Drosophila melanogaster

51 known processes

Npc2b (Dmel_CG3153)

Niemann-Pick type C-2b

(Aliases: npc2b,Dmel\CG3153,CG3153,CT10556,DmML2)

Npc2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lateral inhibition GO:0046331 206 0.083
cell cell signaling involved in cell fate commitment GO:0045168 210 0.070
courtship behavior GO:0007619 68 0.069
organonitrogen compound metabolic process GO:1901564 318 0.064
small molecule metabolic process GO:0044281 305 0.057
organic hydroxy compound metabolic process GO:1901615 83 0.053
carboxylic acid metabolic process GO:0019752 92 0.048
hormone catabolic process GO:0042447 3 0.047
single organism biosynthetic process GO:0044711 206 0.046
response to extracellular stimulus GO:0009991 116 0.046
response to abiotic stimulus GO:0009628 341 0.046
catabolic process GO:0009056 409 0.046
cell death GO:0008219 279 0.045
response to nutrient levels GO:0031667 114 0.042
mating behavior GO:0007617 106 0.041
single organism catabolic process GO:0044712 228 0.040
response to radiation GO:0009314 155 0.039
adult behavior GO:0030534 137 0.038
cellular amide metabolic process GO:0043603 80 0.035
single organism behavior GO:0044708 391 0.033
phagocytosis GO:0006909 215 0.032
detection of light stimulus GO:0009583 58 0.031
tube morphogenesis GO:0035239 191 0.031
multicellular organismal aging GO:0010259 140 0.031
adult feeding behavior GO:0008343 13 0.030
response to organic substance GO:0010033 284 0.030
regionalization GO:0003002 416 0.029
organonitrogen compound biosynthetic process GO:1901566 117 0.029
cell division GO:0051301 248 0.028
organic substance catabolic process GO:1901575 308 0.028
spindle assembly GO:0051225 80 0.028
positive regulation of cell communication GO:0010647 250 0.027
oxoacid metabolic process GO:0043436 103 0.027
lipid metabolic process GO:0006629 121 0.026
response to external biotic stimulus GO:0043207 293 0.025
Fly
detection of stimulus GO:0051606 156 0.025
response to light stimulus GO:0009416 124 0.025
male mating behavior GO:0060179 70 0.025
nuclear division GO:0000280 332 0.024
macromolecular complex assembly GO:0065003 256 0.023
phosphorylation GO:0016310 294 0.022
aging GO:0007568 143 0.022
imaginal disc derived appendage morphogenesis GO:0035114 395 0.021
phototransduction GO:0007602 52 0.021
positive regulation of signaling GO:0023056 243 0.021
vesicle mediated transport GO:0016192 381 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
regulation of catalytic activity GO:0050790 185 0.020
cellular response to light stimulus GO:0071482 37 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
cell proliferation GO:0008283 299 0.019
protein modification process GO:0036211 438 0.019
biological adhesion GO:0022610 138 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
male courtship behavior GO:0008049 63 0.018
regulation of immune response GO:0050776 118 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
very long chain fatty acid metabolic process GO:0000038 4 0.018
multi organism reproductive behavior GO:0044705 121 0.018
ethanolamine containing compound metabolic process GO:0042439 4 0.018
cytokinesis GO:0000910 90 0.018
phosphatidic acid metabolic process GO:0046473 1 0.018
organelle fission GO:0048285 340 0.018
appendage development GO:0048736 401 0.018
androgen metabolic process GO:0008209 1 0.017
spindle organization GO:0007051 253 0.017
wing disc morphogenesis GO:0007472 344 0.017
cell adhesion GO:0007155 136 0.017
pigment metabolic process involved in pigmentation GO:0043474 33 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
organic acid metabolic process GO:0006082 103 0.017
defense response to other organism GO:0098542 225 0.017
Fly
actin filament based process GO:0030029 220 0.017
organic substance transport GO:0071702 257 0.016
cellular amine metabolic process GO:0044106 12 0.016
appendage morphogenesis GO:0035107 397 0.016
long chain fatty acid metabolic process GO:0001676 3 0.016
neurological system process GO:0050877 358 0.016
protein complex biogenesis GO:0070271 201 0.016
regulation of protein metabolic process GO:0051246 256 0.016
intracellular signal transduction GO:0035556 300 0.016
rhythmic process GO:0048511 106 0.016
