Drosophila melanogaster

0 known processes

Ama (Dmel_CG2198)

Amalgam

(Aliases: M109,AMA,Dmel\CG2198,CG2198,CT7244,BG:DS00276.6,ama)

Ama biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.189
post embryonic appendage morphogenesis GO:0035120 385 0.179
imaginal disc derived wing morphogenesis GO:0007476 337 0.173
compound eye morphogenesis GO:0001745 249 0.155
imaginal disc derived appendage development GO:0048737 399 0.153
catabolic process GO:0009056 409 0.134
proteolysis GO:0006508 192 0.131
wing disc morphogenesis GO:0007472 344 0.130
cuticle development GO:0042335 86 0.129
organonitrogen compound metabolic process GO:1901564 318 0.123
compound eye development GO:0048749 307 0.108
sensory organ morphogenesis GO:0090596 260 0.105
eye development GO:0001654 323 0.101
appendage morphogenesis GO:0035107 397 0.098
appendage development GO:0048736 401 0.091
eye morphogenesis GO:0048592 260 0.090
positive regulation of nucleic acid templated transcription GO:1903508 266 0.089
defense response to bacterium GO:0042742 178 0.088
oxoacid metabolic process GO:0043436 103 0.086
imaginal disc derived appendage morphogenesis GO:0035114 395 0.079
cellular catabolic process GO:0044248 372 0.079
positive regulation of gene expression GO:0010628 290 0.078
eye photoreceptor cell differentiation GO:0001754 145 0.078
organic acid metabolic process GO:0006082 103 0.077
organic substance catabolic process GO:1901575 308 0.075
establishment of localization in cell GO:0051649 402 0.074
homeostatic process GO:0042592 199 0.071
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.069
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.069
cell motility GO:0048870 251 0.068
epithelial cell differentiation GO:0030855 322 0.067
spindle organization GO:0007051 253 0.066
carboxylic acid metabolic process GO:0019752 92 0.065
ovarian follicle cell development GO:0030707 248 0.065
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.064
dna metabolic process GO:0006259 227 0.060
vesicle mediated transport GO:0016192 381 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.052
positive regulation of rna metabolic process GO:0051254 271 0.048
actin filament based process GO:0030029 220 0.048
positive regulation of biosynthetic process GO:0009891 316 0.047
forebrain development GO:0030900 2 0.047
response to nutrient levels GO:0031667 114 0.047
exocrine system development GO:0035272 162 0.046
regulation of catalytic activity GO:0050790 185 0.046
telencephalon development GO:0021537 2 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.044
macromolecular complex assembly GO:0065003 256 0.044
cell proliferation GO:0008283 299 0.044
regulation of molecular function GO:0065009 217 0.043
establishment of planar polarity GO:0001736 87 0.043
positive regulation of transcription dna templated GO:0045893 266 0.043
humoral immune response GO:0006959 117 0.043
dendrite development GO:0016358 204 0.043
brain development GO:0007420 120 0.041
body morphogenesis GO:0010171 2 0.040
epithelial cell development GO:0002064 274 0.040
response to organic substance GO:0010033 284 0.040
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.040
camera type eye development GO:0043010 4 0.040
cell migration GO:0016477 238 0.039
positive regulation of cellular biosynthetic process GO:0031328 316 0.038
immune response GO:0006955 246 0.038
photoreceptor cell differentiation GO:0046530 170 0.037
columnar cuboidal epithelial cell development GO:0002066 249 0.037
mitotic spindle organization GO:0007052 220 0.036
compound eye photoreceptor cell differentiation GO:0001751 140 0.036
regulation of cell morphogenesis GO:0022604 163 0.035
apoptotic process GO:0006915 159 0.035
intracellular signal transduction GO:0035556 300 0.035
carbohydrate derivative metabolic process GO:1901135 217 0.035
defense response to other organism GO:0098542 225 0.034
photoreceptor cell development GO:0042461 96 0.034
cell death GO:0008219 279 0.034
positive regulation of response to stimulus GO:0048584 323 0.034
gland morphogenesis GO:0022612 145 0.034
localization of cell GO:0051674 257 0.034
morphogenesis of a polarized epithelium GO:0001738 93 0.034
axonogenesis GO:0007409 290 0.033
malpighian tubule development GO:0072002 64 0.033
response to external biotic stimulus GO:0043207 293 0.033
positive regulation of rna biosynthetic process GO:1902680 266 0.033
salivary gland development GO:0007431 162 0.033
endocytosis GO:0006897 310 0.033
phagocytosis GO:0006909 215 0.033
cell fate specification GO:0001708 71 0.033
tissue morphogenesis GO:0048729 297 0.032
Fly
negative regulation of cell cycle process GO:0010948 109 0.032
cellular amino acid metabolic process GO:0006520 61 0.032
single organism catabolic process GO:0044712 228 0.031
