Drosophila melanogaster

0 known processes

Her (Dmel_CG5927)

HES-related

(Aliases: Dmel\CG5927,bHLHc21,CG5927)

Her biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic morphogenesis GO:0048598 206 0.220
response to abiotic stimulus GO:0009628 341 0.121
Fly
protein complex biogenesis GO:0070271 201 0.074
imaginal disc derived wing morphogenesis GO:0007476 337 0.074
regulation of gene expression epigenetic GO:0040029 128 0.071
tissue morphogenesis GO:0048729 297 0.070
epithelial cell differentiation GO:0030855 322 0.065
macromolecular complex assembly GO:0065003 256 0.063
negative regulation of nucleic acid templated transcription GO:1903507 240 0.059
Rat Fly
tube development GO:0035295 244 0.058
Fly
morphogenesis of an epithelium GO:0002009 276 0.057
photoreceptor cell differentiation GO:0046530 170 0.054
programmed cell death GO:0012501 257 0.054
sensory organ morphogenesis GO:0090596 260 0.054
lateral inhibition GO:0046331 206 0.053
compound eye development GO:0048749 307 0.053
negative regulation of biosynthetic process GO:0009890 277 0.053
Rat Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.052
negative regulation of cellular metabolic process GO:0031324 382 0.052
Rat Fly
anterior posterior axis specification GO:0009948 109 0.051
eye photoreceptor cell differentiation GO:0001754 145 0.050
segmentation GO:0035282 207 0.050
cell cell signaling involved in cell fate commitment GO:0045168 210 0.049
dendrite morphogenesis GO:0048813 199 0.048
kidney development GO:0001822 3 0.047
negative regulation of rna metabolic process GO:0051253 251 0.047
Rat Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.045
Rat Fly
single organism behavior GO:0044708 391 0.044
axonogenesis GO:0007409 290 0.042
Zebrafish
establishment or maintenance of cell polarity GO:0007163 167 0.041
regulation of multicellular organismal development GO:2000026 414 0.040
developmental programmed cell death GO:0010623 138 0.040
compound eye morphogenesis GO:0001745 249 0.040
imaginal disc derived appendage development GO:0048737 399 0.040
protein complex assembly GO:0006461 200 0.039
dendrite development GO:0016358 204 0.039
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.039
Rat Fly
cell death GO:0008219 279 0.039
regulation of anatomical structure morphogenesis GO:0022603 242 0.039
regulation of cell differentiation GO:0045595 302 0.038
Human
forebrain development GO:0030900 2 0.038
digestive system development GO:0055123 149 0.037
anterior posterior pattern specification GO:0009952 136 0.037
negative regulation of gene expression GO:0010629 387 0.037
Rat Fly
compound eye photoreceptor cell differentiation GO:0001751 140 0.037
larval behavior GO:0030537 42 0.036
cellular response to dna damage stimulus GO:0006974 223 0.036
respiratory system development GO:0060541 213 0.036
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.036
Mouse Fly
regionalization GO:0003002 416 0.035
organelle fission GO:0048285 340 0.035
developmental maturation GO:0021700 172 0.035
appendage development GO:0048736 401 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.034
Rat Fly
regulation of intracellular signal transduction GO:1902531 236 0.034
salivary gland development GO:0007431 162 0.034
Fly
nuclear division GO:0000280 332 0.033
establishment of localization in cell GO:0051649 402 0.033
digestive tract development GO:0048565 149 0.033
central nervous system development GO:0007417 201 0.033
negative regulation of transcription dna templated GO:0045892 237 0.032
Rat Fly
adult behavior GO:0030534 137 0.032
wing disc morphogenesis GO:0007472 344 0.031
positive regulation of signaling GO:0023056 243 0.031
nephron morphogenesis GO:0072028 3 0.031
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.031
small molecule metabolic process GO:0044281 305 0.031
locomotory behavior GO:0007626 176 0.030
immune system process GO:0002376 347 0.029
salivary gland morphogenesis GO:0007435 145 0.029
Fly
tube morphogenesis GO:0035239 191 0.029
Fly
gland development GO:0048732 191 0.029
Fly
exocrine system development GO:0035272 162 0.029
Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.029
Rat Fly
embryonic pattern specification GO:0009880 174 0.029
nephron development GO:0072006 3 0.029
cellular component assembly involved in morphogenesis GO:0010927 151 0.029
dorsal ventral pattern formation GO:0009953 133 0.028
