Drosophila melanogaster

30 known processes

LysE (Dmel_CG1180)

Lysozyme E

(Aliases: BcDNA:LP07339,Lys E,Dmel\CG1180,CG1180,lysE)

LysE biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single fertilization GO:0007338 24 0.775
Mouse
defense response GO:0006952 300 0.609
gland morphogenesis GO:0022612 145 0.444
Fly
regulation of defense response GO:0031347 102 0.439
defense response to gram positive bacterium GO:0050830 41 0.435
Mouse Rat
salivary gland development GO:0007431 162 0.428
Fly
histolysis GO:0007559 102 0.390
Fly
tissue death GO:0016271 102 0.388
Fly
innate immune response GO:0045087 144 0.345
anatomical structure homeostasis GO:0060249 97 0.329
Human
negative regulation of immune system process GO:0002683 50 0.305
exocrine system development GO:0035272 162 0.281
Fly
immune system process GO:0002376 347 0.280
defense response to bacterium GO:0042742 178 0.263
defense response to gram negative bacterium GO:0050829 94 0.254
immune response GO:0006955 246 0.249
salivary gland cell autophagic cell death GO:0035071 83 0.248
Fly
autophagic cell death GO:0048102 83 0.231
Fly
response to bacterium GO:0009617 198 0.227
negative regulation of response to stimulus GO:0048585 258 0.223
homeostatic process GO:0042592 199 0.216
Human
salivary gland histolysis GO:0035070 88 0.210
Fly
developmental programmed cell death GO:0010623 138 0.193
Fly
programmed cell death GO:0012501 257 0.183
Fly
regulation of immune system process GO:0002682 176 0.175
cell death GO:0008219 279 0.151
Fly
regulation of immune response GO:0050776 118 0.147
response to other organism GO:0051707 293 0.134
regulation of response to stress GO:0080134 200 0.128
tissue homeostasis GO:0001894 36 0.127
Human
death GO:0016265 284 0.125
Fly
negative regulation of defense response GO:0031348 35 0.099
imaginal disc derived wing morphogenesis GO:0007476 337 0.094
salivary gland morphogenesis GO:0007435 145 0.094
Fly
response to external biotic stimulus GO:0043207 293 0.079
multicellular organismal homeostasis GO:0048871 41 0.071
Human
fertilization GO:0009566 26 0.054
Mouse
appendage development GO:0048736 401 0.048
cell recognition GO:0008037 102 0.048
Mouse
retina homeostasis GO:0001895 13 0.047
Human
imaginal disc derived appendage development GO:0048737 399 0.042
appendage morphogenesis GO:0035107 397 0.039
positive regulation of response to stimulus GO:0048584 323 0.039
post embryonic appendage morphogenesis GO:0035120 385 0.039
gland development GO:0048732 191 0.038
Fly
wing disc morphogenesis GO:0007472 344 0.037
cholesterol homeostasis GO:0042632 3 0.036
imaginal disc derived appendage morphogenesis GO:0035114 395 0.033
regulation of multicellular organismal development GO:2000026 414 0.031
protein modification process GO:0036211 438 0.030
organonitrogen compound metabolic process GO:1901564 318 0.029
small molecule metabolic process GO:0044281 305 0.029
macromolecular complex assembly GO:0065003 256 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.028
cellular catabolic process GO:0044248 372 0.027
organic substance catabolic process GO:1901575 308 0.025
positive regulation of cell communication GO:0010647 250 0.024
response to organic substance GO:0010033 284 0.024
positive regulation of signaling GO:0023056 243 0.024
cellular protein modification process GO:0006464 438 0.023
catabolic process GO:0009056 409 0.023
amine metabolic process GO:0009308 12 0.022
organic substance transport GO:0071702 257 0.021
response to biotic stimulus GO:0009607 294 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
epithelial cell development GO:0002064 274 0.020
regulation of localization GO:0032879 275 0.019
intracellular signal transduction GO:0035556 300 0.018
phagocytosis GO:0006909 215 0.018
mitotic nuclear division GO:0007067 213 0.018
regionalization GO:0003002 416 0.018
sterol homeostasis GO:0055092 4 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
single organism biosynthetic process GO:0044711 206 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
cellular amine metabolic process GO:0044106 12 0.017
vesicle mediated transport GO:0016192 381 0.017
body morphogenesis GO:0010171 2 0.017
