Drosophila melanogaster

26 known processes

Or98a (Dmel_CG5540)

Odorant receptor 98a

(Aliases: 98B.1,CG5540,98a,DOR110,Dmel\CG5540)

Or98a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of chemical stimulus GO:0009593 93 0.109
detection of stimulus involved in sensory perception GO:0050906 92 0.069
neurological system process GO:0050877 358 0.060
sensory perception of chemical stimulus GO:0007606 116 0.060
detection of stimulus GO:0051606 156 0.054
sensory perception GO:0007600 196 0.051
detection of chemical stimulus involved in sensory perception of smell GO:0050911 50 0.046
organonitrogen compound metabolic process GO:1901564 318 0.043
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.043
sensory perception of smell GO:0007608 80 0.043
single organism behavior GO:0044708 391 0.042
Fly
response to abiotic stimulus GO:0009628 341 0.041
response to oxygen containing compound GO:1901700 200 0.039
protein modification process GO:0036211 438 0.038
small molecule metabolic process GO:0044281 305 0.037
epithelial cell development GO:0002064 274 0.035
response to organic substance GO:0010033 284 0.034
cellular protein modification process GO:0006464 438 0.032
positive regulation of cell communication GO:0010647 250 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.032
organelle fission GO:0048285 340 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
regulation of localization GO:0032879 275 0.031
catabolic process GO:0009056 409 0.030
vesicle mediated transport GO:0016192 381 0.030
response to lipopolysaccharide GO:0032496 4 0.030
transcription from rna polymerase ii promoter GO:0006366 368 0.030
positive regulation of signaling GO:0023056 243 0.030
organic acid metabolic process GO:0006082 103 0.030
oxoacid metabolic process GO:0043436 103 0.029
response to biotic stimulus GO:0009607 294 0.029
organic substance catabolic process GO:1901575 308 0.029
regulation of multicellular organismal development GO:2000026 414 0.029
forebrain development GO:0030900 2 0.029
cellular catabolic process GO:0044248 372 0.028
nuclear division GO:0000280 332 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.028
regionalization GO:0003002 416 0.028
positive regulation of signal transduction GO:0009967 223 0.027
response to external biotic stimulus GO:0043207 293 0.027
carboxylic acid metabolic process GO:0019752 92 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.027
cell migration GO:0016477 238 0.027
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.027
defense response GO:0006952 300 0.027
negative regulation of gene expression GO:0010629 387 0.027
endocytosis GO:0006897 310 0.027
positive regulation of nucleic acid templated transcription GO:1903508 266 0.027
positive regulation of biosynthetic process GO:0009891 316 0.027
cell death GO:0008219 279 0.027
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
epithelial cell differentiation GO:0030855 322 0.026
organic substance transport GO:0071702 257 0.026
response to other organism GO:0051707 293 0.026
localization of cell GO:0051674 257 0.025
homeostatic process GO:0042592 199 0.025
positive regulation of cellular biosynthetic process GO:0031328 316 0.025
negative regulation of response to stimulus GO:0048585 258 0.024
columnar cuboidal epithelial cell development GO:0002066 249 0.024
single organism biosynthetic process GO:0044711 206 0.024
establishment of localization in cell GO:0051649 402 0.024
regulation of cellular component biogenesis GO:0044087 201 0.024
body morphogenesis GO:0010171 2 0.024
cellular amino acid metabolic process GO:0006520 61 0.024
regulation of cell cycle GO:0051726 291 0.024
immune system process GO:0002376 347 0.024
wing disc morphogenesis GO:0007472 344 0.024
imaginal disc derived appendage development GO:0048737 399 0.023
phosphorylation GO:0016310 294 0.023
phagocytosis GO:0006909 215 0.023
telencephalon development GO:0021537 2 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.023
regulation of organelle organization GO:0033043 196 0.023
kidney development GO:0001822 3 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
post embryonic appendage morphogenesis GO:0035120 385 0.023
regulation of protein metabolic process GO:0051246 256 0.023
protein localization GO:0008104 284 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
cell motility GO:0048870 251 0.022
death GO:0016265 284 0.022
cell division GO:0051301 248 0.022
single organism catabolic process GO:0044712 228 0.022
programmed cell death GO:0012501 257 0.022
organophosphate metabolic process GO:0019637 195 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.022
response to organophosphorus GO:0046683 2 0.022
camera type eye development GO:0043010 4 0.022
axonogenesis GO:0007409 290 0.022
regulation of molecular function GO:0065009 217 0.021
taxis GO:0042330 304 0.021
positive regulation of gene expression GO:0010628 290 0.021
positive regulation of transcription dna templated GO:0045893 266 0.021
intracellular signal transduction GO:0035556 300 0.021
macromolecular complex assembly GO:0065003 256 0.021
compound eye development GO:0048749 307 0.021
appendage development GO:0048736 401 0.021
gland development GO:0048732 191 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