response to other organism GO:0051707 293 0.031
protein phosphorylation GO:0006468 169 0.031
actin cytoskeleton organization GO:0030036 206 0.030
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.030
cellular protein modification process GO:0006464 438 0.030
regulation of phosphorus metabolic process GO:0051174 210 0.030
striated muscle cell development GO:0055002 50 0.030
cytoplasmic transport GO:0016482 130 0.030
regulation of anatomical structure morphogenesis GO:0022603 242 0.029
regulation of multicellular organismal development GO:2000026 414 0.029
regulation of cellular component biogenesis GO:0044087 201 0.029
programmed cell death GO:0012501 257 0.029
ameboidal type cell migration GO:0001667 151 0.029
notch signaling pathway GO:0007219 120 0.029
rna processing GO:0006396 147 0.029
positive regulation of signaling GO:0023056 243 0.029
negative regulation of response to stimulus GO:0048585 258 0.029
response to biotic stimulus GO:0009607 294 0.028
regulation of cell cycle GO:0051726 291 0.028
organophosphate metabolic process GO:0019637 195 0.028
dendrite morphogenesis GO:0048813 199 0.027
regulation of nervous system development GO:0051960 248 0.027
cellular component assembly involved in morphogenesis GO:0010927 151 0.027
negative regulation of signaling GO:0023057 219 0.027
organelle assembly GO:0070925 198 0.027
death GO:0016265 284 0.027
gland development GO:0048732 191 0.027
regulation of programmed cell death GO:0043067 152 0.027
response to oxygen containing compound GO:1901700 200 0.026
nuclear transport GO:0051169 72 0.026
aromatic compound catabolic process GO:0019439 166 0.026
regionalization GO:0003002 416 0.026
head development GO:0060322 135 0.026
organic substance transport GO:0071702 257 0.026
regulation of cell cycle process GO:0010564 181 0.026
salivary gland morphogenesis GO:0007435 145 0.026
digestive system development GO:0055123 149 0.026
neuron projection guidance GO:0097485 241 0.025
protein transport GO:0015031 155 0.025
regulation of organelle organization GO:0033043 196 0.025
morphogenesis of an epithelium GO:0002009 276 0.025
Fly
tissue migration GO:0090130 155 0.025
eggshell formation GO:0030703 105 0.024
cellular response to dna damage stimulus GO:0006974 223 0.024
anterior posterior pattern specification GO:0009952 136 0.024
regulation of apoptotic process GO:0042981 130 0.024
cell cycle checkpoint GO:0000075 95 0.024
chitin based cuticle development GO:0040003 49 0.024
muscle structure development GO:0061061 224 0.024
modification dependent protein catabolic process GO:0019941 78 0.023
salivary gland histolysis GO:0035070 88 0.023
wound healing GO:0042060 75 0.023
regulation of cell cycle phase transition GO:1901987 130 0.023
phosphorylation GO:0016310 294 0.023
regulation of cellular protein metabolic process GO:0032268 243 0.023
regulation of cell proliferation GO:0042127 163 0.023
hindbrain development GO:0030902 2 0.022
cellular protein catabolic process GO:0044257 83 0.022
positive regulation of hydrolase activity GO:0051345 78 0.022
positive regulation of molecular function GO:0044093 136 0.022
hindgut morphogenesis GO:0007442 58 0.022
regulation of notch signaling pathway GO:0008593 100 0.022
defense response GO:0006952 300 0.022
embryonic morphogenesis GO:0048598 206 0.022
Fly
regulation of mrna metabolic process GO:1903311 72 0.022
nucleoside phosphate metabolic process GO:0006753 162 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
anatomical structure homeostasis GO:0060249 97 0.021
Fly
negative regulation of signal transduction GO:0009968 206 0.021
tube morphogenesis GO:0035239 191 0.021
mrna splicing via spliceosome GO:0000398 73 0.021
digestive tract morphogenesis GO:0048546 127 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.021
positive regulation of signal transduction GO:0009967 223 0.021
nucleocytoplasmic transport GO:0006913 72 0.021
regulation of cell death GO:0010941 173 0.021
regulation of epithelial cell proliferation GO:0050678 4 0.020
regulation of mitotic cell cycle phase transition GO:1901990 130 0.020
positive regulation of cell communication GO:0010647 250 0.020
regulation of cell fate specification GO:0042659 27 0.020
establishment of tissue polarity GO:0007164 87 0.020
tube development GO:0035295 244 0.020
neuron recognition GO:0008038 101 0.020
regulation of response to stress GO:0080134 200 0.020
response to abiotic stimulus GO:0009628 341 0.020
regulation of gene silencing GO:0060968 63 0.020
protein modification process GO:0036211 438 0.020
mrna processing GO:0006397 104 0.019
organelle fission GO:0048285 340 0.019
carbohydrate derivative catabolic process GO:1901136 118 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
retina development in camera type eye GO:0060041 4 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
