Drosophila melanogaster

8 known processes

Hsp60D (Dmel_CG16954)

CG16954 gene product from transcript CG16954-RA

(Aliases: CG16954,Dmel\CG16954)

Hsp60D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 0.059
programmed cell death GO:0012501 257 0.051
compound eye development GO:0048749 307 0.049
vesicle mediated transport GO:0016192 381 0.047
regulation of multicellular organismal development GO:2000026 414 0.043
carboxylic acid metabolic process GO:0019752 92 0.043
small molecule metabolic process GO:0044281 305 0.042
cell death GO:0008219 279 0.039
lateral inhibition GO:0046331 206 0.036
organonitrogen compound metabolic process GO:1901564 318 0.036
death GO:0016265 284 0.035
cell cell signaling involved in cell fate commitment GO:0045168 210 0.034
cell proliferation GO:0008283 299 0.033
body morphogenesis GO:0010171 2 0.033
appendage development GO:0048736 401 0.032
regionalization GO:0003002 416 0.032
positive regulation of response to stimulus GO:0048584 323 0.032
protein modification process GO:0036211 438 0.030
single organism behavior GO:0044708 391 0.030
regulation of programmed cell death GO:0043067 152 0.029
cellular amino acid metabolic process GO:0006520 61 0.029
imaginal disc derived appendage morphogenesis GO:0035114 395 0.029
eye morphogenesis GO:0048592 260 0.028
photoreceptor cell differentiation GO:0046530 170 0.028
phagocytosis GO:0006909 215 0.028
apoptotic process GO:0006915 159 0.027
oxoacid metabolic process GO:0043436 103 0.027
positive regulation of cell communication GO:0010647 250 0.027
regulation of cellular ketone metabolic process GO:0010565 3 0.027
negative regulation of developmental process GO:0051093 201 0.026
regulation of intracellular signal transduction GO:1902531 236 0.026
imaginal disc derived appendage development GO:0048737 399 0.026
endocytosis GO:0006897 310 0.026
intracellular signal transduction GO:0035556 300 0.026
developmental maturation GO:0021700 172 0.025
organic acid metabolic process GO:0006082 103 0.025
locomotory behavior GO:0007626 176 0.025
compound eye morphogenesis GO:0001745 249 0.024
appendage morphogenesis GO:0035107 397 0.024
positive regulation of signaling GO:0023056 243 0.024
wing disc morphogenesis GO:0007472 344 0.023
cellular protein modification process GO:0006464 438 0.023
neurological system process GO:0050877 358 0.023
negative regulation of cell communication GO:0010648 223 0.023
organic substance transport GO:0071702 257 0.022
developmental growth GO:0048589 280 0.022
growth GO:0040007 359 0.021
regulation of apoptotic process GO:0042981 130 0.021
response to organic substance GO:0010033 284 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.021
phosphorylation GO:0016310 294 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
regulation of developmental growth GO:0048638 174 0.020
positive regulation of hydrolase activity GO:0051345 78 0.020
regulation of protein metabolic process GO:0051246 256 0.020
lipid metabolic process GO:0006629 121 0.020
regulation of cell death GO:0010941 173 0.020
positive regulation of signal transduction GO:0009967 223 0.020
nuclear division GO:0000280 332 0.020
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
camera type eye development GO:0043010 4 0.019
spindle organization GO:0007051 253 0.019
reproductive structure development GO:0048608 74 0.019
forebrain development GO:0030900 2 0.019
regulation of cell cycle process GO:0010564 181 0.019
eye photoreceptor cell differentiation GO:0001754 145 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
actin cytoskeleton organization GO:0030036 206 0.018
regulation of cell cycle GO:0051726 291 0.018
regulation of molecular function GO:0065009 217 0.018
regulation of cell differentiation GO:0045595 302 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
positive regulation of proteolysis GO:0045862 52 0.018
response to hexose GO:0009746 3 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
negative regulation of gene expression GO:0010629 387 0.017
regulation of cell development GO:0060284 215 0.017
memory GO:0007613 94 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
positive regulation of catabolic process GO:0009896 105 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.016
homeostatic process GO:0042592 199 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
sensory organ morphogenesis GO:0090596 260 0.016
response to other organism GO:0051707 293 0.016
organelle fission GO:0048285 340 0.016
imaginal disc pattern formation GO:0007447 91 0.016
response to abiotic stimulus GO:0009628 341 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
ras protein signal transduction GO:0007265 88 0.016
cell division GO:0051301 248 0.016
cell maturation GO:0048469 144 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
response to lipopolysaccharide GO:0032496 4 0.016
positive regulation of molecular function GO:0044093 136 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
retina development in camera type eye GO:0060041 4 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
amine metabolic process GO:0009308 12 0.016
stem cell differentiation GO:0048863 117 0.016
regulation of transport GO:0051049 181 0.016
learning or memory GO:0007611 141 0.016
meiotic cell cycle process GO:1903046 132 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
regulation of nervous system development GO:0051960 248 0.016
cellular ketone metabolic process GO:0042180 24 0.015
male gamete generation GO:0048232 201 0.015
Fly
response to extracellular stimulus GO:0009991 116 0.015
synaptic transmission GO:0007268 288 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
negative regulation of signaling GO:0023057 219 0.015
regulation of localization GO:0032879 275 0.015
nucleotide metabolic process GO:0009117 161 0.015
meiotic cell cycle GO:0051321 171 0.015
response to temperature stimulus GO:0009266 106 0.015
molting cycle chitin based cuticle GO:0007591 56 0.015
small gtpase mediated signal transduction GO:0007264 88 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
zymogen activation GO:0031638 20 0.014
protein modification by small protein conjugation GO:0032446 79 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.014
telencephalon development GO:0021537 2 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
epithelial cell differentiation GO:0030855 322 0.014
