Drosophila melanogaster

0 known processes

TM4SF (Dmel_CG11303)

Transmembrane 4 superfamily

(Aliases: Dm.Tsp60A,Dmel\CG11303,CG11303)

TM4SF biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 136 0.187
response to organic substance GO:0010033 284 0.064
neurological system process GO:0050877 358 0.062
neurotransmitter metabolic process GO:0042133 2 0.056
small molecule metabolic process GO:0044281 305 0.050
acetate ester metabolic process GO:1900619 2 0.047
cation transport GO:0006812 110 0.045
response to abiotic stimulus GO:0009628 341 0.043
organonitrogen compound metabolic process GO:1901564 318 0.042
salt aversion GO:0035199 3 0.041
mating GO:0007618 120 0.038
vesicle mediated transport GO:0016192 381 0.037
single organism behavior GO:0044708 391 0.037
positive regulation of signaling GO:0023056 243 0.033
Human
regulation of multicellular organismal development GO:2000026 414 0.031
nucleobase containing small molecule metabolic process GO:0055086 174 0.030
detection of abiotic stimulus GO:0009582 66 0.030
establishment of localization in cell GO:0051649 402 0.029
acetylcholine metabolic process GO:0008291 2 0.028
ribose phosphate metabolic process GO:0019693 145 0.028
response to oxygen containing compound GO:1901700 200 0.028
intracellular signal transduction GO:0035556 300 0.028
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
catabolic process GO:0009056 409 0.028
negative regulation of cell communication GO:0010648 223 0.028
Human
regulation of catalytic activity GO:0050790 185 0.028
purine containing compound metabolic process GO:0072521 155 0.027
compound eye development GO:0048749 307 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
protein modification process GO:0036211 438 0.026
regulation of protein metabolic process GO:0051246 256 0.026
ion transport GO:0006811 145 0.026
detection of stimulus GO:0051606 156 0.025
nucleotide metabolic process GO:0009117 161 0.025
actin filament based process GO:0030029 220 0.025
single organism catabolic process GO:0044712 228 0.025
carboxylic acid metabolic process GO:0019752 92 0.024
sensory perception of salty taste GO:0050914 3 0.024
regulation of molecular function GO:0065009 217 0.024
negative regulation of signaling GO:0023057 219 0.024
Human
organophosphate metabolic process GO:0019637 195 0.024
sensory perception GO:0007600 196 0.024
endocytosis GO:0006897 310 0.023
neuropeptide signaling pathway GO:0007218 45 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.023
body morphogenesis GO:0010171 2 0.022
detection of light stimulus GO:0009583 58 0.022
phagocytosis GO:0006909 215 0.022
positive regulation of cell communication GO:0010647 250 0.022
Human
cation transmembrane transport GO:0098655 88 0.022
adult behavior GO:0030534 137 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
Human
regionalization GO:0003002 416 0.022
positive regulation of catalytic activity GO:0043085 118 0.022
inter male aggressive behavior GO:0002121 60 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
Human
behavioral response to ethanol GO:0048149 49 0.021
ribonucleoside catabolic process GO:0042454 112 0.021
response to ethanol GO:0045471 59 0.021
cognition GO:0050890 141 0.020
oxoacid metabolic process GO:0043436 103 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
organic substance catabolic process GO:1901575 308 0.020
defense response GO:0006952 300 0.020
Human
organic acid metabolic process GO:0006082 103 0.020
respiratory system development GO:0060541 213 0.020
positive regulation of molecular function GO:0044093 136 0.020
actin cytoskeleton organization GO:0030036 206 0.020
glycosyl compound catabolic process GO:1901658 112 0.019
detection of external stimulus GO:0009581 66 0.019
amine metabolic process GO:0009308 12 0.019
purine containing compound catabolic process GO:0072523 112 0.019
positive regulation of signal transduction GO:0009967 223 0.019
Human
negative regulation of multicellular organismal process GO:0051241 142 0.019
response to other organism GO:0051707 293 0.019
Human
neuron recognition GO:0008038 101 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
cellular amine metabolic process GO:0044106 12 0.019
camera type eye development GO:0043010 4 0.019
cell recognition GO:0008037 102 0.019
nucleoside phosphate metabolic process GO:0006753 162 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
response to external biotic stimulus GO:0043207 293 0.018
Human
death GO:0016265 284 0.018
