Drosophila melanogaster

54 known processes

Crc (Dmel_CG9429)

Calreticulin

(Aliases: CG9429,anon-EST:Liang-2.17,clone 2.17,anon-EST:fe3D7,potp,anon-EST:Liang-2.11,eth,Dmel\CG9429,clone 2.11,Clr)

Crc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
centrosome cycle GO:0007098 137 0.631
centrosome organization GO:0051297 163 0.520
cellular catabolic process GO:0044248 372 0.346
microtubule organizing center organization GO:0031023 168 0.329
negative regulation of gene expression GO:0010629 387 0.318
Human Rat
aging GO:0007568 143 0.305
Human
regulation of cell proliferation GO:0042127 163 0.290
Human
spermatogenesis GO:0007283 200 0.268
Rat
centrosome duplication GO:0051298 121 0.264
catabolic process GO:0009056 409 0.210
multicellular organismal aging GO:0010259 140 0.197
cell death GO:0008219 279 0.190
cell proliferation GO:0008283 299 0.175
Human
regulation of intracellular signal transduction GO:1902531 236 0.172
regulation of cellular response to stress GO:0080135 89 0.167
negative regulation of rna metabolic process GO:0051253 251 0.153
Human
death GO:0016265 284 0.151
positive regulation of cellular biosynthetic process GO:0031328 316 0.149
Human
determination of adult lifespan GO:0008340 137 0.145
cellular protein modification process GO:0006464 438 0.140
regulation of anatomical structure size GO:0090066 163 0.127
regulation of response to stress GO:0080134 200 0.122
protein complex assembly GO:0006461 200 0.119
protein modification process GO:0036211 438 0.112
intracellular signal transduction GO:0035556 300 0.109
regulation of programmed cell death GO:0043067 152 0.108
positive regulation of cell communication GO:0010647 250 0.108
apoptotic process GO:0006915 159 0.108
programmed cell death GO:0012501 257 0.106
cellular protein localization GO:0034613 160 0.104
Human
eye development GO:0001654 323 0.093
response to organic substance GO:0010033 284 0.088
Rat
positive regulation of biosynthetic process GO:0009891 316 0.086
Human
sesquiterpenoid metabolic process GO:0006714 3 0.079
protein complex biogenesis GO:0070271 201 0.079
meiotic nuclear division GO:0007126 151 0.076
positive regulation of response to stimulus GO:0048584 323 0.075
Human
meiotic cell cycle GO:0051321 171 0.070
male gamete generation GO:0048232 201 0.067
Rat
proteolysis GO:0006508 192 0.065
nucleosome assembly GO:0006334 35 0.064
intracellular transport GO:0046907 228 0.061
Human
inter male aggressive behavior GO:0002121 60 0.061
notch signaling pathway GO:0007219 120 0.059
cellular macromolecule localization GO:0070727 220 0.058
Human
regulation of cell death GO:0010941 173 0.057
organic substance catabolic process GO:1901575 308 0.056
organonitrogen compound metabolic process GO:1901564 318 0.056
appendage development GO:0048736 401 0.054
regulation of anatomical structure morphogenesis GO:0022603 242 0.052
Human
endocytosis GO:0006897 310 0.052
response to biotic stimulus GO:0009607 294 0.049
regulation of protein metabolic process GO:0051246 256 0.048
Rat
phosphorylation GO:0016310 294 0.048
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.046
Human
imaginal disc derived appendage morphogenesis GO:0035114 395 0.046
regulation of multicellular organismal development GO:2000026 414 0.044
Human
appendage morphogenesis GO:0035107 397 0.043
organic substance transport GO:0071702 257 0.043
Human
regulation of cell morphogenesis GO:0022604 163 0.042
Human
developmental pigmentation GO:0048066 68 0.041
regulation of catalytic activity GO:0050790 185 0.041
single organism biosynthetic process GO:0044711 206 0.040
biological adhesion GO:0022610 138 0.040
Human
single organism carbohydrate metabolic process GO:0044723 72 0.039
growth GO:0040007 359 0.038
carbohydrate derivative metabolic process GO:1901135 217 0.038
posttranscriptional regulation of gene expression GO:0010608 145 0.038
Rat
pigmentation GO:0043473 75 0.038
small molecule metabolic process GO:0044281 305 0.037
post embryonic appendage morphogenesis GO:0035120 385 0.036
anatomical structure homeostasis GO:0060249 97 0.034
wing disc morphogenesis GO:0007472 344 0.034
positive regulation of intracellular signal transduction GO:1902533 116 0.034
cellular response to nutrient levels GO:0031669 62 0.034
single organism intracellular transport GO:1902582 207 0.033
Human
positive regulation of signal transduction GO:0009967 223 0.033
cytoplasmic transport GO:0016482 130 0.033
Human
regulation of rna splicing GO:0043484 69 0.031
carbohydrate derivative catabolic process GO:1901136 118 0.030
macromolecular complex assembly GO:0065003 256 0.030
cellular response to starvation GO:0009267 61 0.030
positive regulation of signaling GO:0023056 243 0.030
organelle fission GO:0048285 340 0.029
cell aging GO:0007569 2 0.029
Human
chaeta development GO:0022416 97 0.029
regulation of organelle organization GO:0033043 196 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.028
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.027
Human
nuclear division GO:0000280 332 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
Rat
aggressive behavior GO:0002118 63 0.027
regulation of transport GO:0051049 181 0.027
regulation of molecular function GO:0065009 217 0.026
salivary gland morphogenesis GO:0007435 145 0.026
response to other organism GO:0051707 293 0.026
dna metabolic process GO:0006259 227 0.026
