Drosophila melanogaster

0 known processes

miple (Dmel_CG1221)

CG1221 gene product from transcript CG1221-RA

(Aliases: miple1,Miple,Dmel\CG1221,CG1221,anon-EST:Posey203)

miple biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization in cell GO:0051649 402 0.171
tissue morphogenesis GO:0048729 297 0.133
neurological system process GO:0050877 358 0.120
positive regulation of cgmp metabolic process GO:0030825 1 0.119
kidney development GO:0001822 3 0.096
cgmp biosynthetic process GO:0006182 8 0.094
single organism intracellular transport GO:1902582 207 0.078
positive regulation of cgmp biosynthetic process GO:0030828 1 0.077
actin cytoskeleton organization GO:0030036 206 0.076
intracellular signal transduction GO:0035556 300 0.074
sensory perception GO:0007600 196 0.073
biological adhesion GO:0022610 138 0.071
appendage development GO:0048736 401 0.069
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.068
response to abiotic stimulus GO:0009628 341 0.065
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.064
positive regulation of response to stimulus GO:0048584 323 0.064
regulation of cell cycle GO:0051726 291 0.063
negative regulation of response to stimulus GO:0048585 258 0.062
intracellular transport GO:0046907 228 0.062
cell adhesion GO:0007155 136 0.061
morphogenesis of an epithelium GO:0002009 276 0.060
nucleocytoplasmic transport GO:0006913 72 0.059
positive regulation of lyase activity GO:0051349 10 0.058
muscle cell differentiation GO:0042692 103 0.057
muscle structure development GO:0061061 224 0.056
programmed cell death GO:0012501 257 0.056
organelle assembly GO:0070925 198 0.056
cellular macromolecular complex assembly GO:0034622 153 0.053
cytoplasmic transport GO:0016482 130 0.053
cell division GO:0051301 248 0.053
single organism behavior GO:0044708 391 0.053
imaginal disc derived appendage morphogenesis GO:0035114 395 0.053
nuclear transport GO:0051169 72 0.053
small gtpase mediated signal transduction GO:0007264 88 0.052
positive regulation of signaling GO:0023056 243 0.052
purine nucleotide metabolic process GO:0006163 146 0.051
death GO:0016265 284 0.050
regulation of localization GO:0032879 275 0.050
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.049
appendage morphogenesis GO:0035107 397 0.047
ion homeostasis GO:0050801 55 0.046
ribose phosphate metabolic process GO:0019693 145 0.046
imaginal disc derived appendage development GO:0048737 399 0.046
protein localization GO:0008104 284 0.045
cellular response to chemical stimulus GO:0070887 199 0.044
cellular macromolecule localization GO:0070727 220 0.044
nucleobase containing small molecule metabolic process GO:0055086 174 0.043
purine containing compound metabolic process GO:0072521 155 0.042
positive regulation of cell communication GO:0010647 250 0.041
body morphogenesis GO:0010171 2 0.041
regulation of organelle organization GO:0033043 196 0.041
ribonucleotide metabolic process GO:0009259 145 0.041
cellular protein modification process GO:0006464 438 0.041
camera type eye development GO:0043010 4 0.041
response to radiation GO:0009314 155 0.041
defense response to other organism GO:0098542 225 0.041
negative regulation of cell communication GO:0010648 223 0.040
response to organic substance GO:0010033 284 0.040
forebrain development GO:0030900 2 0.040
cell cycle checkpoint GO:0000075 95 0.040
cellular component assembly involved in morphogenesis GO:0010927 151 0.039
positive regulation of biosynthetic process GO:0009891 316 0.039
nucleoside phosphate metabolic process GO:0006753 162 0.039
negative regulation of cellular metabolic process GO:0031324 382 0.039
regulation of intracellular signal transduction GO:1902531 236 0.039
actin filament based process GO:0030029 220 0.039
protein transport GO:0015031 155 0.038
purine ribonucleotide metabolic process GO:0009150 145 0.038
small molecule metabolic process GO:0044281 305 0.038
negative regulation of biosynthetic process GO:0009890 277 0.037
organonitrogen compound metabolic process GO:1901564 318 0.037
negative regulation of cellular biosynthetic process GO:0031327 277 0.036
regulation of response to external stimulus GO:0032101 115 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.036
ras protein signal transduction GO:0007265 88 0.036
