Drosophila melanogaster

30 known processes

Madm (Dmel_CG1098)

MLF1-adaptor molecule

(Aliases: Dmel\CG1098,anon-WO0118547.406,MADM,dMADM,CG1098,BcDNA:LD28657)

Madm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 381 0.184
Human
organonitrogen compound metabolic process GO:1901564 318 0.173
small molecule metabolic process GO:0044281 305 0.121
homeostatic process GO:0042592 199 0.100
cell proliferation GO:0008283 299 0.095
dna metabolic process GO:0006259 227 0.093
multicellular organismal aging GO:0010259 140 0.080
regulation of developmental growth GO:0048638 174 0.079
cellular response to dna damage stimulus GO:0006974 223 0.077
organic cyclic compound catabolic process GO:1901361 168 0.077
endocytosis GO:0006897 310 0.074
defense response to bacterium GO:0042742 178 0.071
chemical homeostasis GO:0048878 92 0.069
centrosome organization GO:0051297 163 0.068
catabolic process GO:0009056 409 0.064
cellular catabolic process GO:0044248 372 0.062
axonogenesis GO:0007409 290 0.062
Fly
nucleosome organization GO:0034728 59 0.061
ribonucleoside metabolic process GO:0009119 127 0.059
heterocycle catabolic process GO:0046700 166 0.059
regulation of response to stress GO:0080134 200 0.058
growth GO:0040007 359 0.058
chromatin organization GO:0006325 207 0.057
purine nucleoside catabolic process GO:0006152 112 0.057
nucleotide metabolic process GO:0009117 161 0.054
ribonucleoside triphosphate catabolic process GO:0009203 108 0.054
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.054
negative regulation of developmental process GO:0051093 201 0.052
ribonucleoside catabolic process GO:0042454 112 0.052
immune system process GO:0002376 347 0.051
purine containing compound metabolic process GO:0072521 155 0.049
nucleobase containing compound catabolic process GO:0034655 165 0.049
organophosphate metabolic process GO:0019637 195 0.049
developmental growth GO:0048589 280 0.049
response to bacterium GO:0009617 198 0.048
nucleoside catabolic process GO:0009164 112 0.048
negative regulation of response to stimulus GO:0048585 258 0.048
negative regulation of cellular metabolic process GO:0031324 382 0.047
dna packaging GO:0006323 91 0.046
regulation of growth GO:0040008 233 0.045
protein complex biogenesis GO:0070271 201 0.045
defense response to other organism GO:0098542 225 0.045
spermatogenesis GO:0007283 200 0.044
intracellular signal transduction GO:0035556 300 0.044
neurological system process GO:0050877 358 0.043
protein phosphorylation GO:0006468 169 0.043
Fly
single organism catabolic process GO:0044712 228 0.042
nucleoside phosphate metabolic process GO:0006753 162 0.040
transcription from rna polymerase ii promoter GO:0006366 368 0.038
purine ribonucleoside catabolic process GO:0046130 112 0.038
cellular nitrogen compound catabolic process GO:0044270 165 0.037
chromosome organization GO:0051276 360 0.037
cellular amine metabolic process GO:0044106 12 0.036
ribonucleotide catabolic process GO:0009261 109 0.036
purine ribonucleotide metabolic process GO:0009150 145 0.036
purine ribonucleoside metabolic process GO:0046128 127 0.036
centrosome duplication GO:0051298 121 0.036
response to oxygen containing compound GO:1901700 200 0.036
response to organic substance GO:0010033 284 0.036
positive regulation of signaling GO:0023056 243 0.035
Fly
regulation of intracellular signal transduction GO:1902531 236 0.035
negative regulation of multicellular organismal process GO:0051241 142 0.034
meiotic chromosome segregation GO:0045132 59 0.034
regulation of phosphate metabolic process GO:0019220 210 0.034
positive regulation of gene expression GO:0010628 290 0.033
tube development GO:0035295 244 0.031
carbohydrate derivative catabolic process GO:1901136 118 0.031
regulation of cellular response to stress GO:0080135 89 0.031
negative regulation of gene expression GO:0010629 387 0.031
neuron projection guidance GO:0097485 241 0.031
Fly
membrane organization GO:0061024 112 0.030
nucleoside metabolic process GO:0009116 127 0.030
nucleoside triphosphate metabolic process GO:0009141 120 0.029
organic acid metabolic process GO:0006082 103 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.028
regulation of mrna metabolic process GO:1903311 72 0.028
purine nucleoside metabolic process GO:0042278 127 0.028
ribonucleotide metabolic process GO:0009259 145 0.027
establishment of localization in cell GO:0051649 402 0.027
nucleotide catabolic process GO:0009166 109 0.027