regulation of synapse structure and activity GO:0050803 128 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
response to bacterium GO:0009617 198 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
developmental growth GO:0048589 280 0.020
mitotic nuclear division GO:0007067 213 0.020
developmental maturation GO:0021700 172 0.020
regulation of mitotic cell cycle GO:0007346 190 0.020
negative regulation of cell communication GO:0010648 223 0.020
regulation of cell death GO:0010941 173 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
regulation of cellular protein metabolic process GO:0032268 243 0.020
mating GO:0007618 120 0.020
gland morphogenesis GO:0022612 145 0.020
appendage morphogenesis GO:0035107 397 0.020
regulation of nervous system development GO:0051960 248 0.019
ovarian follicle cell development GO:0030707 248 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
amine metabolic process GO:0009308 12 0.019
proteolysis GO:0006508 192 0.019
protein complex assembly GO:0006461 200 0.019
lateral inhibition GO:0046331 206 0.019
Fly
protein heterooligomerization GO:0051291 4 0.019
regulation of catalytic activity GO:0050790 185 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
segmentation GO:0035282 207 0.019
chemotaxis GO:0006935 249 0.019
response to alcohol GO:0097305 95 0.018
nucleotide metabolic process GO:0009117 161 0.018
g protein coupled receptor signaling pathway GO:0007186 136 0.018
positive regulation of cell migration GO:0030335 2 0.018
salivary gland development GO:0007431 162 0.018
cell proliferation GO:0008283 299 0.018
connective tissue development GO:0061448 3 0.018
positive regulation of cell motility GO:2000147 3 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
Fly
negative regulation of signal transduction GO:0009968 206 0.018
benzene containing compound metabolic process GO:0042537 3 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
defense response to other organism GO:0098542 225 0.018
negative regulation of signaling GO:0023057 219 0.018
protein complex biogenesis GO:0070271 201 0.018
growth GO:0040007 359 0.018
monocarboxylic acid transport GO:0015718 3 0.018
regulation of response to stress GO:0080134 200 0.018
regulation of cell cycle process GO:0010564 181 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
regulation of transport GO:0051049 181 0.017
salivary gland morphogenesis GO:0007435 145 0.017
cellular amine metabolic process GO:0044106 12 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
open tracheal system development GO:0007424 204 0.017
respiratory system development GO:0060541 213 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
regulation of anatomical structure size GO:0090066 163 0.017
eye development GO:0001654 323 0.017
endomembrane system organization GO:0010256 119 0.017
regulation of immune system process GO:0002682 176 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
steroid catabolic process GO:0006706 1 0.017
hormone catabolic process GO:0042447 3 0.017
exocrine system development GO:0035272 162 0.017
synaptic transmission GO:0007268 288 0.016
xenobiotic catabolic process GO:0042178 1 0.016
blastoderm segmentation GO:0007350 159 0.016
tissue morphogenesis GO:0048729 297 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
response to temperature stimulus GO:0009266 106 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
regulation of developmental growth GO:0048638 174 0.016
adult behavior GO:0030534 137 0.016
negative regulation of developmental process GO:0051093 201 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
peptide metabolic process GO:0006518 80 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
cellular ketone metabolic process GO:0042180 24 0.016
regulation of cell differentiation GO:0045595 302 0.016
intracellular transport GO:0046907 228 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
lipid metabolic process GO:0006629 121 0.016
retina development in camera type eye GO:0060041 4 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.015
sterol homeostasis GO:0055092 4 0.015
response to wounding GO:0009611 94 0.015
aging GO:0007568 143 0.015
hindbrain development GO:0030902 2 0.015
heterocycle catabolic process GO:0046700 166 0.015
regulation of programmed cell death GO:0043067 152 0.015
locomotory behavior GO:0007626 176 0.015
purine containing compound metabolic process GO:0072521 155 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
chromosome organization GO:0051276 360 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
multi multicellular organism process GO:0044706 123 0.015
organelle assembly GO:0070925 198 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
response to endogenous stimulus GO:0009719 119 0.015
establishment of protein localization GO:0045184 163 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
regulation of growth GO:0040008 233 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.015
embryonic pattern specification GO:0009880 174 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
immune response activating signal transduction GO:0002757 2 0.015
secretion GO:0046903 109 0.015
secretion by cell GO:0032940 101 0.015
regulation of cellular localization GO:0060341 136 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