regulation of transport GO:0051049 181 0.016
growth GO:0040007 359 0.016
response to temperature stimulus GO:0009266 106 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
forebrain development GO:0030900 2 0.016
regulation of cell cycle GO:0051726 291 0.016
negative regulation of developmental process GO:0051093 201 0.016
positive regulation of lipid storage GO:0010884 4 0.015
phosphorylation GO:0016310 294 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
single organism catabolic process GO:0044712 228 0.015
negative regulation of innate immune response GO:0045824 30 0.015
regulation of cell development GO:0060284 215 0.015
response to lipopolysaccharide GO:0032496 4 0.015
positive regulation of signal transduction GO:0009967 223 0.015
response to oxygen containing compound GO:1901700 200 0.015
ovarian follicle cell development GO:0030707 248 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
organic hydroxy compound metabolic process GO:1901615 83 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
response to extracellular stimulus GO:0009991 116 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.015
oxoacid metabolic process GO:0043436 103 0.015
intracellular transport GO:0046907 228 0.015
organic acid metabolic process GO:0006082 103 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.014
kidney development GO:0001822 3 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
epithelial cell differentiation GO:0030855 322 0.014
negative regulation of gene expression GO:0010629 387 0.014
protein localization GO:0008104 284 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
protein complex biogenesis GO:0070271 201 0.014
pigment metabolic process GO:0042440 84 0.014
negative regulation of signaling GO:0023057 219 0.014
morphogenesis of an epithelium GO:0002009 276 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
regulation of cell differentiation GO:0045595 302 0.013
cellular response to organic substance GO:0071310 132 0.013
establishment of localization in cell GO:0051649 402 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.012
telencephalon development GO:0021537 2 0.012
immune response activating signal transduction GO:0002757 2 0.012
segmentation GO:0035282 207 0.012
cell division GO:0051301 248 0.012
negative regulation of signal transduction GO:0009968 206 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
eggshell formation GO:0030703 105 0.012
positive regulation of transport GO:0051050 92 0.012
protein transport GO:0015031 155 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
proteolysis GO:0006508 192 0.011
notch signaling pathway GO:0007219 120 0.011
cell proliferation GO:0008283 299 0.011
cellular macromolecule localization GO:0070727 220 0.011
macromolecule catabolic process GO:0009057 161 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
organophosphate metabolic process GO:0019637 195 0.011
regulation of molecular function GO:0065009 217 0.011
single organism intracellular transport GO:1902582 207 0.010
negative regulation of immune response GO:0050777 39 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
ethanolamine containing compound metabolic process GO:0042439 4 0.010
cholesterol transport GO:0030301 2 0.010
defense response to other organism GO:0098542 225 0.010
regulation of organelle organization GO:0033043 196 0.010
regulation of sterol transport GO:0032371 1 0.010
neurological system process GO:0050877 358 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
negative regulation of cell communication GO:0010648 223 0.010

LysE disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.999
Human
amyloidosis DOID:9120 0 0.999
Human
acquired metabolic disease DOID:0060158 0 0.999
Human
familial visceral amyloidosis DOID:0050636 0 0.999
Human
disease of anatomical entity DOID:7 0 0.028
inherited metabolic disorder DOID:655 0 0.019
familial hyperlipidemia DOID:1168 0 0.011
lipid metabolism disorder DOID:3146 0 0.011
familial combined hyperlipidemia DOID:13809 0 0.011
familial lipoprotein lipase deficiency DOID:14118 0 0.011
hair disease DOID:421 0 0.011
integumentary system disease DOID:16 0 0.011
hypotrichosis DOID:4535 0 0.011