Drosophila melanogaster

34 known processes

Est-6 (Dmel_CG6917)

Esterase 6

(Aliases: est6,Est,Est-D,Est-5,Est-5B,Est6,Dmel\CG6917,EST6,CG6917,EST-6,EST-5,est-6,Est 6)

Est-6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multi organism behavior GO:0051705 175 0.509
cell cell signaling involved in cell fate commitment GO:0045168 210 0.312
mating GO:0007618 120 0.303
mating behavior GO:0007617 106 0.227
ethanolamine containing compound metabolic process GO:0042439 4 0.216
neurotransmitter metabolic process GO:0042133 2 0.212
lateral inhibition GO:0046331 206 0.201
cell adhesion involved in heart morphogenesis GO:0061343 12 0.190
male mating behavior GO:0060179 70 0.178
Fly
multi multicellular organism process GO:0044706 123 0.163
Fly
multicellular organismal reproductive behavior GO:0033057 110 0.135
Fly
axon guidance GO:0007411 233 0.130
hormone catabolic process GO:0042447 3 0.126
Fly
reproductive behavior GO:0019098 122 0.124
choline metabolic process GO:0019695 1 0.122
multi organism reproductive behavior GO:0044705 121 0.114
imaginal disc derived wing hair organization GO:0035317 45 0.112
wing disc morphogenesis GO:0007472 344 0.111
courtship behavior GO:0007619 68 0.111
female meiotic division GO:0007143 70 0.110
single organism behavior GO:0044708 391 0.109
Fly
synaptic target recognition GO:0008039 45 0.103
acetate ester metabolic process GO:1900619 2 0.096
acetylcholine metabolic process GO:0008291 2 0.093
steroid catabolic process GO:0006706 1 0.093
axon development GO:0061564 297 0.093
imaginal disc derived appendage development GO:0048737 399 0.093
lipid metabolic process GO:0006629 121 0.092
Fly
regulation of tube architecture open tracheal system GO:0035152 68 0.091
oxoacid metabolic process GO:0043436 103 0.089
chemotaxis GO:0006935 249 0.087
amine catabolic process GO:0009310 1 0.087
acetylcholine catabolic process GO:0006581 1 0.084
meiotic chromosome segregation GO:0045132 59 0.082
response to abiotic stimulus GO:0009628 341 0.082
organic substance transport GO:0071702 257 0.081
organonitrogen compound metabolic process GO:1901564 318 0.078
cellular amine metabolic process GO:0044106 12 0.078
peripheral nervous system development GO:0007422 52 0.077
septate junction assembly GO:0019991 26 0.077
sensory perception of chemical stimulus GO:0007606 116 0.075
response to other organism GO:0051707 293 0.073
adult behavior GO:0030534 137 0.073
Fly
defense response GO:0006952 300 0.073
non sensory hair organization GO:0035316 47 0.072
synaptic transmission GO:0007268 288 0.071
regionalization GO:0003002 416 0.069
neurological system process GO:0050877 358 0.065
sensory perception GO:0007600 196 0.065
heart development GO:0007507 82 0.064
cell cell junction assembly GO:0007043 38 0.064
post embryonic appendage morphogenesis GO:0035120 385 0.061
amine metabolic process GO:0009308 12 0.060
small molecule metabolic process GO:0044281 305 0.060
biological adhesion GO:0022610 138 0.059
response to external biotic stimulus GO:0043207 293 0.059
neurotransmitter catabolic process GO:0042135 1 0.059
cellular catabolic process GO:0044248 372 0.058
Fly
organic acid metabolic process GO:0006082 103 0.058
carboxylic acid metabolic process GO:0019752 92 0.057
regulation of tube size GO:0035150 46 0.057
male gamete generation GO:0048232 201 0.057
motor neuron axon guidance GO:0008045 58 0.056
cellular amino acid metabolic process GO:0006520 61 0.056
localization of cell GO:0051674 257 0.054
choline catabolic process GO:0042426 1 0.054
organic substance catabolic process GO:1901575 308 0.052
Fly
response to biotic stimulus GO:0009607 294 0.052
circulatory system development GO:0072359 82 0.051
organelle fission GO:0048285 340 0.051
