Drosophila melanogaster

29 known processes

RhoGAP54D (Dmel_CG6477)

CG6477 gene product from transcript CG6477-RA

(Aliases: CG6477,Dmel\CG6477)

RhoGAP54D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle fission GO:0048285 340 0.400
microtubule organizing center organization GO:0031023 168 0.244
negative regulation of cellular metabolic process GO:0031324 382 0.150
chromosome organization GO:0051276 360 0.146
intracellular signal transduction GO:0035556 300 0.145
establishment or maintenance of cell polarity GO:0007163 167 0.144
nuclear division GO:0000280 332 0.140
centrosome organization GO:0051297 163 0.134
female meiotic division GO:0007143 70 0.117
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.114
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.113
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.112
purine nucleoside triphosphate catabolic process GO:0009146 108 0.107
positive regulation of gene expression GO:0010628 290 0.106
spindle organization GO:0007051 253 0.105
positive regulation of nucleic acid templated transcription GO:1903508 266 0.101
mitotic nuclear division GO:0007067 213 0.096
organonitrogen compound metabolic process GO:1901564 318 0.091
nucleoside triphosphate metabolic process GO:0009141 120 0.085
protein modification process GO:0036211 438 0.083
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.083
meiotic cell cycle process GO:1903046 132 0.081
purine nucleoside catabolic process GO:0006152 112 0.081
nucleoside triphosphate catabolic process GO:0009143 108 0.080
regulation of phosphate metabolic process GO:0019220 210 0.080
mitotic cell cycle checkpoint GO:0007093 88 0.080
negative regulation of gene expression GO:0010629 387 0.078
nucleotide catabolic process GO:0009166 109 0.078
ras protein signal transduction GO:0007265 88 0.077
meiotic cell cycle GO:0051321 171 0.077
dna metabolic process GO:0006259 227 0.077
chromatin organization GO:0006325 207 0.076
transcription from rna polymerase ii promoter GO:0006366 368 0.076
cellular catabolic process GO:0044248 372 0.074
meiosis i GO:0007127 59 0.073
regulation of intracellular signal transduction GO:1902531 236 0.073
mitotic spindle organization GO:0007052 220 0.072
regulation of catabolic process GO:0009894 170 0.071
positive regulation of rna biosynthetic process GO:1902680 266 0.071
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.071
organic substance catabolic process GO:1901575 308 0.070
purine nucleoside metabolic process GO:0042278 127 0.068
positive regulation of macromolecule metabolic process GO:0010604 405 0.068
negative regulation of nucleic acid templated transcription GO:1903507 240 0.067
nucleotide metabolic process GO:0009117 161 0.067
small molecule metabolic process GO:0044281 305 0.066
glycosyl compound catabolic process GO:1901658 112 0.066
negative regulation of rna metabolic process GO:0051253 251 0.063
single organism catabolic process GO:0044712 228 0.060
carbohydrate derivative catabolic process GO:1901136 118 0.059
small gtpase mediated signal transduction GO:0007264 88 0.059
single organism behavior GO:0044708 391 0.058
negative regulation of response to stimulus GO:0048585 258 0.058
negative regulation of cellular biosynthetic process GO:0031327 277 0.055
ribonucleoside metabolic process GO:0009119 127 0.055
purine nucleotide catabolic process GO:0006195 109 0.055
nucleoside catabolic process GO:0009164 112 0.054
purine containing compound catabolic process GO:0072523 112 0.052
heterocycle catabolic process GO:0046700 166 0.052
spermatogenesis GO:0007283 200 0.052
purine nucleotide metabolic process GO:0006163 146 0.051
chromosome condensation GO:0030261 41 0.051
ribose phosphate metabolic process GO:0019693 145 0.050
ribonucleoside triphosphate metabolic process GO:0009199 119 0.050
mitotic g2 m transition checkpoint GO:0044818 70 0.049
regulation of cellular amino acid metabolic process GO:0006521 0 0.049
ribonucleotide catabolic process GO:0009261 109 0.048
purine nucleoside triphosphate metabolic process GO:0009144 119 0.047
