Drosophila melanogaster

106 known processes

cnn (Dmel_CG4832)

centrosomin

(Aliases: Dmel\CG4832,mat(2)synHK21,cen,CG4832,obv,Cnn,mat(2)syn-C,mfs,CG 4832,CNN,CG18370)

cnn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle fission GO:0048285 340 0.997
nuclear division GO:0000280 332 0.994
meiotic nuclear division GO:0007126 151 0.988
meiotic cell cycle process GO:1903046 132 0.982
pole cell formation GO:0007279 19 0.973
microtubule organizing center organization GO:0031023 168 0.970
cell division GO:0051301 248 0.967
spindle organization GO:0007051 253 0.963
pronuclear migration GO:0035046 4 0.955
oocyte differentiation GO:0009994 145 0.949
mitotic spindle organization GO:0007052 220 0.943
organelle assembly GO:0070925 198 0.929
meiotic cell cycle GO:0051321 171 0.919
axonogenesis GO:0007409 290 0.911
nuclear migration GO:0007097 20 0.892
meiotic chromosome segregation GO:0045132 59 0.891
asymmetric cell division GO:0008356 37 0.886
cell cycle phase transition GO:0044770 140 0.852
neuroblast division GO:0055057 35 0.849
negative regulation of cell cycle phase transition GO:1901988 103 0.815
spermatogenesis GO:0007283 200 0.812
fertilization GO:0009566 26 0.790
negative regulation of mitotic cell cycle GO:0045930 109 0.780
mitotic cell cycle embryonic GO:0045448 38 0.776
meiosis i GO:0007127 59 0.760
single fertilization GO:0007338 24 0.753
centriole replication GO:0007099 24 0.735
regulation of cell cycle phase transition GO:1901987 130 0.730
oocyte construction GO:0007308 112 0.702
centrosome cycle GO:0007098 137 0.677
oocyte development GO:0048599 124 0.652
establishment of nucleus localization GO:0040023 26 0.635
cytokinesis GO:0000910 90 0.634
oocyte axis specification GO:0007309 108 0.617
pole cell development GO:0007277 26 0.586
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.573
regulation of mitotic cell cycle phase transition GO:1901990 130 0.557
establishment of localization in cell GO:0051649 402 0.552
mitotic cell cycle phase transition GO:0044772 138 0.524
pole plasm protein localization GO:0007318 10 0.503
sister chromatid segregation GO:0000819 92 0.494
regulation of embryonic development GO:0045995 68 0.472
meiotic spindle organization GO:0000212 36 0.444
centrosome duplication GO:0051298 121 0.381
ras protein signal transduction GO:0007265 88 0.370
regulation of mitosis GO:0007088 56 0.326
negative regulation of cell cycle GO:0045786 116 0.319
spindle assembly GO:0051225 80 0.302
spindle assembly involved in meiosis GO:0090306 20 0.285
regulation of mitotic cell cycle GO:0007346 190 0.283
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.275
mitotic cell cycle checkpoint GO:0007093 88 0.274
mitotic nuclear division GO:0007067 213 0.272
nucleus localization GO:0051647 34 0.260
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.259
cytoskeleton dependent cytokinesis GO:0061640 81 0.247
regulation of immune response GO:0050776 118 0.227
cell maturation GO:0048469 144 0.217
oocyte anterior posterior axis specification GO:0007314 72 0.217
developmental maturation GO:0021700 172 0.214
nucleus organization GO:0006997 45 0.203
rna localization GO:0006403 115 0.195
apoptotic process GO:0006915 159 0.192
centrosome separation GO:0051299 20 0.185
regionalization GO:0003002 416 0.181
organelle localization GO:0051640 148 0.179
regulation of catabolic process GO:0009894 170 0.173
female meiosis chromosome segregation GO:0016321 33 0.173
establishment of organelle localization GO:0051656 122 0.172
cytoplasmic transport GO:0016482 130 0.170
regulation of cell cycle GO:0051726 291 0.168
growth GO:0040007 359 0.164
anterior posterior axis specification embryo GO:0008595 103 0.161
regulation of pole plasm oskar mrna localization GO:0007317 27 0.159
oocyte maturation GO:0001556 3 0.158
organonitrogen compound biosynthetic process GO:1901566 117 0.153
oocyte microtubule cytoskeleton organization GO:0016325 35 0.151
regulation of cell division GO:0051302 72 0.147
small gtpase mediated signal transduction GO:0007264 88 0.145
male meiosis GO:0007140 52 0.144
melanin metabolic process GO:0006582 47 0.143
pronuclear fusion GO:0007344 4 0.134
cellular response to chemical stimulus GO:0070887 199 0.128
chromosome organization involved in meiosis GO:0070192 10 0.123
male gamete generation GO:0048232 201 0.122
negative regulation of microtubule depolymerization GO:0007026 21 0.121
mitotic cytokinesis GO:0000281 50 0.117
mitotic sister chromatid separation GO:0051306 30 0.113
