Drosophila melanogaster

0 known processes

CG18745 (Dmel_CG18745)

CG18745 gene product from transcript CG18745-RA

(Aliases: Dmel\CG18745)

CG18745 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic appendage morphogenesis GO:0035120 385 0.788
appendage development GO:0048736 401 0.739
appendage morphogenesis GO:0035107 397 0.724
imaginal disc derived appendage development GO:0048737 399 0.687
imaginal disc derived appendage morphogenesis GO:0035114 395 0.556
wing disc morphogenesis GO:0007472 344 0.478
imaginal disc derived wing morphogenesis GO:0007476 337 0.369
acylglycerol biosynthetic process GO:0046463 2 0.257
triglyceride biosynthetic process GO:0019432 2 0.202
imaginal disc derived leg morphogenesis GO:0007480 80 0.201
leg disc development GO:0035218 92 0.161
response to other organism GO:0051707 293 0.128
anion homeostasis GO:0055081 3 0.125
positive regulation of sequestering of triglyceride GO:0010890 1 0.125
vesicle mediated transport GO:0016192 381 0.123
Fly
response to organonitrogen compound GO:0010243 75 0.114
catabolic process GO:0009056 409 0.114
homeostatic process GO:0042592 199 0.113
phospholipid homeostasis GO:0055091 1 0.109
organophosphate metabolic process GO:0019637 195 0.107
endocytosis GO:0006897 310 0.103
Fly
regulation of programmed cell death GO:0043067 152 0.102
cellular response to chemical stimulus GO:0070887 199 0.101
regulation of sequestering of triglyceride GO:0010889 3 0.100
cellular protein modification process GO:0006464 438 0.097
phagocytosis GO:0006909 215 0.095
Fly
anatomical structure homeostasis GO:0060249 97 0.091
neutral lipid biosynthetic process GO:0046460 2 0.090
cholesterol homeostasis GO:0042632 3 0.088
cellular catabolic process GO:0044248 372 0.085
response to external biotic stimulus GO:0043207 293 0.083
regulation of synapse assembly GO:0051963 94 0.082
lipid catabolic process GO:0016042 21 0.082
leg disc morphogenesis GO:0007478 80 0.081
septate junction assembly GO:0019991 26 0.080
epithelial structure maintenance GO:0010669 17 0.079
open tracheal system development GO:0007424 204 0.076
sterol homeostasis GO:0055092 4 0.073
regulation of apoptotic process GO:0042981 130 0.072
regulation of cell death GO:0010941 173 0.071
morphogenesis of an epithelium GO:0002009 276 0.071
cellular lipid catabolic process GO:0044242 16 0.071
response to biotic stimulus GO:0009607 294 0.069
small molecule metabolic process GO:0044281 305 0.067
tissue morphogenesis GO:0048729 297 0.066
synapse organization GO:0050808 196 0.066
segmentation GO:0035282 207 0.065
organonitrogen compound metabolic process GO:1901564 318 0.065
ethanolamine containing compound metabolic process GO:0042439 4 0.064
protein modification by small protein conjugation or removal GO:0070647 106 0.063
glycerolipid catabolic process GO:0046503 3 0.061
tissue homeostasis GO:0001894 36 0.061
multicellular organismal homeostasis GO:0048871 41 0.060
death GO:0016265 284 0.059
negative regulation of programmed cell death GO:0043069 72 0.057
response to oxygen containing compound GO:1901700 200 0.057
triglyceride catabolic process GO:0019433 3 0.054
ubiquitin dependent protein catabolic process GO:0006511 78 0.054
oxoacid metabolic process GO:0043436 103 0.053
carboxylic acid metabolic process GO:0019752 92 0.053
positive regulation of lipid storage GO:0010884 4 0.051
sulfur compound metabolic process GO:0006790 59 0.051
neurological system process GO:0050877 358 0.050
epithelial cell migration GO:0010631 148 0.050
centrosome cycle GO:0007098 137 0.048
cell proliferation GO:0008283 299 0.048
protein catabolic process GO:0030163 101 0.048
single organism catabolic process GO:0044712 228 0.047
acylglycerol catabolic process GO:0046464 3 0.046
cellular amino acid metabolic process GO:0006520 61 0.045
neutral lipid catabolic process GO:0046461 3 0.045
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.044
nucleoside phosphate metabolic process GO:0006753 162 0.044
cholesterol transport GO:0030301 2 0.043
response to nutrient levels GO:0031667 114 0.043
forebrain development GO:0030900 2 0.043
heart development GO:0007507 82 0.042
oxidoreduction coenzyme metabolic process GO:0006733 2 0.042
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.042
cell adhesion involved in heart morphogenesis GO:0061343 12 0.042
fatty acid biosynthetic process GO:0006633 6 0.041
apical junction assembly GO:0043297 32 0.039
regulation of tube size open tracheal system GO:0035151 43 0.039
organic substance catabolic process GO:1901575 308 0.039
cell cell junction organization GO:0045216 55 0.039