cellular macromolecular complex assembly GO:0034622 153 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.028
telencephalon development GO:0021537 2 0.028
response to radiation GO:0009314 155 0.028
eye development GO:0001654 323 0.027
epithelial cell development GO:0002064 274 0.027
positive regulation of macromolecule metabolic process GO:0010604 405 0.027
digestive tract morphogenesis GO:0048546 127 0.027
single organism cellular localization GO:1902580 180 0.026
positive regulation of cell communication GO:0010647 250 0.026
death GO:0016265 284 0.026
positive regulation of molecular function GO:0044093 136 0.026
columnar cuboidal epithelial cell development GO:0002066 249 0.026
positive regulation of rna biosynthetic process GO:1902680 266 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
spermatogenesis GO:0007283 200 0.025
negative regulation of cellular biosynthetic process GO:0031327 277 0.025
Rat Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.025
Mouse Fly
regulation of nervous system development GO:0051960 248 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.025
olfactory behavior GO:0042048 97 0.025
post embryonic appendage morphogenesis GO:0035120 385 0.025
appendage morphogenesis GO:0035107 397 0.024
regulation of molecular function GO:0065009 217 0.024
regulation of cell development GO:0060284 215 0.024
positive regulation of gene expression GO:0010628 290 0.024
brain development GO:0007420 120 0.024
mesoderm development GO:0007498 78 0.023
intracellular signal transduction GO:0035556 300 0.023
establishment of protein localization GO:0045184 163 0.023
adult locomotory behavior GO:0008344 76 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
embryonic development via the syncytial blastoderm GO:0001700 148 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
nephron epithelium development GO:0072009 3 0.023
organic substance catabolic process GO:1901575 308 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
ras protein signal transduction GO:0007265 88 0.023
regulation of cellular protein metabolic process GO:0032268 243 0.023
muscle structure development GO:0061061 224 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
positive regulation of rna metabolic process GO:0051254 271 0.022
regulation of mitotic cell cycle GO:0007346 190 0.022
growth GO:0040007 359 0.022
morphogenesis of embryonic epithelium GO:0016331 94 0.022
cell division GO:0051301 248 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.022
Rat Fly
cell maturation GO:0048469 144 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.022
Fly
protein modification process GO:0036211 438 0.021
kidney epithelium development GO:0072073 3 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
cell adhesion GO:0007155 136 0.021
epithelial tube morphogenesis GO:0060562 88 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
positive regulation of cellular biosynthetic process GO:0031328 316 0.021
phosphorylation GO:0016310 294 0.021
positive regulation of biosynthetic process GO:0009891 316 0.021
r7 cell differentiation GO:0045466 43 0.021
positive regulation of signal transduction GO:0009967 223 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
negative regulation of signaling GO:0023057 219 0.021
hindbrain development GO:0030902 2 0.021
open tracheal system development GO:0007424 204 0.020
Fly
chorion containing eggshell formation GO:0007304 105 0.020
eye morphogenesis GO:0048592 260 0.020
axon development GO:0061564 297 0.020
Zebrafish
neurological system process GO:0050877 358 0.020
positive regulation of multicellular organismal process GO:0051240 143 0.020
gene silencing GO:0016458 138 0.020
male gamete generation GO:0048232 201 0.020
cell fate determination GO:0001709 91 0.020
blastoderm segmentation GO:0007350 159 0.020
formation of organ boundary GO:0010160 30 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
catabolic process GO:0009056 409 0.019
formation of anatomical boundary GO:0048859 37 0.019
positive regulation of intracellular signal transduction GO:1902533 116 0.019
negative regulation of signal transduction GO:0009968 206 0.019
posttranscriptional regulation of gene expression GO:0010608 145 0.019
body morphogenesis GO:0010171 2 0.019
nephron tubule development GO:0072080 3 0.019
cell proliferation GO:0008283 299 0.019
Human
apoptotic process GO:0006915 159 0.018
notch signaling pathway GO:0007219 120 0.018
Human