anterior posterior pattern specification GO:0009952 136 0.110
asymmetric neuroblast division GO:0055059 33 0.108
regulation of sister chromatid segregation GO:0033045 28 0.106
regulation of cell cycle process GO:0010564 181 0.104
meiosis ii GO:0007135 23 0.104
pole plasm mrna localization GO:0019094 49 0.103
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.091
pole plasm assembly GO:0007315 61 0.089
organelle fusion GO:0048284 46 0.088
regulation of cell size GO:0008361 63 0.088
microtubule polymerization or depolymerization GO:0031109 39 0.086
larval development GO:0002164 104 0.085
chromosome condensation GO:0030261 41 0.084
anterior posterior axis specification GO:0009948 109 0.084
protein complex biogenesis GO:0070271 201 0.080
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.079
protein localization GO:0008104 284 0.079
single organism membrane organization GO:0044802 93 0.079
pole plasm rna localization GO:0007316 52 0.078
regulation of meiosis GO:0040020 3 0.077
neural precursor cell proliferation GO:0061351 75 0.076
tissue death GO:0016271 102 0.074
axon development GO:0061564 297 0.073
cellular protein complex assembly GO:0043623 71 0.072
regulation of dendrite morphogenesis GO:0048814 28 0.071
cell migration GO:0016477 238 0.071
spermatid differentiation GO:0048515 114 0.070
proteolysis GO:0006508 192 0.069
regulation of compound eye cone cell fate specification GO:0042682 4 0.069
cellularization GO:0007349 90 0.069
cytoplasmic microtubule organization GO:0031122 22 0.066
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.065
centriole centriole cohesion GO:0010457 5 0.063
dorsal ventral pattern formation GO:0009953 133 0.063
membrane organization GO:0061024 112 0.061
male meiosis cytokinesis GO:0007112 26 0.059
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.058
asymmetric stem cell division GO:0098722 49 0.057
negative regulation of chromosome segregation GO:0051985 14 0.056
mitotic sister chromatid segregation GO:0000070 87 0.056
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.056
cellular amino acid metabolic process GO:0006520 61 0.055
positive regulation of immune effector process GO:0002699 28 0.055
nuclear transport GO:0051169 72 0.055
microtubule depolymerization GO:0007019 25 0.053
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.052
macromolecule catabolic process GO:0009057 161 0.052
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.051
cystoblast division GO:0007282 10 0.051
regulation of ras protein signal transduction GO:0046578 93 0.051
membrane disassembly GO:0030397 4 0.050
regulation of oocyte development GO:0060281 27 0.049
establishment of cell polarity GO:0030010 40 0.049
maternal determination of anterior posterior axis embryo GO:0008358 74 0.049
digestive tract development GO:0048565 149 0.048
negative regulation of epithelial cell proliferation GO:0050680 4 0.048
centrosome organization GO:0051297 163 0.047
attachment of spindle microtubules to kinetochore GO:0008608 5 0.047
regulation of nuclear division GO:0051783 58 0.047
embryonic morphogenesis GO:0048598 206 0.047
mitotic spindle assembly checkpoint GO:0007094 11 0.046
regulation of g2 m transition of mitotic cell cycle GO:0010389 15 0.045
cellular macromolecule localization GO:0070727 220 0.045
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.045
modification dependent protein catabolic process GO:0019941 78 0.042
axis specification GO:0009798 167 0.042
spindle assembly involved in female meiosis GO:0007056 14 0.040
embryonic axis specification GO:0000578 107 0.040
mitotic spindle checkpoint GO:0071174 11 0.040
negative regulation of mitotic sister chromatid segregation GO:0033048 13 0.040
regulation of developmental growth GO:0048638 174 0.040
positive regulation of catabolic process GO:0009896 105 0.038
regulation of mitotic sister chromatid segregation GO:0033047 28 0.038
taxis GO:0042330 304 0.037
positive regulation of macromolecule metabolic process GO:0010604 405 0.037
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 1 0.037
regulation of cellular protein catabolic process GO:1903362 44 0.036
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.035
regulation of multicellular organismal development GO:2000026 414 0.034
protein polymerization GO:0051258 42 0.034
oocyte dorsal ventral axis specification GO:0007310 34 0.034
mrna metabolic process GO:0016071 124 0.034
mitotic spindle stabilization GO:0043148 6 0.033
determination of adult lifespan GO:0008340 137 0.032
