Drosophila melanogaster

98 known processes

MKP-4 (Dmel_CG14211)

MAPK Phosphatase 4

(Aliases: Mkp4,CG14211,DMKP-4,Dmel\CG14211)

MKP-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.086
imaginal disc derived appendage development GO:0048737 399 0.084
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.074
wing disc morphogenesis GO:0007472 344 0.071
appendage morphogenesis GO:0035107 397 0.059
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.059
rna processing GO:0006396 147 0.058
defense response GO:0006952 300 0.057
post embryonic appendage morphogenesis GO:0035120 385 0.052
transcription from rna polymerase ii promoter GO:0006366 368 0.049
organonitrogen compound metabolic process GO:1901564 318 0.044
immune response GO:0006955 246 0.041
response to other organism GO:0051707 293 0.041
negative regulation of gene expression GO:0010629 387 0.039
negative regulation of cellular metabolic process GO:0031324 382 0.039
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
response to biotic stimulus GO:0009607 294 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.034
regulation of cell cycle GO:0051726 291 0.034
phosphorylation GO:0016310 294 0.034
appendage development GO:0048736 401 0.032
cellular amino acid metabolic process GO:0006520 61 0.031
negative regulation of biosynthetic process GO:0009890 277 0.031
cellular protein modification process GO:0006464 438 0.031
signal transduction by phosphorylation GO:0023014 107 0.029
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
regulation of response to stress GO:0080134 200 0.029
immune system process GO:0002376 347 0.029
gene silencing GO:0016458 138 0.028
innate immune response GO:0045087 144 0.028
positive regulation of response to stimulus GO:0048584 323 0.027
cellular response to dna damage stimulus GO:0006974 223 0.026
macromolecule catabolic process GO:0009057 161 0.026
catabolic process GO:0009056 409 0.026
regulation of immune system process GO:0002682 176 0.026
positive regulation of cell motility GO:2000147 3 0.025
body morphogenesis GO:0010171 2 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
multi organism behavior GO:0051705 175 0.024
heterocycle catabolic process GO:0046700 166 0.023
positive regulation of cell communication GO:0010647 250 0.023
cellular macromolecule catabolic process GO:0044265 136 0.023
negative regulation of signal transduction GO:0009968 206 0.023
amine metabolic process GO:0009308 12 0.022
positive regulation of histone deacetylation GO:0031065 2 0.022
regulation of cell substrate adhesion GO:0010810 2 0.022
positive regulation of immune response GO:0050778 63 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
spermatogenesis GO:0007283 200 0.021
regulation of gene expression epigenetic GO:0040029 128 0.021
oxoacid metabolic process GO:0043436 103 0.021
posttranscriptional regulation of gene expression GO:0010608 145 0.021
stem cell proliferation GO:0072089 88 0.021
mrna splicing via spliceosome GO:0000398 73 0.021
negative regulation of developmental process GO:0051093 201 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
positive regulation of signaling GO:0023056 243 0.020
response to oxidative stress GO:0006979 86 0.020
response to wounding GO:0009611 94 0.019
ncrna metabolic process GO:0034660 43 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
meiotic cell cycle GO:0051321 171 0.019
organic substance catabolic process GO:1901575 308 0.019
organic cyclic compound catabolic process GO:1901361 168 0.018
regulation of protein metabolic process GO:0051246 256 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
positive regulation of immune system process GO:0002684 68 0.018
cell cycle phase transition GO:0044770 140 0.018
neurological system process GO:0050877 358 0.018
g protein coupled receptor signaling pathway GO:0007186 136 0.017
positive regulation of multicellular organismal process GO:0051240 143 0.017
vitamin biosynthetic process GO:0009110 1 0.017
vesicle mediated transport GO:0016192 381 0.017
single organism behavior GO:0044708 391 0.017
positive regulation of cell migration GO:0030335 2 0.017
negative regulation of cell differentiation GO:0045596 143 0.016
aromatic compound catabolic process GO:0019439 166 0.016
larval development GO:0002164 104 0.016
mrna metabolic process GO:0016071 124 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
eye development GO:0001654 323 0.016