pyridine nucleotide metabolic process GO:0019362 2 0.038
synapse assembly GO:0007416 143 0.038
negative regulation of growth GO:0045926 84 0.037
regulation of synapse organization GO:0050807 110 0.036
chemical homeostasis GO:0048878 92 0.036
gland development GO:0048732 191 0.036
regulation of cholesterol transport GO:0032374 1 0.036
nucleobase containing small molecule metabolic process GO:0055086 174 0.035
single organism biosynthetic process GO:0044711 206 0.034
response to temperature stimulus GO:0009266 106 0.034
immune system process GO:0002376 347 0.034
organelle fission GO:0048285 340 0.034
heparan sulfate proteoglycan biosynthetic process GO:0015012 10 0.033
regulation of sterol transport GO:0032371 1 0.033
ion transmembrane transport GO:0034220 122 0.032
spindle organization GO:0007051 253 0.032
carbohydrate derivative catabolic process GO:1901136 118 0.032
regulation of lipid transport GO:0032368 3 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.032
cell cycle phase transition GO:0044770 140 0.032
cellular response to dna damage stimulus GO:0006974 223 0.031
rhythmic process GO:0048511 106 0.031
mitotic dna damage checkpoint GO:0044773 74 0.030
response to endogenous stimulus GO:0009719 119 0.030
actin filament based process GO:0030029 220 0.030
response to organic substance GO:0010033 284 0.030
negative regulation of multicellular organismal process GO:0051241 142 0.030
embryonic morphogenesis GO:0048598 206 0.029
glycoprotein biosynthetic process GO:0009101 41 0.029
transmembrane transport GO:0055085 139 0.029
cellular macromolecule catabolic process GO:0044265 136 0.029
organophosphate catabolic process GO:0046434 112 0.029
body morphogenesis GO:0010171 2 0.029
imaginal disc derived leg segmentation GO:0036011 26 0.028
proteasomal protein catabolic process GO:0010498 59 0.028
pyridine containing compound metabolic process GO:0072524 3 0.028
macromolecular complex assembly GO:0065003 256 0.027
protein modification process GO:0036211 438 0.027
response to copper ion GO:0046688 4 0.027
regulation of organelle organization GO:0033043 196 0.027
negative regulation of developmental process GO:0051093 201 0.026
spermatid differentiation GO:0048515 114 0.026
regulation of synapse structure and activity GO:0050803 128 0.026
modification dependent protein catabolic process GO:0019941 78 0.026
chaeta development GO:0022416 97 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.026
nicotinamide nucleotide metabolic process GO:0046496 2 0.026
ion homeostasis GO:0050801 55 0.026
positive regulation of nucleic acid templated transcription GO:1903508 266 0.025
centrosome organization GO:0051297 163 0.025
response to carbohydrate GO:0009743 15 0.025
developmental growth GO:0048589 280 0.025
chromosome organization GO:0051276 360 0.025
protein localization GO:0008104 284 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
defense response to bacterium GO:0042742 178 0.025
proteolysis GO:0006508 192 0.024
cell division GO:0051301 248 0.024
regulation of transport GO:0051049 181 0.024
response to extracellular stimulus GO:0009991 116 0.024
exocrine system development GO:0035272 162 0.024
multi multicellular organism process GO:0044706 123 0.024
cell adhesion GO:0007155 136 0.024
regulation of localization GO:0032879 275 0.023
phosphatidic acid metabolic process GO:0046473 1 0.023
limb development GO:0060173 1 0.023
cell junction organization GO:0034330 57 0.023
morphogenesis of embryonic epithelium GO:0016331 94 0.023
cell junction assembly GO:0034329 42 0.023
developmental maturation GO:0021700 172 0.023
organonitrogen compound biosynthetic process GO:1901566 117 0.022
spermatid development GO:0007286 98 0.022
phosphatidylethanolamine metabolic process GO:0046337 1 0.022
macromolecule catabolic process GO:0009057 161 0.022
wound healing GO:0042060 75 0.022
negative regulation of synapse assembly GO:0051964 39 0.022
cellular lipid metabolic process GO:0044255 83 0.022
dna packaging GO:0006323 91 0.021
response to peptide hormone GO:0043434 29 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.021
regulation of cytoskeleton organization GO:0051493 89 0.021
modification dependent macromolecule catabolic process GO:0043632 79 0.021
positive regulation of cell migration GO:0030335 2 0.021
dna metabolic process GO:0006259 227 0.021
glycoprotein metabolic process GO:0009100 41 0.020
heparan sulfate proteoglycan metabolic process GO:0030201 10 0.020
response to nitrogen compound GO:1901698 90 0.020
posttranscriptional regulation of gene expression GO:0010608 145 0.020
proteoglycan biosynthetic process GO:0030166 10 0.020
