Drosophila melanogaster

51 known processes

Sod (Dmel_CG11793)

Superoxide dismutase

(Aliases: CG11793,ZnSod,sod,Sod1,To,l(3)108,Cu/Zn sod,CuZnSOD,cSOD,SOD,sod1,Sod-1,CuSOD,Cu/Zn SOD,G,SOD1,To-1,Cu-Zn SOD,Dmel\CG11793,Cu[2+]/Zn[2+]SOD,Cu/ZnSOD,l(3)68Af',Zn Sod,cSod,l(3)G,SOD-1,Cu/Zn superoxide dismutase,CuZn-SOD,CuZn SOD,Zn-SOD,Cu)

Sod biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to oxidative stress GO:0006979 86 1.000
cellular response to oxidative stress GO:0034599 28 0.997
cellular response to reactive oxygen species GO:0034614 14 0.991
response to reactive oxygen species GO:0000302 24 0.951
response to hydrogen peroxide GO:0042542 11 0.924
Mouse
programmed cell death GO:0012501 257 0.792
Human Mouse Rat
response to oxygen containing compound GO:1901700 200 0.722
homeostatic process GO:0042592 199 0.707
Yeast Zebrafish Mouse
learning or memory GO:0007611 141 0.686
age dependent response to oxidative stress GO:0001306 3 0.653
response to organic substance GO:0010033 284 0.603
Human Zebrafish Mouse Rat
determination of adult lifespan GO:0008340 137 0.589
single organism biosynthetic process GO:0044711 206 0.574
Human
pigmentation GO:0043473 75 0.540
oxoacid metabolic process GO:0043436 103 0.532
Mouse
regulation of multicellular organismal development GO:2000026 414 0.528
cellular lipid metabolic process GO:0044255 83 0.472
multicellular organismal aging GO:0010259 140 0.472
small molecule metabolic process GO:0044281 305 0.469
Human Mouse
paracrine signaling GO:0038001 7 0.465
response to abiotic stimulus GO:0009628 341 0.457
Mouse
regulation of catabolic process GO:0009894 170 0.449
carboxylic acid metabolic process GO:0019752 92 0.439
Mouse
response to metal ion GO:0010038 23 0.439
Zebrafish Rat
cellular amide metabolic process GO:0043603 80 0.435
Mouse
oxidation reduction process GO:0055114 123 0.423
regulation of apoptotic process GO:0042981 130 0.395
Human Mouse Rat
hydrogen peroxide catabolic process GO:0042744 6 0.365
death GO:0016265 284 0.333
Human Mouse Rat
aging GO:0007568 143 0.328
positive regulation of macromolecule metabolic process GO:0010604 405 0.315
Yeast Mouse
organophosphate biosynthetic process GO:0090407 46 0.293
imaginal disc derived appendage morphogenesis GO:0035114 395 0.256
developmental programmed cell death GO:0010623 138 0.242
epithelial cell differentiation GO:0030855 322 0.242
Mouse
organic acid metabolic process GO:0006082 103 0.240
Mouse
cellular response to chemical stimulus GO:0070887 199 0.235
regulation of cell differentiation GO:0045595 302 0.225
regulation of cell death GO:0010941 173 0.206
Human Mouse Rat
lipid metabolic process GO:0006629 121 0.201
Human
neurological system process GO:0050877 358 0.197
Mouse
response to radiation GO:0009314 155 0.190
cellular response to dna damage stimulus GO:0006974 223 0.184
appendage development GO:0048736 401 0.173
regulation of cellular catabolic process GO:0031329 157 0.170
cell death GO:0008219 279 0.163
Human Mouse Rat
cation transport GO:0006812 110 0.162
negative regulation of apoptotic process GO:0043066 63 0.154
Mouse Rat
intracellular signal transduction GO:0035556 300 0.150
Human Mouse
age dependent general metabolic decline GO:0007571 3 0.142
organophosphate metabolic process GO:0019637 195 0.138
Human
localization of cell GO:0051674 257 0.136
regulation of catalytic activity GO:0050790 185 0.135
Human Mouse Rat
intracellular transport GO:0046907 228 0.135
Mouse
cell aging GO:0007569 2 0.131
Human Yeast
immune system process GO:0002376 347 0.127
Mouse
ion transport GO:0006811 145 0.123
reactive oxygen species metabolic process GO:0072593 22 0.123
establishment of localization in cell GO:0051649 402 0.123
Mouse
negative regulation of cell differentiation GO:0045596 143 0.122