compound eye retinal cell programmed cell death GO:0046667 23 0.032
negative regulation of sister chromatid segregation GO:0033046 13 0.032
organophosphate metabolic process GO:0019637 195 0.032
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.032
mitotic centrosome separation GO:0007100 8 0.031
regulation of proteasomal protein catabolic process GO:0061136 39 0.031
meiotic sister chromatid segregation GO:0045144 6 0.031
body morphogenesis GO:0010171 2 0.031
establishment of mitochondrion localization microtubule mediated GO:0034643 6 0.031
brain development GO:0007420 120 0.031
mitotic chromosome condensation GO:0007076 22 0.031
spindle stabilization GO:0043146 14 0.030
neuron projection guidance GO:0097485 241 0.030
regulation of growth GO:0040008 233 0.030
metaphase anaphase transition of cell cycle GO:0044784 28 0.030
tripartite regional subdivision GO:0007351 103 0.030
cell proliferation GO:0008283 299 0.029
neuromuscular junction development GO:0007528 149 0.029
karyogamy GO:0000741 4 0.029
protein targeting GO:0006605 64 0.029
reproductive structure development GO:0048608 74 0.028
regulation of meiotic cell cycle GO:0051445 9 0.028
cell cell signaling involved in cell fate commitment GO:0045168 210 0.028
positive regulation of immune response GO:0050778 63 0.028
negative regulation of developmental process GO:0051093 201 0.027
purine containing compound metabolic process GO:0072521 155 0.027
vesicle localization GO:0051648 55 0.027
positive regulation of wnt signaling pathway GO:0030177 25 0.027
spindle checkpoint GO:0031577 11 0.027
regulation of intracellular transport GO:0032386 64 0.026
central nervous system development GO:0007417 201 0.026
humoral immune response GO:0006959 117 0.026
regulation of protein complex disassembly GO:0043244 29 0.026
cellular component assembly involved in morphogenesis GO:0010927 151 0.025
mitotic dna damage checkpoint GO:0044773 74 0.025
dna damage checkpoint GO:0000077 78 0.025
amide biosynthetic process GO:0043604 42 0.024
intracellular transport GO:0046907 228 0.024
response to radiation GO:0009314 155 0.024
positive regulation of response to extracellular stimulus GO:0032106 8 0.024
regulation of mitotic spindle organization GO:0060236 9 0.023
digestive tract morphogenesis GO:0048546 127 0.023
regulation of catalytic activity GO:0050790 185 0.023
regulation of hemocyte proliferation GO:0035206 37 0.023
somatic stem cell division GO:0048103 37 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
negative regulation of cell cycle process GO:0010948 109 0.022
embryonic pattern specification GO:0009880 174 0.022
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.022
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.022
immune system process GO:0002376 347 0.022
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 13 0.022
protein localization to organelle GO:0033365 82 0.022
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.022
regulation of protein catabolic process GO:0042176 55 0.022
tube development GO:0035295 244 0.022
cellular protein catabolic process GO:0044257 83 0.022
germarium derived female germ line cyst formation GO:0030727 42 0.022
regulation of chromosome segregation GO:0051983 32 0.021
localization of cell GO:0051674 257 0.021
regulation of cellular localization GO:0060341 136 0.021
establishment of spindle orientation GO:0051294 18 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.020
regulation of molecular function GO:0065009 217 0.020
regulation of transport GO:0051049 181 0.020
stem cell differentiation GO:0048863 117 0.019
negative regulation of protein depolymerization GO:1901880 23 0.019
regulation of mitotic cell cycle embryonic GO:0009794 11 0.019
regulation of immune effector process GO:0002697 52 0.019
regulation of microtubule depolymerization GO:0031114 24 0.019
microtubule polymerization GO:0046785 15 0.019
proteasomal protein catabolic process GO:0010498 59 0.019
glutamate metabolic process GO:0006536 5 0.019
phosphorylation GO:0016310 294 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.018
mitotic metaphase plate congression GO:0007080 13 0.018
digestive system development GO:0055123 149 0.018
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.018
spindle assembly involved in mitosis GO:0090307 50 0.018
establishment or maintenance of cell polarity GO:0007163 167 0.018
cellular protein localization GO:0034613 160 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.017