purine containing compound metabolic process GO:0072521 155 0.047
ribonucleoside triphosphate catabolic process GO:0009203 108 0.047
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.047
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.047
organophosphate metabolic process GO:0019637 195 0.047
positive regulation of cellular biosynthetic process GO:0031328 316 0.047
chromosome segregation GO:0007059 157 0.046
sister chromatid segregation GO:0000819 92 0.046
meiotic nuclear division GO:0007126 151 0.046
carbohydrate derivative metabolic process GO:1901135 217 0.045
male meiosis chromosome segregation GO:0007060 10 0.045
positive regulation of phosphorus metabolic process GO:0010562 139 0.044
dna conformation change GO:0071103 105 0.044
cellular protein localization GO:0034613 160 0.042
g2 dna damage checkpoint GO:0031572 69 0.042
nucleoside metabolic process GO:0009116 127 0.042
organonitrogen compound catabolic process GO:1901565 128 0.041
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.041
cell division GO:0051301 248 0.041
positive regulation of biosynthetic process GO:0009891 316 0.040
nucleobase containing small molecule metabolic process GO:0055086 174 0.039
purine ribonucleotide catabolic process GO:0009154 109 0.039
protein localization GO:0008104 284 0.038
nucleoside phosphate metabolic process GO:0006753 162 0.038
glycosyl compound metabolic process GO:1901657 127 0.038
purine ribonucleotide metabolic process GO:0009150 145 0.038
mitotic cell cycle phase transition GO:0044772 138 0.037
histone modification GO:0016570 106 0.037
positive regulation of transcription dna templated GO:0045893 266 0.037
regulation of phosphorus metabolic process GO:0051174 210 0.037
positive regulation of gtpase activity GO:0043547 43 0.036
chromatin remodeling GO:0006338 72 0.036
body morphogenesis GO:0010171 2 0.036
mitotic chromosome condensation GO:0007076 22 0.036
negative regulation of biosynthetic process GO:0009890 277 0.036
organic cyclic compound catabolic process GO:1901361 168 0.036
negative regulation of cell cycle phase transition GO:1901988 103 0.035
nucleobase containing compound catabolic process GO:0034655 165 0.035
purine ribonucleoside metabolic process GO:0046128 127 0.034
organophosphate catabolic process GO:0046434 112 0.034
ribonucleotide metabolic process GO:0009259 145 0.033
proteolysis GO:0006508 192 0.033
dna packaging GO:0006323 91 0.033
male gamete generation GO:0048232 201 0.033
organic substance transport GO:0071702 257 0.033
regulation of phosphorylation GO:0042325 147 0.032
cellular protein modification process GO:0006464 438 0.031
negative regulation of transcription dna templated GO:0045892 237 0.031
cellular response to dna damage stimulus GO:0006974 223 0.031
regulation of localization GO:0032879 275 0.030
regulation of mitotic cell cycle GO:0007346 190 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
centrosome duplication GO:0051298 121 0.030
epithelial cell differentiation GO:0030855 322 0.030
cell proliferation GO:0008283 299 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.029
atp metabolic process GO:0046034 49 0.029
regulation of cellular protein metabolic process GO:0032268 243 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.029
mitotic dna integrity checkpoint GO:0044774 75 0.028
cellular macromolecule localization GO:0070727 220 0.028
regulation of mitosis GO:0007088 56 0.028
regulation of microtubule cytoskeleton organization GO:0070507 41 0.028
negative regulation of cell communication GO:0010648 223 0.027
positive regulation of cell communication GO:0010647 250 0.027
cellular nitrogen compound catabolic process GO:0044270 165 0.027
regulation of organelle organization GO:0033043 196 0.027
response to organic substance GO:0010033 284 0.027
sensory organ morphogenesis GO:0090596 260 0.026
phosphorylation GO:0016310 294 0.026
regionalization GO:0003002 416 0.026
regulation of mitotic cell cycle phase transition GO:1901990 130 0.026
negative regulation of mitotic cell cycle GO:0045930 109 0.025
positive regulation of cellular catabolic process GO:0031331 95 0.024
