Drosophila melanogaster

2 known processes

kdn (Dmel_CG3861)

knockdown

(Aliases: Dmel\CG3861,l(1)G0159,BEST:GM01832,l(1)G0030,l(1)G0033,Csyn,CS,CG3861)

kdn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mechanosensory behavior GO:0007638 12 0.849
response to mechanical stimulus GO:0009612 28 0.738
rhythmic excitation GO:0043179 1 0.485
single organism behavior GO:0044708 391 0.414
transmembrane transport GO:0055085 139 0.397
inorganic cation transmembrane transport GO:0098662 61 0.212
response to abiotic stimulus GO:0009628 341 0.204
cation transmembrane transport GO:0098655 88 0.203
protein localization GO:0008104 284 0.196
multi organism behavior GO:0051705 175 0.161
cell proliferation GO:0008283 299 0.147
metal ion transport GO:0030001 74 0.098
aggressive behavior GO:0002118 63 0.098
establishment of localization in cell GO:0051649 402 0.096
regulation of localization GO:0032879 275 0.095
synapse organization GO:0050808 196 0.094
positive regulation of signaling GO:0023056 243 0.094
ion transmembrane transport GO:0034220 122 0.087
positive regulation of cell communication GO:0010647 250 0.083
ion transport GO:0006811 145 0.083
homeostatic process GO:0042592 199 0.079
neuron neuron synaptic transmission GO:0007270 14 0.077
cation transport GO:0006812 110 0.072
developmental maturation GO:0021700 172 0.068
cellular protein modification process GO:0006464 438 0.064
establishment of organelle localization GO:0051656 122 0.061
inorganic ion transmembrane transport GO:0098660 73 0.061
morphogenesis of an epithelium GO:0002009 276 0.060
potassium ion transport GO:0006813 20 0.059
reproductive behavior GO:0019098 122 0.058
monovalent inorganic cation transport GO:0015672 40 0.058
positive regulation of synaptic transmission GO:0050806 15 0.057
spermatid differentiation GO:0048515 114 0.056
regulation of cellular localization GO:0060341 136 0.056
cellular amide metabolic process GO:0043603 80 0.055
cellular cation homeostasis GO:0030003 38 0.051
post embryonic appendage morphogenesis GO:0035120 385 0.048
vesicle mediated transport GO:0016192 381 0.048
regulation of anatomical structure morphogenesis GO:0022603 242 0.048
synaptic transmission glutamatergic GO:0035249 7 0.046
detection of light stimulus GO:0009583 58 0.046
endocytosis GO:0006897 310 0.044
establishment of tissue polarity GO:0007164 87 0.044
wing disc morphogenesis GO:0007472 344 0.043
hormone metabolic process GO:0042445 33 0.043
organonitrogen compound metabolic process GO:1901564 318 0.042
cellular homeostasis GO:0019725 80 0.040
spermatid development GO:0007286 98 0.037
positive regulation of response to stimulus GO:0048584 323 0.036
multi organism reproductive behavior GO:0044705 121 0.035
regulation of synapse structure and activity GO:0050803 128 0.034
transition metal ion transport GO:0000041 16 0.034
establishment of protein localization GO:0045184 163 0.033
membrane organization GO:0061024 112 0.031
imaginal disc derived appendage morphogenesis GO:0035114 395 0.029
regulation of neurotransmitter secretion GO:0046928 14 0.028
single organism intracellular transport GO:1902582 207 0.028
detection of abiotic stimulus GO:0009582 66 0.028
regulation of cell shape GO:0008360 113 0.028
programmed cell death GO:0012501 257 0.028
cellular macromolecule localization GO:0070727 220 0.028
phagocytosis GO:0006909 215 0.027
carboxylic acid metabolic process GO:0019752 92 0.027
muscle organ development GO:0007517 127 0.026
male gamete generation GO:0048232 201 0.026
epithelial cell development GO:0002064 274 0.025
regulation of transport GO:0051049 181 0.025
appendage development GO:0048736 401 0.025
synaptic transmission GO:0007268 288 0.024
regulation of synaptic activity GO:0060025 9 0.024
peptide metabolic process GO:0006518 80 0.024
synaptic vesicle recycling GO:0036465 28 0.024
dorsal appendage formation GO:0046843 47 0.023
anion transmembrane transport GO:0098656 26 0.022
small molecule metabolic process GO:0044281 305 0.022
regulation of response to stress GO:0080134 200 0.022
molting cycle GO:0042303 56 0.021
humoral immune response GO:0006959 117 0.021
epithelial cell differentiation GO:0030855 322 0.021
death GO:0016265 284 0.021
protein modification process GO:0036211 438 0.020
developmental programmed cell death GO:0010623 138 0.020
lipid metabolic process GO:0006629 121 0.020
carbohydrate metabolic process GO:0005975 82 0.020
detection of external stimulus GO:0009581 66 0.020
regulation of cell cycle GO:0051726 291 0.019
response to radiation GO:0009314 155 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
adult locomotory behavior GO:0008344 76 0.019
inorganic anion transmembrane transport GO:0098661 14 0.018
tissue morphogenesis GO:0048729 297 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
positive regulation of signal transduction GO:0009967 223 0.018
