Drosophila melanogaster

61 known processes

MED25 (Dmel_CG12254)

Mediator complex subunit 25

(Aliases: Arc92,dDrip97,Med25,LD07688,Dmel\CG12254,dARC92,med25,CG12254)

MED25 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
snrna 3 end processing GO:0034472 14 0.505
snrna processing GO:0016180 14 0.406
positive regulation of biosynthetic process GO:0009891 316 0.397
Human Mouse
snrna metabolic process GO:0016073 14 0.381
positive regulation of cellular biosynthetic process GO:0031328 316 0.341
Human Mouse
response to external biotic stimulus GO:0043207 293 0.258
positive regulation of rna metabolic process GO:0051254 271 0.223
Human Mouse
nuclear division GO:0000280 332 0.209
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.200
Human Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.184
Human Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.174
Human Mouse
positive regulation of transcription dna templated GO:0045893 266 0.146
Human Mouse
protein complex assembly GO:0006461 200 0.146
Human
positive regulation of gene expression GO:0010628 290 0.144
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.139
Human Mouse
protein complex biogenesis GO:0070271 201 0.132
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.130
Human Mouse
imaginal disc derived appendage development GO:0048737 399 0.118
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.116
Human Mouse
ncrna 3 end processing GO:0043628 17 0.114
actin cytoskeleton organization GO:0030036 206 0.105
establishment or maintenance of cell polarity GO:0007163 167 0.093
organelle fission GO:0048285 340 0.091
positive regulation of multicellular organismal process GO:0051240 143 0.085
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.084
Human Mouse
biological adhesion GO:0022610 138 0.082
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.082
Human
macromolecular complex assembly GO:0065003 256 0.077
Human
immune system process GO:0002376 347 0.077
meiotic nuclear division GO:0007126 151 0.074
internal protein amino acid acetylation GO:0006475 38 0.074
regulation of meiosis GO:0040020 3 0.073
cell adhesion GO:0007155 136 0.069
imaginal disc derived appendage morphogenesis GO:0035114 395 0.065
dna metabolic process GO:0006259 227 0.065
cellular protein modification process GO:0006464 438 0.064
regulation of cell cycle GO:0051726 291 0.063
Human
peptidyl lysine modification GO:0018205 57 0.061
response to organic substance GO:0010033 284 0.060
organonitrogen compound metabolic process GO:1901564 318 0.059
negative regulation of nucleic acid templated transcription GO:1903507 240 0.058
Human
cell proliferation GO:0008283 299 0.057
Human
post embryonic appendage morphogenesis GO:0035120 385 0.056
regulation of immune system process GO:0002682 176 0.056
epithelial cell differentiation GO:0030855 322 0.056
chromosome organization GO:0051276 360 0.056
protein modification process GO:0036211 438 0.055
embryonic pattern specification GO:0009880 174 0.054
histone modification GO:0016570 106 0.053
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.053
Human
regionalization GO:0003002 416 0.052
cell migration GO:0016477 238 0.051
protein acetylation GO:0006473 39 0.051
response to biotic stimulus GO:0009607 294 0.051
epithelium migration GO:0090132 148 0.049
organophosphate metabolic process GO:0019637 195 0.048
appendage morphogenesis GO:0035107 397 0.047
rna polyadenylation GO:0043631 12 0.047
peptidyl lysine acetylation GO:0018394 39 0.047
small molecule metabolic process GO:0044281 305 0.047
protein localization GO:0008104 284 0.045
rna processing GO:0006396 147 0.044
meiotic cell cycle GO:0051321 171 0.043
regulation of cellular component biogenesis GO:0044087 201 0.043
Human
actin filament based process GO:0030029 220 0.043
response to oxygen containing compound GO:1901700 200 0.043
mrna metabolic process GO:0016071 124 0.042
covalent chromatin modification GO:0016569 106 0.041
chromatin organization GO:0006325 207 0.041
response to lipopolysaccharide GO:0032496 4 0.040
appendage development GO:0048736 401 0.040
anterior posterior pattern specification GO:0009952 136 0.040
ncrna metabolic process GO:0034660 43 0.040
protein phosphorylation GO:0006468 169 0.039
intracellular signal transduction GO:0035556 300 0.039
response to other organism GO:0051707 293 0.038
chemotaxis GO:0006935 249 0.038
chromatin modification GO:0016568 147 0.037
regulation of cell proliferation GO:0042127 163 0.036
Human
body morphogenesis GO:0010171 2 0.036
nucleotide metabolic process GO:0009117 161 0.035
wing disc morphogenesis GO:0007472 344 0.035
regulation of multicellular organismal development GO:2000026 414 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.035
Human
regulation of gene expression epigenetic GO:0040029 128 0.035
positive regulation of response to stimulus GO:0048584 323 0.034
dna conformation change GO:0071103 105 0.034
tissue migration GO:0090130 155 0.034
localization of cell GO:0051674 257 0.034
regulation of cell differentiation GO:0045595 302 0.034
muscle structure development GO:0061061 224 0.034
ameboidal type cell migration GO:0001667 151 0.033
regulation of cell cycle process GO:0010564 181 0.033
Human
single organism biosynthetic process GO:0044711 206 0.032
regulation of organelle organization GO:0033043 196 0.031
lateral inhibition GO:0046331 206 0.030
glycosyl compound metabolic process GO:1901657 127 0.029
