Drosophila melanogaster

122 known processes

hdc (Dmel_CG15532)

headcase

(Aliases: Dmel\CG15532,Hdc,CG15532,l(3)B4-3-20)

hdc biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
photoreceptor cell differentiation GO:0046530 170 0.889
eye photoreceptor cell differentiation GO:0001754 145 0.832
compound eye photoreceptor cell differentiation GO:0001751 140 0.609
positive regulation of transcription dna templated GO:0045893 266 0.602
gliogenesis GO:0042063 80 0.580
compound eye photoreceptor development GO:0042051 78 0.550
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.503
synaptic transmission GO:0007268 288 0.419
aggressive behavior GO:0002118 63 0.366
chromosome organization GO:0051276 360 0.333
compound eye development GO:0048749 307 0.259
protein phosphorylation GO:0006468 169 0.227
regulation of localization GO:0032879 275 0.212
r7 cell differentiation GO:0045466 43 0.196
regulation of anatomical structure morphogenesis GO:0022603 242 0.183
circadian rhythm GO:0007623 105 0.164
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.159
multi organism behavior GO:0051705 175 0.152
adult behavior GO:0030534 137 0.151
photoreceptor cell development GO:0042461 96 0.148
multicellular organismal reproductive behavior GO:0033057 110 0.146
developmental maturation GO:0021700 172 0.146
developmental programmed cell death GO:0010623 138 0.144
open tracheal system development GO:0007424 204 0.142
regulation of transport GO:0051049 181 0.134
glial cell migration GO:0008347 31 0.133
exocrine system development GO:0035272 162 0.132
neuron recognition GO:0008038 101 0.129
regulation of behavior GO:0050795 75 0.127
eye photoreceptor cell development GO:0042462 81 0.126
axon development GO:0061564 297 0.120
regulation of neurogenesis GO:0050767 158 0.117
eye photoreceptor cell fate commitment GO:0042706 37 0.116
regulation of neuron differentiation GO:0045664 103 0.116
regulation of cell development GO:0060284 215 0.115
mating behavior GO:0007617 106 0.112
regulation of cellular localization GO:0060341 136 0.106
regulation of oocyte development GO:0060281 27 0.104
oxoacid metabolic process GO:0043436 103 0.100
positive regulation of macromolecule metabolic process GO:0010604 405 0.100
protein catabolic process GO:0030163 101 0.089
tissue death GO:0016271 102 0.088
amine metabolic process GO:0009308 12 0.085
single organism intracellular transport GO:1902582 207 0.084
response to endogenous stimulus GO:0009719 119 0.083
compound eye photoreceptor fate commitment GO:0001752 36 0.079
catabolic process GO:0009056 409 0.075
tube morphogenesis GO:0035239 191 0.073
regulation of protein metabolic process GO:0051246 256 0.072
photoreceptor cell fate commitment GO:0046552 41 0.070
regulation of r7 cell differentiation GO:0045676 15 0.070
appendage development GO:0048736 401 0.069
maintenance of location GO:0051235 73 0.066
cellular protein modification process GO:0006464 438 0.065
tube development GO:0035295 244 0.061
cytoplasmic transport GO:0016482 130 0.060
oocyte maturation GO:0001556 3 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.059
positive regulation of rna biosynthetic process GO:1902680 266 0.058
compound eye cone cell differentiation GO:0042675 13 0.057
response to nutrient levels GO:0031667 114 0.057
sex differentiation GO:0007548 81 0.056
regulation of cellular amino acid metabolic process GO:0006521 0 0.056
cellular amine metabolic process GO:0044106 12 0.052
cellular response to dna damage stimulus GO:0006974 223 0.050
taxis GO:0042330 304 0.050
positive regulation of nucleic acid templated transcription GO:1903508 266 0.050
transcription from rna polymerase ii promoter GO:0006366 368 0.050
pole plasm mrna localization GO:0019094 49 0.048
neuron fate commitment GO:0048663 50 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.048
imaginal disc derived appendage morphogenesis GO:0035114 395 0.048
inter male aggressive behavior GO:0002121 60 0.047
phosphorylation GO:0016310 294 0.046
intercellular transport GO:0010496 2 0.045
learning or memory GO:0007611 141 0.043
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.042
eye development GO:0001654 323 0.040
synapse assembly GO:0007416 143 0.040
localization of cell GO:0051674 257 0.040
positive regulation of cell communication GO:0010647 250 0.040
detection of stimulus GO:0051606 156 0.039
eye morphogenesis GO:0048592 260 0.038
central nervous system development GO:0007417 201 0.037
