Drosophila melanogaster

72 known processes

CSN7 (Dmel_CG2038)

COP9 complex homolog subunit 7

(Aliases: CSN7b,Dmel\CG2038,CG2038,csn7,CH7,Dch7)

CSN7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cullin deneddylation GO:0010388 3 0.978
Human
protein deneddylation GO:0000338 8 0.836
mitotic cell cycle checkpoint GO:0007093 88 0.425
mitotic dna integrity checkpoint GO:0044774 75 0.402
cellular response to dna damage stimulus GO:0006974 223 0.358
mitotic dna damage checkpoint GO:0044773 74 0.340
mitotic g2 dna damage checkpoint GO:0007095 69 0.335
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.320
mitotic g2 m transition checkpoint GO:0044818 70 0.319
modification dependent macromolecule catabolic process GO:0043632 79 0.280
negative regulation of cell cycle phase transition GO:1901988 103 0.272
g2 dna damage checkpoint GO:0031572 69 0.250
protein modification by small protein removal GO:0070646 28 0.244
negative regulation of cell cycle process GO:0010948 109 0.220
negative regulation of mitotic cell cycle GO:0045930 109 0.200
cellular protein modification process GO:0006464 438 0.197
cell cycle phase transition GO:0044770 140 0.185
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.179
protein ubiquitination GO:0016567 70 0.159
cellular catabolic process GO:0044248 372 0.141
protein modification process GO:0036211 438 0.137
mitotic spindle organization GO:0007052 220 0.128
macromolecule catabolic process GO:0009057 161 0.126
regulation of mitotic cell cycle GO:0007346 190 0.124
positive regulation of gene expression GO:0010628 290 0.109
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.104
protein modification by small protein conjugation or removal GO:0070647 106 0.102
cell cycle checkpoint GO:0000075 95 0.097
modification dependent protein catabolic process GO:0019941 78 0.092
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.088
positive regulation of macromolecule metabolic process GO:0010604 405 0.084
histone modification GO:0016570 106 0.083
catabolic process GO:0009056 409 0.081
organic substance catabolic process GO:1901575 308 0.081
mrna cis splicing via spliceosome GO:0045292 1 0.079
regulation of mitotic cell cycle phase transition GO:1901990 130 0.078
cellular macromolecule catabolic process GO:0044265 136 0.078
posttranscriptional regulation of gene expression GO:0010608 145 0.077
regulation of catabolic process GO:0009894 170 0.076
positive regulation of nucleic acid templated transcription GO:1903508 266 0.075
positive regulation of transcription dna templated GO:0045893 266 0.072
chromosome organization GO:0051276 360 0.072
regulation of protein metabolic process GO:0051246 256 0.069
positive regulation of rna biosynthetic process GO:1902680 266 0.068
chromatin modification GO:0016568 147 0.068
ubiquitin dependent protein catabolic process GO:0006511 78 0.063
positive regulation of cellular biosynthetic process GO:0031328 316 0.063
regulation of cellular catabolic process GO:0031329 157 0.062
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.061
positive regulation of response to stimulus GO:0048584 323 0.060
cellular protein catabolic process GO:0044257 83 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.055
negative regulation of gene expression GO:0010629 387 0.052
positive regulation of rna metabolic process GO:0051254 271 0.051
regulation of proteolysis GO:0030162 87 0.050
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.048
dna damage checkpoint GO:0000077 78 0.045
regulation of cell cycle phase transition GO:1901987 130 0.045
regulation of cell cycle process GO:0010564 181 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.042
dna templated transcription initiation GO:0006352 25 0.042
proteolysis GO:0006508 192 0.039
negative regulation of rna metabolic process GO:0051253 251 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.037
cell projection assembly GO:0030031 94 0.035
spindle organization GO:0007051 253 0.035
dna integrity checkpoint GO:0031570 81 0.034
phagocytosis GO:0006909 215 0.034
organonitrogen compound metabolic process GO:1901564 318 0.033
negative regulation of cell proliferation GO:0008285 69 0.033
negative regulation of cell cycle GO:0045786 116 0.032
protein catabolic process GO:0030163 101 0.031
regulation of cellular protein metabolic process GO:0032268 243 0.030
organelle assembly GO:0070925 198 0.029
regulation of cellular component biogenesis GO:0044087 201 0.029
protein modification by small protein conjugation GO:0032446 79 0.028
intraspecies interaction between organisms GO:0051703 4 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.026
regulation of cellular protein catabolic process GO:1903362 44 0.025
methylation GO:0032259 47 0.025
heterocycle catabolic process GO:0046700 166 0.024
