Drosophila melanogaster

194 known processes

rdx (Dmel_CG12537)

roadkill

(Aliases: anon-WO0118547.577,CG9924,CG12537,Spop,Dromel_CG9924_FBtr0082871_rdx_mORF,hib,Rdx,CG10235,BEST:GM07940,Dmel_CG9924,D-SPOP,Dmel\CG12537)

rdx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of protein metabolic process GO:0051246 256 0.873
appendage morphogenesis GO:0035107 397 0.748
negative regulation of gene expression GO:0010629 387 0.659
regulation of cell differentiation GO:0045595 302 0.644
negative regulation of nucleic acid templated transcription GO:1903507 240 0.619
positive regulation of response to stimulus GO:0048584 323 0.595
circulatory system development GO:0072359 82 0.577
growth GO:0040007 359 0.562
negative regulation of biosynthetic process GO:0009890 277 0.558
wing disc morphogenesis GO:0007472 344 0.545
columnar cuboidal epithelial cell development GO:0002066 249 0.491
compound eye development GO:0048749 307 0.484
positive regulation of macromolecule metabolic process GO:0010604 405 0.471
catabolic process GO:0009056 409 0.457
Human
apoptotic process GO:0006915 159 0.426
regulation of programmed cell death GO:0043067 152 0.425
regulation of cell development GO:0060284 215 0.422
cellular protein modification process GO:0006464 438 0.411
regulation of cellular protein metabolic process GO:0032268 243 0.406
Human
establishment of localization in cell GO:0051649 402 0.392
chromosome organization GO:0051276 360 0.342
nuclear division GO:0000280 332 0.341
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.331
imaginal disc derived wing morphogenesis GO:0007476 337 0.314
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.299
imaginal disc derived appendage morphogenesis GO:0035114 395 0.295
dendrite development GO:0016358 204 0.284
organelle fission GO:0048285 340 0.277
chromatin organization GO:0006325 207 0.271
regulation of multicellular organismal development GO:2000026 414 0.265
meiotic cell cycle process GO:1903046 132 0.263
positive regulation of wnt signaling pathway GO:0030177 25 0.262
negative regulation of rna biosynthetic process GO:1902679 240 0.262
protein modification process GO:0036211 438 0.258
positive regulation of signaling GO:0023056 243 0.244
regulation of organelle organization GO:0033043 196 0.241
post embryonic appendage morphogenesis GO:0035120 385 0.238
cell proliferation GO:0008283 299 0.227
appendage development GO:0048736 401 0.210
memory GO:0007613 94 0.209
chromosome condensation GO:0030261 41 0.208
positive regulation of cell communication GO:0010647 250 0.208
dendrite morphogenesis GO:0048813 199 0.202
developmental growth GO:0048589 280 0.190
regulation of wnt signaling pathway GO:0030111 68 0.188
negative regulation of mitotic cell cycle GO:0045930 109 0.182
establishment or maintenance of cell polarity GO:0007163 167 0.175
regulation of mitotic cell cycle GO:0007346 190 0.164
protein transport GO:0015031 155 0.160
male gamete generation GO:0048232 201 0.160
negative regulation of cell cycle phase transition GO:1901988 103 0.157
single organism cellular localization GO:1902580 180 0.156
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.154
organic substance catabolic process GO:1901575 308 0.153
Human
eye morphogenesis GO:0048592 260 0.153
regulation of cell cycle GO:0051726 291 0.151
gliogenesis GO:0042063 80 0.150
negative regulation of cell cycle GO:0045786 116 0.149
compound eye morphogenesis GO:0001745 249 0.148
histolysis GO:0007559 102 0.147
regionalization GO:0003002 416 0.147
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.146
sensory organ morphogenesis GO:0090596 260 0.145
chromatin remodeling GO:0006338 72 0.144
regulation of nervous system development GO:0051960 248 0.138
positive regulation of transcription dna templated GO:0045893 266 0.138
sister chromatid segregation GO:0000819 92 0.134
tissue morphogenesis GO:0048729 297 0.131
dephosphorylation GO:0016311 51 0.129
regulation of cell cycle phase transition GO:1901987 130 0.127
epithelial cell differentiation GO:0030855 322 0.121
posttranscriptional regulation of gene expression GO:0010608 145 0.120
regulation of neurogenesis GO:0050767 158 0.120
regulation of transport GO:0051049 181 0.119
