cellular catabolic process GO:0044248 372 0.038
death GO:0016265 284 0.038
determination of adult lifespan GO:0008340 137 0.037
organic substance catabolic process GO:1901575 308 0.037
larval development GO:0002164 104 0.037
negative regulation of developmental process GO:0051093 201 0.036
salivary gland development GO:0007431 162 0.035
vesicle mediated transport GO:0016192 381 0.035
negative regulation of cellular biosynthetic process GO:0031327 277 0.034
gland morphogenesis GO:0022612 145 0.033
tricarboxylic acid metabolic process GO:0072350 1 0.033
cation transport GO:0006812 110 0.032
intracellular signal transduction GO:0035556 300 0.032
histolysis GO:0007559 102 0.032
immune response GO:0006955 246 0.031
single organism catabolic process GO:0044712 228 0.031
reactive oxygen species metabolic process GO:0072593 22 0.030
regulation of cell cycle phase transition GO:1901987 130 0.030
pyruvate metabolic process GO:0006090 7 0.030
Human Yeast Rat
growth GO:0040007 359 0.029
regulation of catalytic activity GO:0050790 185 0.029
regulation of catabolic process GO:0009894 170 0.029
salivary gland morphogenesis GO:0007435 145 0.029
phosphorylation GO:0016310 294 0.028
negative regulation of cellular protein metabolic process GO:0032269 85 0.028
positive regulation of molecular function GO:0044093 136 0.027
cellular response to organic substance GO:0071310 132 0.027
multicellular organismal aging GO:0010259 140 0.025
electron transport chain GO:0022900 14 0.025
macromolecular complex assembly GO:0065003 256 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
programmed cell death GO:0012501 257 0.024
negative regulation of cellular component organization GO:0051129 108 0.024
atp synthesis coupled electron transport GO:0042773 8 0.023
detection of light stimulus GO:0009583 58 0.023
cellular component assembly involved in morphogenesis GO:0010927 151 0.023
nucleoside triphosphate biosynthetic process GO:0009142 2 0.022
spermatogenesis GO:0007283 200 0.022
cell growth GO:0016049 108 0.021
single organism membrane fusion GO:0044801 42 0.021
single organism behavior GO:0044708 391 0.020
negative regulation of multicellular organismal process GO:0051241 142 0.020
brain development GO:0007420 120 0.020
positive regulation of signaling GO:0023056 243 0.019
head development GO:0060322 135 0.019
proteolysis GO:0006508 192 0.018
inorganic cation transmembrane transport GO:0098662 61 0.018
respiratory electron transport chain GO:0022904 11 0.017
lipid biosynthetic process GO:0008610 46 0.017
cation transmembrane transport GO:0098655 88 0.017
organic substance transport GO:0071702 257 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
oxidative phosphorylation GO:0006119 9 0.017
nucleoside monophosphate biosynthetic process GO:0009124 4 0.017
negative regulation of protein metabolic process GO:0051248 85 0.017
chromosome organization GO:0051276 360 0.016
regulation of cell death GO:0010941 173 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
regulation of proteolysis GO:0030162 87 0.016
acyl coa metabolic process GO:0006637 3 0.016
Human Yeast Rat
actin cytoskeleton organization GO:0030036 206 0.016
organic cyclic compound catabolic process GO:1901361 168 0.015
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
lipid metabolic process GO:0006629 121 0.015
phagocytosis GO:0006909 215 0.015
secretion by cell GO:0032940 101 0.015
single organism cellular localization GO:1902580 180 0.015
response to organic cyclic compound GO:0014070 89 0.015
chromosome separation GO:0051304 42 0.015
regionalization GO:0003002 416 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
mitotic spindle organization GO:0007052 220 0.015
chromatin organization GO:0006325 207 0.015
monovalent inorganic cation transport GO:0015672 40 0.015
endocytosis GO:0006897 310 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
regulation of cell differentiation GO:0045595 302 0.014
eggshell chorion assembly GO:0007306 66 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.014
response to extracellular stimulus GO:0009991 116 0.014
protein transport GO:0015031 155 0.014
negative regulation of growth GO:0045926 84 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
actin filament based process GO:0030029 220 0.014
cell proliferation GO:0008283 299 0.014
citrate metabolic process GO:0006101 0 0.013
single organism intracellular transport GO:1902582 207 0.013
mitochondrial fusion GO:0008053 7 0.013
small molecule biosynthetic process GO:0044283 37 0.013
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.013
cytoplasmic microtubule organization GO:0031122 22 0.013
negative regulation of cell proliferation GO:0008285 69 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.013
sensory perception GO:0007600 196 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
synaptic transmission GO:0007268 288 0.013
response to radiation GO:0009314 155 0.012
response to organophosphorus GO:0046683 2 0.012
cellular protein complex assembly GO:0043623 71 0.012
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.012
purine containing compound catabolic process GO:0072523 112 0.012
male gamete generation GO:0048232 201 0.012
negative regulation of signaling GO:0023057 219 0.012
urogenital system development GO:0001655 72 0.012
epithelial tube morphogenesis GO:0060562 88 0.012
mitotic nuclear division GO:0007067 213 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.011
regulation of growth GO:0040008 233 0.011
regulation of membrane potential GO:0042391 35 0.011
positive regulation of cell communication GO:0010647 250 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
nucleoside biosynthetic process GO:0009163 3 0.011
regulation of apoptotic process GO:0042981 130 0.011
organophosphate catabolic process GO:0046434 112 0.011
kidney development GO:0001822 3 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
protein processing GO:0016485 68 0.011
response to nutrient levels GO:0031667 114 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
neuroblast proliferation GO:0007405 74 0.011
response to hypoxia GO:0001666 53 0.011
regulation of programmed cell death GO:0043067 152 0.011
renal system development GO:0072001 72 0.011
mitochondrial atp synthesis coupled electron transport GO:0042775 8 0.010
positive regulation of response to stimulus GO:0048584 323 0.010
chaeta development GO:0022416 97 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
negative regulation of response to stimulus GO:0048585 258 0.010
response to oxygen containing compound GO:1901700 200 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
cellular ketone metabolic process GO:0042180 24 0.010
positive regulation of viral process GO:0048524 2 0.010

CG11876 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
disease of cellular proliferation DOID:14566 0 0.038
cancer DOID:162 0 0.034
organ system cancer DOID:0050686 0 0.034
disease of metabolism DOID:0014667 0 0.029
nervous system disease DOID:863 0 0.026
inherited metabolic disorder DOID:655 0 0.018
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010