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
Human Rat
negative regulation of cellular metabolic process GO:0031324 382 0.025
Human Rat
cell adhesion GO:0007155 136 0.024
Human
monocarboxylic acid metabolic process GO:0032787 29 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
primary alcohol metabolic process GO:0034308 2 0.024
response to metal ion GO:0010038 23 0.023
Rat
macromolecule catabolic process GO:0009057 161 0.023
regulation of growth GO:0040008 233 0.023
lipid localization GO:0010876 54 0.023
hydrogen peroxide metabolic process GO:0042743 6 0.022
meiotic cell cycle process GO:1903046 132 0.022
regionalization GO:0003002 416 0.022
single organism cellular localization GO:1902580 180 0.022
protein localization GO:0008104 284 0.022
Human
response to oxidative stress GO:0006979 86 0.021
regulation of catabolic process GO:0009894 170 0.021
central nervous system development GO:0007417 201 0.021
androgen metabolic process GO:0008209 1 0.021
response to abiotic stimulus GO:0009628 341 0.021
vesicle mediated transport GO:0016192 381 0.021
heart development GO:0007507 82 0.020
Rat
dendrite development GO:0016358 204 0.020
spermatid differentiation GO:0048515 114 0.020
regulation of apoptotic process GO:0042981 130 0.019
morphogenesis of an epithelium GO:0002009 276 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
maintenance of location GO:0051235 73 0.017
establishment of protein localization to organelle GO:0072594 62 0.017
endomembrane system organization GO:0010256 119 0.017
intrinsic apoptotic signaling pathway GO:0097193 16 0.017
regulation of immune system process GO:0002682 176 0.017
Human
developmental programmed cell death GO:0010623 138 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.017
phagocytosis GO:0006909 215 0.017
dna conformation change GO:0071103 105 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
nucleotide metabolic process GO:0009117 161 0.017
regulation of cell shape GO:0008360 113 0.017
positive regulation of gene expression GO:0010628 290 0.016
mitotic spindle elongation GO:0000022 81 0.015
reactive oxygen species metabolic process GO:0072593 22 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
positive regulation of cell differentiation GO:0045597 64 0.015
Human
peptidyl amino acid modification GO:0018193 105 0.015
negative regulation of transcription dna templated GO:0045892 237 0.014
Human
epithelial cell differentiation GO:0030855 322 0.014
spermatid development GO:0007286 98 0.014
single organism catabolic process GO:0044712 228 0.014
regulation of protein modification process GO:0031399 112 0.014
cellular ketone metabolic process GO:0042180 24 0.014
gtp catabolic process GO:0006184 72 0.014
regulation of neurogenesis GO:0050767 158 0.013
Human
cellular response to oxidative stress GO:0034599 28 0.013
respiratory system development GO:0060541 213 0.013
positive regulation of molecular function GO:0044093 136 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
reproductive system development GO:0061458 74 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
forebrain development GO:0030900 2 0.013
regulation of viral genome replication GO:0045069 4 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
Human
response to radiation GO:0009314 155 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
regulation of localization GO:0032879 275 0.012
Human
cellular protein catabolic process GO:0044257 83 0.012
regulation of cell differentiation GO:0045595 302 0.012
Human
dendrite morphogenesis GO:0048813 199 0.012
membrane organization GO:0061024 112 0.012
regulation of hormone levels GO:0010817 40 0.012
establishment of protein localization GO:0045184 163 0.012
Human
regulation of phosphorylation GO:0042325 147 0.012
intracellular protein transport GO:0006886 104 0.012
Human
positive regulation of cell proliferation GO:0008284 47 0.012
Human
regulation of phosphate metabolic process GO:0019220 210 0.012
brain development GO:0007420 120 0.012
gland morphogenesis GO:0022612 145 0.012
protein localization to organelle GO:0033365 82 0.012
Human
actin cytoskeleton organization GO:0030036 206 0.012
maintenance of cell polarity GO:0030011 18 0.012
protein phosphorylation GO:0006468 169 0.011
rna splicing GO:0008380 83 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
golgi organization GO:0007030 66 0.011
organic hydroxy compound catabolic process GO:1901616 4 0.011
stem cell differentiation GO:0048863 117 0.011
exocrine system development GO:0035272 162 0.011
protein targeting GO:0006605 64 0.011
cellular response to reactive oxygen species GO:0034614 14 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
salivary gland development GO:0007431 162 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.010
Human
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
larval development GO:0002164 104 0.010
inorganic cation transmembrane transport GO:0098662 61 0.010
response to endoplasmic reticulum stress GO:0034976 28 0.010
regulation of nervous system development GO:0051960 248 0.010
Human

Crc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
immune system cancer DOID:0060083 0 0.012
Human
hematologic cancer DOID:2531 0 0.012
Human
cancer DOID:162 0 0.012
Human
disease of cellular proliferation DOID:14566 0 0.012
Human
organ system cancer DOID:0050686 0 0.012
Human
bone marrow cancer DOID:4960 0 0.012
Human