regulation of cell cycle process GO:0010564 181 0.118
programmed cell death GO:0012501 257 0.118
positive regulation of signal transduction GO:0009967 223 0.116
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.114
positive regulation of developmental process GO:0051094 143 0.110
negative regulation of cellular biosynthetic process GO:0031327 277 0.106
dna packaging GO:0006323 91 0.103
locomotory behavior GO:0007626 176 0.103
g2 dna damage checkpoint GO:0031572 69 0.102
central nervous system development GO:0007417 201 0.100
chromatin modification GO:0016568 147 0.099
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.098
ovarian follicle cell development GO:0030707 248 0.095
spermatogenesis GO:0007283 200 0.094
positive regulation of cellular protein metabolic process GO:0032270 118 0.091
mitotic dna integrity checkpoint GO:0044774 75 0.090
response to organic substance GO:0010033 284 0.089
neuronal stem cell division GO:0036445 35 0.088
mitotic g2 m transition checkpoint GO:0044818 70 0.087
chromosome segregation GO:0007059 157 0.084
negative regulation of cellular metabolic process GO:0031324 382 0.084
Human
macromolecular complex assembly GO:0065003 256 0.084
tissue death GO:0016271 102 0.082
exocrine system development GO:0035272 162 0.082
positive regulation of multicellular organismal process GO:0051240 143 0.081
dna damage checkpoint GO:0000077 78 0.081
organic substance transport GO:0071702 257 0.080
muscle structure development GO:0061061 224 0.080
mitotic g2 dna damage checkpoint GO:0007095 69 0.079
protein complex assembly GO:0006461 200 0.075
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.074
cellular response to chemical stimulus GO:0070887 199 0.073
intracellular signal transduction GO:0035556 300 0.073
dna metabolic process GO:0006259 227 0.072
cell cycle checkpoint GO:0000075 95 0.072
endomembrane system organization GO:0010256 119 0.071
cell junction assembly GO:0034329 42 0.071
negative regulation of transcription dna templated GO:0045892 237 0.071
multicellular organismal aging GO:0010259 140 0.070
secretion GO:0046903 109 0.068
epithelial cell development GO:0002064 274 0.064
mitotic cell cycle checkpoint GO:0007093 88 0.063
positive regulation of programmed cell death GO:0043068 62 0.062
regulation of developmental growth GO:0048638 174 0.060
embryo development ending in birth or egg hatching GO:0009792 152 0.057
regulation of cell morphogenesis GO:0022604 163 0.057
imaginal disc derived appendage development GO:0048737 399 0.057
regulation of molecular function GO:0065009 217 0.055
salivary gland development GO:0007431 162 0.055
stem cell division GO:0017145 69 0.055
cellular response to dna damage stimulus GO:0006974 223 0.054
mitotic cell cycle phase transition GO:0044772 138 0.052
mitotic nuclear division GO:0007067 213 0.051
positive regulation of molecular function GO:0044093 136 0.051
olfactory behavior GO:0042048 97 0.051
wnt signaling pathway GO:0016055 98 0.050
regulation of intracellular signal transduction GO:1902531 236 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.048
microtubule organizing center organization GO:0031023 168 0.048
translation GO:0006412 69 0.045
rna interference GO:0016246 27 0.044
eggshell formation GO:0030703 105 0.044
cellular response to oxygen levels GO:0071453 30 0.043
negative regulation of cell communication GO:0010648 223 0.043
eye development GO:0001654 323 0.042
salivary gland cell autophagic cell death GO:0035071 83 0.042
histone h4 acetylation GO:0043967 13 0.042
positive regulation of rna metabolic process GO:0051254 271 0.041
dna integrity checkpoint GO:0031570 81 0.041
transcription from rna polymerase ii promoter GO:0006366 368 0.041
positive regulation of phosphorus metabolic process GO:0010562 139 0.041
long term memory GO:0007616 62 0.040
centrosome organization GO:0051297 163 0.040
regulation of dendrite morphogenesis GO:0048814 28 0.040
negative regulation of cell cycle process GO:0010948 109 0.040
positive regulation of catalytic activity GO:0043085 118 0.040
positive regulation of protein metabolic process GO:0051247 128 0.040
morphogenesis of follicular epithelium GO:0016333 36 0.040