death GO:0016265 284 0.024
purine ribonucleoside catabolic process GO:0046130 112 0.024
positive regulation of signal transduction GO:0009967 223 0.024
regulation of protein metabolic process GO:0051246 256 0.024
eye morphogenesis GO:0048592 260 0.024
localization of cell GO:0051674 257 0.023
meiotic chromosome condensation GO:0010032 3 0.023
aromatic compound catabolic process GO:0019439 166 0.023
ribonucleoside catabolic process GO:0042454 112 0.023
organic acid metabolic process GO:0006082 103 0.023
regulation of cellular catabolic process GO:0031329 157 0.023
segmentation GO:0035282 207 0.023
positive regulation of signaling GO:0023056 243 0.022
signal transduction by phosphorylation GO:0023014 107 0.022
mitotic sister chromatid segregation GO:0000070 87 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.022
protein complex assembly GO:0006461 200 0.021
neuroblast division GO:0055057 35 0.021
regulation of cell cycle GO:0051726 291 0.021
maintenance of protein location in cell GO:0032507 26 0.021
response to radiation GO:0009314 155 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
regulation of small gtpase mediated signal transduction GO:0051056 93 0.021
regulation of cellular response to stress GO:0080135 89 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
positive regulation of nucleotide metabolic process GO:0045981 55 0.020
catabolic process GO:0009056 409 0.020
nuclear dna replication GO:0033260 1 0.020
ribonucleoside monophosphate catabolic process GO:0009158 39 0.020
spindle assembly GO:0051225 80 0.020
regulation of microtubule based process GO:0032886 49 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.019
regulation of mapk cascade GO:0043408 92 0.019
regulation of programmed cell death GO:0043067 152 0.019
behavioral response to pain GO:0048266 3 0.019
ubiquitin dependent protein catabolic process GO:0006511 78 0.019
guanosine containing compound metabolic process GO:1901068 74 0.019
regulation of cell death GO:0010941 173 0.019
single organism cellular localization GO:1902580 180 0.019
positive regulation of nucleotide catabolic process GO:0030813 46 0.019
negative regulation of cell cycle process GO:0010948 109 0.019
embryonic morphogenesis GO:0048598 206 0.019
mapk cascade GO:0000165 107 0.019
programmed cell death GO:0012501 257 0.019
regulation of molecular function GO:0065009 217 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
chromosome separation GO:0051304 42 0.018
ribonucleoside monophosphate metabolic process GO:0009161 51 0.018
spermatid differentiation GO:0048515 114 0.018
mitotic dna damage checkpoint GO:0044773 74 0.018
apoptotic process GO:0006915 159 0.017
axon guidance GO:0007411 233 0.017
centrosome cycle GO:0007098 137 0.017
regulation of cell cycle process GO:0010564 181 0.017
macromolecule catabolic process GO:0009057 161 0.017
regulation of cell development GO:0060284 215 0.017
regulation of response to stress GO:0080134 200 0.017
histone lysine demethylation GO:0070076 6 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
covalent chromatin modification GO:0016569 106 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.016
cellularization GO:0007349 90 0.016
cell death GO:0008219 279 0.016
negative regulation of cell death GO:0060548 81 0.016
establishment of cell polarity GO:0030010 40 0.016
cell motility GO:0048870 251 0.016
maintenance of location GO:0051235 73 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.016
response to pain GO:0048265 3 0.016
protein dna complex assembly GO:0065004 63 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
dna damage checkpoint GO:0000077 78 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
skin development GO:0043588 65 0.015
proteasomal protein catabolic process GO:0010498 59 0.015
response to external biotic stimulus GO:0043207 293 0.015
dna integrity checkpoint GO:0031570 81 0.015
regulation of chromosome organization GO:0033044 64 0.015
gtp metabolic process GO:0046039 72 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
organelle assembly GO:0070925 198 0.015