programmed cell death GO:0012501 257 0.017
wing disc morphogenesis GO:0007472 344 0.017
centrosome localization GO:0051642 14 0.017
spermatid development GO:0007286 98 0.017
rna polyadenylation GO:0043631 12 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
segmentation GO:0035282 207 0.017
negative regulation of cell division GO:0051782 17 0.016
centriole assembly GO:0098534 24 0.016
catabolic process GO:0009056 409 0.016
mitotic dna integrity checkpoint GO:0044774 75 0.016
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.016
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.016
regulation of localization GO:0032879 275 0.016
protein complex assembly GO:0006461 200 0.016
pigment metabolic process GO:0042440 84 0.016
regulation of reproductive process GO:2000241 54 0.016
negative regulation of nucleotide metabolic process GO:0045980 4 0.016
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.015
regulation of membrane potential GO:0042391 35 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
imaginal disc derived appendage development GO:0048737 399 0.015
intracellular mrna localization GO:0008298 66 0.015
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.015
organonitrogen compound metabolic process GO:1901564 318 0.015
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.015
cell cycle arrest GO:0007050 4 0.014
nuclear import GO:0051170 51 0.014
regulation of proteolysis GO:0030162 87 0.014
g1 s transition of mitotic cell cycle GO:0000082 31 0.014
regulation of nucleobase containing compound transport GO:0032239 4 0.014
antimicrobial humoral response GO:0019730 99 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
lateral inhibition GO:0046331 206 0.013
intracellular protein transport GO:0006886 104 0.013
regulation of protein phosphorylation GO:0001932 64 0.013
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.013
establishment of tissue polarity GO:0007164 87 0.013
negative regulation of photoreceptor cell differentiation GO:0046533 8 0.013
establishment of mitotic spindle localization GO:0040001 17 0.013
single organism catabolic process GO:0044712 228 0.013
regulation of ubiquitin protein transferase activity GO:0051438 4 0.013
axon guidance GO:0007411 233 0.013
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
positive regulation of cell cycle GO:0045787 43 0.012
positive regulation of nucleotide catabolic process GO:0030813 46 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
microtubule nucleation GO:0007020 8 0.012
nuclear envelope organization GO:0006998 7 0.012
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.012
cellular amide metabolic process GO:0043603 80 0.012
regulation of mitotic sister chromatid separation GO:0010965 28 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
gland development GO:0048732 191 0.012
regulation of cytoplasmic transport GO:1903649 47 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
g2 m transition of mitotic cell cycle GO:0000086 19 0.011
protein heterooligomerization GO:0051291 4 0.011
cell fate determination GO:0001709 91 0.011
developmental growth GO:0048589 280 0.011
germ line cyst formation GO:0048134 44 0.011
negative regulation of phosphatase activity GO:0010923 3 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.011
telencephalon development GO:0021537 2 0.011
regulation of spindle organization GO:0090224 17 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
neuronal stem cell division GO:0036445 35 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
forebrain development GO:0030900 2 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
maintenance of protein location in cell GO:0032507 26 0.011
establishment of spindle localization GO:0051293 22 0.010
negative regulation of protein complex disassembly GO:0043242 23 0.010
biological adhesion GO:0022610 138 0.010
neuron recognition GO:0008038 101 0.010
spindle localization GO:0051653 22 0.010
positive regulation of transcription factor import into nucleus GO:0042993 19 0.010
regulation of dendrite development GO:0050773 37 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
regulation of protein localization GO:0032880 76 0.010

cnn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
large intestine cancer DOID:5672 0 0.023
gastrointestinal system cancer DOID:3119 0 0.023
intestinal cancer DOID:10155 0 0.023
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.023
colorectal cancer DOID:9256 0 0.023
disease of anatomical entity DOID:7 0 0.011