Drosophila melanogaster

97 known processes

sad (Dmel_CG14728)

shadow

(Aliases: Cyp315a1,315a1,CYP315A1,Sad,CG14728,Dmel\CG14728)

sad biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
taxis GO:0042330 304 0.621
axon guidance GO:0007411 233 0.593
tissue morphogenesis GO:0048729 297 0.590
axonogenesis GO:0007409 290 0.518
axon development GO:0061564 297 0.495
morphogenesis of an epithelium GO:0002009 276 0.485
embryo development ending in birth or egg hatching GO:0009792 152 0.471
dorsal closure GO:0007391 79 0.455
morphogenesis of embryonic epithelium GO:0016331 94 0.414
tube development GO:0035295 244 0.385
organic hydroxy compound biosynthetic process GO:1901617 21 0.376
epithelial cell development GO:0002064 274 0.361
Fly
digestive system development GO:0055123 149 0.357
head involution GO:0008258 35 0.342
embryonic morphogenesis GO:0048598 206 0.322
embryonic development via the syncytial blastoderm GO:0001700 148 0.303
columnar cuboidal epithelial cell development GO:0002066 249 0.291
Fly
ketone biosynthetic process GO:0042181 16 0.278
steroid biosynthetic process GO:0006694 16 0.277
cellular hormone metabolic process GO:0034754 23 0.272
alcohol metabolic process GO:0006066 25 0.263
ecdysone biosynthetic process GO:0006697 9 0.262
regulation of cardiac cell fate specification GO:2000043 8 0.218
motor neuron axon guidance GO:0008045 58 0.210
appendage development GO:0048736 401 0.209
regionalization GO:0003002 416 0.208
growth GO:0040007 359 0.203
Human Fly
ecdysteroid metabolic process GO:0045455 19 0.201
cuticle development GO:0042335 86 0.192
Fly
regulation of hormone levels GO:0010817 40 0.180
midgut development GO:0007494 23 0.177
organic hydroxy compound metabolic process GO:1901615 83 0.174
small molecule biosynthetic process GO:0044283 37 0.162
ecdysone metabolic process GO:0008205 11 0.155
lipid biosynthetic process GO:0008610 46 0.151
hormone metabolic process GO:0042445 33 0.149
epithelium migration GO:0090132 148 0.145
Fly
sterol biosynthetic process GO:0016126 9 0.125
regulation of growth GO:0040008 233 0.123
Human
ecdysteroid biosynthetic process GO:0045456 15 0.123
sterol metabolic process GO:0016125 12 0.120
nuclear division GO:0000280 332 0.119
small molecule metabolic process GO:0044281 305 0.118
digestive tract development GO:0048565 149 0.110
organelle fission GO:0048285 340 0.109
chemotaxis GO:0006935 249 0.107
steroid metabolic process GO:0008202 20 0.104
dendrite morphogenesis GO:0048813 199 0.103
single organism biosynthetic process GO:0044711 206 0.097
regulation of anatomical structure morphogenesis GO:0022603 242 0.096
cell motility GO:0048870 251 0.091
Fly
cellular ketone metabolic process GO:0042180 24 0.088
ovarian follicle cell migration GO:0007297 121 0.084
Fly
regulation of localization GO:0032879 275 0.084
developmental growth GO:0048589 280 0.080
Fly
tube morphogenesis GO:0035239 191 0.075
tissue migration GO:0090130 155 0.075
Fly
alcohol biosynthetic process GO:0046165 14 0.074
hormone biosynthetic process GO:0042446 20 0.072
lipid metabolic process GO:0006629 121 0.070
response to extracellular stimulus GO:0009991 116 0.069
Human Mouse Rat
response to organic substance GO:0010033 284 0.069
Human Mouse Rat
neuron projection guidance GO:0097485 241 0.068
epithelial cell differentiation GO:0030855 322 0.067
Human Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.067
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.065
Fly
cell migration GO:0016477 238 0.063
Fly
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.058
Fly
glandular epithelial cell differentiation GO:0002067 1 0.057
response to toxic substance GO:0009636 22 0.056
regulation of transport GO:0051049 181 0.052
regulation of anatomical structure size GO:0090066 163 0.051
gastrulation involving germ band extension GO:0010004 36 0.049
regulation of cell projection organization GO:0031344 92 0.046
digestive tract morphogenesis GO:0048546 127 0.044
regulation of nervous system development GO:0051960 248 0.044
actin filament based process GO:0030029 220 0.043
localization of cell GO:0051674 257 0.041
Fly
border follicle cell migration GO:0007298 113 0.039
Fly
regulation of synapse organization GO:0050807 110 0.037