negative regulation of intracellular signal transduction GO:1902532 57 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
heterochromatin organization GO:0070828 25 0.014
histone lysine methylation GO:0034968 32 0.014
neuron projection guidance GO:0097485 241 0.014
fat soluble vitamin metabolic process GO:0006775 1 0.014
positive regulation of catabolic process GO:0009896 105 0.014
purine nucleoside monophosphate metabolic process GO:0009126 50 0.014
regulation of cell proliferation GO:0042127 163 0.014
establishment of localization in cell GO:0051649 402 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.014
nucleoside monophosphate metabolic process GO:0009123 52 0.014
response to endogenous stimulus GO:0009719 119 0.014
compound eye development GO:0048749 307 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
regulation of catalytic activity GO:0050790 185 0.014
response to abiotic stimulus GO:0009628 341 0.014
carboxylic acid metabolic process GO:0019752 92 0.013
single organism biosynthetic process GO:0044711 206 0.013
macromolecular complex assembly GO:0065003 256 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
axonogenesis GO:0007409 290 0.013
stem cell proliferation GO:0072089 88 0.013
eye development GO:0001654 323 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
cellular amine metabolic process GO:0044106 12 0.013
regulation of gtpase activity GO:0043087 44 0.013
protein complex biogenesis GO:0070271 201 0.013
negative regulation of cell cycle GO:0045786 116 0.012
positive regulation of nucleoside metabolic process GO:0045979 47 0.012
mitotic g2 dna damage checkpoint GO:0007095 69 0.012
anterior posterior pattern specification GO:0009952 136 0.012
response to biotic stimulus GO:0009607 294 0.012
gtp catabolic process GO:0006184 72 0.012
open tracheal system development GO:0007424 204 0.012
embryonic organ development GO:0048568 50 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
regulation of transport GO:0051049 181 0.012
regulation of hydrolase activity GO:0051336 97 0.012
regulation of neuron differentiation GO:0045664 103 0.012
axis specification GO:0009798 167 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.012
protein transport GO:0015031 155 0.012
developmental growth GO:0048589 280 0.012
brain development GO:0007420 120 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
regulation of protein localization GO:0032880 76 0.012
regulation of chromosome segregation GO:0051983 32 0.011
determination of adult lifespan GO:0008340 137 0.011
response to bacterium GO:0009617 198 0.011
respiratory system development GO:0060541 213 0.011
amine metabolic process GO:0009308 12 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.011
wing disc morphogenesis GO:0007472 344 0.011
macromolecule methylation GO:0043414 45 0.011
axon development GO:0061564 297 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
connective tissue development GO:0061448 3 0.011
compound eye morphogenesis GO:0001745 249 0.011
purine nucleoside monophosphate catabolic process GO:0009128 38 0.011
cell cycle phase transition GO:0044770 140 0.011
negative regulation of signal transduction GO:0009968 206 0.011
nucleosome organization GO:0034728 59 0.011
regulation of protein catabolic process GO:0042176 55 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
protein alkylation GO:0008213 43 0.011
metaphase anaphase transition of cell cycle GO:0044784 28 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
regulation of neural precursor cell proliferation GO:2000177 35 0.010
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.010
stem cell division GO:0017145 69 0.010
developmental programmed cell death GO:0010623 138 0.010
circulatory system development GO:0072359 82 0.010
positive regulation of gtp catabolic process GO:0033126 43 0.010
response to other organism GO:0051707 293 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
asymmetric stem cell division GO:0098722 49 0.010

RhoGAP54D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
disease of anatomical entity DOID:7 0 0.019