purine ribonucleotide catabolic process GO:0009154 109 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
establishment of nucleus localization GO:0040023 26 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.022
lateral inhibition GO:0046331 206 0.022
immune response GO:0006955 246 0.022
endocytosis GO:0006897 310 0.022
aromatic compound catabolic process GO:0019439 166 0.022
ribonucleoside triphosphate catabolic process GO:0009203 108 0.022
positive regulation of biosynthetic process GO:0009891 316 0.022
eye photoreceptor cell differentiation GO:0001754 145 0.021
positive regulation of signaling GO:0023056 243 0.021
regulation of localization GO:0032879 275 0.020
chromatin organization GO:0006325 207 0.020
proteasomal protein catabolic process GO:0010498 59 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
negative regulation of cellular catabolic process GO:0031330 34 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.020
covalent chromatin modification GO:0016569 106 0.020
glycosyl compound catabolic process GO:1901658 112 0.020
response to heat GO:0009408 63 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.019
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.019
protein alkylation GO:0008213 43 0.019
cell division GO:0051301 248 0.019
nucleobase containing compound catabolic process GO:0034655 165 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
regulation of smoothened signaling pathway GO:0008589 28 0.018
smoothened signaling pathway GO:0007224 49 0.018
regulation of hydrolase activity GO:0051336 97 0.018
cytokinesis GO:0000910 90 0.018
sister chromatid segregation GO:0000819 92 0.018
nucleoside metabolic process GO:0009116 127 0.017
single organism catabolic process GO:0044712 228 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
regulation of molecular function GO:0065009 217 0.017
cytoskeleton dependent cytokinesis GO:0061640 81 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.017
chromosome segregation GO:0007059 157 0.017
cellular response to heat GO:0034605 24 0.017
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
regulation of erbb signaling pathway GO:1901184 42 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
negative regulation of molecular function GO:0044092 51 0.016
purine containing compound metabolic process GO:0072521 155 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
purine containing compound catabolic process GO:0072523 112 0.015
positive regulation of signal transduction GO:0009967 223 0.015
regulation of protein stability GO:0031647 43 0.015
regulation of protein modification process GO:0031399 112 0.015
positive regulation of catabolic process GO:0009896 105 0.014
molting cycle GO:0042303 56 0.014
protein neddylation GO:0045116 5 0.014
response to external biotic stimulus GO:0043207 293 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
centrosome organization GO:0051297 163 0.014
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
intracellular signal transduction GO:0035556 300 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
positive regulation of proteolysis GO:0045862 52 0.013
protein dna complex subunit organization GO:0071824 86 0.013
regulation of dna templated transcription elongation GO:0032784 17 0.013
positive regulation of cell communication GO:0010647 250 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
organelle fission GO:0048285 340 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
immune system process GO:0002376 347 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
regulation of protein catabolic process GO:0042176 55 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
positive regulation of cell motility GO:2000147 3 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 17 0.011
mrna catabolic process GO:0006402 33 0.011
spinal cord development GO:0021510 1 0.011
regulation of neuroblast proliferation GO:1902692 34 0.011
appendage development GO:0048736 401 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
nucleoside catabolic process GO:0009164 112 0.011
rna interference GO:0016246 27 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
cellular response to organic substance GO:0071310 132 0.011
camera type eye development GO:0043010 4 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
organophosphate catabolic process GO:0046434 112 0.010
histone methylation GO:0016571 40 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.010
cilium organization GO:0044782 41 0.010
regulation of cell cycle GO:0051726 291 0.010
ras protein signal transduction GO:0007265 88 0.010
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010

CSN7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.011
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011