Drosophila melanogaster

16 known processes

Hsp22 (Dmel_CG4460)

Heat shock protein 22

(Aliases: CG4460,EP(3)3247,22,Dmel\CG4460,anon-WO0140519.138,hsp22,DmHsp22,CG32041,small hsp locus 67B,anon-WO0118547.50)

Hsp22 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception GO:0007600 196 0.914
Human
multicellular organismal aging GO:0010259 140 0.749
response to cold GO:0009409 13 0.699
Fly
determination of adult lifespan GO:0008340 137 0.676
defense response to other organism GO:0098542 225 0.475
Fly
response to abiotic stimulus GO:0009628 341 0.364
aging GO:0007568 143 0.343
response to oxidative stress GO:0006979 86 0.326
response to hydrogen peroxide GO:0042542 11 0.319
Rat
regulation of growth GO:0040008 233 0.276
Rat
response to oxygen containing compound GO:1901700 200 0.257
Rat
response to bacterium GO:0009617 198 0.227
Fly
response to temperature stimulus GO:0009266 106 0.192
response to other organism GO:0051707 293 0.134
Fly
detection of stimulus GO:0051606 156 0.130
reactive oxygen species metabolic process GO:0072593 22 0.129
Rat
microtubule organizing center organization GO:0031023 168 0.126
response to organic substance GO:0010033 284 0.124
Rat
establishment of localization in cell GO:0051649 402 0.122
Human
negative regulation of reactive oxygen species metabolic process GO:2000378 1 0.121
Rat
response to alcohol GO:0097305 95 0.117
Rat
regulation of cell death GO:0010941 173 0.111
Human Rat
centrosome organization GO:0051297 163 0.109
cellular response to oxidative stress GO:0034599 28 0.107
intracellular signal transduction GO:0035556 300 0.103
Rat
negative regulation of cellular response to oxidative stress GO:1900408 1 0.098
tissue migration GO:0090130 155 0.097
defense response GO:0006952 300 0.094
Fly
response to heat GO:0009408 63 0.090
response to reactive oxygen species GO:0000302 24 0.090
Rat
camera type eye development GO:0043010 4 0.090
epithelial cell migration GO:0010631 148 0.087
posttranscriptional regulation of gene expression GO:0010608 145 0.082
response to biotic stimulus GO:0009607 294 0.081
Fly
regulation of reactive oxygen species metabolic process GO:2000377 8 0.076
Rat
regulation of multi organism process GO:0043900 131 0.066
regulation of cell growth GO:0001558 43 0.066
Rat
negative regulation of response to oxidative stress GO:1902883 1 0.065
visual perception GO:0007601 9 0.065
Human
ovarian follicle cell migration GO:0007297 121 0.064
regulation of response to oxidative stress GO:1902882 4 0.062
cell death GO:0008219 279 0.060
Human Rat
mapk cascade GO:0000165 107 0.060
Rat
detection of abiotic stimulus GO:0009582 66 0.059
protein maturation GO:0051604 71 0.058
response to ionizing radiation GO:0010212 32 0.058
Human
response to endogenous stimulus GO:0009719 119 0.058
Rat
intracellular transport GO:0046907 228 0.056
Human
behavioral response to starvation GO:0042595 6 0.056
Fly
apoptotic process involved in morphogenesis GO:0060561 3 0.055
epithelium migration GO:0090132 148 0.055
response to external biotic stimulus GO:0043207 293 0.054
Fly
regulation of cellular response to oxidative stress GO:1900407 4 0.054
regulation of intracellular transport GO:0032386 64 0.053
Human
regulation of apoptotic process GO:0042981 130 0.052
Human Rat
signal transduction by phosphorylation GO:0023014 107 0.051
Rat
negative regulation of cellular metabolic process GO:0031324 382 0.051
Rat
apoptotic process GO:0006915 159 0.050
Human Rat
neurological system process GO:0050877 358 0.050
Human
response to hypoxia GO:0001666 53 0.049
Fly
programmed cell death GO:0012501 257 0.049
Human Rat
detection of external stimulus GO:0009581 66 0.048
regulation of intracellular signal transduction GO:1902531 236 0.048
growth GO:0040007 359 0.048
Rat
response to decreased oxygen levels GO:0036293 58 0.047
Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.047
organic substance catabolic process GO:1901575 308 0.046
macromolecular complex assembly GO:0065003 256 0.045
Human
heat shock mediated polytene chromosome puffing GO:0035080 7 0.044
positive regulation of protein metabolic process GO:0051247 128 0.044
response to nutrient levels GO:0031667 114 0.042
Fly
developmental programmed cell death GO:0010623 138 0.042
regulation of transport GO:0051049 181 0.042
Human
stress activated mapk cascade GO:0051403 52 0.041
Rat
defense response to bacterium GO:0042742 178 0.041
Fly
regulation of cellular catabolic process GO:0031329 157 0.040
transmembrane transport GO:0055085 139 0.040
detection of stimulus involved in sensory perception GO:0050906 92 0.039
regulation of response to stress GO:0080134 200 0.039
regulation of protein metabolic process GO:0051246 256 0.039
regulation of localization GO:0032879 275 0.039
Human
ameboidal type cell migration GO:0001667 151 0.039
centrosome cycle GO:0007098 137 0.038