autophagic cell death GO:0048102 83 0.037
regulation of synaptic transmission GO:0050804 69 0.037
regulation of cellular amine metabolic process GO:0033238 3 0.036
lateral inhibition GO:0046331 206 0.036
r7 cell fate commitment GO:0007465 12 0.036
olfactory behavior GO:0042048 97 0.036
regulation of multicellular organismal development GO:2000026 414 0.035
negative regulation of signaling GO:0023057 219 0.035
regulation of establishment of protein localization GO:0070201 61 0.035
response to radiation GO:0009314 155 0.035
cell motility GO:0048870 251 0.035
salivary gland histolysis GO:0035070 88 0.034
mitotic cytokinesis GO:0000281 50 0.033
negative regulation of cellular protein metabolic process GO:0032269 85 0.033
positive regulation of r7 cell differentiation GO:0045678 7 0.031
response to light stimulus GO:0009416 124 0.030
positive regulation of synaptic transmission GO:0050806 15 0.030
regulation of membrane potential GO:0042391 35 0.030
phenol containing compound metabolic process GO:0018958 57 0.030
response to abiotic stimulus GO:0009628 341 0.030
compound eye cone cell fate commitment GO:0042676 5 0.029
positive regulation of protein metabolic process GO:0051247 128 0.029
regulation of embryonic development GO:0045995 68 0.029
negative regulation of cell differentiation GO:0045596 143 0.028
regulation of phosphorus metabolic process GO:0051174 210 0.028
chemosensory behavior GO:0007635 106 0.028
response to other organism GO:0051707 293 0.027
imaginal disc derived appendage development GO:0048737 399 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
negative regulation of response to stimulus GO:0048585 258 0.027
g protein coupled receptor signaling pathway GO:0007186 136 0.027
gland development GO:0048732 191 0.027
cell junction organization GO:0034330 57 0.026
regulation of reproductive process GO:2000241 54 0.026
detection of external stimulus GO:0009581 66 0.025
negative regulation of molecular function GO:0044092 51 0.025
death GO:0016265 284 0.025
aging GO:0007568 143 0.024
salivary gland cell autophagic cell death GO:0035071 83 0.024
cell proliferation GO:0008283 299 0.024
organic substance catabolic process GO:1901575 308 0.023
protein import into nucleus GO:0006606 51 0.023
regulation of photoreceptor cell differentiation GO:0046532 34 0.022
associative learning GO:0008306 65 0.022
cognition GO:0050890 141 0.022
reproductive behavior GO:0019098 122 0.022
cellular component assembly involved in morphogenesis GO:0010927 151 0.021
cell aging GO:0007569 2 0.021
oocyte anterior posterior axis specification GO:0007314 72 0.021
chromatin organization GO:0006325 207 0.021
salivary gland development GO:0007431 162 0.021
muscle structure development GO:0061061 224 0.021
negative regulation of signal transduction GO:0009968 206 0.020
courtship behavior GO:0007619 68 0.020
telencephalon development GO:0021537 2 0.020
positive regulation of gene expression GO:0010628 290 0.020
protein localization GO:0008104 284 0.020
neuron neuron synaptic transmission GO:0007270 14 0.019
macromolecule catabolic process GO:0009057 161 0.019
organic substance transport GO:0071702 257 0.019
multi multicellular organism process GO:0044706 123 0.019
regulation of phosphorylation GO:0042325 147 0.019
cellular response to endogenous stimulus GO:0071495 80 0.018
covalent chromatin modification GO:0016569 106 0.018
male mating behavior GO:0060179 70 0.018
regulation of response to stress GO:0080134 200 0.017
retina development in camera type eye GO:0060041 4 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
cell division GO:0051301 248 0.017
negative regulation of phosphorylation GO:0042326 35 0.017
lipid storage GO:0019915 38 0.017
growth GO:0040007 359 0.017
neurological system process GO:0050877 358 0.017
protein import GO:0017038 55 0.017
axis specification GO:0009798 167 0.017
multi organism reproductive behavior GO:0044705 121 0.017
regulation of anatomical structure size GO:0090066 163 0.017
endomembrane system organization GO:0010256 119 0.017
oocyte differentiation GO:0009994 145 0.017
protein modification process GO:0036211 438 0.016
release of sequestered calcium ion into cytosol GO:0051209 1 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
intracellular signal transduction GO:0035556 300 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
regulation of nervous system development GO:0051960 248 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