positive regulation of nucleic acid templated transcription GO:1903508 266 0.035
organelle fission GO:0048285 340 0.035
regulation of protein metabolic process GO:0051246 256 0.034
regulation of molecular function GO:0065009 217 0.034
positive regulation of molecular function GO:0044093 136 0.034
positive regulation of cellular biosynthetic process GO:0031328 316 0.034
negative regulation of signaling GO:0023057 219 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.033
regulation of catalytic activity GO:0050790 185 0.033
immune system process GO:0002376 347 0.033
positive regulation of signal transduction GO:0009967 223 0.033
cell migration GO:0016477 238 0.033
protein modification process GO:0036211 438 0.033
organic substance transport GO:0071702 257 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.032
regulation of phosphate metabolic process GO:0019220 210 0.032
chromosome organization GO:0051276 360 0.032
locomotory behavior GO:0007626 176 0.031
regulation of small gtpase mediated signal transduction GO:0051056 93 0.031
response to light stimulus GO:0009416 124 0.031
positive regulation of intracellular signal transduction GO:1902533 116 0.030
nucleotide metabolic process GO:0009117 161 0.030
regulation of cell differentiation GO:0045595 302 0.030
mesenchymal cell differentiation GO:0048762 1 0.030
regulation of synapse structure and activity GO:0050803 128 0.030
negative regulation of signal transduction GO:0009968 206 0.030
regulation of cellular protein metabolic process GO:0032268 243 0.030
protein localization to nucleus GO:0034504 55 0.030
single organism biosynthetic process GO:0044711 206 0.030
regulation of cellular localization GO:0060341 136 0.030
taxis GO:0042330 304 0.029
metal ion transport GO:0030001 74 0.029
positive regulation of catalytic activity GO:0043085 118 0.029
carbohydrate derivative biosynthetic process GO:1901137 85 0.029
negative regulation of transcription dna templated GO:0045892 237 0.029
positive regulation of cell migration GO:0030335 2 0.029
epithelial cell differentiation GO:0030855 322 0.029
intracellular protein transport GO:0006886 104 0.029
cell death GO:0008219 279 0.029
regulation of cell shape GO:0008360 113 0.028
enzyme linked receptor protein signaling pathway GO:0007167 179 0.028
positive regulation of phosphate metabolic process GO:0045937 139 0.028
posttranscriptional regulation of gene expression GO:0010608 145 0.028
protein complex biogenesis GO:0070271 201 0.028
regulation of protein localization GO:0032880 76 0.028
endocytosis GO:0006897 310 0.028
chromatin organization GO:0006325 207 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
regulation of lyase activity GO:0051339 14 0.027
regulation of multicellular organismal development GO:2000026 414 0.027
negative regulation of gene expression GO:0010629 387 0.026
negative regulation of rna metabolic process GO:0051253 251 0.026
homeostatic process GO:0042592 199 0.026
positive regulation of transport GO:0051050 92 0.026
positive regulation of apoptotic signaling pathway GO:2001235 4 0.026
developmental growth GO:0048589 280 0.026
sensory perception of chemical stimulus GO:0007606 116 0.026
imaginal disc derived leg morphogenesis GO:0007480 80 0.026
regulation of cell morphogenesis GO:0022604 163 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
limb development GO:0060173 1 0.025
leg disc development GO:0035218 92 0.025
wing disc morphogenesis GO:0007472 344 0.025
positive regulation of phosphorus metabolic process GO:0010562 139 0.025
defense response to bacterium GO:0042742 178 0.025
macromolecular complex assembly GO:0065003 256 0.025
regulation of gene expression epigenetic GO:0040029 128 0.025
embryonic morphogenesis GO:0048598 206 0.025
embryonic organ development GO:0048568 50 0.024
cell cycle phase transition GO:0044770 140 0.024
cellular protein localization GO:0034613 160 0.024
localization of cell GO:0051674 257 0.024
meiotic nuclear division GO:0007126 151 0.024
lateral inhibition GO:0046331 206 0.024
embryo development ending in birth or egg hatching GO:0009792 152 0.024
regulation of hydrolase activity GO:0051336 97 0.024
cellular protein complex assembly GO:0043623 71 0.024
striated muscle cell differentiation GO:0051146 90 0.024
defense response GO:0006952 300 0.024
endomembrane system organization GO:0010256 119 0.024