single organism intracellular transport GO:1902582 207 0.121
Mouse
protein complex assembly GO:0006461 200 0.119
regulation of molecular function GO:0065009 217 0.115
Human Yeast Mouse Rat
cell redox homeostasis GO:0045454 5 0.107
cellular response to hydrogen peroxide GO:0070301 7 0.101
tissue death GO:0016271 102 0.099
negative regulation of programmed cell death GO:0043069 72 0.093
Mouse Rat
defense response GO:0006952 300 0.088
regulation of cellular response to oxidative stress GO:1900407 4 0.088
Human
immune system development GO:0002520 57 0.086
proteolysis GO:0006508 192 0.085
response to oxygen radical GO:0000305 3 0.082
catabolic process GO:0009056 409 0.081
regulation of phosphorus metabolic process GO:0051174 210 0.078
Human Mouse
molting cycle GO:0042303 56 0.076
cognition GO:0050890 141 0.076
cell type specific apoptotic process GO:0097285 38 0.075
Mouse
protein complex biogenesis GO:0070271 201 0.075
lipid biosynthetic process GO:0008610 46 0.074
Human
single organism behavior GO:0044708 391 0.070
cellular catabolic process GO:0044248 372 0.070
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.069
Yeast
appendage morphogenesis GO:0035107 397 0.068
pigment metabolic process GO:0042440 84 0.067
response to temperature stimulus GO:0009266 106 0.067
Mouse
positive regulation of intracellular signal transduction GO:1902533 116 0.066
Human Mouse
peptide metabolic process GO:0006518 80 0.064
Mouse
glutathione metabolic process GO:0006749 37 0.064
Mouse
organonitrogen compound metabolic process GO:1901564 318 0.064
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.061
Yeast
adult behavior GO:0030534 137 0.060
regulation of intracellular signal transduction GO:1902531 236 0.058
Human Mouse
regulation of proteolysis GO:0030162 87 0.056
cell motility GO:0048870 251 0.056
response to inorganic substance GO:0010035 44 0.056
cell migration GO:0016477 238 0.055
organic hydroxy compound metabolic process GO:1901615 83 0.055
Human
intrinsic apoptotic signaling pathway GO:0097193 16 0.055
Human
apoptotic process GO:0006915 159 0.055
Human Mouse Rat
developmental pigmentation GO:0048066 68 0.052
positive regulation of catalytic activity GO:0043085 118 0.052
Human Mouse Rat
macromolecular complex assembly GO:0065003 256 0.051
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.049
Human
hydrogen peroxide metabolic process GO:0042743 6 0.047
Human Mouse Rat
positive regulation of molecular function GO:0044093 136 0.046
Human Yeast Mouse Rat
tissue morphogenesis GO:0048729 297 0.045
reproductive system development GO:0061458 74 0.045
Mouse
cellular amino acid metabolic process GO:0006520 61 0.044
Mouse
imaginal disc derived appendage development GO:0048737 399 0.044
larval development GO:0002164 104 0.044
organonitrogen compound biosynthetic process GO:1901566 117 0.043
regulation of protein metabolic process GO:0051246 256 0.042
Human Mouse
organic substance transport GO:0071702 257 0.042
endocytosis GO:0006897 310 0.042
negative regulation of molecular function GO:0044092 51 0.041
regulation of anatomical structure size GO:0090066 163 0.040
Mouse
salivary gland cell autophagic cell death GO:0035071 83 0.040
inorganic cation transmembrane transport GO:0098662 61 0.039
response to external biotic stimulus GO:0043207 293 0.039
metal ion transport GO:0030001 74 0.039
immune response GO:0006955 246 0.039
positive regulation of multicellular organismal process GO:0051240 143 0.038
Human
positive regulation of signaling GO:0023056 243 0.038
Human Mouse
membrane organization GO:0061024 112 0.037
Mouse
cellular amine metabolic process GO:0044106 12 0.036
nucleotide metabolic process GO:0009117 161 0.036
Human
nucleoside phosphate metabolic process GO:0006753 162 0.035