appendage morphogenesis GO:0035107 397 0.051
sterol homeostasis GO:0055092 4 0.050
circadian rhythm GO:0007623 105 0.049
appendage development GO:0048736 401 0.048
homeostatic process GO:0042592 199 0.047
respiratory system development GO:0060541 213 0.046
immune system process GO:0002376 347 0.046
epithelial cell differentiation GO:0030855 322 0.045
cellular ketone metabolic process GO:0042180 24 0.045
columnar cuboidal epithelial cell development GO:0002066 249 0.045
spermatogenesis GO:0007283 200 0.044
regulation of tube size open tracheal system GO:0035151 43 0.044
cellular biogenic amine catabolic process GO:0042402 1 0.044
response to light stimulus GO:0009416 124 0.044
vesicle mediated transport GO:0016192 381 0.042
chromosome segregation GO:0007059 157 0.042
glycerolipid catabolic process GO:0046503 3 0.040
ovarian follicle cell development GO:0030707 248 0.040
nuclear division GO:0000280 332 0.039
imaginal disc derived appendage morphogenesis GO:0035114 395 0.039
imaginal disc derived wing morphogenesis GO:0007476 337 0.039
wound healing GO:0042060 75 0.039
regulation of hormone levels GO:0010817 40 0.039
female meiosis chromosome segregation GO:0016321 33 0.038
meiotic cell cycle process GO:1903046 132 0.036
organic hydroxy compound metabolic process GO:1901615 83 0.036
maintenance of location GO:0051235 73 0.035
immune response GO:0006955 246 0.035
spermatid differentiation GO:0048515 114 0.034
rhythmic process GO:0048511 106 0.034
innate immune response GO:0045087 144 0.034
catabolic process GO:0009056 409 0.033
Fly
heart morphogenesis GO:0003007 32 0.033
hair cell differentiation GO:0035315 47 0.032
phagocytosis GO:0006909 215 0.032
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.031
lipid localization GO:0010876 54 0.031
open tracheal system development GO:0007424 204 0.031
single organism biosynthetic process GO:0044711 206 0.031
cellular response to endogenous stimulus GO:0071495 80 0.030
response to organic substance GO:0010033 284 0.029
Fly
apical junction assembly GO:0043297 32 0.029
epithelial cell development GO:0002064 274 0.029
response to organophosphorus GO:0046683 2 0.029
regulation of cell cycle GO:0051726 291 0.028
ovarian follicle cell migration GO:0007297 121 0.027
cellular protein modification process GO:0006464 438 0.027
enzyme linked receptor protein signaling pathway GO:0007167 179 0.027
neutral lipid biosynthetic process GO:0046460 2 0.026
response to oxygen containing compound GO:1901700 200 0.026
Fly
epidermal cell differentiation GO:0009913 51 0.026
defense response to other organism GO:0098542 225 0.025
pigment metabolic process GO:0042440 84 0.025
protein transmembrane transport GO:0071806 4 0.025
cellular response to chemical stimulus GO:0070887 199 0.024
kidney development GO:0001822 3 0.024
melanotic encapsulation of foreign target GO:0035011 30 0.024
lipid catabolic process GO:0016042 21 0.024
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
regulation of transport GO:0051049 181 0.023
anion homeostasis GO:0055081 3 0.023
cell adhesion GO:0007155 136 0.023
establishment of blood nerve barrier GO:0008065 2 0.023
cellular hormone metabolic process GO:0034754 23 0.023
Fly
single organism catabolic process GO:0044712 228 0.023
Fly
positive regulation of transport GO:0051050 92 0.022
energy taxis GO:0009453 21 0.022
response to starvation GO:0042594 97 0.022
response to ethanol GO:0045471 59 0.022
Fly
death GO:0016265 284 0.022
protein modification process GO:0036211 438 0.021
cell cell junction organization GO:0045216 55 0.021
cellular response to dna damage stimulus GO:0006974 223 0.021
response to radiation GO:0009314 155 0.021
regulation of localization GO:0032879 275 0.021
