Drosophila melanogaster

0 known processes

ClC-a (Dmel_CG31116)

Chloride channel-a

(Aliases: Dmel\CG31116,CG6942,DmClC-a,DmClCa,FBgn0037951,CG31116,DmClC-2,CG14726)

ClC-a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic appendage morphogenesis GO:0035120 385 0.123
imaginal disc derived appendage development GO:0048737 399 0.105
imaginal disc derived appendage morphogenesis GO:0035114 395 0.094
regulation of cell shape GO:0008360 113 0.084
appendage morphogenesis GO:0035107 397 0.072
sensory organ morphogenesis GO:0090596 260 0.063
homeostatic process GO:0042592 199 0.062
single organism behavior GO:0044708 391 0.060
eye development GO:0001654 323 0.058
appendage development GO:0048736 401 0.058
leg disc development GO:0035218 92 0.057
morphogenesis of an epithelium GO:0002009 276 0.056
regulation of anatomical structure morphogenesis GO:0022603 242 0.054
response to radiation GO:0009314 155 0.053
regionalization GO:0003002 416 0.053
regulation of anatomical structure size GO:0090066 163 0.050
eye morphogenesis GO:0048592 260 0.046
organonitrogen compound metabolic process GO:1901564 318 0.046
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.045
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.045
protein localization GO:0008104 284 0.043
imaginal disc derived wing morphogenesis GO:0007476 337 0.043
cellular protein modification process GO:0006464 438 0.042
organophosphate metabolic process GO:0019637 195 0.042
cellular amide metabolic process GO:0043603 80 0.041
protein complex assembly GO:0006461 200 0.040
transcription from rna polymerase ii promoter GO:0006366 368 0.040
intracellular signal transduction GO:0035556 300 0.040
negative regulation of signaling GO:0023057 219 0.039
protein modification process GO:0036211 438 0.038
negative regulation of rna metabolic process GO:0051253 251 0.038
negative regulation of rna biosynthetic process GO:1902679 240 0.038
catabolic process GO:0009056 409 0.035
wing disc morphogenesis GO:0007472 344 0.035
negative regulation of transcription dna templated GO:0045892 237 0.035
small molecule metabolic process GO:0044281 305 0.035
cellular macromolecule localization GO:0070727 220 0.035
regulation of nervous system development GO:0051960 248 0.034
carboxylic acid metabolic process GO:0019752 92 0.034
organic acid metabolic process GO:0006082 103 0.034
compound eye morphogenesis GO:0001745 249 0.033
tissue morphogenesis GO:0048729 297 0.033
cell cell signaling involved in cell fate commitment GO:0045168 210 0.033
dna metabolic process GO:0006259 227 0.033
establishment of localization in cell GO:0051649 402 0.033
compound eye development GO:0048749 307 0.033
growth GO:0040007 359 0.033
response to abiotic stimulus GO:0009628 341 0.032
Rat
oxoacid metabolic process GO:0043436 103 0.032
response to light stimulus GO:0009416 124 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.031
regulation of transport GO:0051049 181 0.031
Rat
cellular response to dna damage stimulus GO:0006974 223 0.031
regulation of cell death GO:0010941 173 0.031
cellular homeostasis GO:0019725 80 0.030
cellular catabolic process GO:0044248 372 0.030
negative regulation of cellular biosynthetic process GO:0031327 277 0.030
regulation of organelle organization GO:0033043 196 0.030
negative regulation of cellular metabolic process GO:0031324 382 0.030
positive regulation of signaling GO:0023056 243 0.030
developmental growth GO:0048589 280 0.029
negative regulation of biosynthetic process GO:0009890 277 0.029
cell division GO:0051301 248 0.029
death GO:0016265 284 0.029
chemosensory behavior GO:0007635 106 0.029
single organism catabolic process GO:0044712 228 0.029
negative regulation of cell communication GO:0010648 223 0.029
negative regulation of gene expression GO:0010629 387 0.028
regulation of cell cycle GO:0051726 291 0.028
positive regulation of cell communication GO:0010647 250 0.027
organic substance transport GO:0071702 257 0.027
regulation of response to stress GO:0080134 200 0.027
cellular amino acid metabolic process GO:0006520 61 0.026
negative regulation of response to stimulus GO:0048585 258 0.026
axon guidance GO:0007411 233 0.025
lateral inhibition GO:0046331 206 0.025
chromosome organization GO:0051276 360 0.025
ras protein signal transduction GO:0007265 88 0.025
neurological system process GO:0050877 358 0.024
regulation of cell morphogenesis GO:0022604 163 0.024
small gtpase mediated signal transduction GO:0007264 88 0.024
cell death GO:0008219 279 0.024
forebrain development GO:0030900 2 0.024
establishment of protein localization GO:0045184 163 0.024
nuclear division GO:0000280 332 0.024
cell growth GO:0016049 108 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.023
negative regulation of signal transduction GO:0009968 206 0.023
monocarboxylic acid transport GO:0015718 3 0.023
organic substance catabolic process GO:1901575 308 0.023
developmental maturation GO:0021700 172 0.023
protein transport GO:0015031 155 0.023
cellular amine metabolic process GO:0044106 12 0.022
vesicle mediated transport GO:0016192 381 0.022
response to organophosphorus GO:0046683 2 0.022