regulation of multicellular organismal development GO:2000026 414 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
cellular macromolecular complex assembly GO:0034622 153 0.026
protein complex assembly GO:0006461 200 0.026
chromosome segregation GO:0007059 157 0.026
organophosphate catabolic process GO:0046434 112 0.026
response to organonitrogen compound GO:0010243 75 0.025
nucleoside phosphate catabolic process GO:1901292 110 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
phagocytosis GO:0006909 215 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
aromatic compound catabolic process GO:0019439 166 0.025
endomembrane system organization GO:0010256 119 0.025
positive regulation of programmed cell death GO:0043068 62 0.025
maintenance of location GO:0051235 73 0.025
Worm
cellular response to organic substance GO:0071310 132 0.025
ion homeostasis GO:0050801 55 0.024
regulation of cell development GO:0060284 215 0.024
negative regulation of cell differentiation GO:0045596 143 0.024
negative regulation of intracellular signal transduction GO:1902532 57 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.024
actin cytoskeleton organization GO:0030036 206 0.024
male gamete generation GO:0048232 201 0.024
nucleoside triphosphate catabolic process GO:0009143 108 0.024
oxoacid metabolic process GO:0043436 103 0.024
phosphorylation GO:0016310 294 0.024
Fly
cellular amino acid metabolic process GO:0006520 61 0.023
dna repair GO:0006281 54 0.023
determination of adult lifespan GO:0008340 137 0.023
positive regulation of signal transduction GO:0009967 223 0.023
Fly
organic substance catabolic process GO:1901575 308 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
protein dna complex subunit organization GO:0071824 86 0.022
ribose phosphate metabolic process GO:0019693 145 0.022
cellular response to chemical stimulus GO:0070887 199 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
secretion GO:0046903 109 0.022
regulation of localization GO:0032879 275 0.022
purine nucleotide catabolic process GO:0006195 109 0.022
lipid metabolic process GO:0006629 121 0.021
response to external biotic stimulus GO:0043207 293 0.021
macromolecular complex assembly GO:0065003 256 0.021
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
regulation of tor signaling GO:0032006 21 0.021
response to other organism GO:0051707 293 0.021
defense response to gram negative bacterium GO:0050829 94 0.021
cellular homeostasis GO:0019725 80 0.021
metal ion transport GO:0030001 74 0.020
proteolysis GO:0006508 192 0.020
response to endoplasmic reticulum stress GO:0034976 28 0.020
negative regulation of cell cycle GO:0045786 116 0.020
negative regulation of signal transduction GO:0009968 206 0.020
protein modification process GO:0036211 438 0.020
Fly
spindle organization GO:0007051 253 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
glycosyl compound catabolic process GO:1901658 112 0.019
positive regulation of transcription dna templated GO:0045893 266 0.019
sensory organ morphogenesis GO:0090596 260 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
response to abiotic stimulus GO:0009628 341 0.019
secretion by cell GO:0032940 101 0.018
regulation of cell differentiation GO:0045595 302 0.018
purine containing compound catabolic process GO:0072523 112 0.018
regulation of endocytosis GO:0030100 37 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
regulation of protein modification process GO:0031399 112 0.017
endosomal transport GO:0016197 44 0.017
defense response GO:0006952 300 0.017
regulation of vesicle mediated transport GO:0060627 59 0.017
organelle fission GO:0048285 340 0.017
single organism biosynthetic process GO:0044711 206 0.017
cellular metal ion homeostasis GO:0006875 31 0.017
cell death GO:0008219 279 0.017
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
appendage development GO:0048736 401 0.016
transition metal ion homeostasis GO:0055076 17 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
developmental programmed cell death GO:0010623 138 0.016
negative regulation of cell cycle process GO:0010948 109 0.016
microtubule organizing center organization GO:0031023 168 0.016
atp metabolic process GO:0046034 49 0.016
lipid storage GO:0019915 38 0.016
Worm
negative regulation of signaling GO:0023057 219 0.016
cellular response to endogenous stimulus GO:0071495 80 0.016
cation transport GO:0006812 110 0.015
