Drosophila melanogaster

149 known processes

Rab1 (Dmel_CG3320)

Rab-protein 1

(Aliases: Dm Rab1,rab1,Dmel\CG3320,RAB1a,dRab1,drab1,DmRab1,DRAB1,DRab1,AAF55873,CG3320,dar6)

Rab1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular catabolic process GO:0044248 372 0.721
Human
dendrite morphogenesis GO:0048813 199 0.696
cellular response to extracellular stimulus GO:0031668 64 0.660
Human
positive regulation of dendrite morphogenesis GO:0050775 9 0.454
regulation of dendrite morphogenesis GO:0048814 28 0.367
carbohydrate derivative catabolic process GO:1901136 118 0.346
Human
protein modification process GO:0036211 438 0.327
organic substance catabolic process GO:1901575 308 0.305
Human
modification dependent protein catabolic process GO:0019941 78 0.300
cellular protein modification process GO:0006464 438 0.280
regulation of localization GO:0032879 275 0.271
regulation of nervous system development GO:0051960 248 0.269
endocytosis GO:0006897 310 0.238
Human Rat Worm
regulation of catabolic process GO:0009894 170 0.230
Human
spermatogenesis GO:0007283 200 0.224
vesicle mediated transport GO:0016192 381 0.219
Human Rat Worm
modification dependent macromolecule catabolic process GO:0043632 79 0.216
cellular response to starvation GO:0009267 61 0.192
Human
positive regulation of nucleic acid templated transcription GO:1903508 266 0.187
axon guidance GO:0007411 233 0.187
cell motility GO:0048870 251 0.187
ubiquitin dependent protein catabolic process GO:0006511 78 0.173
male gamete generation GO:0048232 201 0.171
regulation of cell development GO:0060284 215 0.169
regulation of cell morphogenesis GO:0022604 163 0.158
single organism catabolic process GO:0044712 228 0.150
Human
molting cycle GO:0042303 56 0.147
Worm
axon development GO:0061564 297 0.141
positive regulation of multicellular organismal process GO:0051240 143 0.134
nucleoside triphosphate metabolic process GO:0009141 120 0.130
Human
immune system process GO:0002376 347 0.129
endocytic recycling GO:0032456 13 0.127
regulation of cell projection organization GO:0031344 92 0.120
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.120
nucleobase containing small molecule metabolic process GO:0055086 174 0.119
Human
positive regulation of cellular component organization GO:0051130 156 0.116
response to nutrient levels GO:0031667 114 0.116
Human
catabolic process GO:0009056 409 0.114
Human
maintenance of location GO:0051235 73 0.112
ribonucleotide metabolic process GO:0009259 145 0.111
Human
protein catabolic process GO:0030163 101 0.111
organic cyclic compound catabolic process GO:1901361 168 0.110
Human
phagosome acidification GO:0090383 1 0.109
regulation of cell differentiation GO:0045595 302 0.108
muscle structure development GO:0061061 224 0.106
epithelial cell differentiation GO:0030855 322 0.105
carbohydrate derivative metabolic process GO:1901135 217 0.104
Human
cellular response to nutrient levels GO:0031669 62 0.101
Human
positive regulation of cell differentiation GO:0045597 64 0.100
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.097
dendrite development GO:0016358 204 0.094
lipid storage GO:0019915 38 0.093
growth GO:0040007 359 0.087
cellular protein catabolic process GO:0044257 83 0.085
regulation of response to nutrient levels GO:0032107 18 0.085
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.084
regulation of dendrite development GO:0050773 37 0.084
nucleoside triphosphate catabolic process GO:0009143 108 0.084
Human
regulation of anatomical structure morphogenesis GO:0022603 242 0.082
macroautophagy GO:0016236 42 0.082
Human
ovarian follicle cell migration GO:0007297 121 0.080
response to abiotic stimulus GO:0009628 341 0.080
nucleoside metabolic process GO:0009116 127 0.077
Human
regulation of cellular catabolic process GO:0031329 157 0.076
Human
autophagy GO:0006914 108 0.076
Human
positive regulation of transport GO:0051050 92 0.075
cell migration GO:0016477 238 0.073
secretion GO:0046903 109 0.071
protein modification by small protein conjugation GO:0032446 79 0.064
aromatic compound catabolic process GO:0019439 166 0.060
Human
regulation of catalytic activity GO:0050790 185 0.060