mitotic nuclear division GO:0007067 213 0.020
biological adhesion GO:0022610 138 0.020
cellular protein catabolic process GO:0044257 83 0.020
ovarian follicle cell development GO:0030707 248 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
meiosis i GO:0007127 59 0.020
developmental growth involved in morphogenesis GO:0060560 65 0.019
negative regulation of nervous system development GO:0051961 92 0.019
programmed cell death GO:0012501 257 0.019
regulation of tube architecture open tracheal system GO:0035152 68 0.019
mitotic cell cycle phase transition GO:0044772 138 0.019
positive regulation of gene expression GO:0010628 290 0.019
appendage segmentation GO:0035285 26 0.019
response to heat GO:0009408 63 0.019
male courtship behavior veined wing generated song production GO:0045433 20 0.019
telomere organization GO:0032200 21 0.019
negative regulation of cell proliferation GO:0008285 69 0.018
cardiovascular system development GO:0072358 82 0.018
negative regulation of cell cycle process GO:0010948 109 0.018
androgen metabolic process GO:0008209 1 0.018
mating GO:0007618 120 0.018
response to abiotic stimulus GO:0009628 341 0.017
negative regulation of cell death GO:0060548 81 0.017
learning or memory GO:0007611 141 0.017
cellular component assembly involved in morphogenesis GO:0010927 151 0.017
organic acid metabolic process GO:0006082 103 0.017
cellular modified amino acid metabolic process GO:0006575 45 0.017
response to wounding GO:0009611 94 0.017
response to lipopolysaccharide GO:0032496 4 0.017
response to acid chemical GO:0001101 25 0.016
actin filament organization GO:0007015 126 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
response to organophosphorus GO:0046683 2 0.016
negative regulation of mitotic cell cycle GO:0045930 109 0.016
chemotaxis GO:0006935 249 0.016
chromosome condensation GO:0030261 41 0.016
regulation of nervous system development GO:0051960 248 0.015
cell death GO:0008219 279 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
mitotic cell cycle checkpoint GO:0007093 88 0.015
axonogenesis GO:0007409 290 0.015
antimicrobial humoral response GO:0019730 99 0.015
telencephalon development GO:0021537 2 0.015
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.015
indole containing compound biosynthetic process GO:0042435 4 0.015
regulation of purine nucleotide metabolic process GO:1900542 62 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
nad metabolic process GO:0019674 1 0.015
regulation of protein metabolic process GO:0051246 256 0.015
growth GO:0040007 359 0.015
cellular ketone metabolic process GO:0042180 24 0.015
secondary metabolic process GO:0019748 75 0.015
asymmetric cell division GO:0008356 37 0.015
response to bacterium GO:0009617 198 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
cell maturation GO:0048469 144 0.015
cellular response to endogenous stimulus GO:0071495 80 0.014
carboxylic acid biosynthetic process GO:0046394 15 0.014
heart morphogenesis GO:0003007 32 0.014
cellular homeostasis GO:0019725 80 0.014
male courtship behavior veined wing extension GO:0048065 22 0.014
multi organism behavior GO:0051705 175 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.014
positive regulation of cell motility GO:2000147 3 0.014
reproductive behavior GO:0019098 122 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
regionalization GO:0003002 416 0.014
regulation of cell cycle GO:0051726 291 0.014
negative regulation of apoptotic process GO:0043066 63 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
digestive system development GO:0055123 149 0.014
vesicle organization GO:0016050 44 0.014
locomotory behavior GO:0007626 176 0.014
defense response to other organism GO:0098542 225 0.014
tissue migration GO:0090130 155 0.013
mitotic g2 dna damage checkpoint GO:0007095 69 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
salivary gland morphogenesis GO:0007435 145 0.013
protein complex biogenesis GO:0070271 201 0.013
response to peptide GO:1901652 29 0.013
cuticle development GO:0042335 86 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
synaptic growth at neuromuscular junction GO:0051124 119 0.013
eye antennal disc development GO:0035214 60 0.013
epithelium migration GO:0090132 148 0.013
regulation of molecular function GO:0065009 217 0.013
camera type eye development GO:0043010 4 0.013
axon development GO:0061564 297 0.013
cation transport GO:0006812 110 0.013
positive regulation of cell death GO:0010942 69 0.013
rho protein signal transduction GO:0007266 14 0.013
spinal cord development GO:0021510 1 0.013
