Drosophila melanogaster

14 known processes

Brd8 (Dmel_CG14514)

CG14514 gene product from transcript CG14514-RA

(Aliases: dBrd8,CG14514,Dmel\CG14514)

Brd8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of rna metabolic process GO:0051254 271 0.227
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.218
positive regulation of gene expression GO:0010628 290 0.180
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.163
negative regulation of gene expression GO:0010629 387 0.150
positive regulation of nucleic acid templated transcription GO:1903508 266 0.150
positive regulation of rna biosynthetic process GO:1902680 266 0.149
negative regulation of rna metabolic process GO:0051253 251 0.129
cell division GO:0051301 248 0.121
positive regulation of macromolecule metabolic process GO:0010604 405 0.121
organelle fission GO:0048285 340 0.117
transcription from rna polymerase ii promoter GO:0006366 368 0.111
macromolecular complex assembly GO:0065003 256 0.099
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.090
negative regulation of nucleic acid templated transcription GO:1903507 240 0.089
mrna metabolic process GO:0016071 124 0.080
body morphogenesis GO:0010171 2 0.075
peptidyl lysine modification GO:0018205 57 0.067
Human
mitotic spindle organization GO:0007052 220 0.067
mrna processing GO:0006397 104 0.067
positive regulation of biosynthetic process GO:0009891 316 0.064
cell migration GO:0016477 238 0.063
nuclear division GO:0000280 332 0.063
positive regulation of transcription dna templated GO:0045893 266 0.063
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.062
imaginal disc derived wing morphogenesis GO:0007476 337 0.060
catabolic process GO:0009056 409 0.059
gene silencing GO:0016458 138 0.058
post embryonic appendage morphogenesis GO:0035120 385 0.057
intracellular transport GO:0046907 228 0.055
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.054
cellularization GO:0007349 90 0.049
cytoplasmic transport GO:0016482 130 0.048
organonitrogen compound metabolic process GO:1901564 318 0.048
small molecule metabolic process GO:0044281 305 0.048
imaginal disc derived appendage development GO:0048737 399 0.046
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.046
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.045
regulation of mrna splicing via spliceosome GO:0048024 64 0.044
developmental growth GO:0048589 280 0.043
cell motility GO:0048870 251 0.043
wing disc morphogenesis GO:0007472 344 0.042
imaginal disc derived appendage morphogenesis GO:0035114 395 0.041
protein modification process GO:0036211 438 0.041
Human
regulation of cellular component biogenesis GO:0044087 201 0.039
spindle organization GO:0007051 253 0.039
appendage development GO:0048736 401 0.039
phosphorylation GO:0016310 294 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.038
negative regulation of cellular biosynthetic process GO:0031327 277 0.038
mitotic nuclear division GO:0007067 213 0.038
negative regulation of transcription dna templated GO:0045892 237 0.037
protein complex assembly GO:0006461 200 0.037
histone modification GO:0016570 106 0.036
Human
negative regulation of biosynthetic process GO:0009890 277 0.036
rna localization GO:0006403 115 0.035
cellular catabolic process GO:0044248 372 0.035
regulation of rna splicing GO:0043484 69 0.034
positive regulation of cellular biosynthetic process GO:0031328 316 0.034
regulation of organelle organization GO:0033043 196 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.032
negative regulation of rna biosynthetic process GO:1902679 240 0.032
cellular amine metabolic process GO:0044106 12 0.032
single organism behavior GO:0044708 391 0.031
cellular macromolecule catabolic process GO:0044265 136 0.031
regulation of gene silencing GO:0060968 63 0.031
regulation of cell cycle GO:0051726 291 0.030
cell proliferation GO:0008283 299 0.030
growth GO:0040007 359 0.030
positive regulation of cellular component organization GO:0051130 156 0.030
organic substance transport GO:0071702 257 0.030
regionalization GO:0003002 416 0.029
organic acid metabolic process GO:0006082 103 0.029
protein modification by small protein conjugation GO:0032446 79 0.029
regulation of cellular amine metabolic process GO:0033238 3 0.028
protein complex biogenesis GO:0070271 201 0.028
protein acetylation GO:0006473 39 0.028
Human
response to abiotic stimulus GO:0009628 341 0.028
protein acylation GO:0043543 42 0.027
Human
alternative mrna splicing via spliceosome GO:0000380 60 0.027
pole cell formation GO:0007279 19 0.027
regulation of cell cycle process GO:0010564 181 0.027
regulation of catabolic process GO:0009894 170 0.026
regulation of mrna processing GO:0050684 71 0.025
appendage morphogenesis GO:0035107 397 0.025
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.024
localization of cell GO:0051674 257 0.024
epithelial cell development GO:0002064 274 0.024
nucleocytoplasmic transport GO:0006913 72 0.024
tube development GO:0035295 244 0.024
covalent chromatin modification GO:0016569 106 0.024
Human
egg activation GO:0007343 9 0.023
organic substance catabolic process GO:1901575 308 0.023
establishment of protein localization GO:0045184 163 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.023
vesicle mediated transport GO:0016192 381 0.023
neurological system process GO:0050877 358 0.022
positive regulation of developmental process GO:0051094 143 0.022
oxoacid metabolic process GO:0043436 103 0.021
tube morphogenesis GO:0035239 191 0.021
camera type eye morphogenesis GO:0048593 2 0.020
positive regulation of protein metabolic process GO:0051247 128 0.019
positive regulation of cellular protein metabolic process GO:0032270 118 0.019