negative regulation of cardiac cell fate specification GO:2000044 7 0.037
neurological system process GO:0050877 358 0.037
ameboidal type cell migration GO:0001667 151 0.037
Fly
regulation of multicellular organismal development GO:2000026 414 0.037
Human
regulation of organelle organization GO:0033043 196 0.035
Zebrafish
response to organic cyclic compound GO:0014070 89 0.031
Human Mouse
regulation of cell morphogenesis GO:0022604 163 0.031
response to oxygen containing compound GO:1901700 200 0.031
Human Mouse Rat
dendrite development GO:0016358 204 0.030
epithelial tube morphogenesis GO:0060562 88 0.029
regulation of cellular component size GO:0032535 98 0.029
establishment of localization in cell GO:0051649 402 0.028
cellular response to organic substance GO:0071310 132 0.028
Human Rat
chromosome segregation GO:0007059 157 0.027
chemical homeostasis GO:0048878 92 0.027
Human Mouse
death GO:0016265 284 0.027
embryonic hindgut morphogenesis GO:0048619 48 0.027
response to ddt GO:0046680 5 0.027
positive regulation of macromolecule metabolic process GO:0010604 405 0.027
positive regulation of axon extension GO:0045773 2 0.026
gland morphogenesis GO:0022612 145 0.024
ovarian follicle cell development GO:0030707 248 0.024
Fly
cellular response to oxygen containing compound GO:1901701 79 0.024
Human Rat
regulation of locomotion GO:0040012 42 0.024
body morphogenesis GO:0010171 2 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
cell division GO:0051301 248 0.023
cell death GO:0008219 279 0.023
regulation of axon guidance GO:1902667 10 0.023
protein modification process GO:0036211 438 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.023
regulation of cell adhesion GO:0030155 27 0.023
axis specification GO:0009798 167 0.022
central nervous system development GO:0007417 201 0.022
developmental programmed cell death GO:0010623 138 0.022
positive regulation of programmed cell death GO:0043068 62 0.022
positive regulation of gene expression GO:0010628 290 0.021
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.021
asymmetric cell division GO:0008356 37 0.021
mitotic nuclear division GO:0007067 213 0.021
regulation of cell development GO:0060284 215 0.020
segmentation GO:0035282 207 0.020
negative regulation of transcription dna templated GO:0045892 237 0.020
negative regulation of cell communication GO:0010648 223 0.020
r8 cell fate commitment GO:0007460 6 0.020
detection of stimulus GO:0051606 156 0.020
actin cytoskeleton organization GO:0030036 206 0.019
connective tissue development GO:0061448 3 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
Human
negative regulation of growth GO:0045926 84 0.019
Human
regulation of synapse assembly GO:0051963 94 0.019
synaptic transmission GO:0007268 288 0.019
negative regulation of biosynthetic process GO:0009890 277 0.019
Human
regulation of embryonic development GO:0045995 68 0.018
reproductive system development GO:0061458 74 0.018
Human
imaginal disc derived appendage development GO:0048737 399 0.018
sensory perception of smell GO:0007608 80 0.018
regulation of cell growth GO:0001558 43 0.018
Human
gene silencing GO:0016458 138 0.018
appendage morphogenesis GO:0035107 397 0.018
negative regulation of cellular component organization GO:0051129 108 0.018
cellular response to endogenous stimulus GO:0071495 80 0.018
Human Rat
negative regulation of gene expression GO:0010629 387 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.017
positive regulation of cell death GO:0010942 69 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
Human
determination of adult lifespan GO:0008340 137 0.017
regulation of neurogenesis GO:0050767 158 0.017
regulation of neuron projection development GO:0010975 69 0.017
aggressive behavior GO:0002118 63 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
positive regulation of growth GO:0045927 75 0.017
peripheral nervous system development GO:0007422 52 0.017
compound eye morphogenesis GO:0001745 249 0.016
regulation of small gtpase mediated signal transduction GO:0051056 93 0.016
regulation of response to external stimulus GO:0032101 115 0.016
Human
cell adhesion GO:0007155 136 0.016
cardiac cell fate commitment GO:0060911 17 0.016