regulation of cellular ketone metabolic process GO:0010565 3 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
chromosome organization GO:0051276 360 0.018
eggshell formation GO:0030703 105 0.018
rna processing GO:0006396 147 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
negative regulation of immune system process GO:0002683 50 0.018
nephron tubule morphogenesis GO:0072078 3 0.018
organonitrogen compound metabolic process GO:1901564 318 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.018
small gtpase mediated signal transduction GO:0007264 88 0.017
response to organic substance GO:0010033 284 0.017
histolysis GO:0007559 102 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
protein localization GO:0008104 284 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.017
negative regulation of developmental process GO:0051093 201 0.017
Human
organic acid metabolic process GO:0006082 103 0.017
tripartite regional subdivision GO:0007351 103 0.017
dosage compensation GO:0007549 16 0.017
positive regulation of developmental process GO:0051094 143 0.017
organic substance transport GO:0071702 257 0.017
gland morphogenesis GO:0022612 145 0.017
Fly
mitotic nuclear division GO:0007067 213 0.017
actin cytoskeleton organization GO:0030036 206 0.017
photoreceptor cell development GO:0042461 96 0.017
hematopoietic progenitor cell differentiation GO:0002244 1 0.017
regulation of phosphorylation GO:0042325 147 0.017
developmental growth GO:0048589 280 0.017
regulation of protein metabolic process GO:0051246 256 0.016
single organism biosynthetic process GO:0044711 206 0.016
ovarian follicle cell development GO:0030707 248 0.016
embryonic axis specification GO:0000578 107 0.016
regulation of cell proliferation GO:0042127 163 0.016
Human
head development GO:0060322 135 0.016
protein phosphorylation GO:0006468 169 0.016
regulation of multi organism process GO:0043900 131 0.016
negative regulation of cell communication GO:0010648 223 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.016
endocytosis GO:0006897 310 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
regulation of catalytic activity GO:0050790 185 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
localization of cell GO:0051674 257 0.016
regulation of cell cycle GO:0051726 291 0.016
regulation of response to stress GO:0080134 200 0.015
regulation of cell death GO:0010941 173 0.015
vesicle mediated transport GO:0016192 381 0.015
spindle organization GO:0007051 253 0.015
cellular response to radiation GO:0071478 52 0.015
startle response GO:0001964 16 0.015
response to heat GO:0009408 63 0.015
cellular macromolecule localization GO:0070727 220 0.015
cell migration GO:0016477 238 0.015
mrna metabolic process GO:0016071 124 0.015
cellular catabolic process GO:0044248 372 0.015
mesenchymal cell differentiation GO:0048762 1 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
tissue death GO:0016271 102 0.015
connective tissue development GO:0061448 3 0.014
Human
positive regulation of catalytic activity GO:0043085 118 0.014
cellular protein localization GO:0034613 160 0.014
axis specification GO:0009798 167 0.014
organelle assembly GO:0070925 198 0.014
regulation of cell cycle process GO:0010564 181 0.014
regulation of neuron differentiation GO:0045664 103 0.014
single organism catabolic process GO:0044712 228 0.014
eggshell chorion assembly GO:0007306 66 0.014
camera type eye development GO:0043010 4 0.014
cellular protein modification process GO:0006464 438 0.014
establishment of planar polarity GO:0001736 87 0.014
gene silencing by rna GO:0031047 57 0.014
cell projection assembly GO:0030031 94 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
regulation of programmed cell death GO:0043067 152 0.014
smoothened signaling pathway GO:0007224 49 0.014
regulation of neurogenesis GO:0050767 158 0.014
response to lipopolysaccharide GO:0032496 4 0.013
regulation of embryonic development GO:0045995 68 0.013
chromatin organization GO:0006325 207 0.013
innate immune response GO:0045087 144 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
mitotic cell cycle embryonic GO:0045448 38 0.013
regulation of anatomical structure size GO:0090066 163 0.013
dna metabolic process GO:0006259 227 0.013
alternative mrna splicing via spliceosome GO:0000380 60 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
axon guidance GO:0007411 233 0.013
posttranscriptional gene silencing GO:0016441 46 0.013