Fly
establishment or maintenance of cell polarity GO:0007163 167 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
organophosphate metabolic process GO:0019637 195 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
tripartite regional subdivision GO:0007351 103 0.014
macromolecular complex assembly GO:0065003 256 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
wnt signaling pathway GO:0016055 98 0.014
regulation of cellular catabolic process GO:0031329 157 0.013
blastoderm segmentation GO:0007350 159 0.013
regulation of proteolysis GO:0030162 87 0.013
regulation of hydrolase activity GO:0051336 97 0.013
cellular macromolecule localization GO:0070727 220 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
segmentation GO:0035282 207 0.013
response to oxygen containing compound GO:1901700 200 0.013
nicotinamide nucleotide metabolic process GO:0046496 2 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
response to monosaccharide GO:0034284 4 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
cytoskeleton dependent cytokinesis GO:0061640 81 0.013
regulation of multi organism process GO:0043900 131 0.013
somatic muscle development GO:0007525 66 0.013
regulation of catalytic activity GO:0050790 185 0.013
actin filament based process GO:0030029 220 0.013
ion transport GO:0006811 145 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
defense response to other organism GO:0098542 225 0.013
protein processing GO:0016485 68 0.013
kidney development GO:0001822 3 0.013
negative regulation of signal transduction GO:0009968 206 0.013
response to nutrient levels GO:0031667 114 0.013
regulation of immune system process GO:0002682 176 0.013
cytokinesis GO:0000910 90 0.013
axis specification GO:0009798 167 0.013
cellular homeostasis GO:0019725 80 0.012
positive regulation of endopeptidase activity GO:0010950 26 0.012
protein heterooligomerization GO:0051291 4 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
catabolic process GO:0009056 409 0.012
dna metabolic process GO:0006259 227 0.012
locomotor rhythm GO:0045475 56 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.012
regulation of wnt signaling pathway GO:0030111 68 0.012
protein localization GO:0008104 284 0.012
cellular response to organic substance GO:0071310 132 0.012
establishment of protein localization GO:0045184 163 0.012
camera type eye morphogenesis GO:0048593 2 0.012
central nervous system development GO:0007417 201 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
defense response GO:0006952 300 0.012
organic substance catabolic process GO:1901575 308 0.012
eye photoreceptor cell development GO:0042462 81 0.012
detection of chemical stimulus GO:0009593 93 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
single organism intracellular transport GO:1902582 207 0.012
single organism membrane organization GO:0044802 93 0.012
establishment of localization in cell GO:0051649 402 0.012
response to radiation GO:0009314 155 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
cognition GO:0050890 141 0.012
cellularization GO:0007349 90 0.012
tissue morphogenesis GO:0048729 297 0.012
smoothened signaling pathway GO:0007224 49 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
regulation of cellular localization GO:0060341 136 0.012
regulation of response to external stimulus GO:0032101 115 0.011
single organism catabolic process GO:0044712 228 0.011
stem cell development GO:0048864 79 0.011
cellular amine metabolic process GO:0044106 12 0.011
taxis GO:0042330 304 0.011
organelle localization GO:0051640 148 0.011
wing disc pattern formation GO:0035222 66 0.011
single organism biosynthetic process GO:0044711 206 0.011
spermatogenesis GO:0007283 200 0.011
Fly
positive regulation of apoptotic signaling pathway GO:2001235 4 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
protein ubiquitination GO:0016567 70 0.011
oocyte construction GO:0007308 112 0.011
photoreceptor cell development GO:0042461 96 0.011
negative regulation of cell death GO:0060548 81 0.011
pyridine containing compound metabolic process GO:0072524 3 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
epithelial cell development GO:0002064 274 0.011
Fly
axonogenesis GO:0007409 290 0.011
digestive system development GO:0055123 149 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
embryonic pattern specification GO:0009880 174 0.011
oxidoreduction coenzyme metabolic process GO:0006733 2 0.011
heterocycle catabolic process GO:0046700 166 0.011
endomembrane system organization GO:0010256 119 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
wound healing GO:0042060 75 0.011
muscle organ development GO:0007517 127 0.011
developmental pigmentation GO:0048066 68 0.011
protein complex assembly GO:0006461 200 0.011
compound eye photoreceptor development GO:0042051 78 0.010
muscle structure development GO:0061061 224 0.010
developmental programmed cell death GO:0010623 138 0.010
negative regulation of nucleic acid templated transcription GO:1903507 240 0.010
positive regulation of protein metabolic process GO:0051247 128 0.010
germ line stem cell maintenance GO:0030718 50 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
positive regulation of cell death GO:0010942 69 0.010
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.010
carbohydrate transport GO:0008643 4 0.010
cellular catabolic process GO:0044248 372 0.010
response to wounding GO:0009611 94 0.010
membrane organization GO:0061024 112 0.010
response to organic cyclic compound GO:0014070 89 0.010
embryonic axis specification GO:0000578 107 0.010
rhythmic behavior GO:0007622 76 0.010
oocyte anterior posterior axis specification GO:0007314 72 0.010
gland development GO:0048732 191 0.010
defense response to bacterium GO:0042742 178 0.010
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.010
skeletal muscle fiber development GO:0048741 3 0.010
oocyte development GO:0048599 124 0.010
chromatin organization GO:0006325 207 0.010
regulation of catabolic process GO:0009894 170 0.010
protein phosphorylation GO:0006468 169 0.010
phosphate ion transport GO:0006817 4 0.010

Hsp60D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.015
nervous system disease DOID:863 0 0.013
musculoskeletal system disease DOID:17 0 0.011
inherited metabolic disorder DOID:655 0 0.011
cardiovascular system disease DOID:1287 0 0.010