endocytosis GO:0006897 310 0.039
spermatid differentiation GO:0048515 114 0.038
imaginal disc fusion GO:0046528 19 0.037
notch signaling pathway GO:0007219 120 0.036
head development GO:0060322 135 0.036
heterocycle catabolic process GO:0046700 166 0.036
rna splicing GO:0008380 83 0.036
negative regulation of cell proliferation GO:0008285 69 0.036
single organism catabolic process GO:0044712 228 0.035
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.035
rna localization GO:0006403 115 0.035
rhythmic process GO:0048511 106 0.035
apposition of dorsal and ventral imaginal disc derived wing surfaces GO:0007475 15 0.035
positive regulation of phosphate metabolic process GO:0045937 139 0.034
regulation of cell proliferation GO:0042127 163 0.034
negative regulation of organelle organization GO:0010639 56 0.034
cellular macromolecule catabolic process GO:0044265 136 0.033
Human
cytokinesis GO:0000910 90 0.033
vesicle mediated transport GO:0016192 381 0.032
regulation of translation GO:0006417 56 0.032
regulation of rna splicing GO:0043484 69 0.032
muscle organ development GO:0007517 127 0.032
secretion by cell GO:0032940 101 0.032
regulation of transferase activity GO:0051338 58 0.032
meiotic nuclear division GO:0007126 151 0.031
stem cell development GO:0048864 79 0.031
aromatic compound catabolic process GO:0019439 166 0.031
gland development GO:0048732 191 0.031
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.031
humoral immune response GO:0006959 117 0.030
negative regulation of translation GO:0017148 28 0.030
photoreceptor cell differentiation GO:0046530 170 0.030
intercellular bridge organization GO:0043063 14 0.030
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.029
forebrain development GO:0030900 2 0.029
cell division GO:0051301 248 0.028
autophagic cell death GO:0048102 83 0.028
small molecule metabolic process GO:0044281 305 0.028
posttranscriptional gene silencing by rna GO:0035194 45 0.028
cell cycle phase transition GO:0044770 140 0.028
positive regulation of growth GO:0045927 75 0.028
death GO:0016265 284 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
regulation of malpighian tubule diameter GO:0035297 3 0.026
mitotic sister chromatid segregation GO:0000070 87 0.025
mitotic dna damage checkpoint GO:0044773 74 0.025
generation of precursor metabolites and energy GO:0006091 42 0.025
regulation of dendrite development GO:0050773 37 0.025
cellular catabolic process GO:0044248 372 0.024
Human
regulation of actin cytoskeleton organization GO:0032956 42 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.024
positive regulation of cell death GO:0010942 69 0.024
regulation of neuron differentiation GO:0045664 103 0.023
mrna processing GO:0006397 104 0.023
protein phosphorylation GO:0006468 169 0.023
positive regulation of nervous system development GO:0051962 69 0.022
regulation of defense response GO:0031347 102 0.022
cognition GO:0050890 141 0.022
golgi organization GO:0007030 66 0.021
regulation of proteolysis GO:0030162 87 0.021
mitotic cell cycle embryonic GO:0045448 38 0.021
mrna metabolic process GO:0016071 124 0.021
nuclear transport GO:0051169 72 0.021
germline ring canal formation GO:0030725 13 0.021
cell death GO:0008219 279 0.021
developmental maturation GO:0021700 172 0.021
regulation of catalytic activity GO:0050790 185 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
chemosensory behavior GO:0007635 106 0.020
protein localization GO:0008104 284 0.020
brain development GO:0007420 120 0.020
organic acid metabolic process GO:0006082 103 0.020
positive regulation of cell development GO:0010720 61 0.020
chromosome separation GO:0051304 42 0.019
regulation of synapse structure and activity GO:0050803 128 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
heart development GO:0007507 82 0.019
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.018
mitotic spindle organization GO:0007052 220 0.018
spermatid development GO:0007286 98 0.018
chitin based cuticle development GO:0040003 49 0.018
protein complex biogenesis GO:0070271 201 0.018
antimicrobial humoral response GO:0019730 99 0.018
cardiovascular system development GO:0072358 82 0.017
