Drosophila melanogaster

57 known processes

Ndc80 (Dmel_CG9938)

CG9938 gene product from transcript CG9938-RA

(Aliases: Dmel\CG9938,Hec1,dmNdc80,hec1,CG9938)

Ndc80 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear division GO:0000280 332 0.994
metaphase plate congression GO:0051310 19 0.962
sister chromatid segregation GO:0000819 92 0.957
chromosome organization GO:0051276 360 0.945
meiotic chromosome segregation GO:0045132 59 0.891
chromosome segregation GO:0007059 157 0.880
establishment of chromosome localization GO:0051303 20 0.858
mitotic spindle organization GO:0007052 220 0.842
chromosome localization GO:0050000 20 0.840
mitotic nuclear division GO:0007067 213 0.816
mitotic metaphase plate congression GO:0007080 13 0.809
spindle organization GO:0007051 253 0.796
establishment of organelle localization GO:0051656 122 0.795
organelle fission GO:0048285 340 0.775
female meiotic division GO:0007143 70 0.763
spindle assembly involved in mitosis GO:0090307 50 0.728
mitotic sister chromatid segregation GO:0000070 87 0.656
protein dna complex assembly GO:0065004 63 0.552
mitotic spindle elongation GO:0000022 81 0.534
dna conformation change GO:0071103 105 0.467
protein dna complex subunit organization GO:0071824 86 0.429
dna metabolic process GO:0006259 227 0.327
centromere complex assembly GO:0034508 7 0.324
organelle localization GO:0051640 148 0.320
mitotic spindle midzone assembly GO:0051256 1 0.310
kinetochore organization GO:0051383 9 0.307
spindle midzone assembly GO:0051255 4 0.292
dna packaging GO:0006323 91 0.247
protein localization to organelle GO:0033365 82 0.242
cell cycle dna replication GO:0044786 23 0.214
mitotic chromosome condensation GO:0007076 22 0.207
mitotic sister chromatid separation GO:0051306 30 0.204
telomere organization GO:0032200 21 0.189
protein complex biogenesis GO:0070271 201 0.188
nuclear dna replication GO:0033260 1 0.181
dna dependent dna replication GO:0006261 17 0.177
chromosome movement towards spindle pole GO:0051305 4 0.165
establishment of localization in cell GO:0051649 402 0.161
centrosome cycle GO:0007098 137 0.161
protein complex assembly GO:0006461 200 0.156
dna endoreduplication GO:0042023 22 0.156
meiotic nuclear division GO:0007126 151 0.142
regulation of mitotic cell cycle GO:0007346 190 0.134
regulation of mitosis GO:0007088 56 0.122
cellular protein complex assembly GO:0043623 71 0.120
centrosome duplication GO:0051298 121 0.110
dna replication initiation GO:0006270 6 0.100
spindle elongation GO:0051231 83 0.096
cell cycle phase transition GO:0044770 140 0.092
negative regulation of gene expression epigenetic GO:0045814 77 0.091
macromolecular complex assembly GO:0065003 256 0.089
cell division GO:0051301 248 0.085
mitotic spindle stabilization GO:0043148 6 0.085
microtubule organizing center organization GO:0031023 168 0.085
dna replication GO:0006260 48 0.081
single organism biosynthetic process GO:0044711 206 0.081
cellular macromolecule localization GO:0070727 220 0.080
cell cell signaling involved in cell fate commitment GO:0045168 210 0.079
dna geometric change GO:0032392 16 0.079
meiotic cell cycle process GO:1903046 132 0.078
meiotic cell cycle GO:0051321 171 0.077
regulation of neurogenesis GO:0050767 158 0.077
neuroblast proliferation GO:0007405 74 0.076
centrosome organization GO:0051297 163 0.076
organelle assembly GO:0070925 198 0.075
chromosome condensation GO:0030261 41 0.070
mitotic recombination GO:0006312 2 0.069
programmed cell death GO:0012501 257 0.066
meiotic spindle organization GO:0000212 36 0.063
microtubule based movement GO:0007018 51 0.063
dna repair GO:0006281 54 0.063
cellular macromolecular complex assembly GO:0034622 153 0.062
dna amplification GO:0006277 11 0.062
regulation of mitotic spindle organization GO:0060236 9 0.058
regulation of cell cycle process GO:0010564 181 0.057
regulation of cell division GO:0051302 72 0.057
negative regulation of transcription dna templated GO:0045892 237 0.054
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.054
lateral inhibition GO:0046331 206 0.051
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.051
regulation of cell cycle GO:0051726 291 0.051
metaphase anaphase transition of cell cycle GO:0044784 28 0.049
catabolic process GO:0009056 409 0.047
dna duplex unwinding GO:0032508 16 0.045
regulation of protein complex disassembly GO:0043244 29 0.043
cellular protein localization GO:0034613 160 0.043
