Drosophila melanogaster

113 known processes

CDC45L (Dmel_CG3658)

CG3658 gene product from transcript CG3658-RA

(Aliases: anon-1Ec,Cdc45,dCDC45,D,CG3658,EG:BACR7A4.11,CDC45,DmCdc45,Dmel\CG3658)

CDC45L biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 227 0.992
dna replication GO:0006260 48 0.968
cell cycle dna replication GO:0044786 23 0.955
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.944
dna conformation change GO:0071103 105 0.858
dna damage checkpoint GO:0000077 78 0.837
g2 dna damage checkpoint GO:0031572 69 0.831
mitotic dna damage checkpoint GO:0044773 74 0.804
nuclear dna replication GO:0033260 1 0.798
Yeast
positive regulation of macromolecule metabolic process GO:0010604 405 0.752
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.726
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.710
mitotic g2 m transition checkpoint GO:0044818 70 0.702
meiotic cell cycle process GO:1903046 132 0.701
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.687
protein dna complex subunit organization GO:0071824 86 0.675
Yeast
chromosome organization GO:0051276 360 0.643
nuclear division GO:0000280 332 0.569
dna dependent dna replication GO:0006261 17 0.568
Yeast
meiotic chromosome segregation GO:0045132 59 0.550
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.539
Yeast
recombinational repair GO:0000725 13 0.517
Yeast
protein dna complex assembly GO:0065004 63 0.516
Yeast
double strand break repair via homologous recombination GO:0000724 13 0.474
Yeast
positive regulation of rna metabolic process GO:0051254 271 0.452
organelle fission GO:0048285 340 0.427
negative regulation of cell cycle phase transition GO:1901988 103 0.398
double strand break repair GO:0006302 26 0.392
Yeast
regulation of mitotic cell cycle phase transition GO:1901990 130 0.372
dna recombination GO:0006310 32 0.369
Yeast
dna integrity checkpoint GO:0031570 81 0.369
cell cycle checkpoint GO:0000075 95 0.359
death GO:0016265 284 0.357
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.353
Yeast
dna biosynthetic process GO:0071897 24 0.349
single organism biosynthetic process GO:0044711 206 0.337
Yeast
dna duplex unwinding GO:0032508 16 0.315
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.301
Yeast
regulation of cell cycle GO:0051726 291 0.295
negative regulation of transcription dna templated GO:0045892 237 0.294
Yeast
gliogenesis GO:0042063 80 0.292
mitotic cell cycle checkpoint GO:0007093 88 0.274
mitotic g2 dna damage checkpoint GO:0007095 69 0.268
reciprocal meiotic recombination GO:0007131 19 0.266
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.263
Yeast
dna geometric change GO:0032392 16 0.256
dna repair GO:0006281 54 0.250
Yeast
dna endoreduplication GO:0042023 22 0.249
chromatin organization GO:0006325 207 0.245
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.231
cell division GO:0051301 248 0.226
regulation of mitotic cell cycle GO:0007346 190 0.217
regulation of cell cycle process GO:0010564 181 0.215
positive regulation of rna biosynthetic process GO:1902680 266 0.208
positive regulation of biosynthetic process GO:0009891 316 0.202
negative regulation of gene expression epigenetic GO:0045814 77 0.196
Yeast
negative regulation of cell cycle process GO:0010948 109 0.194
cell death GO:0008219 279 0.194
regulation of apoptotic process GO:0042981 130 0.194
eye development GO:0001654 323 0.190
regulation of programmed cell death GO:0043067 152 0.189
dna packaging GO:0006323 91 0.189
programmed cell death GO:0012501 257 0.184
regulation of cell cycle phase transition GO:1901987 130 0.181
negative regulation of cellular metabolic process GO:0031324 382 0.181
Yeast
spermatogenesis GO:0007283 200 0.177
regulation of localization GO:0032879 275 0.173
macromolecular complex assembly GO:0065003 256 0.170
Yeast
small molecule metabolic process GO:0044281 305 0.165
eye morphogenesis GO:0048592 260 0.158
purine ribonucleoside metabolic process GO:0046128 127 0.157
male gamete generation GO:0048232 201 0.149
organic substance transport GO:0071702 257 0.147
aromatic compound catabolic process GO:0019439 166 0.143
mitotic dna integrity checkpoint GO:0044774 75 0.143
regulation of dna metabolic process GO:0051052 34 0.138
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.137
regulation of hydrolase activity GO:0051336 97 0.137
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.124
regulation of neurogenesis GO:0050767 158 0.123