apoptotic process GO:0006915 159 0.023
central nervous system development GO:0007417 201 0.023
cell cell signaling involved in cell fate commitment GO:0045168 210 0.023
protein complex assembly GO:0006461 200 0.023
embryonic development via the syncytial blastoderm GO:0001700 148 0.023
synapse organization GO:0050808 196 0.023
organophosphate metabolic process GO:0019637 195 0.023
positive regulation of gene expression GO:0010628 290 0.022
regulation of nervous system development GO:0051960 248 0.022
phototransduction GO:0007602 52 0.022
covalent chromatin modification GO:0016569 106 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.022
regulation of establishment of protein localization GO:0070201 61 0.022
regulation of immune system process GO:0002682 176 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.021
mitotic cell cycle phase transition GO:0044772 138 0.021
protein phosphorylation GO:0006468 169 0.021
regulation of nucleocytoplasmic transport GO:0046822 35 0.021
vesicle mediated transport GO:0016192 381 0.021
negative regulation of multicellular organismal process GO:0051241 142 0.021
single organism cellular localization GO:1902580 180 0.021
cell motility GO:0048870 251 0.021
positive regulation of cellular component organization GO:0051130 156 0.021
regulation of programmed cell death GO:0043067 152 0.021
protein import into nucleus GO:0006606 51 0.021
regulation of transport GO:0051049 181 0.021
rna processing GO:0006396 147 0.020
regulation of cellular component biogenesis GO:0044087 201 0.020
organonitrogen compound biosynthetic process GO:1901566 117 0.020
connective tissue development GO:0061448 3 0.020
regulation of intracellular transport GO:0032386 64 0.020
regionalization GO:0003002 416 0.020
myofibril assembly GO:0030239 36 0.020
secretion GO:0046903 109 0.020
regulation of intracellular protein transport GO:0033157 46 0.020
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
axon development GO:0061564 297 0.020
regulation of neurogenesis GO:0050767 158 0.019
positive regulation of cyclase activity GO:0031281 9 0.019
ion transport GO:0006811 145 0.019
response to external biotic stimulus GO:0043207 293 0.019
leg disc morphogenesis GO:0007478 80 0.019
detection of abiotic stimulus GO:0009582 66 0.019
detection of external stimulus GO:0009581 66 0.019
eye morphogenesis GO:0048592 260 0.019
positive regulation of cell death GO:0010942 69 0.019
regulation of guanylate cyclase activity GO:0031282 1 0.019
regulation of purine nucleotide metabolic process GO:1900542 62 0.019
negative regulation of molecular function GO:0044092 51 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
negative regulation of mitotic cell cycle GO:0045930 109 0.019
chemotaxis GO:0006935 249 0.019
response to other organism GO:0051707 293 0.019
regulation of cell development GO:0060284 215 0.019
regulation of cell cycle process GO:0010564 181 0.019
phagocytosis GO:0006909 215 0.019
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.018
mesenchymal cell development GO:0014031 1 0.018
regulation of cytoplasmic transport GO:1903649 47 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
hindbrain development GO:0030902 2 0.018
positive regulation of programmed cell death GO:0043068 62 0.018
positive regulation of apoptotic process GO:0043065 47 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.018
stem cell differentiation GO:0048863 117 0.018
aromatic compound catabolic process GO:0019439 166 0.018
cellular catabolic process GO:0044248 372 0.018
nuclear division GO:0000280 332 0.017
ribose phosphate biosynthetic process GO:0046390 28 0.017
meiotic cell cycle GO:0051321 171 0.017
chromatin modification GO:0016568 147 0.017
neurotransmitter secretion GO:0007269 35 0.017
negative regulation of cell cycle GO:0045786 116 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
amine metabolic process GO:0009308 12 0.017
renal system development GO:0072001 72 0.017
detection of stimulus GO:0051606 156 0.017
nucleotide catabolic process GO:0009166 109 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
phosphorylation GO:0016310 294 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.016
rna localization GO:0006403 115 0.016
regulation of cell death GO:0010941 173 0.016
proteolysis GO:0006508 192 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