multi organism behavior GO:0051705 175 0.022
secretion by cell GO:0032940 101 0.022
gland development GO:0048732 191 0.022
peptide metabolic process GO:0006518 80 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
segmentation GO:0035282 207 0.021
locomotory behavior GO:0007626 176 0.021
anion transport GO:0006820 41 0.021
Rat
cellular protein localization GO:0034613 160 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
heterocycle catabolic process GO:0046700 166 0.021
organelle fission GO:0048285 340 0.021
spindle organization GO:0007051 253 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
glycosyl compound metabolic process GO:1901657 127 0.021
ribose phosphate metabolic process GO:0019693 145 0.021
nucleoside triphosphate metabolic process GO:0009141 120 0.020
immune system process GO:0002376 347 0.020
regulation of cell differentiation GO:0045595 302 0.020
positive regulation of growth GO:0045927 75 0.020
aromatic compound catabolic process GO:0019439 166 0.020
defense response GO:0006952 300 0.020
exocrine system development GO:0035272 162 0.020
body morphogenesis GO:0010171 2 0.020
programmed cell death GO:0012501 257 0.020
secretion GO:0046903 109 0.020
Rat
pigmentation GO:0043473 75 0.020
embryonic pattern specification GO:0009880 174 0.019
chemotaxis GO:0006935 249 0.019
regulation of response to external stimulus GO:0032101 115 0.019
phagocytosis GO:0006909 215 0.019
regulation of gene expression epigenetic GO:0040029 128 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
regulation of growth GO:0040008 233 0.018
adult behavior GO:0030534 137 0.018
olfactory learning GO:0008355 56 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
response to organic substance GO:0010033 284 0.018
positive regulation of response to stimulus GO:0048584 323 0.018
response to external biotic stimulus GO:0043207 293 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
cation transport GO:0006812 110 0.018
tube development GO:0035295 244 0.017
Rat
salivary gland morphogenesis GO:0007435 145 0.017
negative regulation of mitotic cell cycle GO:0045930 109 0.017
response to lipopolysaccharide GO:0032496 4 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
ribonucleotide metabolic process GO:0009259 145 0.017
purine containing compound metabolic process GO:0072521 155 0.017
gland morphogenesis GO:0022612 145 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
axon development GO:0061564 297 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
cell proliferation GO:0008283 299 0.016
salivary gland development GO:0007431 162 0.016
endomembrane system organization GO:0010256 119 0.016
tube morphogenesis GO:0035239 191 0.016
oxidation reduction process GO:0055114 123 0.016
embryonic morphogenesis GO:0048598 206 0.016
regulation of localization GO:0032879 275 0.016
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
chromatin organization GO:0006325 207 0.015
cell adhesion GO:0007155 136 0.015
telencephalon development GO:0021537 2 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.015
ion transport GO:0006811 145 0.015
Rat
central nervous system development GO:0007417 201 0.015
transmembrane transport GO:0055085 139 0.015
Rat
dorsal ventral pattern formation GO:0009953 133 0.015
phosphorylation GO:0016310 294 0.015
neuron projection guidance GO:0097485 241 0.015
cellular response to organic substance GO:0071310 132 0.015
blastoderm segmentation GO:0007350 159 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
regulation of neurogenesis GO:0050767 158 0.015
response to other organism GO:0051707 293 0.015
oocyte differentiation GO:0009994 145 0.015
chemical homeostasis GO:0048878 92 0.015
regulation of catalytic activity GO:0050790 185 0.015
embryonic axis specification GO:0000578 107 0.015
camera type eye development GO:0043010 4 0.015
kidney development GO:0001822 3 0.015
Rat
imaginal disc pattern formation GO:0007447 91 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
endocytosis GO:0006897 310 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
meiotic nuclear division GO:0007126 151 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
positive regulation of catabolic process GO:0009896 105 0.014
regulation of apoptotic process GO:0042981 130 0.014
regulation of phosphorylation GO:0042325 147 0.014
response to bacterium GO:0009617 198 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
covalent chromatin modification GO:0016569 106 0.014
rhythmic process GO:0048511 106 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
positive regulation of signal transduction GO:0009967 223 0.014
taxis GO:0042330 304 0.014
organophosphate catabolic process GO:0046434 112 0.014
imaginal disc derived leg morphogenesis GO:0007480 80 0.014
gliogenesis GO:0042063 80 0.014
sterol homeostasis GO:0055092 4 0.014
multicellular organismal reproductive behavior GO:0033057 110 0.014
synapse organization GO:0050808 196 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
macromolecular complex assembly GO:0065003 256 0.014
regulation of cell development GO:0060284 215 0.014