Human
sex differentiation GO:0007548 81 0.035
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 27 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.033
positive regulation of cell communication GO:0010647 250 0.033
Human Mouse
adult locomotory behavior GO:0008344 76 0.033
regulation of hydrolase activity GO:0051336 97 0.032
Human
energy derivation by oxidation of organic compounds GO:0015980 32 0.032
Yeast
regulation of autophagy GO:0010506 62 0.031
regulation of localization GO:0032879 275 0.031
regulation of endopeptidase activity GO:0052548 36 0.031
hemopoiesis GO:0030097 46 0.031
amine metabolic process GO:0009308 12 0.030
single organism catabolic process GO:0044712 228 0.030
Human
response to biotic stimulus GO:0009607 294 0.030
sperm mitochondrion organization GO:0030382 7 0.030
nucleobase containing small molecule metabolic process GO:0055086 174 0.029
Human
regulation of cellular localization GO:0060341 136 0.029
negative regulation of cell death GO:0060548 81 0.029
Mouse Rat
response to other organism GO:0051707 293 0.029
transmembrane transport GO:0055085 139 0.029
vesicle mediated transport GO:0016192 381 0.028
intracellular protein transport GO:0006886 104 0.028
regulation of programmed cell death GO:0043067 152 0.028
Human Mouse Rat
regulation of anatomical structure morphogenesis GO:0022603 242 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
Human Mouse
regulation of cell development GO:0060284 215 0.027
histolysis GO:0007559 102 0.026
internal protein amino acid acetylation GO:0006475 38 0.026
inorganic ion transmembrane transport GO:0098660 73 0.025
cellular modified amino acid metabolic process GO:0006575 45 0.025
Mouse
autophagic cell death GO:0048102 83 0.025
hematopoietic or lymphoid organ development GO:0048534 57 0.025
cellular respiration GO:0045333 26 0.024
Yeast
regulation of neurogenesis GO:0050767 158 0.024
brain development GO:0007420 120 0.024
salivary gland histolysis GO:0035070 88 0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.023
gonad development GO:0008406 50 0.023
Mouse
response to extracellular stimulus GO:0009991 116 0.022
Rat
positive regulation of cell death GO:0010942 69 0.022
Human
cellular protein complex assembly GO:0043623 71 0.021
positive regulation of catabolic process GO:0009896 105 0.021
maintenance of location GO:0051235 73 0.021
developmental cell growth GO:0048588 52 0.020
signal transduction by phosphorylation GO:0023014 107 0.020
Mouse
eye pigmentation GO:0048069 43 0.019
mitotic nuclear division GO:0007067 213 0.019
positive regulation of developmental process GO:0051094 143 0.019
chromatin organization GO:0006325 207 0.019
head development GO:0060322 135 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
Yeast
negative regulation of developmental process GO:0051093 201 0.019
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.019
cell proliferation GO:0008283 299 0.019
regulation of peptidase activity GO:0052547 39 0.018
cellular response to extracellular stimulus GO:0031668 64 0.018
cell adhesion GO:0007155 136 0.018
positive regulation of apoptotic signaling pathway GO:2001235 4 0.018
Human
response to alcohol GO:0097305 95 0.018
Mouse
reproductive structure development GO:0048608 74 0.018
Mouse
regulation of lipid metabolic process GO:0019216 15 0.017
Human
alcohol metabolic process GO:0006066 25 0.017
Human
cellular macromolecule catabolic process GO:0044265 136 0.017
enzyme linked receptor protein signaling pathway GO:0007167 179 0.017
regulation of mapk cascade GO:0043408 92 0.017
Mouse
ion transmembrane transport GO:0034220 122 0.017
generation of precursor metabolites and energy GO:0006091 42 0.016
Yeast
cation transmembrane transport GO:0098655 88 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