dna replication GO:0006260 48 0.016
organic substance catabolic process GO:1901575 308 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
dendrite development GO:0016358 204 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
ameboidal type cell migration GO:0001667 151 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
mrna processing GO:0006397 104 0.016
macromolecule catabolic process GO:0009057 161 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
heterocycle catabolic process GO:0046700 166 0.016
positive regulation of cell development GO:0010720 61 0.016
notch signaling pathway GO:0007219 120 0.015
dorsal closure GO:0007391 79 0.015
sensory organ morphogenesis GO:0090596 260 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
regulation of phosphorylation GO:0042325 147 0.015
response to oxygen containing compound GO:1901700 200 0.015
purine nucleoside metabolic process GO:0042278 127 0.015
heart development GO:0007507 82 0.015
positive regulation of behavior GO:0048520 19 0.015
negative regulation of developmental process GO:0051093 201 0.015
g protein coupled receptor signaling pathway GO:0007186 136 0.015
detection of light stimulus GO:0009583 58 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.015
nuclear export GO:0051168 24 0.015
asymmetric stem cell division GO:0098722 49 0.015
regulation of epithelial cell proliferation GO:0050678 4 0.015
chemical homeostasis GO:0048878 92 0.015
phagosome acidification GO:0090383 1 0.015
nucleoside catabolic process GO:0009164 112 0.015
regulation of catabolic process GO:0009894 170 0.015
secretion by cell GO:0032940 101 0.015
establishment of protein localization GO:0045184 163 0.015
brain development GO:0007420 120 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
positive regulation of phosphorylation GO:0042327 87 0.015
urogenital system development GO:0001655 72 0.015
negative regulation of protein metabolic process GO:0051248 85 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
regulation of protein import into nucleus GO:0042306 28 0.014
adult behavior GO:0030534 137 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
immune response GO:0006955 246 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.014
positive regulation of cell motility GO:2000147 3 0.014
actin filament organization GO:0007015 126 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
actomyosin structure organization GO:0031032 56 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
regulation of cell division GO:0051302 72 0.014
mitotic cell cycle checkpoint GO:0007093 88 0.014
regulation of nuclear division GO:0051783 58 0.014
cardiovascular system development GO:0072358 82 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
anterior posterior pattern specification GO:0009952 136 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
sensory perception of smell GO:0007608 80 0.014
embryonic pattern specification GO:0009880 174 0.014
dna metabolic process GO:0006259 227 0.014
protein targeting GO:0006605 64 0.013
cell proliferation GO:0008283 299 0.013
nitrogen compound transport GO:0071705 85 0.013
salt aversion GO:0035199 3 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
respiratory system development GO:0060541 213 0.013
protein localization to organelle GO:0033365 82 0.013
single organism catabolic process GO:0044712 228 0.013
extrinsic apoptotic signaling pathway GO:0097191 1 0.013
catabolic process GO:0009056 409 0.013
regulation of apoptotic process GO:0042981 130 0.013
mitotic nuclear division GO:0007067 213 0.013
axon guidance GO:0007411 233 0.013
positive regulation of developmental process GO:0051094 143 0.013
organ growth GO:0035265 56 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.013
cyclic purine nucleotide metabolic process GO:0052652 25 0.013
gland development GO:0048732 191 0.013
regulation of protein transport GO:0051223 57 0.013
response to biotic stimulus GO:0009607 294 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
negative regulation of cell cycle phase transition GO:1901988 103 0.013
translation GO:0006412 69 0.013
muscle organ development GO:0007517 127 0.013
cyclic nucleotide biosynthetic process GO:0009190 25 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
