Drosophila melanogaster

111 known processes

Sxl (Dmel_CG18350)

Sex lethal

(Aliases: Su(da),Dmel\CG18350,fs(1)K1274,Sx1,l(1)6Fa,SXL,CG33070,dSXL,Mex156,CG18350,DmSxl,fs(1)M106,sxl,SxlPe,SxL,Fl,Sxl-1 Sxl-2,SxlPm)

Sxl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
germarium derived egg chamber formation GO:0007293 101 0.980
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.886
oocyte microtubule cytoskeleton organization GO:0016325 35 0.793
oocyte differentiation GO:0009994 145 0.755
female germ line cyst formation GO:0048135 42 0.703
germarium derived female germ line cyst formation GO:0030727 42 0.698
germ line cyst formation GO:0048134 44 0.516
regulation of meiosis GO:0040020 3 0.482
establishment of organelle localization GO:0051656 122 0.479
sex determination GO:0007530 18 0.474
cell proliferation GO:0008283 299 0.382
Fly
meiosis i GO:0007127 59 0.353
organelle localization GO:0051640 148 0.294
cell fate determination GO:0001709 91 0.231
ovarian follicle cell stalk formation GO:0030713 17 0.217
chromatin modification GO:0016568 147 0.169
germarium derived oocyte fate determination GO:0007294 26 0.161
germarium derived female germ line cyst encapsulation GO:0030708 8 0.161
oocyte construction GO:0007308 112 0.149
oocyte development GO:0048599 124 0.148
immune system process GO:0002376 347 0.143
reproductive system development GO:0061458 74 0.134
negative regulation of meiotic cell cycle GO:0051447 2 0.129
fusome organization GO:0045478 13 0.126
positive regulation of macromolecule metabolic process GO:0010604 405 0.125
imaginal disc derived female genitalia development GO:0007486 6 0.114
negative regulation of biosynthetic process GO:0009890 277 0.112
localization of cell GO:0051674 257 0.102
axon choice point recognition GO:0016198 26 0.098
ovarian fusome organization GO:0030723 11 0.097
immune response GO:0006955 246 0.094
germ cell migration GO:0008354 43 0.092
germarium derived oocyte differentiation GO:0030706 29 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.086
female sex differentiation GO:0046660 20 0.084
oocyte axis specification GO:0007309 108 0.083
chromosome organization GO:0051276 360 0.074
cell migration GO:0016477 238 0.072
developmental maturation GO:0021700 172 0.067
morphogenesis of follicular epithelium GO:0016333 36 0.067
regulation of response to external stimulus GO:0032101 115 0.063
regulation of synapse structure and activity GO:0050803 128 0.061
synaptic vesicle transport GO:0048489 50 0.061
regulation of phosphate metabolic process GO:0019220 210 0.056
neurological system process GO:0050877 358 0.056
positive regulation of cellular biosynthetic process GO:0031328 316 0.055
intercellular bridge organization GO:0043063 14 0.053
cystoblast division GO:0007282 10 0.051
nuclear migration GO:0007097 20 0.050
stem cell differentiation GO:0048863 117 0.048
axon midline choice point recognition GO:0016199 26 0.047
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.046
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.045
nucleus localization GO:0051647 34 0.043
growth GO:0040007 359 0.042
cell motility GO:0048870 251 0.039
embryo development ending in birth or egg hatching GO:0009792 152 0.038
histone h4 k16 acetylation GO:0043984 4 0.037
molting cycle GO:0042303 56 0.036
carbohydrate derivative metabolic process GO:1901135 217 0.036
synaptic vesicle localization GO:0097479 53 0.035
chromatin silencing GO:0006342 76 0.035
anterior posterior axis specification GO:0009948 109 0.034
establishment of protein localization GO:0045184 163 0.034
protein localization GO:0008104 284 0.034
body morphogenesis GO:0010171 2 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.033
defense response GO:0006952 300 0.032
Fly
multi organism reproductive behavior GO:0044705 121 0.031
regulation of cell differentiation GO:0045595 302 0.030
establishment of localization in cell GO:0051649 402 0.030
meiotic nuclear division GO:0007126 151 0.030
developmental growth GO:0048589 280 0.030
protein complex biogenesis GO:0070271 201 0.029
regulation of cell division GO:0051302 72 0.027
positive regulation of biosynthetic process GO:0009891 316 0.027
female germ line cyst encapsulation GO:0048139 8 0.027
stem cell division GO:0017145 69 0.026
organic substance transport GO:0071702 257 0.026
chromatin organization GO:0006325 207 0.026
regulation of hemocyte proliferation GO:0035206 37 0.026
intracellular signal transduction GO:0035556 300 0.026