cellular catabolic process GO:0044248 372 0.015
positive regulation of immune response GO:0050778 63 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
regulation of immune system process GO:0002682 176 0.015
death GO:0016265 284 0.015
mating GO:0007618 120 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
camera type eye development GO:0043010 4 0.015
fat soluble vitamin metabolic process GO:0006775 1 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
positive regulation of signal transduction GO:0009967 223 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
oxidation reduction process GO:0055114 123 0.014
negative regulation of cell death GO:0060548 81 0.014
detection of external stimulus GO:0009581 66 0.014
endocytosis GO:0006897 310 0.014
glutathione metabolic process GO:0006749 37 0.014
open tracheal system development GO:0007424 204 0.014
regulation of molecular function GO:0065009 217 0.014
steroid catabolic process GO:0006706 1 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
organelle assembly GO:0070925 198 0.014
meiotic nuclear division GO:0007126 151 0.014
respiratory system development GO:0060541 213 0.014
pigment biosynthetic process GO:0046148 36 0.014
negative regulation of gene expression GO:0010629 387 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.013
regulation of cell cycle GO:0051726 291 0.013
body morphogenesis GO:0010171 2 0.013
regulation of hydrolase activity GO:0051336 97 0.013
ras protein signal transduction GO:0007265 88 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.013
cellular protein modification process GO:0006464 438 0.013
axonogenesis GO:0007409 290 0.013
meiotic cell cycle process GO:1903046 132 0.013
synaptic transmission GO:0007268 288 0.013
protein complex assembly GO:0006461 200 0.013
vitamin metabolic process GO:0006766 2 0.013
organophosphate metabolic process GO:0019637 195 0.013
localization of cell GO:0051674 257 0.013
regulation of cell proliferation GO:0042127 163 0.012
behavioral response to starvation GO:0042595 6 0.012
positive regulation of lipid storage GO:0010884 4 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
molting cycle chitin based cuticle GO:0007591 56 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
cellular response to high light intensity GO:0071486 1 0.012
axon development GO:0061564 297 0.012
axis specification GO:0009798 167 0.012
negative regulation of cellular component organization GO:0051129 108 0.011
regulation of cell differentiation GO:0045595 302 0.011
regulation of humoral immune response GO:0002920 51 0.011
dorsal ventral axis specification GO:0009950 66 0.011
response to lipopolysaccharide GO:0032496 4 0.011
regulation of localization GO:0032879 275 0.011
cellular homeostasis GO:0019725 80 0.011
response to biotic stimulus GO:0009607 294 0.011
Fly
detection of abiotic stimulus GO:0009582 66 0.011
programmed cell death GO:0012501 257 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
response to virus GO:0009615 28 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
regulation of antimicrobial humoral response GO:0002759 50 0.011
acetylcholine metabolic process GO:0008291 2 0.011
regulation of anatomical structure size GO:0090066 163 0.011
developmental pigmentation GO:0048066 68 0.011
small molecule biosynthetic process GO:0044283 37 0.011
chromosome segregation GO:0007059 157 0.010
positive regulation of molecular function GO:0044093 136 0.010
amine metabolic process GO:0009308 12 0.010
segmentation GO:0035282 207 0.010
protein processing GO:0016485 68 0.010
response to starvation GO:0042594 97 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
regulation of cell death GO:0010941 173 0.010
regulation of multicellular organismal development GO:2000026 414 0.010
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.010
neuron projection guidance GO:0097485 241 0.010
salivary gland cell autophagic cell death GO:0035071 83 0.010
very long chain fatty acid biosynthetic process GO:0042761 2 0.010
positive regulation of macromolecule metabolic process GO:0010604 405 0.010

Npc2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.011
sensory system disease DOID:0050155 0 0.010