developmental maturation GO:0021700 172 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.013
nucleoside phosphate biosynthetic process GO:1901293 34 0.013
camera type eye morphogenesis GO:0048593 2 0.012
nucleotide biosynthetic process GO:0009165 34 0.012
nucleoside metabolic process GO:0009116 127 0.012
tube development GO:0035295 244 0.012
single organism nuclear import GO:1902593 51 0.012
regulation of growth GO:0040008 233 0.012
striated muscle myosin thick filament assembly GO:0071688 3 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
negative regulation of cell death GO:0060548 81 0.012
immune effector process GO:0002252 98 0.012
positive regulation of cyclic nucleotide metabolic process GO:0030801 9 0.012
positive regulation of response to external stimulus GO:0032103 44 0.012
rna splicing GO:0008380 83 0.012
ribonucleotide biosynthetic process GO:0009260 28 0.012
chromatin silencing GO:0006342 76 0.012
golgi organization GO:0007030 66 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
regulation of protein modification process GO:0031399 112 0.012
eye development GO:0001654 323 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
cell cycle arrest GO:0007050 4 0.012
regulation of protein stability GO:0031647 43 0.012
alternative mrna splicing via spliceosome GO:0000380 60 0.012
regulation of nucleotide metabolic process GO:0006140 62 0.012
purine nucleotide biosynthetic process GO:0006164 29 0.012
single organism membrane budding GO:1902591 2 0.012
protein targeting to nucleus GO:0044744 51 0.012
regulation of synaptic transmission GO:0050804 69 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
telencephalon development GO:0021537 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
regulation of meiosis GO:0040020 3 0.011
synaptic transmission GO:0007268 288 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
establishment of protein localization to organelle GO:0072594 62 0.011
striated muscle cell development GO:0055002 50 0.011
positive regulation of intracellular protein transport GO:0090316 30 0.011
intracellular ph reduction GO:0051452 7 0.011
cognition GO:0050890 141 0.011
nephron development GO:0072006 3 0.011
mrna splicing via spliceosome GO:0000398 73 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
sensory perception of mechanical stimulus GO:0050954 72 0.011
peptidyl threonine phosphorylation GO:0018107 2 0.011
regulation of synapse organization GO:0050807 110 0.011
regulation of response to stress GO:0080134 200 0.011
purine containing compound catabolic process GO:0072523 112 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
nephron epithelium development GO:0072009 3 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
spindle organization GO:0007051 253 0.011
gliogenesis GO:0042063 80 0.011
gtp metabolic process GO:0046039 72 0.011
asymmetric protein localization GO:0008105 33 0.011
regulation of autophagy GO:0010506 62 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
positive regulation of kinase activity GO:0033674 25 0.010
mrna metabolic process GO:0016071 124 0.010
regulation of dendrite development GO:0050773 37 0.010
rna splicing via transesterification reactions GO:0000375 73 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
regulation of proteolysis GO:0030162 87 0.010
tube morphogenesis GO:0035239 191 0.010
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
innate immune response GO:0045087 144 0.010
cation homeostasis GO:0055080 51 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
organic acid metabolic process GO:0006082 103 0.010
gtp catabolic process GO:0006184 72 0.010
axis specification GO:0009798 167 0.010
negative regulation of nervous system development GO:0051961 92 0.010
regulation of microtubule based process GO:0032886 49 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
neuropeptide signaling pathway GO:0007218 45 0.010
kidney epithelium development GO:0072073 3 0.010
peptidyl amino acid modification GO:0018193 105 0.010
divalent metal ion transport GO:0070838 26 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
retina development in camera type eye GO:0060041 4 0.010
epithelial cell development GO:0002064 274 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010

miple disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.013