negative regulation of rna biosynthetic process GO:1902679 240 0.029
Human
defense response GO:0006952 300 0.029
organic substance catabolic process GO:1901575 308 0.029
negative regulation of transcription dna templated GO:0045892 237 0.029
Human
regulation of intracellular signal transduction GO:1902531 236 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
cell motility GO:0048870 251 0.028
catabolic process GO:0009056 409 0.027
negative regulation of signal transduction GO:0009968 206 0.027
negative regulation of signaling GO:0023057 219 0.027
chromatin silencing GO:0006342 76 0.027
negative regulation of biosynthetic process GO:0009890 277 0.027
Human
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
homeostatic process GO:0042592 199 0.027
purine nucleoside catabolic process GO:0006152 112 0.026
regulation of organ morphogenesis GO:2000027 78 0.026
purine containing compound metabolic process GO:0072521 155 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
cellular response to dna damage stimulus GO:0006974 223 0.025
embryo development ending in birth or egg hatching GO:0009792 152 0.025
salivary gland morphogenesis GO:0007435 145 0.025
oocyte development GO:0048599 124 0.024
regulation of multi organism process GO:0043900 131 0.024
aging GO:0007568 143 0.024
nucleoside metabolic process GO:0009116 127 0.024
dendrite development GO:0016358 204 0.024
negative regulation of gene expression GO:0010629 387 0.024
Human
phosphorylation GO:0016310 294 0.024
open tracheal system development GO:0007424 204 0.024
imaginal disc derived leg morphogenesis GO:0007480 80 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
cell division GO:0051301 248 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.023
Human Mouse
ribonucleoside metabolic process GO:0009119 127 0.023
defense response to other organism GO:0098542 225 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.023
Human
negative regulation of cellular metabolic process GO:0031324 382 0.023
Human
locomotory behavior GO:0007626 176 0.023
negative regulation of cell cycle GO:0045786 116 0.023
Human
negative regulation of cell communication GO:0010648 223 0.022
protein acylation GO:0043543 42 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
segmentation GO:0035282 207 0.022
negative regulation of developmental process GO:0051093 201 0.022
single organism behavior GO:0044708 391 0.022
camera type eye development GO:0043010 4 0.022
cellular macromolecule localization GO:0070727 220 0.022
regulation of cell morphogenesis GO:0022604 163 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.022
Human
immune response GO:0006955 246 0.022
notch signaling pathway GO:0007219 120 0.021
muscle cell differentiation GO:0042692 103 0.021
cellular protein localization GO:0034613 160 0.021
histone acetylation GO:0016573 38 0.021
response to heat GO:0009408 63 0.021
determination of adult lifespan GO:0008340 137 0.021
positive regulation of cell communication GO:0010647 250 0.020
single organism cellular localization GO:1902580 180 0.020
neuron projection guidance GO:0097485 241 0.020
vesicle mediated transport GO:0016192 381 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
larval development GO:0002164 104 0.020
leg disc development GO:0035218 92 0.020
tissue morphogenesis GO:0048729 297 0.020
signal transduction by phosphorylation GO:0023014 107 0.020
regulation of localization GO:0032879 275 0.019
taxis GO:0042330 304 0.019
regulation of notch signaling pathway GO:0008593 100 0.019
compound eye development GO:0048749 307 0.019
positive regulation of cellular component organization GO:0051130 156 0.019
Human
purine ribonucleoside metabolic process GO:0046128 127 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
Human Mouse
response to bacterium GO:0009617 198 0.018
gland development GO:0048732 191 0.018
synapse organization GO:0050808 196 0.018
actin filament organization GO:0007015 126 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
single organism catabolic process GO:0044712 228 0.018
regulation of chromatin modification GO:1903308 28 0.018
ncrna processing GO:0034470 30 0.018
positive regulation of immune system process GO:0002684 68 0.018
salivary gland development GO:0007431 162 0.017
stem cell differentiation GO:0048863 117 0.017
regulation of mapk cascade GO:0043408 92 0.017
organic acid metabolic process GO:0006082 103 0.017
cellular response to organic substance GO:0071310 132 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
regulation of chromosome organization GO:0033044 64 0.017
oxoacid metabolic process GO:0043436 103 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
rna 3 end processing GO:0031123 45 0.017
wnt signaling pathway GO:0016055 98 0.017
rna splicing via transesterification reactions GO:0000375 73 0.017
axis specification GO:0009798 167 0.016
purine ribonucleoside catabolic process GO:0046130 112 0.016
positive regulation of signal transduction GO:0009967 223 0.016
mapk cascade GO:0000165 107 0.016
proteolysis GO:0006508 192 0.016
establishment of tissue polarity GO:0007164 87 0.016
gtp metabolic process GO:0046039 72 0.016
autophagy GO:0006914 108 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
Human
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
regulation of protein modification process GO:0031399 112 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
Human