negative regulation of intracellular signal transduction GO:1902532 57 0.038
organonitrogen compound biosynthetic process GO:1901566 117 0.037
proteolysis GO:0006508 192 0.037
chromosome organization GO:0051276 360 0.036
appendage development GO:0048736 401 0.035
Fly
defense response to fungus GO:0050832 48 0.035
Fly
apoptotic signaling pathway GO:0097190 27 0.033
microtubule polymerization or depolymerization GO:0031109 39 0.033
Rat
apoptotic process involved in development GO:1902742 20 0.032
stress activated protein kinase signaling cascade GO:0031098 55 0.031
Rat
organonitrogen compound metabolic process GO:1901564 318 0.031
rhythmic behavior GO:0007622 76 0.030
response to oxygen levels GO:0070482 59 0.030
Fly
appendage morphogenesis GO:0035107 397 0.029
Fly
negative regulation of response to stimulus GO:0048585 258 0.029
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
regulation of catabolic process GO:0009894 170 0.029
translation GO:0006412 69 0.028
camera type eye morphogenesis GO:0048593 2 0.028
muscle organ development GO:0007517 127 0.028
cellular macromolecular complex assembly GO:0034622 153 0.028
rhythmic process GO:0048511 106 0.028
epithelial cell differentiation GO:0030855 322 0.028
protein processing GO:0016485 68 0.027
positive regulation of immune system process GO:0002684 68 0.027
wing disc morphogenesis GO:0007472 344 0.026
Fly
intrinsic apoptotic signaling pathway GO:0097193 16 0.026
response to virus GO:0009615 28 0.026
response to nitrogen compound GO:1901698 90 0.026
response to extracellular stimulus GO:0009991 116 0.026
Fly
establishment of protein localization GO:0045184 163 0.026
embryonic morphogenesis GO:0048598 206 0.026
negative regulation of signaling GO:0023057 219 0.025
regulation of translation GO:0006417 56 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
purine containing compound metabolic process GO:0072521 155 0.024
peptide metabolic process GO:0006518 80 0.024
negative regulation of cellular protein metabolic process GO:0032269 85 0.024
regulation of phosphate metabolic process GO:0019220 210 0.024
cellular protein modification process GO:0006464 438 0.024
cellular response to dna damage stimulus GO:0006974 223 0.024
response to organonitrogen compound GO:0010243 75 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
muscle structure development GO:0061061 224 0.023
negative regulation of gene expression GO:0010629 387 0.023
protein transport GO:0015031 155 0.023
inorganic cation transmembrane transport GO:0098662 61 0.023
positive regulation of cell motility GO:2000147 3 0.023
negative regulation of protein metabolic process GO:0051248 85 0.022
nitrogen compound transport GO:0071705 85 0.022
negative regulation of programmed cell death GO:0043069 72 0.022
Human Rat
cellular modified amino acid metabolic process GO:0006575 45 0.022
positive regulation of cell communication GO:0010647 250 0.022
organic substance transport GO:0071702 257 0.022
cellular response to ionizing radiation GO:0071479 15 0.022
Human
response to organic cyclic compound GO:0014070 89 0.022
Rat
regulation of protein processing GO:0070613 32 0.022
epithelial cell development GO:0002064 274 0.022
phagocytosis GO:0006909 215 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
organelle fission GO:0048285 340 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
embryonic pattern specification GO:0009880 174 0.021
cellular response to chemical stimulus GO:0070887 199 0.020
protein complex biogenesis GO:0070271 201 0.020
Human
negative regulation of cell communication GO:0010648 223 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
Fly
small molecule metabolic process GO:0044281 305 0.019
catabolic process GO:0009056 409 0.019
rna localization GO:0006403 115 0.019
positive regulation of immune response GO:0050778 63 0.019
negative regulation of cell death GO:0060548 81 0.019
Human Rat
positive regulation of cell migration GO:0030335 2 0.019
regulation of proteolysis GO:0030162 87 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
centrosome duplication GO:0051298 121 0.018
negative regulation of growth GO:0045926 84 0.017
Rat
response to radiation GO:0009314 155 0.017
Human
cellular catabolic process GO:0044248 372 0.017
cellular response to heat GO:0034605 24 0.017
death GO:0016265 284 0.017
Human Rat
purine nucleotide metabolic process GO:0006163 146 0.017
membrane organization GO:0061024 112 0.017
protein dna complex assembly GO:0065004 63 0.016
single organism behavior GO:0044708 391 0.016
regulation of catalytic activity GO:0050790 185 0.016
blastoderm segmentation GO:0007350 159 0.016
regulation of cellular response to stress GO:0080135 89 0.016
eye development GO:0001654 323 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
Fly
positive regulation of signaling GO:0023056 243 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
cell motility GO:0048870 251 0.015