compound eye morphogenesis GO:0001745 249 0.015
aromatic compound catabolic process GO:0019439 166 0.015
spinal cord development GO:0021510 1 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
mating behavior GO:0007617 106 0.015
regulation of immune response GO:0050776 118 0.015
ras protein signal transduction GO:0007265 88 0.015
response to radiation GO:0009314 155 0.015
regulation of multi organism process GO:0043900 131 0.015
regulation of response to external stimulus GO:0032101 115 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
axon development GO:0061564 297 0.014
actin cytoskeleton organization GO:0030036 206 0.014
multi organism behavior GO:0051705 175 0.014
protein transport GO:0015031 155 0.014
protein phosphorylation GO:0006468 169 0.014
rhythmic process GO:0048511 106 0.014
cognition GO:0050890 141 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
pigmentation GO:0043473 75 0.014
anion homeostasis GO:0055081 3 0.014
apoptotic process GO:0006915 159 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
macromolecule catabolic process GO:0009057 161 0.014
estrogen metabolic process GO:0008210 1 0.014
sensory organ morphogenesis GO:0090596 260 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
spindle organization GO:0007051 253 0.014
response to nitrogen compound GO:1901698 90 0.014
synapse organization GO:0050808 196 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
response to extracellular stimulus GO:0009991 116 0.014
dendrite development GO:0016358 204 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
multicellular organismal aging GO:0010259 140 0.014
cholesterol homeostasis GO:0042632 3 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
olfactory behavior GO:0042048 97 0.014
Fly
morphogenesis of an epithelium GO:0002009 276 0.014
immune response GO:0006955 246 0.013
single organism cellular localization GO:1902580 180 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
drinking behavior GO:0042756 2 0.013
regulation of apoptotic process GO:0042981 130 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
androgen metabolic process GO:0008209 1 0.013
tube morphogenesis GO:0035239 191 0.013
actin filament based process GO:0030029 220 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
regulation of catabolic process GO:0009894 170 0.013
developmental programmed cell death GO:0010623 138 0.013
cellular macromolecule localization GO:0070727 220 0.013
response to nutrient levels GO:0031667 114 0.013
response to copper ion GO:0046688 4 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
single organism intracellular transport GO:1902582 207 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
adult locomotory behavior GO:0008344 76 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
regulation of phosphorylation GO:0042325 147 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
cellular response to ethanol GO:0071361 4 0.013
central nervous system development GO:0007417 201 0.013
regulation of behavior GO:0050795 75 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
male gamete generation GO:0048232 201 0.013
regulation of mapk cascade GO:0043408 92 0.013
gene silencing GO:0016458 138 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
defense response to bacterium GO:0042742 178 0.013
camera type eye morphogenesis GO:0048593 2 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
response to organonitrogen compound GO:0010243 75 0.013
spermatogenesis GO:0007283 200 0.013
chemosensory behavior GO:0007635 106 0.013
Fly
membrane organization GO:0061024 112 0.013
eye morphogenesis GO:0048592 260 0.013
positive regulation of molecular function GO:0044093 136 0.013
nephron development GO:0072006 3 0.013
sensory perception of salty taste GO:0050914 3 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
regulation of hydrolase activity GO:0051336 97 0.012
salivary gland histolysis GO:0035070 88 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
chaeta development GO:0022416 97 0.012
innate immune response GO:0045087 144 0.012
response to organic cyclic compound GO:0014070 89 0.012
neuron projection guidance GO:0097485 241 0.012
ameboidal type cell migration GO:0001667 151 0.012
axis specification GO:0009798 167 0.012
wnt signaling pathway GO:0016055 98 0.012
cellular lipid metabolic process GO:0044255 83 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
response to light stimulus GO:0009416 124 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
mapk cascade GO:0000165 107 0.012
ion transport GO:0006811 145 0.012
actin filament organization GO:0007015 126 0.012
digestive tract development GO:0048565 149 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
acetate ester metabolic process GO:1900619 2 0.012
behavioral response to pain GO:0048266 3 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
determination of adult lifespan GO:0008340 137 0.012
embryonic morphogenesis GO:0048598 206 0.012
protein maturation GO:0051604 71 0.012
response to monosaccharide GO:0034284 4 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
negative regulation of nervous system development GO:0051961 92 0.012
regulation of cell development GO:0060284 215 0.012
neuropeptide signaling pathway GO:0007218 45 0.012