negative regulation of mitotic cell cycle GO:0045930 109 0.122
positive regulation of cellular biosynthetic process GO:0031328 316 0.121
apoptotic process GO:0006915 159 0.118
vesicle mediated transport GO:0016192 381 0.117
chromatin remodeling GO:0006338 72 0.115
cell proliferation GO:0008283 299 0.115
ribonucleoside metabolic process GO:0009119 127 0.114
purine nucleoside triphosphate metabolic process GO:0009144 119 0.113
single organism intracellular transport GO:1902582 207 0.110
purine nucleoside metabolic process GO:0042278 127 0.105
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.104
establishment of localization in cell GO:0051649 402 0.101
negative regulation of cellular biosynthetic process GO:0031327 277 0.100
Yeast
positive regulation of gene expression GO:0010628 290 0.098
double strand break repair via nonhomologous end joining GO:0006303 5 0.098
regulation of nervous system development GO:0051960 248 0.092
sensory organ morphogenesis GO:0090596 260 0.089
regulation of cell death GO:0010941 173 0.088
chromatin modification GO:0016568 147 0.087
cellular protein modification process GO:0006464 438 0.084
cellular catabolic process GO:0044248 372 0.083
regulation of mitosis GO:0007088 56 0.083
cytoplasmic transport GO:0016482 130 0.081
positive regulation of nucleic acid templated transcription GO:1903508 266 0.079
negative regulation of rna biosynthetic process GO:1902679 240 0.078
Yeast
embryo development ending in birth or egg hatching GO:0009792 152 0.075
Worm
positive regulation of multicellular organismal process GO:0051240 143 0.074
response to abiotic stimulus GO:0009628 341 0.072
dna replication initiation GO:0006270 6 0.072
Yeast
negative regulation of cell cycle GO:0045786 116 0.072
negative regulation of biosynthetic process GO:0009890 277 0.071
Yeast
mitotic cell cycle phase transition GO:0044772 138 0.071
meiosis i GO:0007127 59 0.070
mitotic nuclear division GO:0007067 213 0.069
heterocycle catabolic process GO:0046700 166 0.068
cellular macromolecule localization GO:0070727 220 0.068
gonad development GO:0008406 50 0.067
body morphogenesis GO:0010171 2 0.067
histone modification GO:0016570 106 0.066
organic substance catabolic process GO:1901575 308 0.066
positive regulation of transcription dna templated GO:0045893 266 0.064
protein transport GO:0015031 155 0.064
organelle assembly GO:0070925 198 0.063
positive regulation of developmental process GO:0051094 143 0.063
regulation of gene expression epigenetic GO:0040029 128 0.062
Yeast
nucleotide metabolic process GO:0009117 161 0.061
meiotic nuclear division GO:0007126 151 0.058
response to biotic stimulus GO:0009607 294 0.056
response to external biotic stimulus GO:0043207 293 0.056
protein modification process GO:0036211 438 0.055
negative regulation of apoptotic process GO:0043066 63 0.053
regulation of cell division GO:0051302 72 0.053
cellular macromolecular complex assembly GO:0034622 153 0.052
Yeast
negative regulation of rna metabolic process GO:0051253 251 0.050
Yeast
regulation of multicellular organismal development GO:2000026 414 0.050
compound eye morphogenesis GO:0001745 249 0.049
purine containing compound metabolic process GO:0072521 155 0.049
catabolic process GO:0009056 409 0.048
endocytosis GO:0006897 310 0.048
regulation of cellular localization GO:0060341 136 0.048
regulation of cytoplasmic transport GO:1903649 47 0.047
compound eye development GO:0048749 307 0.047
chromosome segregation GO:0007059 157 0.046
chromosome separation GO:0051304 42 0.046
negative regulation of gene expression GO:0010629 387 0.045
Yeast
regulation of mitotic sister chromatid segregation GO:0033047 28 0.044
regulation of protein metabolic process GO:0051246 256 0.044
nucleobase containing compound catabolic process GO:0034655 165 0.042
dna amplification GO:0006277 11 0.041
regulation of transport GO:0051049 181 0.041
regulation of developmental growth GO:0048638 174 0.040
covalent chromatin modification GO:0016569 106 0.039
ribose phosphate metabolic process GO:0019693 145 0.039
glycosyl compound metabolic process GO:1901657 127 0.039
purine nucleotide metabolic process GO:0006163 146 0.038
ribonucleotide metabolic process GO:0009259 145 0.038
imaginal disc derived appendage morphogenesis GO:0035114 395 0.037
eggshell chorion gene amplification GO:0007307 9 0.037
organonitrogen compound metabolic process GO:1901564 318 0.037
nucleoside phosphate metabolic process GO:0006753 162 0.037