response to wounding GO:0009611 94 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
epidermis development GO:0008544 65 0.020
phototaxis GO:0042331 21 0.020
skin development GO:0043588 65 0.019
lipid storage GO:0019915 38 0.019
feeding behavior GO:0007631 50 0.019
aging GO:0007568 143 0.019
growth GO:0040007 359 0.019
response to fungus GO:0009620 50 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
maintenance of imaginal disc derived wing hair orientation GO:0035321 3 0.019
cell motility GO:0048870 251 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
cellular lipid metabolic process GO:0044255 83 0.018
Fly
lipid homeostasis GO:0055088 33 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
response to copper ion GO:0046688 4 0.018
protein complex assembly GO:0006461 200 0.018
insecticide metabolic process GO:0017143 2 0.018
chaeta development GO:0022416 97 0.018
sleep GO:0030431 49 0.018
camera type eye development GO:0043010 4 0.017
behavioral response to ethanol GO:0048149 49 0.017
Fly
medium chain fatty acid metabolic process GO:0051791 1 0.017
meiotic cell cycle GO:0051321 171 0.017
triglyceride biosynthetic process GO:0019432 2 0.017
g protein coupled receptor signaling pathway GO:0007186 136 0.017
gland development GO:0048732 191 0.017
regulation of behavior GO:0050795 75 0.017
phosphatidylethanolamine metabolic process GO:0046337 1 0.016
response to decreased oxygen levels GO:0036293 58 0.016
pheromone biosynthetic process GO:0042811 3 0.016
sensory perception of smell GO:0007608 80 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
cellular homeostasis GO:0019725 80 0.016
mesoderm development GO:0007498 78 0.016
actin filament based process GO:0030029 220 0.016
macromolecular complex assembly GO:0065003 256 0.016
organic hydroxy compound catabolic process GO:1901616 4 0.016
tissue migration GO:0090130 155 0.016
positive regulation of response to stimulus GO:0048584 323 0.015
epithelium migration GO:0090132 148 0.015
neutral lipid catabolic process GO:0046461 3 0.015
alditol phosphate metabolic process GO:0052646 2 0.015
developmental growth GO:0048589 280 0.015
cellular response to organic substance GO:0071310 132 0.015
ion homeostasis GO:0050801 55 0.015
organophosphate metabolic process GO:0019637 195 0.015
body morphogenesis GO:0010171 2 0.015
cholesterol homeostasis GO:0042632 3 0.015
humoral immune response GO:0006959 117 0.015
male courtship behavior GO:0008049 63 0.014
monocarboxylic acid transport GO:0015718 3 0.014
positive regulation of lipid storage GO:0010884 4 0.014
regulation of catalytic activity GO:0050790 185 0.014
ameboidal type cell migration GO:0001667 151 0.014
nitrogen compound transport GO:0071705 85 0.014
response to endogenous stimulus GO:0009719 119 0.014
forebrain development GO:0030900 2 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of lipid transport GO:0032368 3 0.014
multicellular organismal aging GO:0010259 140 0.014
regulation of anatomical structure size GO:0090066 163 0.014
alcohol metabolic process GO:0006066 25 0.014
cellular biogenic amine metabolic process GO:0006576 9 0.014
triglyceride catabolic process GO:0019433 3 0.013
epithelial cell migration GO:0010631 148 0.013
regulation of response to stress GO:0080134 200 0.013
neuron projection guidance GO:0097485 241 0.013
phospholipid homeostasis GO:0055091 1 0.013
aromatic compound catabolic process GO:0019439 166 0.013
juvenile hormone metabolic process GO:0006716 3 0.013
Fly
hormone metabolic process GO:0042445 33 0.013
positive regulation of molecular function GO:0044093 136 0.013
regulation of developmental growth GO:0048638 174 0.013
regulation of cholesterol transport GO:0032374 1 0.013
positive regulation of gene expression GO:0010628 290 0.013