cell cycle phase transition GO:0044770 140 0.012
cellular homeostasis GO:0019725 80 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
aggressive behavior GO:0002118 63 0.012
organophosphate catabolic process GO:0046434 112 0.012
chemical homeostasis GO:0048878 92 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
synaptic growth at neuromuscular junction GO:0051124 119 0.011
chromosome segregation GO:0007059 157 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
pigment metabolic process GO:0042440 84 0.011
immune effector process GO:0002252 98 0.011
protein dna complex subunit organization GO:0071824 86 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
mesoderm development GO:0007498 78 0.011
learning or memory GO:0007611 141 0.011
regulation of cell projection organization GO:0031344 92 0.011
rhythmic behavior GO:0007622 76 0.011
regulation of synaptic transmission GO:0050804 69 0.011
notch signaling pathway GO:0007219 120 0.011
peptidyl amino acid modification GO:0018193 105 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
pattern recognition receptor signaling pathway GO:0002221 2 0.011
oocyte differentiation GO:0009994 145 0.011
male mating behavior GO:0060179 70 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
rna localization GO:0006403 115 0.011
sensory perception of pain GO:0019233 4 0.011
secondary metabolic process GO:0019748 75 0.011
cell projection assembly GO:0030031 94 0.011
inter male aggressive behavior GO:0002121 60 0.011
meiotic nuclear division GO:0007126 151 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
antimicrobial humoral response GO:0019730 99 0.011
wound healing GO:0042060 75 0.011
insecticide metabolic process GO:0017143 2 0.011
neurotransmitter metabolic process GO:0042133 2 0.011
chromatin modification GO:0016568 147 0.011
regulation of synapse assembly GO:0051963 94 0.011
chromatin remodeling GO:0006338 72 0.011
nephron epithelium development GO:0072009 3 0.011
regulation of cell shape GO:0008360 113 0.011
regulation of synapse organization GO:0050807 110 0.011
biological adhesion GO:0022610 138 0.011
digestive tract morphogenesis GO:0048546 127 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
activation of innate immune response GO:0002218 4 0.011
sulfur compound metabolic process GO:0006790 59 0.011
eggshell formation GO:0030703 105 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
fat soluble vitamin metabolic process GO:0006775 1 0.011
positive regulation of developmental process GO:0051094 143 0.011
response to glucose GO:0009749 2 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
positive regulation of catabolic process GO:0009896 105 0.011
limb development GO:0060173 1 0.011
axon guidance GO:0007411 233 0.011
cellular protein localization GO:0034613 160 0.011
peptide biosynthetic process GO:0043043 42 0.011
membrane depolarization GO:0051899 4 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
cellular response to organic substance GO:0071310 132 0.010
digestive system development GO:0055123 149 0.010
synapse assembly GO:0007416 143 0.010
protein processing GO:0016485 68 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
response to hexose GO:0009746 3 0.010
rna processing GO:0006396 147 0.010
cytoplasmic transport GO:0016482 130 0.010
photoreceptor cell differentiation GO:0046530 170 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
cation transmembrane transport GO:0098655 88 0.010
tissue death GO:0016271 102 0.010
positive regulation of transport GO:0051050 92 0.010
dephosphorylation GO:0016311 51 0.010
developmental pigmentation GO:0048066 68 0.010
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
l amino acid import GO:0043092 2 0.010
golgi organization GO:0007030 66 0.010
cation transport GO:0006812 110 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010
regulation of cellular component size GO:0032535 98 0.010
vitamin metabolic process GO:0006766 2 0.010
meiotic cell cycle GO:0051321 171 0.010
regulation of protein modification process GO:0031399 112 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
fat soluble vitamin biosynthetic process GO:0042362 1 0.010
anterior posterior pattern specification GO:0009952 136 0.010
amide biosynthetic process GO:0043604 42 0.010
salt aversion GO:0035199 3 0.010
polyol biosynthetic process GO:0046173 3 0.010
endodermal cell differentiation GO:0035987 3 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
dorsal ventral axis specification GO:0009950 66 0.010
kidney morphogenesis GO:0060993 3 0.010
transmembrane transport GO:0055085 139 0.010
single organism membrane organization GO:0044802 93 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
cytokinesis GO:0000910 90 0.010
tube development GO:0035295 244 0.010

Or98a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.017
renal tubular transport disease DOID:447 0 0.017
kidney disease DOID:557 0 0.017
urinary system disease DOID:18 0 0.017
cardiovascular system disease DOID:1287 0 0.016
inherited metabolic disorder DOID:655 0 0.014
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
musculoskeletal system disease DOID:17 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
acquired metabolic disease DOID:0060158 0 0.010
central nervous system disease DOID:331 0 0.010