aging GO:0007568 143 0.037
response to light stimulus GO:0009416 124 0.036
female meiosis chromosome segregation GO:0016321 33 0.036
reproductive structure development GO:0048608 74 0.036
protein complex assembly GO:0006461 200 0.035
regulation of catalytic activity GO:0050790 185 0.035
purine nucleoside catabolic process GO:0006152 112 0.034
negative regulation of programmed cell death GO:0043069 72 0.034
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.032
regulation of molecular function GO:0065009 217 0.032
larval development GO:0002164 104 0.032
cell cycle phase transition GO:0044770 140 0.032
cell fate determination GO:0001709 91 0.031
glycosyl compound catabolic process GO:1901658 112 0.031
purine nucleotide catabolic process GO:0006195 109 0.030
nucleoside triphosphate metabolic process GO:0009141 120 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.029
positive regulation of programmed cell death GO:0043068 62 0.029
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.028
camera type eye morphogenesis GO:0048593 2 0.028
carbohydrate derivative catabolic process GO:1901136 118 0.028
purine nucleoside triphosphate catabolic process GO:0009146 108 0.027
negative regulation of nucleic acid templated transcription GO:1903507 240 0.027
Yeast
cell motility GO:0048870 251 0.027
regulation of growth GO:0040008 233 0.027
atp dependent chromatin remodeling GO:0043044 22 0.027
multicellular organism growth GO:0035264 46 0.026
nucleoside catabolic process GO:0009164 112 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.026
positive regulation of gliogenesis GO:0014015 5 0.026
regulation of nucleotide catabolic process GO:0030811 48 0.026
translesion synthesis GO:0019985 2 0.026
organophosphate metabolic process GO:0019637 195 0.026
purine ribonucleoside catabolic process GO:0046130 112 0.025
protein localization GO:0008104 284 0.025
actin filament based process GO:0030029 220 0.025
regulation of phosphate metabolic process GO:0019220 210 0.024
positive regulation of nucleoside metabolic process GO:0045979 47 0.024
establishment of protein localization GO:0045184 163 0.024
camera type eye development GO:0043010 4 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.022
small gtpase mediated signal transduction GO:0007264 88 0.022
neuroblast proliferation GO:0007405 74 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
response to other organism GO:0051707 293 0.022
nuclear transport GO:0051169 72 0.021
postreplication repair GO:0006301 2 0.021
homeostatic process GO:0042592 199 0.020
nucleotide catabolic process GO:0009166 109 0.020
regulation of cellular catabolic process GO:0031329 157 0.020
negative regulation of cell death GO:0060548 81 0.020
amine metabolic process GO:0009308 12 0.019
nucleotide excision repair GO:0006289 8 0.019
regulation of response to stress GO:0080134 200 0.019
central nervous system development GO:0007417 201 0.019
regulation of chromatin silencing GO:0031935 36 0.019
Yeast
ribonucleotide catabolic process GO:0009261 109 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
imaginal disc derived wing morphogenesis GO:0007476 337 0.019
response to radiation GO:0009314 155 0.018
tube morphogenesis GO:0035239 191 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
sex differentiation GO:0007548 81 0.018
rna localization GO:0006403 115 0.018
dendrite development GO:0016358 204 0.018
cellular protein complex assembly GO:0043623 71 0.018
nitrogen compound transport GO:0071705 85 0.018
neuron recognition GO:0008038 101 0.018
nls bearing protein import into nucleus GO:0006607 5 0.017
axon development GO:0061564 297 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
guanosine containing compound metabolic process GO:1901068 74 0.017
anatomical structure homeostasis GO:0060249 97 0.017
regulation of dna repair GO:0006282 5 0.017
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.017
nucleosome mobilization GO:0042766 9 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
meiotic cell cycle GO:0051321 171 0.017
establishment of rna localization GO:0051236 47 0.016
appendage development GO:0048736 401 0.016
protein localization to nucleus GO:0034504 55 0.016
positive regulation of neurogenesis GO:0050769 41 0.016
organophosphate catabolic process GO:0046434 112 0.016
gtp metabolic process GO:0046039 72 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
sterol biosynthetic process GO:0016126 9 0.016