nucleus organization GO:0006997 45 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
response to temperature stimulus GO:0009266 106 0.012
endocytosis GO:0006897 310 0.012
cognition GO:0050890 141 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
negative regulation of developmental process GO:0051093 201 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
negative regulation of cell cycle GO:0045786 116 0.012
cell migration GO:0016477 238 0.012
heterocycle catabolic process GO:0046700 166 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
positive regulation of cell communication GO:0010647 250 0.012
response to cold GO:0009409 13 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
anatomical structure homeostasis GO:0060249 97 0.012
positive regulation of signaling GO:0023056 243 0.012
regulation of protein metabolic process GO:0051246 256 0.012
cellularization GO:0007349 90 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
l amino acid import GO:0043092 2 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
organophosphate catabolic process GO:0046434 112 0.011
response to alcohol GO:0097305 95 0.011
Fly
hemolymph coagulation GO:0042381 10 0.011
sperm storage GO:0046693 10 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
sensory organ morphogenesis GO:0090596 260 0.011
intracellular protein transmembrane import GO:0044743 4 0.011
acylglycerol biosynthetic process GO:0046463 2 0.011
glycoprotein metabolic process GO:0009100 41 0.011
nad metabolic process GO:0019674 1 0.011
defense response to bacterium GO:0042742 178 0.011
acylglycerol catabolic process GO:0046464 3 0.011
positive regulation of sequestering of triglyceride GO:0010890 1 0.011
proteolysis GO:0006508 192 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
regulation of hydrolase activity GO:0051336 97 0.011
cell recognition GO:0008037 102 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
rhythmic behavior GO:0007622 76 0.011
regulation of system process GO:0044057 36 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
cell proliferation GO:0008283 299 0.011
cellular modified amino acid metabolic process GO:0006575 45 0.011
proximal distal pattern formation GO:0009954 15 0.011
larval development GO:0002164 104 0.010
negative regulation of biosynthetic process GO:0009890 277 0.010
regulation of neurotransmitter levels GO:0001505 38 0.010
establishment of localization in cell GO:0051649 402 0.010
response to nitrogen compound GO:1901698 90 0.010
cellular response to nitrogen compound GO:1901699 51 0.010
developmental programmed cell death GO:0010623 138 0.010
chemical homeostasis GO:0048878 92 0.010
positive regulation of cell migration GO:0030335 2 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
neuromuscular junction development GO:0007528 149 0.010
regulation of cellular response to stress GO:0080135 89 0.010
carbohydrate metabolic process GO:0005975 82 0.010
regulation of molecular function GO:0065009 217 0.010

Est-6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.184
familial hyperlipidemia DOID:1168 0 0.184
lipid metabolism disorder DOID:3146 0 0.184
familial combined hyperlipidemia DOID:13809 0 0.184
inherited metabolic disorder DOID:655 0 0.184
carbohydrate metabolism disease DOID:0050013 0 0.088
glucose metabolism disease DOID:4194 0 0.088
acquired metabolic disease DOID:0060158 0 0.088
disease of anatomical entity DOID:7 0 0.076
diabetes mellitus DOID:9351 0 0.044
type 2 diabetes mellitus DOID:9352 0 0.019
cardiovascular system disease DOID:1287 0 0.018
nervous system disease DOID:863 0 0.018
familial lipoprotein lipase deficiency DOID:14118 0 0.017
central nervous system disease DOID:331 0 0.010
neurodegenerative disease DOID:1289 0 0.010