Drosophila melanogaster

7 known processes

Prosbeta2 (Dmel_CG3329)

Proteasome beta2 subunit

(Aliases: DTS7,DTS-7,Dmel\CG3329,Dts7,CG3329,l(3)DTS7,anon-EST:fe1E6,beta2,Prosbeta,3329,anon-EST:fe1G6,beta2_dm)

Prosbeta2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 78 0.982
Yeast
modification dependent macromolecule catabolic process GO:0043632 79 0.969
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.953
Yeast
ubiquitin dependent protein catabolic process GO:0006511 78 0.939
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.888
proteasomal protein catabolic process GO:0010498 59 0.829
Yeast
protein catabolic process GO:0030163 101 0.806
Yeast
proteolysis GO:0006508 192 0.805
Yeast
cellular protein catabolic process GO:0044257 83 0.779
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.777
Yeast
cellular macromolecule catabolic process GO:0044265 136 0.723
Yeast
cellular catabolic process GO:0044248 372 0.618
Yeast
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.588
macromolecule catabolic process GO:0009057 161 0.518
Yeast
catabolic process GO:0009056 409 0.296
Yeast
organic substance catabolic process GO:1901575 308 0.237
Yeast
mitotic cell cycle phase transition GO:0044772 138 0.233
regulation of mitotic cell cycle phase transition GO:1901990 130 0.215
organelle assembly GO:0070925 198 0.183
regulation of mitotic cell cycle GO:0007346 190 0.179
cell cycle phase transition GO:0044770 140 0.167
macromolecular complex assembly GO:0065003 256 0.156
mitotic spindle elongation GO:0000022 81 0.148
multicellular organismal aging GO:0010259 140 0.147
Worm
body morphogenesis GO:0010171 2 0.136
determination of adult lifespan GO:0008340 137 0.128
Worm
negative regulation of mitotic cell cycle GO:0045930 109 0.116
larval development GO:0002164 104 0.112
Worm
g2 dna damage checkpoint GO:0031572 69 0.109
mitotic dna damage checkpoint GO:0044773 74 0.108
regulation of cell cycle process GO:0010564 181 0.105
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.097
embryo development ending in birth or egg hatching GO:0009792 152 0.093
Worm
dna templated transcription initiation GO:0006352 25 0.093
dna repair GO:0006281 54 0.092
lateral inhibition GO:0046331 206 0.089
mitotic g2 m transition checkpoint GO:0044818 70 0.088
negative regulation of cell cycle process GO:0010948 109 0.087
negative regulation of cell cycle GO:0045786 116 0.086
protein complex assembly GO:0006461 200 0.086
regulation of proteolysis GO:0030162 87 0.083
regulation of organelle organization GO:0033043 196 0.079
nuclear division GO:0000280 332 0.076
response to oxidative stress GO:0006979 86 0.075
ribonucleoside catabolic process GO:0042454 112 0.070
dna damage checkpoint GO:0000077 78 0.066
mitotic spindle organization GO:0007052 220 0.066
regionalization GO:0003002 416 0.055
organelle fission GO:0048285 340 0.051
cellular nitrogen compound catabolic process GO:0044270 165 0.050
ribose phosphate metabolic process GO:0019693 145 0.050
multi multicellular organism process GO:0044706 123 0.049
regulation of cell cycle GO:0051726 291 0.049
mitotic g2 dna damage checkpoint GO:0007095 69 0.048
camera type eye development GO:0043010 4 0.048
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.047
carbohydrate derivative catabolic process GO:1901136 118 0.046
eye photoreceptor cell differentiation GO:0001754 145 0.043
negative regulation of developmental process GO:0051093 201 0.043
negative regulation of cell cycle phase transition GO:1901988 103 0.042
morphogenesis of an epithelium GO:0002009 276 0.041
cellular protein modification process GO:0006464 438 0.039
regulation of cellular protein metabolic process GO:0032268 243 0.039
cell cycle checkpoint GO:0000075 95 0.039
cellular macromolecular complex assembly GO:0034622 153 0.038
regulation of endopeptidase activity GO:0052548 36 0.037
multi organism reproductive behavior GO:0044705 121 0.036
protein complex biogenesis GO:0070271 201 0.036
protein dna complex subunit organization GO:0071824 86 0.036
synaptic transmission GO:0007268 288 0.036
protein deneddylation GO:0000338 8 0.034
stem cell differentiation GO:0048863 117 0.034
regulation of notch signaling pathway GO:0008593 100 0.034
cellular response to oxygen containing compound GO:1901701 79 0.033
protein modification by small protein conjugation or removal GO:0070647 106 0.032
positive regulation of proteolysis GO:0045862 52 0.030
regulation of molecular function GO:0065009 217 0.029
mitotic nuclear division GO:0007067 213 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
dna integrity checkpoint GO:0031570 81 0.028
purine nucleoside catabolic process GO:0006152 112 0.028
nucleoside phosphate catabolic process GO:1901292 110 0.028
positive regulation of response to stimulus GO:0048584 323 0.027
heterocycle catabolic process GO:0046700 166 0.027
negative regulation of transcription dna templated GO:0045892 237 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.026
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.026