regulation of phosphate metabolic process GO:0019220 210 0.016
positive regulation of cell differentiation GO:0045597 64 0.016
embryonic axis specification GO:0000578 107 0.016
regulation of phosphorylation GO:0042325 147 0.016
cardiovascular system development GO:0072358 82 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.015
exocrine system development GO:0035272 162 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
regulation of cell shape GO:0008360 113 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
regulation of protein metabolic process GO:0051246 256 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
dna templated transcription elongation GO:0006354 18 0.015
multicellular organismal aging GO:0010259 140 0.015
regulation of catalytic activity GO:0050790 185 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
dendrite morphogenesis GO:0048813 199 0.015
organophosphate catabolic process GO:0046434 112 0.014
tube morphogenesis GO:0035239 191 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
chromatin remodeling GO:0006338 72 0.014
regulation of transport GO:0051049 181 0.014
camera type eye morphogenesis GO:0048593 2 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
striated muscle cell differentiation GO:0051146 90 0.014
myotube cell development GO:0014904 3 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
response to nitrogen compound GO:1901698 90 0.014
establishment of localization in cell GO:0051649 402 0.014
axon guidance GO:0007411 233 0.014
purine containing compound catabolic process GO:0072523 112 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
nucleotide catabolic process GO:0009166 109 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
regulation of response to stress GO:0080134 200 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
multi organism behavior GO:0051705 175 0.014
ras protein signal transduction GO:0007265 88 0.013
antimicrobial humoral response GO:0019730 99 0.013
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.013
reproductive system development GO:0061458 74 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
regulation of molecular function GO:0065009 217 0.013
Human
negative regulation of response to stimulus GO:0048585 258 0.013
neurological system process GO:0050877 358 0.013
compound eye morphogenesis GO:0001745 249 0.013
connective tissue development GO:0061448 3 0.013
protein dna complex subunit organization GO:0071824 86 0.013
axon development GO:0061564 297 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
positive regulation of immune response GO:0050778 63 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
dna packaging GO:0006323 91 0.013
positive regulation of mapk cascade GO:0043410 63 0.013
gene silencing GO:0016458 138 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
locomotor rhythm GO:0045475 56 0.013
regulation of chromatin organization GO:1902275 32 0.013
aromatic compound catabolic process GO:0019439 166 0.013
phagocytosis GO:0006909 215 0.013
chromatin assembly or disassembly GO:0006333 52 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
cellular ketone metabolic process GO:0042180 24 0.012
single organism cell adhesion GO:0098602 47 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
regulation of cell division GO:0051302 72 0.012
positive regulation of developmental process GO:0051094 143 0.012
positive regulation of growth GO:0045927 75 0.012
eye morphogenesis GO:0048592 260 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
epidermis development GO:0008544 65 0.012
retina morphogenesis in camera type eye GO:0060042 2 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
signal transduction in response to dna damage GO:0042770 3 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
regulation of immune response GO:0050776 118 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
retina development in camera type eye GO:0060041 4 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.011
protein transport GO:0015031 155 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
stem cell development GO:0048864 79 0.011
endocytosis GO:0006897 310 0.011
humoral immune response GO:0006959 117 0.011
tube development GO:0035295 244 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
eye development GO:0001654 323 0.011
amine metabolic process GO:0009308 12 0.011
regulation of response to external stimulus GO:0032101 115 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
ovarian nurse cell to oocyte transport GO:0007300 27 0.011
oocyte differentiation GO:0009994 145 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
ovarian follicle cell migration GO:0007297 121 0.011
morphogenesis of a polarized epithelium GO:0001738 93 0.011
cellular amine metabolic process GO:0044106 12 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
sensory organ morphogenesis GO:0090596 260 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
positive regulation of signaling GO:0023056 243 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.010
respiratory system development GO:0060541 213 0.010
mrna processing GO:0006397 104 0.010
protein dna complex assembly GO:0065004 63 0.010
regulation of gene silencing GO:0060968 63 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010

MED25 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
Human
nervous system disease DOID:863 0 0.014
Human