regulation of cell cycle process GO:0010564 181 0.012
lipid storage GO:0019915 38 0.012
mitotic g2 m transition checkpoint GO:0044818 70 0.012
male courtship behavior veined wing vibration GO:0016545 21 0.012
egg activation GO:0007343 9 0.012
potassium ion transport GO:0006813 20 0.012
lipid metabolic process GO:0006629 121 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
convergent extension GO:0060026 2 0.012
gland morphogenesis GO:0022612 145 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
acylglycerol homeostasis GO:0055090 19 0.012
germ cell migration GO:0008354 43 0.012
peptidyl amino acid modification GO:0018193 105 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
circulatory system development GO:0072359 82 0.012
regulation of lipid storage GO:0010883 22 0.012
phosphatidylcholine metabolic process GO:0046470 3 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
membrane organization GO:0061024 112 0.012
regulation of cell proliferation GO:0042127 163 0.012
actin cytoskeleton organization GO:0030036 206 0.012
vitamin metabolic process GO:0006766 2 0.012
inorganic ion transmembrane transport GO:0098660 73 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
regulation of stress activated mapk cascade GO:0032872 41 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
cation transmembrane transport GO:0098655 88 0.011
salivary gland development GO:0007431 162 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
axon guidance GO:0007411 233 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
maintenance of location GO:0051235 73 0.011
protein phosphorylation GO:0006468 169 0.011
cellular amine metabolic process GO:0044106 12 0.011
cell fate specification GO:0001708 71 0.011
courtship behavior GO:0007619 68 0.011
cell projection assembly GO:0030031 94 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
actin filament bundle organization GO:0061572 28 0.011
rhabdomere development GO:0042052 38 0.011
regulation of cellular component size GO:0032535 98 0.011
oocyte development GO:0048599 124 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
decapentaplegic signaling pathway GO:0008101 19 0.011
regulation of reproductive process GO:2000241 54 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
dna conformation change GO:0071103 105 0.011
regulation of developmental growth GO:0048638 174 0.011
peptidyl proline modification GO:0018208 3 0.011
eggshell formation GO:0030703 105 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
nephron tubule development GO:0072080 3 0.011
response to monosaccharide GO:0034284 4 0.011
chromosome separation GO:0051304 42 0.011
regulation of phosphorylation GO:0042325 147 0.011
chromosome segregation GO:0007059 157 0.011
steroid catabolic process GO:0006706 1 0.011
autophagic cell death GO:0048102 83 0.011
small molecule biosynthetic process GO:0044283 37 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
cellular response to hormone stimulus GO:0032870 44 0.010
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.010
cellular response to organic substance GO:0071310 132 0.010
cell aging GO:0007569 2 0.010
jnk cascade GO:0007254 50 0.010
nucleotide metabolic process GO:0009117 161 0.010
negative regulation of cell cycle phase transition GO:1901988 103 0.010
limb morphogenesis GO:0035108 1 0.010
response to hexose GO:0009746 3 0.010
monocarboxylic acid transport GO:0015718 3 0.010
larval behavior GO:0030537 42 0.010
positive regulation of transport GO:0051050 92 0.010
regulation of imaginal disc derived wing size GO:0044719 20 0.010
tube morphogenesis GO:0035239 191 0.010

CG18745 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.105
familial hyperlipidemia DOID:1168 0 0.105
lipid metabolism disorder DOID:3146 0 0.105
familial combined hyperlipidemia DOID:13809 0 0.105
inherited metabolic disorder DOID:655 0 0.105
hair disease DOID:421 0 0.064
disease of anatomical entity DOID:7 0 0.064
integumentary system disease DOID:16 0 0.064
diabetes mellitus DOID:9351 0 0.060
type 2 diabetes mellitus DOID:9352 0 0.060
carbohydrate metabolism disease DOID:0050013 0 0.060
glucose metabolism disease DOID:4194 0 0.060
acquired metabolic disease DOID:0060158 0 0.060
familial lipoprotein lipase deficiency DOID:14118 0 0.039
familial hypertriglyceridemia DOID:0050527 0 0.030
vascular disease DOID:178 0 0.025
cardiovascular system disease DOID:1287 0 0.025
nervous system disease DOID:863 0 0.021
urinary system disease DOID:18 0 0.016
sensory system disease DOID:0050155 0 0.015
kidney disease DOID:557 0 0.013
hypertension DOID:10763 0 0.011
artery disease DOID:0050828 0 0.011