regulation of cell cycle phase transition GO:1901987 130 0.019
chromosome organization GO:0051276 360 0.019
Human
endocytosis GO:0006897 310 0.019
regulation of meiosis GO:0040020 3 0.019
mrna splicing via spliceosome GO:0000398 73 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
nitrogen compound transport GO:0071705 85 0.018
compound eye morphogenesis GO:0001745 249 0.018
amine metabolic process GO:0009308 12 0.018
dna conformation change GO:0071103 105 0.018
axis specification GO:0009798 167 0.017
cellular protein complex assembly GO:0043623 71 0.017
regulation of cell division GO:0051302 72 0.017
regulation of catalytic activity GO:0050790 185 0.017
pole cell development GO:0007277 26 0.017
rna splicing GO:0008380 83 0.017
internal protein amino acid acetylation GO:0006475 38 0.017
Human
cellular response to dna damage stimulus GO:0006974 223 0.016
establishment of rna localization GO:0051236 47 0.016
reproductive structure development GO:0048608 74 0.016
organophosphate metabolic process GO:0019637 195 0.016
segmentation GO:0035282 207 0.016
cellular protein modification process GO:0006464 438 0.016
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
macromolecule catabolic process GO:0009057 161 0.016
regulation of growth GO:0040008 233 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
regulation of response to stress GO:0080134 200 0.015
epithelial cell differentiation GO:0030855 322 0.015
regulation of chromatin organization GO:1902275 32 0.015
chromatin modification GO:0016568 147 0.015
Human
positive regulation of organelle organization GO:0010638 65 0.015
single organism cellular localization GO:1902580 180 0.015
positive regulation of signal transduction GO:0009967 223 0.015
single organism catabolic process GO:0044712 228 0.015
positive regulation of cell communication GO:0010647 250 0.015
modification dependent protein catabolic process GO:0019941 78 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
negative regulation of gene expression epigenetic GO:0045814 77 0.014
heart development GO:0007507 82 0.014
cell cycle phase transition GO:0044770 140 0.014
regulation of molecular function GO:0065009 217 0.014
regulation of cellular localization GO:0060341 136 0.014
regulation of nuclear division GO:0051783 58 0.014
regulation of mapk cascade GO:0043408 92 0.014
retina development in camera type eye GO:0060041 4 0.014
response to biotic stimulus GO:0009607 294 0.014
cellular protein catabolic process GO:0044257 83 0.014
positive regulation of signaling GO:0023056 243 0.014
cellular ketone metabolic process GO:0042180 24 0.013
nucleobase containing compound transport GO:0015931 56 0.013
locomotory behavior GO:0007626 176 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
establishment of localization in cell GO:0051649 402 0.013
circulatory system development GO:0072359 82 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
regulation of neurogenesis GO:0050767 158 0.013
protein transport GO:0015031 155 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
proteolysis GO:0006508 192 0.013
axon development GO:0061564 297 0.013
meiotic nuclear division GO:0007126 151 0.013
connective tissue development GO:0061448 3 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
regulation of cytoplasmic transport GO:1903649 47 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
phagocytosis GO:0006909 215 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
chromatin organization GO:0006325 207 0.012
Human
photoreceptor cell differentiation GO:0046530 170 0.012
rna splicing via transesterification reactions GO:0000375 73 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
forebrain development GO:0030900 2 0.012
rna transport GO:0050658 46 0.012
head development GO:0060322 135 0.012
nuclear transport GO:0051169 72 0.012
regulation of developmental growth GO:0048638 174 0.012
response to heat GO:0009408 63 0.011
regulation of localization GO:0032879 275 0.011
response to organic substance GO:0010033 284 0.011
anterior posterior pattern specification GO:0009952 136 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
intracellular signal transduction GO:0035556 300 0.011
positive regulation of molecular function GO:0044093 136 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
tissue morphogenesis GO:0048729 297 0.011
imaginal disc pattern formation GO:0007447 91 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.011
spindle assembly GO:0051225 80 0.011
ras protein signal transduction GO:0007265 88 0.011
mitotic sister chromatid separation GO:0051306 30 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
regulation of protein metabolic process GO:0051246 256 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
response to other organism GO:0051707 293 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
brain development GO:0007420 120 0.011
fertilization GO:0009566 26 0.011
regulation of cell differentiation GO:0045595 302 0.011
embryonic axis specification GO:0000578 107 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
cellular response to organic substance GO:0071310 132 0.011
dna methylation GO:0006306 4 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
meiotic cell cycle GO:0051321 171 0.010
stem cell differentiation GO:0048863 117 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
telencephalon development GO:0021537 2 0.010
protein catabolic process GO:0030163 101 0.010
hindbrain development GO:0030902 2 0.010

Brd8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
disease of cellular proliferation DOID:14566 0 0.016
nervous system disease DOID:863 0 0.015
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.011