negative regulation of signal transduction GO:0009968 206 0.018
Human
organic substance transport GO:0071702 257 0.018
cell motility GO:0048870 251 0.018
sensory perception of taste GO:0050909 25 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
ras protein signal transduction GO:0007265 88 0.018
eye morphogenesis GO:0048592 260 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.018
cell proliferation GO:0008283 299 0.018
response to radiation GO:0009314 155 0.018
multi organism reproductive behavior GO:0044705 121 0.018
heterocycle catabolic process GO:0046700 166 0.018
sensory perception of chemical stimulus GO:0007606 116 0.018
proteolysis GO:0006508 192 0.018
positive regulation of phosphate metabolic process GO:0045937 139 0.018
taxis GO:0042330 304 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
eye development GO:0001654 323 0.017
aggressive behavior GO:0002118 63 0.017
compound eye morphogenesis GO:0001745 249 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
purine nucleoside catabolic process GO:0006152 112 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
cellular catabolic process GO:0044248 372 0.016
axonogenesis GO:0007409 290 0.016
regulation of immune system process GO:0002682 176 0.016
Human
ribonucleoside triphosphate catabolic process GO:0009203 108 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
molting cycle chitin based cuticle GO:0007591 56 0.016
connective tissue development GO:0061448 3 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
regulation of response to stress GO:0080134 200 0.015
Human
nucleoside phosphate catabolic process GO:1901292 110 0.015
kidney development GO:0001822 3 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
sensory organ morphogenesis GO:0090596 260 0.015
cellular ketone metabolic process GO:0042180 24 0.015
organelle fission GO:0048285 340 0.015
learning or memory GO:0007611 141 0.015
protein localization GO:0008104 284 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
tube development GO:0035295 244 0.015
response to lipopolysaccharide GO:0032496 4 0.015
positive regulation of hydrolase activity GO:0051345 78 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
Human
dorsal ventral pattern formation GO:0009953 133 0.015
appendage development GO:0048736 401 0.015
response to organophosphorus GO:0046683 2 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
regulation of localization GO:0032879 275 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
apoptotic process GO:0006915 159 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
cell death GO:0008219 279 0.014
nucleoside catabolic process GO:0009164 112 0.014
regulation of transport GO:0051049 181 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
single organism intracellular transport GO:1902582 207 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
single organism biosynthetic process GO:0044711 206 0.014
cellular protein modification process GO:0006464 438 0.014
open tracheal system development GO:0007424 204 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
regulation of anatomical structure size GO:0090066 163 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
aromatic compound catabolic process GO:0019439 166 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
Human
regulation of cell morphogenesis GO:0022604 163 0.014
chemotaxis GO:0006935 249 0.014
nucleoside metabolic process GO:0009116 127 0.014
forebrain development GO:0030900 2 0.014
immune response activating signal transduction GO:0002757 2 0.013
Human
response to light stimulus GO:0009416 124 0.013
camera type eye morphogenesis GO:0048593 2 0.013
regulation of cell cycle GO:0051726 291 0.013
locomotory behavior GO:0007626 176 0.013
positive regulation of cell migration GO:0030335 2 0.013
heart process GO:0003015 37 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
multicellular organismal aging GO:0010259 140 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
flight behavior GO:0007629 26 0.013
regulation of growth GO:0040008 233 0.013
cell division GO:0051301 248 0.013
cell adhesion GO:0007155 136 0.013
retina development in camera type eye GO:0060041 4 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
kidney epithelium development GO:0072073 3 0.013
nephron epithelium development GO:0072009 3 0.013
nuclear division GO:0000280 332 0.013
cellular response to radiation GO:0071478 52 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