stem cell fate commitment GO:0048865 25 0.016
epithelial cell migration open tracheal system GO:0007427 32 0.016
regulation of apoptotic process GO:0042981 130 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
urogenital system development GO:0001655 72 0.016
sensory perception GO:0007600 196 0.015
cellular catabolic process GO:0044248 372 0.015
Mouse
organelle assembly GO:0070925 198 0.015
epithelial cell migration GO:0010631 148 0.015
Fly
regulation of cellular catabolic process GO:0031329 157 0.015
salivary gland morphogenesis GO:0007435 145 0.015
cell proliferation GO:0008283 299 0.014
Human
cell growth GO:0016049 108 0.014
Human
regulation of response to stress GO:0080134 200 0.014
actin filament organization GO:0007015 126 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
multicellular organism growth GO:0035264 46 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
positive regulation of neurogenesis GO:0050769 41 0.014
positive regulation of axonogenesis GO:0050772 2 0.014
kidney development GO:0001822 3 0.014
regulation of axonogenesis GO:0050770 32 0.014
locomotory behavior GO:0007626 176 0.014
response to alcohol GO:0097305 95 0.014
Human Mouse
gland development GO:0048732 191 0.014
regulation of developmental growth GO:0048638 174 0.014
embryonic pattern specification GO:0009880 174 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
transmembrane transport GO:0055085 139 0.013
synapse assembly GO:0007416 143 0.013
cellular response to abiotic stimulus GO:0071214 58 0.013
Rat
response to insecticide GO:0017085 14 0.013
wound healing GO:0042060 75 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
Human
response to biotic stimulus GO:0009607 294 0.013
Human
cell migration involved in gastrulation GO:0042074 9 0.013
torso signaling pathway GO:0008293 21 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
multicellular organismal aging GO:0010259 140 0.012
positive regulation of developmental growth GO:0048639 62 0.012
compound eye photoreceptor fate commitment GO:0001752 36 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
maintenance of location GO:0051235 73 0.012
regulation of cellular component movement GO:0051270 42 0.012
catabolic process GO:0009056 409 0.012
Mouse
oocyte development GO:0048599 124 0.012
phagocytosis GO:0006909 215 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
Human Rat
homeostatic process GO:0042592 199 0.012
Human Mouse
purine containing compound catabolic process GO:0072523 112 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
regulation of programmed cell death GO:0043067 152 0.012
biological adhesion GO:0022610 138 0.011
regulation of cell differentiation GO:0045595 302 0.011
Human
organonitrogen compound metabolic process GO:1901564 318 0.011
telencephalon development GO:0021537 2 0.011
digestive tract mesoderm development GO:0007502 5 0.011
aromatic compound catabolic process GO:0019439 166 0.011
single organism behavior GO:0044708 391 0.011
regulation of sterol transport GO:0032371 1 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
ras protein signal transduction GO:0007265 88 0.011
trachea development GO:0060438 29 0.011
protein complex biogenesis GO:0070271 201 0.011
Zebrafish
regulation of cellular component biogenesis GO:0044087 201 0.011
Zebrafish
response to external biotic stimulus GO:0043207 293 0.011
Human
salivary gland development GO:0007431 162 0.011
mesoderm formation GO:0001707 21 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
spermatogenesis GO:0007283 200 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
organonitrogen compound catabolic process GO:1901565 128 0.010
gastrulation GO:0007369 70 0.010
detection of chemical stimulus GO:0009593 93 0.010
response to lipid GO:0033993 38 0.010
Human Mouse
cellular protein modification process GO:0006464 438 0.010
endocytosis GO:0006897 310 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
stem cell proliferation GO:0072089 88 0.010
hindgut development GO:0061525 58 0.010
response to nutrient levels GO:0031667 114 0.010
Human Mouse Rat

sad disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
Human
urinary system disease DOID:18 0 0.034