dna damage checkpoint GO:0000077 78 0.042
negative regulation of rna metabolic process GO:0051253 251 0.041
dna biosynthetic process GO:0071897 24 0.039
mitotic cell cycle phase transition GO:0044772 138 0.039
death GO:0016265 284 0.039
organonitrogen compound metabolic process GO:1901564 318 0.038
regulation of cytoskeleton organization GO:0051493 89 0.038
double strand break repair GO:0006302 26 0.036
negative regulation of microtubule depolymerization GO:0007026 21 0.036
single organism cellular localization GO:1902580 180 0.036
meiotic chromosome condensation GO:0010032 3 0.036
chromosome separation GO:0051304 42 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
cellular protein modification process GO:0006464 438 0.034
regulation of chromosome segregation GO:0051983 32 0.034
regulation of mitotic cell cycle phase transition GO:1901990 130 0.034
regulation of protein depolymerization GO:1901879 27 0.034
neural precursor cell proliferation GO:0061351 75 0.033
regulation of mitotic sister chromatid separation GO:0010965 28 0.033
organic substance catabolic process GO:1901575 308 0.033
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.033
positive regulation of cdc42 gtpase activity GO:0043089 2 0.032
regulation of dendrite development GO:0050773 37 0.032
spindle assembly GO:0051225 80 0.032
cell proliferation GO:0008283 299 0.032
regulation of proteasomal protein catabolic process GO:0061136 39 0.031
karyosome formation GO:0030717 22 0.031
protein localization GO:0008104 284 0.031
distributive segregation GO:0032837 6 0.031
gene silencing GO:0016458 138 0.030
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.030
negative regulation of protein depolymerization GO:1901880 23 0.030
maintenance of protein location in cell GO:0032507 26 0.029
regulation of cell death GO:0010941 173 0.028
cell fate determination GO:0001709 91 0.028
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.028
ubiquitin dependent protein catabolic process GO:0006511 78 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.028
centrosome separation GO:0051299 20 0.027
regulation of gene expression epigenetic GO:0040029 128 0.027
regulation of localization GO:0032879 275 0.027
regulation of microtubule cytoskeleton organization GO:0070507 41 0.026
regulation of multicellular organismal development GO:2000026 414 0.026
negative regulation of biosynthetic process GO:0009890 277 0.026
meiotic cytokinesis GO:0033206 33 0.025
protein depolymerization GO:0051261 31 0.025
cytokinesis GO:0000910 90 0.025
male meiosis GO:0007140 52 0.025
negative regulation of cell death GO:0060548 81 0.025
negative regulation of cytoskeleton organization GO:0051494 30 0.025
regulation of microtubule depolymerization GO:0031114 24 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
negative regulation of protein complex disassembly GO:0043242 23 0.024
dna recombination GO:0006310 32 0.023
positive regulation of cell cycle process GO:0090068 28 0.023
ovarian fusome organization GO:0030723 11 0.023
eye development GO:0001654 323 0.023
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.023
negative regulation of rna biosynthetic process GO:1902679 240 0.023
regulation of cell cycle phase transition GO:1901987 130 0.023
negative regulation of signaling GO:0023057 219 0.022
aromatic compound catabolic process GO:0019439 166 0.022
cell cycle checkpoint GO:0000075 95 0.022
positive regulation of hydrolase activity GO:0051345 78 0.022
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.021
positive regulation of neurogenesis GO:0050769 41 0.021
regulation of spindle organization GO:0090224 17 0.021
open tracheal system development GO:0007424 204 0.021
single organism catabolic process GO:0044712 228 0.021
ribonucleoside metabolic process GO:0009119 127 0.021
dendrite development GO:0016358 204 0.021
chromatin modification GO:0016568 147 0.020
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.020
response to external biotic stimulus GO:0043207 293 0.020
regulation of gene silencing GO:0060968 63 0.020
response to light stimulus GO:0009416 124 0.020
response to abiotic stimulus GO:0009628 341 0.020
microtubule polymerization or depolymerization GO:0031109 39 0.020
regulation of mitotic sister chromatid segregation GO:0033047 28 0.020
cellular amino acid metabolic process GO:0006520 61 0.019
negative regulation of apoptotic process GO:0043066 63 0.019
anatomical structure homeostasis GO:0060249 97 0.019