organelle localization GO:0051640 148 0.018
regulation of membrane potential GO:0042391 35 0.018
single organism membrane organization GO:0044802 93 0.018
neuromuscular synaptic transmission GO:0007274 67 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
regulation of synaptic transmission GO:0050804 69 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.017
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.017
xenobiotic catabolic process GO:0042178 1 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
organic substance transport GO:0071702 257 0.016
oocyte construction GO:0007308 112 0.016
regulation of neurotransmitter transport GO:0051588 14 0.016
regulation of notch signaling pathway GO:0008593 100 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
tissue death GO:0016271 102 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
phosphorylation GO:0016310 294 0.016
purine nucleoside metabolic process GO:0042278 127 0.015
tube morphogenesis GO:0035239 191 0.015
multicellular organismal reproductive behavior GO:0033057 110 0.015
synaptic growth at neuromuscular junction GO:0051124 119 0.015
rhythmic synaptic transmission GO:0060024 2 0.015
imaginal disc derived appendage development GO:0048737 399 0.015
regulation of synapse assembly GO:0051963 94 0.015
morphogenesis of a polarized epithelium GO:0001738 93 0.015
mapk cascade GO:0000165 107 0.015
secretion GO:0046903 109 0.015
chloride transport GO:0006821 10 0.015
spermatogenesis GO:0007283 200 0.015
inter male aggressive behavior GO:0002121 60 0.014
asymmetric neuroblast division GO:0055059 33 0.014
protein transport GO:0015031 155 0.014
regulation of neuromuscular synaptic transmission GO:1900073 15 0.014
gastrulation involving germ band extension GO:0010004 36 0.014
regulation of secretion GO:0051046 44 0.014
guanosine containing compound catabolic process GO:1901069 74 0.014
imaginal disc derived wing morphogenesis GO:0007476 337 0.014
chorion containing eggshell formation GO:0007304 105 0.014
locomotory behavior GO:0007626 176 0.014
atp biosynthetic process GO:0006754 2 0.014
cellular hormone metabolic process GO:0034754 23 0.014
notch signaling pathway GO:0007219 120 0.014
translation GO:0006412 69 0.013
sodium ion transport GO:0006814 22 0.013
regulation of cell death GO:0010941 173 0.013
ion homeostasis GO:0050801 55 0.013
cellular protein localization GO:0034613 160 0.013
cell death GO:0008219 279 0.013
synaptic vesicle transport GO:0048489 50 0.013
adult behavior GO:0030534 137 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
secretion by cell GO:0032940 101 0.013
steroid catabolic process GO:0006706 1 0.013
ribonucleoside catabolic process GO:0042454 112 0.012
pigmentation GO:0043473 75 0.012
flight behavior GO:0007629 26 0.012
chaeta development GO:0022416 97 0.012
regulation of necrotic cell death GO:0010939 1 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
olfactory behavior GO:0042048 97 0.012
cortical cytoskeleton organization GO:0030865 29 0.012
growth GO:0040007 359 0.012
protein import GO:0017038 55 0.012
intracellular transport GO:0046907 228 0.012
salivary gland histolysis GO:0035070 88 0.012
segmentation GO:0035282 207 0.012
heterocycle catabolic process GO:0046700 166 0.012
negative regulation of biosynthetic process GO:0009890 277 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
regulation of programmed cell death GO:0043067 152 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
response to light stimulus GO:0009416 124 0.011
histolysis GO:0007559 102 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
response to starvation GO:0042594 97 0.011
purine containing compound catabolic process GO:0072523 112 0.011
lateral inhibition GO:0046331 206 0.011
single organism cellular localization GO:1902580 180 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
regulation of cell proliferation GO:0042127 163 0.011
signal transduction by phosphorylation GO:0023014 107 0.010
ethanolamine containing compound metabolic process GO:0042439 4 0.010
gamma aminobutyric acid signaling pathway GO:0007214 2 0.010
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
cellular chemical homeostasis GO:0055082 40 0.010
sperm individualization GO:0007291 48 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
compound eye morphogenesis GO:0001745 249 0.010
appendage morphogenesis GO:0035107 397 0.010
cation homeostasis GO:0055080 51 0.010

kdn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.066
urinary system disease DOID:18 0 0.066
kidney disease DOID:557 0 0.066
renal tubular transport disease DOID:447 0 0.027
bartter disease DOID:445 0 0.027
glucose metabolism disease DOID:4194 0 0.011
disease of metabolism DOID:0014667 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
acquired metabolic disease DOID:0060158 0 0.011