developmental programmed cell death GO:0010623 138 0.017
nucleus localization GO:0051647 34 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
extrinsic apoptotic signaling pathway GO:0097191 1 0.017
nucleotide catabolic process GO:0009166 109 0.017
positive regulation of developmental growth GO:0048639 62 0.016
signal release GO:0023061 49 0.016
neuroblast division GO:0055057 35 0.016
immune response GO:0006955 246 0.016
regulation of cell size GO:0008361 63 0.016
oocyte maturation GO:0001556 3 0.016
meiotic chromosome segregation GO:0045132 59 0.016
negative regulation of developmental process GO:0051093 201 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
macromolecule catabolic process GO:0009057 161 0.015
Human
regulation of cellular localization GO:0060341 136 0.015
regulation of mitotic sister chromatid segregation GO:0033047 28 0.015
sex differentiation GO:0007548 81 0.015
positive regulation of transport GO:0051050 92 0.015
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.015
single organism behavior GO:0044708 391 0.015
nucleocytoplasmic transport GO:0006913 72 0.015
instar larval development GO:0002168 55 0.014
positive regulation of neurogenesis GO:0050769 41 0.014
segmentation GO:0035282 207 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
oocyte development GO:0048599 124 0.014
salivary gland histolysis GO:0035070 88 0.014
regulation of meiosis GO:0040020 3 0.014
organ growth GO:0035265 56 0.014
larval development GO:0002164 104 0.013
positive regulation of protein kinase activity GO:0045860 25 0.013
regulation of protein modification process GO:0031399 112 0.013
Human
oocyte differentiation GO:0009994 145 0.013
phagocytosis GO:0006909 215 0.013
positive regulation of transferase activity GO:0051347 26 0.013
rna catabolic process GO:0006401 37 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
positive regulation of gene expression GO:0010628 290 0.013
positive regulation of catabolic process GO:0009896 105 0.013
regulation of hydrolase activity GO:0051336 97 0.012
positive regulation of cell cycle process GO:0090068 28 0.012
cellular macromolecule localization GO:0070727 220 0.012
carbohydrate metabolic process GO:0005975 82 0.012
regulation of muscle organ development GO:0048634 13 0.012
cuticle development GO:0042335 86 0.012
respiratory system development GO:0060541 213 0.012
immune system process GO:0002376 347 0.012
posttranscriptional gene silencing GO:0016441 46 0.012
aging GO:0007568 143 0.012
positive regulation of r7 cell differentiation GO:0045678 7 0.012
rhythmic behavior GO:0007622 76 0.012
chaeta development GO:0022416 97 0.012
negative regulation of cell differentiation GO:0045596 143 0.011
negative regulation of neuron apoptotic process GO:0043524 14 0.011
receptor clustering GO:0043113 3 0.011
covalent chromatin modification GO:0016569 106 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
positive regulation of protein modification process GO:0031401 58 0.011
mrna splicing via spliceosome GO:0000398 73 0.011
regulation of mrna splicing via spliceosome GO:0048024 64 0.011
actin filament organization GO:0007015 126 0.011
histone h3 acetylation GO:0043966 11 0.011
blastoderm segmentation GO:0007350 159 0.011
regulation of eye photoreceptor cell development GO:0042478 13 0.011
regulation of immune response GO:0050776 118 0.011
response to oxidative stress GO:0006979 86 0.011
muscle tissue development GO:0060537 30 0.011
positive regulation of immune response GO:0050778 63 0.011
morphogenesis of an epithelium GO:0002009 276 0.010
regulation of protein localization GO:0032880 76 0.010
negative regulation of organ growth GO:0046621 15 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
regulation of kinase activity GO:0043549 53 0.010
regulation of cytoplasmic transport GO:1903649 47 0.010
regulation of sister chromatid segregation GO:0033045 28 0.010
negative regulation of intracellular signal transduction GO:1902532 57 0.010
neuroblast proliferation GO:0007405 74 0.010
body morphogenesis GO:0010171 2 0.010
synaptic transmission GO:0007268 288 0.010
regulation of cell shape GO:0008360 113 0.010

rdx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org