epithelial tube morphogenesis GO:0060562 88 0.013
regulation of synaptic transmission GO:0050804 69 0.013
neural precursor cell proliferation GO:0061351 75 0.013
inorganic ion transmembrane transport GO:0098660 73 0.013
Rat
regulation of developmental growth GO:0048638 174 0.013
leg disc morphogenesis GO:0007478 80 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
nucleoside metabolic process GO:0009116 127 0.013
response to monosaccharide GO:0034284 4 0.013
regulation of protein metabolic process GO:0051246 256 0.013
cellular response to carbohydrate stimulus GO:0071322 4 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
biological adhesion GO:0022610 138 0.013
cellular ion homeostasis GO:0006873 39 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
regulation of cellular response to stress GO:0080135 89 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
nucleotide metabolic process GO:0009117 161 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
mapk cascade GO:0000165 107 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
epithelial cell differentiation GO:0030855 322 0.013
response to oxygen containing compound GO:1901700 200 0.013
Rat
protein heterooligomerization GO:0051291 4 0.013
detection of chemical stimulus GO:0009593 93 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
anion transmembrane transport GO:0098656 26 0.012
Rat
apoptotic process GO:0006915 159 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
eggshell formation GO:0030703 105 0.012
associative learning GO:0008306 65 0.012
sulfur compound metabolic process GO:0006790 59 0.012
carbohydrate metabolic process GO:0005975 82 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
vitamin metabolic process GO:0006766 2 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
positive regulation of nucleotide metabolic process GO:0045981 55 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
positive regulation of cell migration GO:0030335 2 0.012
negative regulation of cell cycle GO:0045786 116 0.012
nitrogen compound transport GO:0071705 85 0.012
regulation of catabolic process GO:0009894 170 0.012
response to nutrient levels GO:0031667 114 0.012
regulation of cell cycle process GO:0010564 181 0.012
axis specification GO:0009798 167 0.012
single organism biosynthetic process GO:0044711 206 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
positive regulation of cell motility GO:2000147 3 0.011
cognition GO:0050890 141 0.011
open tracheal system development GO:0007424 204 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
regulation of cellular component size GO:0032535 98 0.011
neuroblast proliferation GO:0007405 74 0.011
cellular response to endogenous stimulus GO:0071495 80 0.011
circulatory system development GO:0072359 82 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
sensory perception of pain GO:0019233 4 0.011
spermatogenesis GO:0007283 200 0.011
synapse assembly GO:0007416 143 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
brain development GO:0007420 120 0.011
positive regulation of developmental process GO:0051094 143 0.011
cholesterol homeostasis GO:0042632 3 0.011
response to copper ion GO:0046688 4 0.011
positive regulation of cell development GO:0010720 61 0.011
gene silencing GO:0016458 138 0.011
intracellular mrna localization GO:0008298 66 0.011
single organism intracellular transport GO:1902582 207 0.011
anion homeostasis GO:0055081 3 0.011
regulation of cell projection organization GO:0031344 92 0.011
glutathione metabolic process GO:0006749 37 0.011
cellular ketone metabolic process GO:0042180 24 0.011
rho protein signal transduction GO:0007266 14 0.011
regulation of cellular localization GO:0060341 136 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
chromatin silencing GO:0006342 76 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
carboxylic acid transport GO:0046942 18 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
chorion containing eggshell formation GO:0007304 105 0.011
chromosome segregation GO:0007059 157 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010
response to organic cyclic compound GO:0014070 89 0.010
regulation of neuron differentiation GO:0045664 103 0.010
regulation of cell growth GO:0001558 43 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
muscle organ development GO:0007517 127 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
nucleoside catabolic process GO:0009164 112 0.010
amine metabolic process GO:0009308 12 0.010
regulation of molecular function GO:0065009 217 0.010
epithelial cell development GO:0002064 274 0.010
localization of cell GO:0051674 257 0.010
mitotic nuclear division GO:0007067 213 0.010
detection of stimulus GO:0051606 156 0.010
morphogenesis of a polarized epithelium GO:0001738 93 0.010
cell maturation GO:0048469 144 0.010

ClC-a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.088
Human
disease of metabolism DOID:0014667 0 0.039
inherited metabolic disorder DOID:655 0 0.022
cardiovascular system disease DOID:1287 0 0.017
musculoskeletal system disease DOID:17 0 0.017
nervous system disease DOID:863 0 0.016
Human