mitochondrion organization GO:0007005 65 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
centrosome cycle GO:0007098 137 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
immune response GO:0006955 246 0.015
anion homeostasis GO:0055081 3 0.015
regulation of catabolic process GO:0009894 170 0.015
meiotic cell cycle process GO:1903046 132 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
Fly
positive regulation of cell death GO:0010942 69 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
response to endogenous stimulus GO:0009719 119 0.014
cellular ion homeostasis GO:0006873 39 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
negative regulation of notch signaling pathway GO:0045746 41 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
regulation of protein deacetylation GO:0090311 2 0.014
regulation of microtubule depolymerization GO:0031114 24 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
ras protein signal transduction GO:0007265 88 0.013
autophagy GO:0006914 108 0.013
g2 dna damage checkpoint GO:0031572 69 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
endocytic recycling GO:0032456 13 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
eye development GO:0001654 323 0.013
regulation of transport GO:0051049 181 0.013
response to decreased oxygen levels GO:0036293 58 0.013
negative regulation of molecular function GO:0044092 51 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
regulation of cell shape GO:0008360 113 0.013
body morphogenesis GO:0010171 2 0.013
cation homeostasis GO:0055080 51 0.013
connective tissue development GO:0061448 3 0.013
mrna metabolic process GO:0016071 124 0.012
cellular response to nitrogen compound GO:1901699 51 0.012
actin filament organization GO:0007015 126 0.012
negative regulation of cell communication GO:0010648 223 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
response to biotic stimulus GO:0009607 294 0.012
regulation of cell death GO:0010941 173 0.012
regulation of rna splicing GO:0043484 69 0.012
programmed cell death GO:0012501 257 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
spermatid differentiation GO:0048515 114 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
dendrite morphogenesis GO:0048813 199 0.012
regulation of cell proliferation GO:0042127 163 0.012
cellular ketone metabolic process GO:0042180 24 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
regulation of multi organism process GO:0043900 131 0.012
negative regulation of growth GO:0045926 84 0.012
notch signaling pathway GO:0007219 120 0.012
regulation of molecular function GO:0065009 217 0.012
regulation of cell cycle GO:0051726 291 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.011
cell motility GO:0048870 251 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
regulation of programmed cell death GO:0043067 152 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
dna conformation change GO:0071103 105 0.011
regulation of apoptotic process GO:0042981 130 0.011
metal ion homeostasis GO:0055065 44 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
skeletal muscle fiber development GO:0048741 3 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
purine nucleoside monophosphate catabolic process GO:0009128 38 0.011
rna splicing GO:0008380 83 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
regulation of hydrolase activity GO:0051336 97 0.011
gene silencing GO:0016458 138 0.011
axon guidance GO:0007411 233 0.011
Fly
cellular protein modification process GO:0006464 438 0.011
Fly
death GO:0016265 284 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
negative regulation of cellular biosynthetic process GO:0031327 277 0.010
cell cycle arrest GO:0007050 4 0.010
cellular cation homeostasis GO:0030003 38 0.010
molting cycle GO:0042303 56 0.010
apoptotic process GO:0006915 159 0.010
tissue death GO:0016271 102 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
negative regulation of cell cycle phase transition GO:1901988 103 0.010
guanosine containing compound catabolic process GO:1901069 74 0.010
single organism intracellular transport GO:1902582 207 0.010
Human
hippo signaling GO:0035329 20 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
positive regulation of cell communication GO:0010647 250 0.010
Fly
rna processing GO:0006396 147 0.010

Madm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.011
disease of anatomical entity DOID:7 0 0.011