response to extracellular stimulus GO:0009991 116 0.019
intracellular transport GO:0046907 228 0.019
chemotaxis GO:0006935 249 0.019
mitotic cell cycle checkpoint GO:0007093 88 0.019
central nervous system development GO:0007417 201 0.019
stem cell differentiation GO:0048863 117 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.018
single organism biosynthetic process GO:0044711 206 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
mesenchymal cell development GO:0014031 1 0.018
response to endogenous stimulus GO:0009719 119 0.018
eye photoreceptor cell development GO:0042462 81 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
morphogenesis of embryonic epithelium GO:0016331 94 0.018
Fly
activation of cysteine type endopeptidase activity GO:0097202 17 0.018
mitotic dna integrity checkpoint GO:0044774 75 0.018
compound eye photoreceptor fate commitment GO:0001752 36 0.017
antimicrobial humoral response GO:0019730 99 0.017
cellular protein localization GO:0034613 160 0.017
chemical homeostasis GO:0048878 92 0.017
protein localization GO:0008104 284 0.017
regulation of catabolic process GO:0009894 170 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
epithelial cell migration GO:0010631 148 0.017
hindgut development GO:0061525 58 0.017
regulation of meiosis GO:0040020 3 0.017
negative regulation of cell cycle phase transition GO:1901988 103 0.017
camera type eye morphogenesis GO:0048593 2 0.017
cilium assembly GO:0042384 38 0.017
negative regulation of gene expression GO:0010629 387 0.017
developmental programmed cell death GO:0010623 138 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
mrna metabolic process GO:0016071 124 0.017
histolysis GO:0007559 102 0.016
protein processing GO:0016485 68 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
single organism intracellular transport GO:1902582 207 0.016
compound eye photoreceptor development GO:0042051 78 0.016
mitotic cell cycle phase transition GO:0044772 138 0.016
dna damage checkpoint GO:0000077 78 0.016
axon guidance GO:0007411 233 0.016
regulation of cell development GO:0060284 215 0.016
regulation of cell differentiation GO:0045595 302 0.016
response to lipopolysaccharide GO:0032496 4 0.016
response to lipid GO:0033993 38 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
regulation of proteolysis GO:0030162 87 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
glutamine metabolic process GO:0006541 4 0.016
embryonic pattern specification GO:0009880 174 0.016
cellular lipid metabolic process GO:0044255 83 0.016
protein catabolic process GO:0030163 101 0.015
amine metabolic process GO:0009308 12 0.015
negative regulation of cell communication GO:0010648 223 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
positive regulation of cell death GO:0010942 69 0.015
ras protein signal transduction GO:0007265 88 0.015
mitotic dna damage checkpoint GO:0044773 74 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.015
malpighian tubule morphogenesis GO:0007443 44 0.015
locomotory behavior GO:0007626 176 0.015
regulation of hydrolase activity GO:0051336 97 0.015
mitotic cytokinesis GO:0000281 50 0.015
regulation of chromatin silencing GO:0031935 36 0.015
regulation of mrna processing GO:0050684 71 0.015
response to starvation GO:0042594 97 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
protein complex biogenesis GO:0070271 201 0.015
photoreceptor cell fate commitment GO:0046552 41 0.015
negative regulation of cell cycle GO:0045786 116 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
heterocycle catabolic process GO:0046700 166 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
dna integrity checkpoint GO:0031570 81 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
immune system process GO:0002376 347 0.015
cellular amine metabolic process GO:0044106 12 0.014
respiratory system development GO:0060541 213 0.014
Fly
positive regulation of protein metabolic process GO:0051247 128 0.014
renal tubule development GO:0061326 64 0.014
lipid metabolic process GO:0006629 121 0.014
macromolecule catabolic process GO:0009057 161 0.014
digestive tract development GO:0048565 149 0.014
chemosensory behavior GO:0007635 106 0.014
kidney development GO:0001822 3 0.014
regulation of mitosis GO:0007088 56 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
open tracheal system development GO:0007424 204 0.014
Fly
positive regulation of cellular component organization GO:0051130 156 0.014
growth GO:0040007 359 0.014
chromatin assembly or disassembly GO:0006333 52 0.014
synaptic transmission GO:0007268 288 0.014
regulation of protein metabolic process GO:0051246 256 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