multicellular organismal reproductive behavior GO:0033057 110 0.026
negative regulation of purine nucleotide catabolic process GO:0033122 1 0.026
regulation of cell cycle phase transition GO:1901987 130 0.026
oviposition GO:0018991 19 0.025
organonitrogen compound metabolic process GO:1901564 318 0.025
ribonucleoside triphosphate catabolic process GO:0009203 108 0.025
cellular component assembly involved in morphogenesis GO:0010927 151 0.025
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.024
mitotic dna integrity checkpoint GO:0044774 75 0.024
cell cell signaling involved in cell fate commitment GO:0045168 210 0.024
regulation of striated muscle contraction GO:0006942 2 0.023
positive regulation of peptidase activity GO:0010952 29 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.022
positive regulation of transcription dna templated GO:0045893 266 0.022
regulation of chromosome organization GO:0033044 64 0.022
small molecule metabolic process GO:0044281 305 0.022
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.020
regulation of vesicle mediated transport GO:0060627 59 0.020
peptidyl amino acid modification GO:0018193 105 0.019
positive regulation of cellular protein metabolic process GO:0032270 118 0.019
positive regulation of nucleic acid templated transcription GO:1903508 266 0.019
actin cytoskeleton organization GO:0030036 206 0.019
positive regulation of cellular component organization GO:0051130 156 0.019
mitotic cell cycle checkpoint GO:0007093 88 0.019
negative regulation of phosphatase activity GO:0010923 3 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.019
notch receptor processing GO:0007220 13 0.018
nucleoside catabolic process GO:0009164 112 0.018
regulation of catalytic activity GO:0050790 185 0.018
chemotaxis GO:0006935 249 0.018
protein modification process GO:0036211 438 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
molting cycle GO:0042303 56 0.018
cell division GO:0051301 248 0.018
reproductive behavior GO:0019098 122 0.018
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.017
vesicle mediated transport GO:0016192 381 0.017
endocytosis GO:0006897 310 0.017
cell motility GO:0048870 251 0.017
regulation of cellular protein catabolic process GO:1903362 44 0.017
dna templated transcription elongation GO:0006354 18 0.017
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.016
proteasome assembly GO:0043248 2 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
spindle organization GO:0007051 253 0.016
intracellular transport GO:0046907 228 0.016
dna metabolic process GO:0006259 227 0.016
single organism catabolic process GO:0044712 228 0.015
response to other organism GO:0051707 293 0.015
regulation of phosphatase activity GO:0010921 3 0.015
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
negative regulation of response to stimulus GO:0048585 258 0.014
chromosome segregation GO:0007059 157 0.014
aromatic compound catabolic process GO:0019439 166 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
epithelial cell differentiation GO:0030855 322 0.014
protein modification by small protein conjugation GO:0032446 79 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
phospholipid transport GO:0015914 2 0.014
cellular response to nutrient GO:0031670 1 0.013
cellular protein complex assembly GO:0043623 71 0.013
positive regulation of catabolic process GO:0009896 105 0.013
response to organic substance GO:0010033 284 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
spindle assembly GO:0051225 80 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
response to external biotic stimulus GO:0043207 293 0.012
regulation of gtpase activity GO:0043087 44 0.012
chromatin organization GO:0006325 207 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
meiotic cell cycle GO:0051321 171 0.012
negative regulation of transcription factor import into nucleus GO:0042992 4 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
digestive tract morphogenesis GO:0048546 127 0.011
regulation of response to stress GO:0080134 200 0.011
positive regulation of endopeptidase activity GO:0010950 26 0.011
neuron projection guidance GO:0097485 241 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
regulation of atp catabolic process GO:1903289 4 0.011
neurological system process GO:0050877 358 0.011
cell migration GO:0016477 238 0.011
spindle assembly involved in mitosis GO:0090307 50 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
regulation of cellular catabolic process GO:0031329 157 0.010
regulation of cellular response to stress GO:0080135 89 0.010
organophosphate catabolic process GO:0046434 112 0.010
amine metabolic process GO:0009308 12 0.010
regulation of hemocyte proliferation GO:0035206 37 0.010
nucleoside metabolic process GO:0009116 127 0.010
peptidyl serine phosphorylation GO:0018105 7 0.010
positive regulation of catalytic activity GO:0043085 118 0.010

Prosbeta2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.021
benign neoplasm DOID:0060072 0 0.021