regulation of cell differentiation GO:0045595 302 0.016
cellular amine metabolic process GO:0044106 12 0.016
dna integrity checkpoint GO:0031570 81 0.016
translation GO:0006412 69 0.016
small molecule metabolic process GO:0044281 305 0.016
response to external biotic stimulus GO:0043207 293 0.015
posttranscriptional gene silencing GO:0016441 46 0.015
aging GO:0007568 143 0.015
regulation of transport GO:0051049 181 0.015
secretion by cell GO:0032940 101 0.015
intracellular signal transduction GO:0035556 300 0.015
defense response to bacterium GO:0042742 178 0.015
regulation of mapk cascade GO:0043408 92 0.015
chromosome organization GO:0051276 360 0.015
response to oxygen containing compound GO:1901700 200 0.015
covalent chromatin modification GO:0016569 106 0.014
cell proliferation GO:0008283 299 0.014
defense response to other organism GO:0098542 225 0.014
locomotory behavior GO:0007626 176 0.014
sensory organ morphogenesis GO:0090596 260 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
positive regulation of signal transduction GO:0009967 223 0.014
cell fate determination GO:0001709 91 0.014
neuroblast proliferation GO:0007405 74 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
camera type eye development GO:0043010 4 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
response to bacterium GO:0009617 198 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
protein modification process GO:0036211 438 0.013
enteroendocrine cell differentiation GO:0035883 1 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
regulation of immune response GO:0050776 118 0.013
regulation of cell cycle process GO:0010564 181 0.013
cellular catabolic process GO:0044248 372 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
macromolecular complex assembly GO:0065003 256 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
immune effector process GO:0002252 98 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
cell death GO:0008219 279 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
positive regulation of molecular function GO:0044093 136 0.012
Rat
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.012
phagocytosis GO:0006909 215 0.012
protein phosphorylation GO:0006468 169 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
response to endogenous stimulus GO:0009719 119 0.012
regulation of phosphorylation GO:0042325 147 0.012
chaeta development GO:0022416 97 0.012
negative regulation of cell death GO:0060548 81 0.012
regulation of catalytic activity GO:0050790 185 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
regulation of localization GO:0032879 275 0.012
single organism biosynthetic process GO:0044711 206 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
proteolysis GO:0006508 192 0.011
dendrite morphogenesis GO:0048813 199 0.011
stem cell differentiation GO:0048863 117 0.011
trna modification GO:0006400 2 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
ras protein signal transduction GO:0007265 88 0.011
compound eye development GO:0048749 307 0.011
heart process GO:0003015 37 0.011
cellular response to organic substance GO:0071310 132 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.011
response to abiotic stimulus GO:0009628 341 0.011
nitrogen compound transport GO:0071705 85 0.011
nuclear division GO:0000280 332 0.011
organic acid metabolic process GO:0006082 103 0.011
germ line stem cell maintenance GO:0030718 50 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.010
gastrulation with mouth forming first GO:0001703 36 0.010
eye antennal disc development GO:0035214 60 0.010
chromatin modification GO:0016568 147 0.010
gene silencing by rna GO:0031047 57 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
regulation of translation GO:0006417 56 0.010
epithelial cell differentiation GO:0030855 322 0.010
protein dna complex subunit organization GO:0071824 86 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
Rat
cellular nitrogen compound catabolic process GO:0044270 165 0.010
neural precursor cell proliferation GO:0061351 75 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.010
regulation of defense response GO:0031347 102 0.010
actin cytoskeleton organization GO:0030036 206 0.010
chromosome separation GO:0051304 42 0.010

MKP-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
disease of cellular proliferation DOID:14566 0 0.014
nervous system disease DOID:863 0 0.014