establishment or maintenance of cell polarity GO:0007163 167 0.059
regulation of protein metabolic process GO:0051246 256 0.056
Human
axonogenesis GO:0007409 290 0.056
purine containing compound catabolic process GO:0072523 112 0.053
Human
purine nucleotide catabolic process GO:0006195 109 0.052
Human
positive regulation of molecular function GO:0044093 136 0.052
posttranscriptional regulation of gene expression GO:0010608 145 0.052
imaginal disc derived appendage development GO:0048737 399 0.052
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.051
Human
microtubule organizing center organization GO:0031023 168 0.050
regulation of autophagy GO:0010506 62 0.050
Human
purine ribonucleotide metabolic process GO:0009150 145 0.048
Human
purine nucleoside metabolic process GO:0042278 127 0.048
Human
synaptic transmission GO:0007268 288 0.048
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.048
Human
nucleobase containing compound catabolic process GO:0034655 165 0.045
Human
single organism nuclear import GO:1902593 51 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.045
ribonucleoside catabolic process GO:0042454 112 0.044
Human
proteolysis GO:0006508 192 0.043
positive regulation of cell development GO:0010720 61 0.043
organophosphate metabolic process GO:0019637 195 0.042
Human
actin cytoskeleton organization GO:0030036 206 0.041
regulation of hydrolase activity GO:0051336 97 0.041
regionalization GO:0003002 416 0.041
cellular response to chemical stimulus GO:0070887 199 0.041
regulation of neuron projection development GO:0010975 69 0.041
purine nucleoside triphosphate catabolic process GO:0009146 108 0.040
Human
regulation of growth GO:0040008 233 0.040
regulation of protein transport GO:0051223 57 0.040
oocyte construction GO:0007308 112 0.039
centrosome duplication GO:0051298 121 0.039
regulation of neuron differentiation GO:0045664 103 0.039
centrosome cycle GO:0007098 137 0.039
protein localization to organelle GO:0033365 82 0.039
intracellular protein transport GO:0006886 104 0.038
cellular protein localization GO:0034613 160 0.038
regulation of phosphate metabolic process GO:0019220 210 0.038
body morphogenesis GO:0010171 2 0.038
Worm
single organism intracellular transport GO:1902582 207 0.037
positive regulation of nervous system development GO:0051962 69 0.037
protein ubiquitination GO:0016567 70 0.037
regulation of molecular function GO:0065009 217 0.037
taxis GO:0042330 304 0.036
oocyte axis specification GO:0007309 108 0.036
vesicle organization GO:0016050 44 0.036
Human
carbohydrate derivative biosynthetic process GO:1901137 85 0.036
positive regulation of cellular protein metabolic process GO:0032270 118 0.036
positive regulation of protein metabolic process GO:0051247 128 0.036
Human
developmental growth GO:0048589 280 0.035
guanosine containing compound catabolic process GO:1901069 74 0.035
Human
nucleoside phosphate metabolic process GO:0006753 162 0.035
Human
organonitrogen compound metabolic process GO:1901564 318 0.034
Human
protein localization GO:0008104 284 0.034
nucleotide metabolic process GO:0009117 161 0.034
Human
purine ribonucleotide catabolic process GO:0009154 109 0.034
Human
enzyme linked receptor protein signaling pathway GO:0007167 179 0.034
localization of cell GO:0051674 257 0.034
phagocytosis GO:0006909 215 0.034
regulation of multicellular organismal development GO:2000026 414 0.034
glycosyl compound metabolic process GO:1901657 127 0.033
Human
photoreceptor cell differentiation GO:0046530 170 0.033
response to wounding GO:0009611 94 0.033
ribonucleotide catabolic process GO:0009261 109 0.033
Human
ribonucleoside metabolic process GO:0009119 127 0.033
Human
regulation of cell shape GO:0008360 113 0.032
cytoplasmic transport GO:0016482 130 0.032
Human Rat
purine nucleotide metabolic process GO:0006163 146 0.032
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.032
Human
macromolecule catabolic process GO:0009057 161 0.032
defense response GO:0006952 300 0.032
Human
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.032
regulation of organelle organization GO:0033043 196 0.031
Human