positive regulation of growth GO:0045927 75 0.015
regulation of behavior GO:0050795 75 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
jak stat cascade GO:0007259 49 0.015
response to inorganic substance GO:0010035 44 0.015
Rat
eye morphogenesis GO:0048592 260 0.015
cellular amide metabolic process GO:0043603 80 0.015
regulation of molecular function GO:0065009 217 0.015
cell growth GO:0016049 108 0.015
Rat
oxoacid metabolic process GO:0043436 103 0.015
negative regulation of signal transduction GO:0009968 206 0.015
response to starvation GO:0042594 97 0.014
Fly
regulation of immune response GO:0050776 118 0.014
forebrain development GO:0030900 2 0.014
body morphogenesis GO:0010171 2 0.014
autophagy GO:0006914 108 0.014
rna splicing GO:0008380 83 0.014
response to fungus GO:0009620 50 0.014
Fly
defense response to gram negative bacterium GO:0050829 94 0.014
nucleotide metabolic process GO:0009117 161 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
regulation of kinase activity GO:0043549 53 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
mitotic nuclear division GO:0007067 213 0.013
homeostatic process GO:0042592 199 0.013
regulation of peptidase activity GO:0052547 39 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
amide biosynthetic process GO:0043604 42 0.013
intracellular protein transport GO:0006886 104 0.013
localization of cell GO:0051674 257 0.013
polytene chromosome puffing GO:0035079 7 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
protein dna complex subunit organization GO:0071824 86 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
cellular response to organic substance GO:0071310 132 0.013
macromolecule catabolic process GO:0009057 161 0.013
energy derivation by oxidation of organic compounds GO:0015980 32 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
glycosyl compound metabolic process GO:1901657 127 0.012
kidney development GO:0001822 3 0.012
spindle organization GO:0007051 253 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
regulation of insulin receptor signaling pathway GO:0046626 17 0.012
response to hormone GO:0009725 45 0.012
Rat
dna conformation change GO:0071103 105 0.012
positive regulation of apoptotic signaling pathway GO:2001235 4 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
protein localization GO:0008104 284 0.012
single organism intracellular transport GO:1902582 207 0.012
organophosphate metabolic process GO:0019637 195 0.012
protein modification process GO:0036211 438 0.012
response to gamma radiation GO:0010332 17 0.012
Human
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
endocytosis GO:0006897 310 0.012
cell adhesion GO:0007155 136 0.011
cell cycle phase transition GO:0044770 140 0.011
cellular response to gamma radiation GO:0071480 10 0.011
Human
oxidation reduction process GO:0055114 123 0.011
response to monosaccharide GO:0034284 4 0.011
regulation of phosphorylation GO:0042325 147 0.011
cellular response to abiotic stimulus GO:0071214 58 0.011
Human
negative regulation of protein processing GO:0010955 31 0.011
immune response activating signal transduction GO:0002757 2 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
response to lipopolysaccharide GO:0032496 4 0.011
glutathione metabolic process GO:0006749 37 0.011
nuclear division GO:0000280 332 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
protein complex assembly GO:0006461 200 0.011
Human
regulation of ras protein signal transduction GO:0046578 93 0.011
regulation of developmental growth GO:0048638 174 0.011
protein phosphorylation GO:0006468 169 0.011
jnk cascade GO:0007254 50 0.011
heterocycle catabolic process GO:0046700 166 0.010
negative regulation of cell cycle GO:0045786 116 0.010
positive regulation of macromolecule metabolic process GO:0010604 405 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010
Fly
inorganic ion transmembrane transport GO:0098660 73 0.010
open tracheal system development GO:0007424 204 0.010
nucleoside metabolic process GO:0009116 127 0.010
regulation of protein localization GO:0032880 76 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
antimicrobial humoral response GO:0019730 99 0.010

Hsp22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
motor neuron disease DOID:231 0 0.056
Human
central nervous system disease DOID:331 0 0.056
Human
disease of anatomical entity DOID:7 0 0.056
Human
neurodegenerative disease DOID:1289 0 0.056
Human
nervous system disease DOID:863 0 0.056
Human
cardiovascular system disease DOID:1287 0 0.021
Human
musculoskeletal system disease DOID:17 0 0.020
Human
sensory system disease DOID:0050155 0 0.017
Human
eye and adnexa disease DOID:1492 0 0.017
Human
eye disease DOID:5614 0 0.015
Human
neuropathy DOID:870 0 0.014
Human
neuromuscular disease DOID:440 0 0.011
Human
muscular disease DOID:0080000 0 0.010
Human