biological adhesion GO:0022610 138 0.013
regulation of immune system process GO:0002682 176 0.013
regulation of gene silencing GO:0060968 63 0.013
amine metabolic process GO:0009308 12 0.013
wing disc pattern formation GO:0035222 66 0.013
chemosensory behavior GO:0007635 106 0.013
rhythmic process GO:0048511 106 0.013
immune response GO:0006955 246 0.013
neuron fate commitment GO:0048663 50 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
protein dna complex subunit organization GO:0071824 86 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
phagocytosis GO:0006909 215 0.012
oocyte axis specification GO:0007309 108 0.012
posttranscriptional gene silencing by rna GO:0035194 45 0.012
mesenchymal cell development GO:0014031 1 0.012
rna splicing via transesterification reactions GO:0000375 73 0.012
mrna processing GO:0006397 104 0.012
memory GO:0007613 94 0.012
urogenital system development GO:0001655 72 0.012
taxis GO:0042330 304 0.012
response to glucose GO:0009749 2 0.012
mapk cascade GO:0000165 107 0.012
regulation of catabolic process GO:0009894 170 0.012
cellular response to abiotic stimulus GO:0071214 58 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
actin filament organization GO:0007015 126 0.012
response to oxygen containing compound GO:1901700 200 0.012
compound eye photoreceptor development GO:0042051 78 0.012
chromatin assembly or disassembly GO:0006333 52 0.012
oxoacid metabolic process GO:0043436 103 0.012
autophagy GO:0006914 108 0.012
chromatin silencing GO:0006342 76 0.012
positive regulation of cell migration GO:0030335 2 0.012
cell fate specification GO:0001708 71 0.012
stem cell proliferation GO:0072089 88 0.011
salivary gland histolysis GO:0035070 88 0.011
regulation of mrna processing GO:0050684 71 0.011
regulation of cell division GO:0051302 72 0.011
neuron projection guidance GO:0097485 241 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
actin filament based process GO:0030029 220 0.011
cellular amine metabolic process GO:0044106 12 0.011
synapse organization GO:0050808 196 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
tissue migration GO:0090130 155 0.011
proteolysis GO:0006508 192 0.011
synaptic transmission GO:0007268 288 0.011
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.011
cell growth GO:0016049 108 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.011
regulation of localization GO:0032879 275 0.011
nephron epithelium morphogenesis GO:0072088 3 0.011
regulation of transport GO:0051049 181 0.011
rna splicing GO:0008380 83 0.011
microtubule organizing center organization GO:0031023 168 0.011
oocyte construction GO:0007308 112 0.011
oocyte differentiation GO:0009994 145 0.011
cranial nerve development GO:0021545 1 0.011
cellular ketone metabolic process GO:0042180 24 0.011
response to temperature stimulus GO:0009266 106 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
ameboidal type cell migration GO:0001667 151 0.011
response to hexose GO:0009746 3 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.011
regulation of cell shape GO:0008360 113 0.011
cognition GO:0050890 141 0.010
renal system development GO:0072001 72 0.010
regulation of developmental growth GO:0048638 174 0.010
regulation of mrna splicing via spliceosome GO:0048024 64 0.010
humoral immune response GO:0006959 117 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
regulation of mrna metabolic process GO:1903311 72 0.010
rna localization GO:0006403 115 0.010
regulation of organelle organization GO:0033043 196 0.010
establishment of tissue polarity GO:0007164 87 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
intracellular transport GO:0046907 228 0.010
stem cell differentiation GO:0048863 117 0.010
Human
response to biotic stimulus GO:0009607 294 0.010
mitotic dna integrity checkpoint GO:0044774 75 0.010
dna packaging GO:0006323 91 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.010
defense response GO:0006952 300 0.010
peripheral nervous system development GO:0007422 52 0.010
Zebrafish
oocyte development GO:0048599 124 0.010
meiotic nuclear division GO:0007126 151 0.010
secondary metabolic process GO:0019748 75 0.010

Her disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
Human
musculoskeletal system disease DOID:17 0 0.020
Human
bone disease DOID:0080001 0 0.015
Human
connective tissue disease DOID:65 0 0.015
Human
nervous system disease DOID:863 0 0.010