telomere organization GO:0032200 21 0.016
single organism nuclear import GO:1902593 51 0.016
guanosine containing compound catabolic process GO:1901069 74 0.016
gtp catabolic process GO:0006184 72 0.015
mitotic sister chromatid segregation GO:0000070 87 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
nucleoside metabolic process GO:0009116 127 0.015
protein localization to organelle GO:0033365 82 0.015
endomembrane system organization GO:0010256 119 0.015
imaginal disc derived appendage development GO:0048737 399 0.015
reproductive system development GO:0061458 74 0.015
intracellular transport GO:0046907 228 0.015
locomotory behavior GO:0007626 176 0.015
regulation of cell differentiation GO:0045595 302 0.015
wing disc morphogenesis GO:0007472 344 0.015
regulation of nucleoside metabolic process GO:0009118 50 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.014
regulation of catabolic process GO:0009894 170 0.014
regulation of purine nucleotide metabolic process GO:1900542 62 0.014
protein ubiquitination GO:0016567 70 0.014
regulation of organelle organization GO:0033043 196 0.014
regulation of nucleocytoplasmic transport GO:0046822 35 0.014
regulation of protein deacetylation GO:0090311 2 0.014
positive regulation of endopeptidase activity GO:0010950 26 0.014
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.014
epithelial cell differentiation GO:0030855 322 0.014
lipid metabolic process GO:0006629 121 0.014
zymogen activation GO:0031638 20 0.014
nuclear pore organization GO:0006999 1 0.014
regulation of dna replication GO:0006275 13 0.014
development of primary sexual characteristics GO:0045137 50 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
meiotic chromosome separation GO:0051307 8 0.014
positive regulation of cell cycle GO:0045787 43 0.013
protein import GO:0017038 55 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
single organism cellular localization GO:1902580 180 0.013
nucleobase containing compound transport GO:0015931 56 0.013
regulation of nuclear division GO:0051783 58 0.013
regulation of purine nucleotide catabolic process GO:0033121 48 0.013
cellular protein localization GO:0034613 160 0.013
regulation of endopeptidase activity GO:0052548 36 0.013
positive regulation of cell proliferation GO:0008284 47 0.012
regulation of cellular response to stress GO:0080135 89 0.012
dendrite morphogenesis GO:0048813 199 0.012
regulation of dna dependent dna replication GO:0090329 6 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
post embryonic appendage morphogenesis GO:0035120 385 0.012
negative regulation of dna metabolic process GO:0051053 12 0.012
response to uv GO:0009411 24 0.012
response to bacterium GO:0009617 198 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
positive regulation of cell development GO:0010720 61 0.012
single organism catabolic process GO:0044712 228 0.012
protein targeting GO:0006605 64 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
phosphorylation GO:0016310 294 0.012
ovarian follicle cell development GO:0030707 248 0.012
intercellular bridge organization GO:0043063 14 0.012
mitotic sister chromatid separation GO:0051306 30 0.012
chromatin silencing GO:0006342 76 0.012
Yeast
regulation of protein localization GO:0032880 76 0.012
phagocytosis GO:0006909 215 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
axonogenesis GO:0007409 290 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
response to lipopolysaccharide GO:0032496 4 0.012
regulation of nucleotide metabolic process GO:0006140 62 0.011
nuclear import GO:0051170 51 0.011
secretion by cell GO:0032940 101 0.011
secretion GO:0046903 109 0.011
regulation of cysteine type endopeptidase activity GO:2000116 27 0.011
response to organic substance GO:0010033 284 0.011
single organism behavior GO:0044708 391 0.011
positive regulation of transport GO:0051050 92 0.011
ribonucleoside monophosphate metabolic process GO:0009161 51 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.010
rna transport GO:0050658 46 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
regulation of cell proliferation GO:0042127 163 0.010
multicellular organismal aging GO:0010259 140 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
nucleosome organization GO:0034728 59 0.010

CDC45L disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
organ system cancer DOID:0050686 0 0.034
disease of anatomical entity DOID:7 0 0.031