cellular response to external stimulus GO:0071496 66 0.031
Human
cellular macromolecule catabolic process GO:0044265 136 0.031
biological adhesion GO:0022610 138 0.031
regulation of cellular protein metabolic process GO:0032268 243 0.031
response to biotic stimulus GO:0009607 294 0.031
Human
regulation of cytoplasmic transport GO:1903649 47 0.030
embryonic development via the syncytial blastoderm GO:0001700 148 0.030
Fly
nucleoside phosphate catabolic process GO:1901292 110 0.030
Human
positive regulation of phosphorus metabolic process GO:0010562 139 0.030
positive regulation of neurogenesis GO:0050769 41 0.029
eye development GO:0001654 323 0.029
positive regulation of rna metabolic process GO:0051254 271 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.029
organonitrogen compound catabolic process GO:1901565 128 0.029
Human
purine nucleoside catabolic process GO:0006152 112 0.029
Human
larval development GO:0002164 104 0.028
Worm
cell growth GO:0016049 108 0.028
protein modification by small protein conjugation or removal GO:0070647 106 0.027
purine ribonucleoside metabolic process GO:0046128 127 0.027
Human
embryo development ending in birth or egg hatching GO:0009792 152 0.027
Worm Fly
cell maturation GO:0048469 144 0.027
hematopoietic or lymphoid organ development GO:0048534 57 0.027
response to bacterium GO:0009617 198 0.026
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
appendage morphogenesis GO:0035107 397 0.025
positive regulation of biosynthetic process GO:0009891 316 0.025
positive regulation of neuron differentiation GO:0045666 26 0.025
regulation of neurogenesis GO:0050767 158 0.025
establishment of localization in cell GO:0051649 402 0.025
positive regulation of cellular catabolic process GO:0031331 95 0.024
establishment of protein localization GO:0045184 163 0.024
centrosome organization GO:0051297 163 0.024
regulation of cell cycle GO:0051726 291 0.024
regulation of notch signaling pathway GO:0008593 100 0.024
single organism cellular localization GO:1902580 180 0.024
Human Mouse Rat
heterocycle catabolic process GO:0046700 166 0.024
Human
small gtpase mediated signal transduction GO:0007264 88 0.023
nucleoside catabolic process GO:0009164 112 0.023
Human
embryonic morphogenesis GO:0048598 206 0.023
Fly
lipid localization GO:0010876 54 0.023
small molecule metabolic process GO:0044281 305 0.023
Human
signal release GO:0023061 49 0.023
ribonucleoside triphosphate catabolic process GO:0009203 108 0.023
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
regulation of phosphatase activity GO:0010921 3 0.023
neuron projection guidance GO:0097485 241 0.023
gtp metabolic process GO:0046039 72 0.023
Human
cellular macromolecule localization GO:0070727 220 0.022
positive regulation of catalytic activity GO:0043085 118 0.022
regulation of hemocyte proliferation GO:0035206 37 0.022
chemotaxis GO:0006935 249 0.022
developmental maturation GO:0021700 172 0.022
cell proliferation GO:0008283 299 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
cytoplasm organization GO:0007028 64 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
ras protein signal transduction GO:0007265 88 0.021
negative regulation of cellular biosynthetic process GO:0031327 277 0.021
regulation of synaptic transmission GO:0050804 69 0.021
purine containing compound metabolic process GO:0072521 155 0.021
Human
purine ribonucleoside catabolic process GO:0046130 112 0.021
Human
intracellular transport GO:0046907 228 0.020
neuromuscular junction development GO:0007528 149 0.020
defense response to other organism GO:0098542 225 0.020
Human
ribose phosphate metabolic process GO:0019693 145 0.020
Human
negative regulation of cellular catabolic process GO:0031330 34 0.019
cell death GO:0008219 279 0.019
Worm
regulation of secretion by cell GO:1903530 39 0.019
border follicle cell migration GO:0007298 113 0.019
regulation of response to extracellular stimulus GO:0032104 18 0.019
Human
intracellular mrna localization GO:0008298 66 0.018
regulation of response to stress GO:0080134 200 0.018
Human
tissue morphogenesis GO:0048729 297 0.018
Fly
cellular response to organic substance GO:0071310 132 0.018