response to heat GO:0009408 63 0.016
Mouse
exocrine system development GO:0035272 162 0.016
wing disc morphogenesis GO:0007472 344 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
Human Mouse
response to organic cyclic compound GO:0014070 89 0.016
Rat
pigment cell differentiation GO:0050931 3 0.015
ribonucleoside biosynthetic process GO:0042455 3 0.015
regulation of rac gtpase activity GO:0032314 1 0.015
Human
response to cold GO:0009409 13 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
establishment or maintenance of cell polarity GO:0007163 167 0.015
regulation of cell cycle GO:0051726 291 0.015
positive regulation of programmed cell death GO:0043068 62 0.015
Human
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.015
developmental maturation GO:0021700 172 0.015
actin cytoskeleton organization GO:0030036 206 0.015
lipid localization GO:0010876 54 0.014
heterocycle catabolic process GO:0046700 166 0.014
Human
cellular biogenic amine metabolic process GO:0006576 9 0.014
cellular response to external stimulus GO:0071496 66 0.014
cytoplasmic transport GO:0016482 130 0.014
phagocytosis GO:0006909 215 0.013
lateral inhibition GO:0046331 206 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
Yeast
regulation of intracellular transport GO:0032386 64 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
Human Mouse
organic substance catabolic process GO:1901575 308 0.013
Human
development of primary sexual characteristics GO:0045137 50 0.013
Mouse
negative regulation of cell development GO:0010721 62 0.013
response to endogenous stimulus GO:0009719 119 0.013
Rat
positive regulation of apoptotic process GO:0043065 47 0.013
Human
single organism carbohydrate metabolic process GO:0044723 72 0.012
pyridine containing compound metabolic process GO:0072524 3 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
Yeast
anatomical structure homeostasis GO:0060249 97 0.012
Zebrafish Mouse
tissue migration GO:0090130 155 0.012
regulation of protein transport GO:0051223 57 0.012
positive regulation of signal transduction GO:0009967 223 0.012
Human Mouse
single organism cellular localization GO:1902580 180 0.012
organic hydroxy compound biosynthetic process GO:1901617 21 0.012
Human
response to bacterium GO:0009617 198 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
Yeast
cellular response to arsenic containing substance GO:0071243 6 0.012
glycerolipid metabolic process GO:0046486 34 0.012
muscle contraction GO:0006936 13 0.012
Mouse
phosphorylation GO:0016310 294 0.011
Human Mouse
positive regulation of phosphate metabolic process GO:0045937 139 0.011
Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.011
Human
regulation of cellular amine metabolic process GO:0033238 3 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
protein transport GO:0015031 155 0.011
spermatogenesis GO:0007283 200 0.011
Mouse
regulation of cytoplasmic transport GO:1903649 47 0.011
mapk cascade GO:0000165 107 0.011
Mouse
regulation of protein modification process GO:0031399 112 0.011
Human Mouse
purine ribonucleotide catabolic process GO:0009154 109 0.010
Human
response to monosaccharide GO:0034284 4 0.010
establishment of protein localization GO:0045184 163 0.010
regulation of transport GO:0051049 181 0.010
regulation of phosphorylation GO:0042325 147 0.010
Human Mouse
negative regulation of signaling GO:0023057 219 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
Human

Sod disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.088
carbohydrate metabolism disease DOID:0050013 0 0.088
glucose metabolism disease DOID:4194 0 0.088
acquired metabolic disease DOID:0060158 0 0.088
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.029