striated muscle cell differentiation GO:0051146 90 0.016
delamination GO:0060232 8 0.016
cellular macromolecule localization GO:0070727 220 0.016
chromatin modification GO:0016568 147 0.015
peptidyl amino acid modification GO:0018193 105 0.015
cell maturation GO:0048469 144 0.015
programmed cell death GO:0012501 257 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
notch signaling pathway GO:0007219 120 0.015
negative regulation of cell development GO:0010721 62 0.015
regulation of compound eye cone cell fate specification GO:0042682 4 0.015
locomotory behavior GO:0007626 176 0.015
circadian behavior GO:0048512 76 0.015
cranial nerve development GO:0021545 1 0.014
regulation of protein modification process GO:0031399 112 0.014
histolysis GO:0007559 102 0.014
single organism behavior GO:0044708 391 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
forebrain development GO:0030900 2 0.014
optic placode formation GO:0001743 4 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.014
compound eye retinal cell programmed cell death GO:0046667 23 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
larval development GO:0002164 104 0.014
establishment of localization in cell GO:0051649 402 0.013
response to oxygen containing compound GO:1901700 200 0.013
establishment of protein localization to plasma membrane GO:0090002 9 0.013
nucleus localization GO:0051647 34 0.013
adult locomotory behavior GO:0008344 76 0.013
autophagy GO:0006914 108 0.013
regulation of protein localization to plasma membrane GO:1903076 7 0.013
response to hormone GO:0009725 45 0.013
regulation of cell cell adhesion GO:0022407 21 0.013
neuromuscular synaptic transmission GO:0007274 67 0.013
neuron fate specification GO:0048665 12 0.013
nitrogen compound transport GO:0071705 85 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
negative regulation of cell communication GO:0010648 223 0.013
proteolysis GO:0006508 192 0.013
single organism cellular localization GO:1902580 180 0.013
positive regulation of neurotransmitter transport GO:0051590 2 0.013
embryonic morphogenesis GO:0048598 206 0.013
regulation of protein localization GO:0032880 76 0.012
dorsal ventral axis specification GO:0009950 66 0.012
cell junction assembly GO:0034329 42 0.012
compound eye morphogenesis GO:0001745 249 0.012
female germ line cyst formation GO:0048135 42 0.012
brain development GO:0007420 120 0.012
regulation of erbb signaling pathway GO:1901184 42 0.012
regulation of mapk cascade GO:0043408 92 0.012
germ line cyst formation GO:0048134 44 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
camera type eye morphogenesis GO:0048593 2 0.012
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.012
regulation of striated muscle contraction GO:0006942 2 0.012
peripheral nervous system development GO:0007422 52 0.012
regulation of transferase activity GO:0051338 58 0.012
phagocytosis GO:0006909 215 0.012
establishment of protein localization to organelle GO:0072594 62 0.012
dopamine biosynthetic process GO:0042416 3 0.012
regulation of circadian rhythm GO:0042752 49 0.012
chemotaxis GO:0006935 249 0.012
cellular protein catabolic process GO:0044257 83 0.011
response to ketone GO:1901654 34 0.011
cell cycle checkpoint GO:0000075 95 0.011
response to alcohol GO:0097305 95 0.011
positive regulation of binding GO:0051099 4 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
olfactory learning GO:0008355 56 0.011
translation GO:0006412 69 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
mesodermal cell fate specification GO:0007501 2 0.011
eye antennal disc development GO:0035214 60 0.011
detection of abiotic stimulus GO:0009582 66 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
photoreceptor cell fate specification GO:0043704 9 0.011
glial cell differentiation GO:0010001 35 0.011
regulation of molecular function GO:0065009 217 0.011
cellular response to biotic stimulus GO:0071216 4 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
epithelial cell development GO:0002064 274 0.010
regulation of cellular protein metabolic process GO:0032268 243 0.010

hdc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
auditory system disease DOID:2742 0 0.014
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.014
nonsyndromic deafness DOID:0050563 0 0.014
sensory system disease DOID:0050155 0 0.014
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014