regulation of molecular function GO:0065009 217 0.019
telomere capping GO:0016233 11 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
body morphogenesis GO:0010171 2 0.019
regulation of mitotic spindle elongation GO:0032888 1 0.018
endomembrane system organization GO:0010256 119 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
positive regulation of mitotic cell cycle GO:0045931 34 0.018
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
establishment or maintenance of cell polarity GO:0007163 167 0.018
positive regulation of protein complex assembly GO:0031334 22 0.018
proteolysis GO:0006508 192 0.017
dna integrity checkpoint GO:0031570 81 0.017
nucleotide metabolic process GO:0009117 161 0.017
establishment of spindle orientation GO:0051294 18 0.017
mitotic cell cycle checkpoint GO:0007093 88 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
sex differentiation GO:0007548 81 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
organic substance transport GO:0071702 257 0.016
gliogenesis GO:0042063 80 0.016
protein transport GO:0015031 155 0.016
positive regulation of catabolic process GO:0009896 105 0.016
cellular catabolic process GO:0044248 372 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
positive regulation of developmental process GO:0051094 143 0.015
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
positive regulation of cell cycle GO:0045787 43 0.014
regulation of microtubule based process GO:0032886 49 0.014
neuron recognition GO:0008038 101 0.014
homeostatic process GO:0042592 199 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
positive regulation of cell communication GO:0010647 250 0.014
chromatin silencing GO:0006342 76 0.014
heterocycle catabolic process GO:0046700 166 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
protein phosphorylation GO:0006468 169 0.014
chromatin organization GO:0006325 207 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
maintenance of protein location GO:0045185 28 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
respiratory system development GO:0060541 213 0.013
cellular protein catabolic process GO:0044257 83 0.013
ras protein signal transduction GO:0007265 88 0.013
reproductive structure development GO:0048608 74 0.013
intracellular signal transduction GO:0035556 300 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
protein polymerization GO:0051258 42 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
regulation of dna metabolic process GO:0051052 34 0.013
maintenance of location GO:0051235 73 0.013
g2 dna damage checkpoint GO:0031572 69 0.013
snrna processing GO:0016180 14 0.013
maintenance of location in cell GO:0051651 28 0.013
actomyosin contractile ring contraction GO:0000916 12 0.012
mitotic dna damage checkpoint GO:0044773 74 0.012
axonogenesis GO:0007409 290 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.012
endocytosis GO:0006897 310 0.012
small molecule metabolic process GO:0044281 305 0.012
regulation of protein metabolic process GO:0051246 256 0.012
mitotic dna integrity checkpoint GO:0044774 75 0.012
response to biotic stimulus GO:0009607 294 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
regulation of chromatin silencing GO:0031935 36 0.012
oxoacid metabolic process GO:0043436 103 0.011
apoptotic process GO:0006915 159 0.011
cellular protein complex disassembly GO:0043624 35 0.011
polarity specification of dorsal ventral axis GO:0009951 6 0.011
eye morphogenesis GO:0048592 260 0.011
asymmetric stem cell division GO:0098722 49 0.011
female meiosis chromosome segregation GO:0016321 33 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
antimicrobial humoral response GO:0019730 99 0.011
regulation of organelle organization GO:0033043 196 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
cytoskeleton dependent intracellular transport GO:0030705 44 0.011
cell death GO:0008219 279 0.011
positive regulation of organelle organization GO:0010638 65 0.010
rho protein signal transduction GO:0007266 14 0.010
regulation of catalytic activity GO:0050790 185 0.010
fusome organization GO:0045478 13 0.010
salivary gland cell autophagic cell death GO:0035071 83 0.010
positive regulation of protein metabolic process GO:0051247 128 0.010
regulation of programmed cell death GO:0043067 152 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010

Ndc80 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011