response to organic cyclic compound GO:0014070 89 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
determination of adult lifespan GO:0008340 137 0.014
cellular macromolecule localization GO:0070727 220 0.014
regulation of organ morphogenesis GO:2000027 78 0.014
neuron fate commitment GO:0048663 50 0.013
synapse organization GO:0050808 196 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
regulation of phosphorylation GO:0042325 147 0.013
ion transport GO:0006811 145 0.013
rna splicing via transesterification reactions GO:0000375 73 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
regulation of cell shape GO:0008360 113 0.013
sulfur compound metabolic process GO:0006790 59 0.013
gtp metabolic process GO:0046039 72 0.013
regulation of transferase activity GO:0051338 58 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of humoral immune response GO:0002920 51 0.013
mitotic g2 m transition checkpoint GO:0044818 70 0.013
larval behavior GO:0030537 42 0.013
establishment of organelle localization GO:0051656 122 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.013
connective tissue development GO:0061448 3 0.013
proteasomal protein catabolic process GO:0010498 59 0.013
eye photoreceptor cell fate commitment GO:0042706 37 0.013
tissue death GO:0016271 102 0.013
nuclear division GO:0000280 332 0.013
stem cell development GO:0048864 79 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.012
segmentation GO:0035282 207 0.012
apoptotic process involved in development GO:1902742 20 0.012
spermatogenesis GO:0007283 200 0.012
negative regulation of immune system process GO:0002683 50 0.012
axon development GO:0061564 297 0.012
response to wounding GO:0009611 94 0.012
regulation of localization GO:0032879 275 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
striated muscle cell differentiation GO:0051146 90 0.012
establishment of protein localization GO:0045184 163 0.012
sperm motility GO:0030317 12 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
regulation of protein catabolic process GO:0042176 55 0.012
muscle cell development GO:0055001 50 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
cell cycle phase transition GO:0044770 140 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
intracellular protein transport GO:0006886 104 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
endomembrane system organization GO:0010256 119 0.012
protein complex assembly GO:0006461 200 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
imaginal disc pattern formation GO:0007447 91 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
response to monosaccharide GO:0034284 4 0.011
positive regulation of apoptotic signaling pathway GO:2001235 4 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
mitotic nuclear division GO:0007067 213 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
peptide metabolic process GO:0006518 80 0.011
multicellular organismal aging GO:0010259 140 0.011
regulation of embryonic development GO:0045995 68 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
establishment of ommatidial planar polarity GO:0042067 49 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
synapse assembly GO:0007416 143 0.011
negative regulation of cell development GO:0010721 62 0.011
somatic muscle development GO:0007525 66 0.011
cellularization GO:0007349 90 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
renal tubule morphogenesis GO:0061333 44 0.011
cell division GO:0051301 248 0.011
retina morphogenesis in camera type eye GO:0060042 2 0.011
wing disc pattern formation GO:0035222 66 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
rna splicing GO:0008380 83 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.011
neural retina development GO:0003407 4 0.011
cellular response to organic substance GO:0071310 132 0.010
defense response to gram negative bacterium GO:0050829 94 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
cell recognition GO:0008037 102 0.010
r7 cell differentiation GO:0045466 43 0.010
sterol homeostasis GO:0055092 4 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010
regulation of nuclear division GO:0051783 58 0.010
organophosphate catabolic process GO:0046434 112 0.010
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.010
skeletal muscle fiber development GO:0048741 3 0.010
renal system development GO:0072001 72 0.010
nephron epithelium morphogenesis GO:0072088 3 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
response to hexose GO:0009746 3 0.010
negative regulation of nervous system development GO:0051961 92 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
nephron development GO:0072006 3 0.010

Ama disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.013
cardiovascular system disease DOID:1287 0 0.011