protein transport GO:0015031 155 0.026
cellular catabolic process GO:0044248 372 0.026
actin filament organization GO:0007015 126 0.025
negative regulation of chromatin silencing GO:0031936 9 0.024
sex differentiation GO:0007548 81 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
membrane organization GO:0061024 112 0.023
response to organic substance GO:0010033 284 0.023
positive regulation of mitotic cell cycle GO:0045931 34 0.023
regulation of intracellular transport GO:0032386 64 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.022
cellular protein complex assembly GO:0043623 71 0.022
exocrine system development GO:0035272 162 0.022
dna metabolic process GO:0006259 227 0.022
mitotic spindle organization GO:0007052 220 0.021
meiotic cell cycle GO:0051321 171 0.021
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.021
germ line cyst encapsulation GO:0048138 8 0.020
vesicle organization GO:0016050 44 0.020
establishment of vesicle localization GO:0051650 51 0.019
dna alkylation GO:0006305 4 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.019
establishment of planar polarity GO:0001736 87 0.019
establishment or maintenance of cell polarity GO:0007163 167 0.019
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.019
positive regulation of phosphorylation GO:0042327 87 0.018
anatomical structure homeostasis GO:0060249 97 0.018
stem cell maintenance GO:0019827 67 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
meiotic cell cycle process GO:1903046 132 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.017
hindgut morphogenesis GO:0007442 58 0.017
synapse assembly GO:0007416 143 0.016
karyosome formation GO:0030717 22 0.016
regulation of transcription factor import into nucleus GO:0042990 22 0.016
homeostatic process GO:0042592 199 0.016
small molecule metabolic process GO:0044281 305 0.016
regulation of immune response GO:0050776 118 0.016
regulation of synapse organization GO:0050807 110 0.015
organonitrogen compound metabolic process GO:1901564 318 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
actin filament based process GO:0030029 220 0.015
regulation of meiotic cell cycle GO:0051445 9 0.015
germline ring canal formation GO:0030725 13 0.015
negative regulation of phosphatase activity GO:0010923 3 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
cell division GO:0051301 248 0.015
positive regulation of molecular function GO:0044093 136 0.014
ameboidal type cell migration GO:0001667 151 0.014
organic substance catabolic process GO:1901575 308 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
death GO:0016265 284 0.014
synapse organization GO:0050808 196 0.014
intracellular protein transport GO:0006886 104 0.014
regulation of gene expression epigenetic GO:0040029 128 0.013
developmental programmed cell death GO:0010623 138 0.013
cellular protein modification process GO:0006464 438 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
chaeta development GO:0022416 97 0.013
cell death GO:0008219 279 0.013
establishment of synaptic vesicle localization GO:0097480 50 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
cell aging GO:0007569 2 0.013
genitalia development GO:0048806 26 0.013
stem cell proliferation GO:0072089 88 0.013
autophagic cell death GO:0048102 83 0.012
positive regulation of cell cycle process GO:0090068 28 0.012
female germline ring canal formation GO:0007301 9 0.012
carbohydrate metabolic process GO:0005975 82 0.012
histone h3 k9 modification GO:0061647 12 0.012
catabolic process GO:0009056 409 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
mrna splicing via spliceosome GO:0000398 73 0.011
gene silencing by rna GO:0031047 57 0.011
generation of precursor metabolites and energy GO:0006091 42 0.011
response to radiation GO:0009314 155 0.011
spindle organization GO:0007051 253 0.011
protein homooligomerization GO:0051260 7 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 9 0.011
cellular protein localization GO:0034613 160 0.011
immune system development GO:0002520 57 0.011
protein localization to organelle GO:0033365 82 0.011
tripartite regional subdivision GO:0007351 103 0.011
female genitalia development GO:0030540 6 0.010
response to ecdysone GO:0035075 34 0.010
glucan biosynthetic process GO:0009250 2 0.010
ion transport GO:0006811 145 0.010
chitin based cuticle sclerotization GO:0007593 19 0.010
positive regulation of binding GO:0051099 4 0.010

Sxl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org