eye morphogenesis GO:0048592 260 0.018
organic substance transport GO:0071702 257 0.018
positive regulation of developmental process GO:0051094 143 0.018
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
Human
cellular nitrogen compound catabolic process GO:0044270 165 0.018
Human
regulation of protein localization GO:0032880 76 0.018
response to external biotic stimulus GO:0043207 293 0.018
Human
chemical homeostasis GO:0048878 92 0.018
positive regulation of catabolic process GO:0009896 105 0.018
muscle organ development GO:0007517 127 0.018
notch signaling pathway GO:0007219 120 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
Human
protein secretion GO:0009306 45 0.017
epithelial cell development GO:0002064 274 0.016
regulation of cellular localization GO:0060341 136 0.016
nucleocytoplasmic transport GO:0006913 72 0.016
protein targeting GO:0006605 64 0.016
cell division GO:0051301 248 0.016
cellular homeostasis GO:0019725 80 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.016
cortical cytoskeleton organization GO:0030865 29 0.016
proteasomal protein catabolic process GO:0010498 59 0.016
chromosome organization GO:0051276 360 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
positive regulation of organelle organization GO:0010638 65 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
embryonic pattern specification GO:0009880 174 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
negative regulation of gene expression GO:0010629 387 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
stem cell proliferation GO:0072089 88 0.015
negative regulation of autophagy GO:0010507 16 0.014
receptor mediated endocytosis GO:0006898 21 0.014
Worm
regulation of response to external stimulus GO:0032101 115 0.014
Human
death GO:0016265 284 0.014
Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
establishment of protein localization to organelle GO:0072594 62 0.014
protein transport GO:0015031 155 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.014
oocyte differentiation GO:0009994 145 0.014
positive regulation of developmental growth GO:0048639 62 0.014
positive regulation of gene expression GO:0010628 290 0.014
cell adhesion GO:0007155 136 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
compound eye morphogenesis GO:0001745 249 0.013
ameboidal type cell migration GO:0001667 151 0.013
negative regulation of phosphatase activity GO:0010923 3 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
regulation of cell death GO:0010941 173 0.013
regulation of intracellular transport GO:0032386 64 0.013
response to carbon dioxide GO:0010037 4 0.013
locomotory behavior GO:0007626 176 0.013
regulation of cell proliferation GO:0042127 163 0.013
positive regulation of cytoskeleton organization GO:0051495 21 0.012
aging GO:0007568 143 0.012
regulation of apoptotic process GO:0042981 130 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
positive regulation of secretion by cell GO:1903532 20 0.012
immune system development GO:0002520 57 0.011
meiotic nuclear division GO:0007126 151 0.011
protein k48 linked ubiquitination GO:0070936 3 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.011
ovarian follicle cell development GO:0030707 248 0.011
spermatid differentiation GO:0048515 114 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
positive regulation of intracellular protein transport GO:0090316 30 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
intracellular signal transduction GO:0035556 300 0.011
lysosome organization GO:0007040 4 0.011
cellularization GO:0007349 90 0.011
positive regulation of signaling GO:0023056 243 0.010
endomembrane system organization GO:0010256 119 0.010
Human
regulation of intracellular protein transport GO:0033157 46 0.010
instar larval development GO:0002168 55 0.010
regulation of transport GO:0051049 181 0.010
positive regulation of nfat protein import into nucleus GO:0051533 16 0.010
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.010
actin filament based process GO:0030029 220 0.010

Rab1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
muscle tissue disease DOID:66 0 0.016