regulation of developmental growth GO:0048638 174 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
transmembrane transport GO:0055085 139 0.013
nucleotide catabolic process GO:0009166 109 0.013
oxidation reduction process GO:0055114 123 0.013
ion transmembrane transport GO:0034220 122 0.013
regulation of proteolysis GO:0030162 87 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
memory GO:0007613 94 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
Human
localization of cell GO:0051674 257 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
appendage morphogenesis GO:0035107 397 0.012
single organism membrane organization GO:0044802 93 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
cellular response to light stimulus GO:0071482 37 0.012
response to monosaccharide GO:0034284 4 0.012
salivary gland morphogenesis GO:0007435 145 0.012
adult locomotory behavior GO:0008344 76 0.012
intracellular transport GO:0046907 228 0.012
multicellular organismal reproductive behavior GO:0033057 110 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
organic hydroxy compound metabolic process GO:1901615 83 0.012
response to glucose GO:0009749 2 0.012
regulation of cell differentiation GO:0045595 302 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
positive regulation of nucleotide metabolic process GO:0045981 55 0.012
gtp metabolic process GO:0046039 72 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
macromolecular complex assembly GO:0065003 256 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
negative regulation of developmental process GO:0051093 201 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
nucleotide biosynthetic process GO:0009165 34 0.011
regulation of synaptic transmission GO:0050804 69 0.011
exocrine system development GO:0035272 162 0.011
phototransduction GO:0007602 52 0.011
circulatory system process GO:0003013 37 0.011
dendrite development GO:0016358 204 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
regulation of programmed cell death GO:0043067 152 0.011
actin filament organization GO:0007015 126 0.011
mating behavior GO:0007617 106 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
mitotic nuclear division GO:0007067 213 0.011
homeostatic process GO:0042592 199 0.011
wing disc morphogenesis GO:0007472 344 0.011
ribose phosphate biosynthetic process GO:0046390 28 0.011
programmed cell death GO:0012501 257 0.011
detection of stimulus involved in sensory perception GO:0050906 92 0.011
developmental growth GO:0048589 280 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
Human
regulation of ras protein signal transduction GO:0046578 93 0.011
cell cycle phase transition GO:0044770 140 0.011
gland development GO:0048732 191 0.011
larval locomotory behavior GO:0008345 27 0.011
developmental maturation GO:0021700 172 0.011
gtp catabolic process GO:0006184 72 0.011
response to biotic stimulus GO:0009607 294 0.010
Human
cellular response to carbohydrate stimulus GO:0071322 4 0.010
protein transport GO:0015031 155 0.010
mesenchymal cell development GO:0014031 1 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
regulation of hydrolase activity GO:0051336 97 0.010
regulation of neurotransmitter levels GO:0001505 38 0.010
neuron projection guidance GO:0097485 241 0.010
transcription from rna polymerase ii promoter GO:0006366 368 0.010
protein complex assembly GO:0006461 200 0.010
tissue death GO:0016271 102 0.010
regulation of cellular catabolic process GO:0031329 157 0.010
cytoplasmic transport GO:0016482 130 0.010
stem cell division GO:0017145 69 0.010
muscle system process GO:0003012 21 0.010
metal ion transport GO:0030001 74 0.010
regulation of nervous system development GO:0051960 248 0.010
cell maturation GO:0048469 144 0.010
cellular protein localization GO:0034613 160 0.010
imaginal disc derived wing morphogenesis GO:0007476 337 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.010
response to nutrient levels GO:0031667 114 0.010
gland morphogenesis GO:0022612 145 0.010
monocarboxylic acid transport GO:0015718 3 0.010
mapk cascade GO:0000165 107 0.010

TM4SF disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.016
sensory system disease DOID:0050155 0 0.012
musculoskeletal system disease DOID:17 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010
diabetes mellitus DOID:9351 0 0.010
type 2 diabetes mellitus DOID:9352 0 0.010
carbohydrate metabolism disease DOID:0050013 0 0.010
glucose metabolism disease DOID:4194 0 0.010
acquired metabolic disease DOID:0060158 0 0.010