Drosophila melanogaster

65 known processes

unpg (Dmel_CG1650)

unplugged

(Aliases: unp,Dmel\CG1650,anon-45C,CG1650,upg,Gbx)

unpg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transcription dna templated GO:0045893 266 0.059
Fly
negative regulation of response to stimulus GO:0048585 258 0.058
positive regulation of rna biosynthetic process GO:1902680 266 0.056
Fly
sensory organ morphogenesis GO:0090596 260 0.055
Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.054
Fly
neuron projection guidance GO:0097485 241 0.051
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.050
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.050
Fly
chemotaxis GO:0006935 249 0.049
Mouse
tube development GO:0035295 244 0.048
Zebrafish Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.046
Fly
cell death GO:0008219 279 0.045
body morphogenesis GO:0010171 2 0.043
positive regulation of rna metabolic process GO:0051254 271 0.043
Fly
locomotory behavior GO:0007626 176 0.043
Mouse
positive regulation of biosynthetic process GO:0009891 316 0.043
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.042
Fly
compound eye morphogenesis GO:0001745 249 0.042
Fly
respiratory system development GO:0060541 213 0.041
taxis GO:0042330 304 0.041
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.041
Fly
eye development GO:0001654 323 0.040
Fly
regulation of multicellular organismal development GO:2000026 414 0.040
regionalization GO:0003002 416 0.040
Zebrafish Mouse
kidney development GO:0001822 3 0.038
cell proliferation GO:0008283 299 0.038
Mouse
neuron fate commitment GO:0048663 50 0.038
Mouse Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.037
Fly
cell migration GO:0016477 238 0.037
Mouse
establishment of localization in cell GO:0051649 402 0.036
death GO:0016265 284 0.036
morphogenesis of an epithelium GO:0002009 276 0.035
Mouse Fly
protein localization GO:0008104 284 0.035
photoreceptor cell differentiation GO:0046530 170 0.035
Fly
axon development GO:0061564 297 0.035
Mouse Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.034
Fly
negative regulation of transcription dna templated GO:0045892 237 0.034
Fly
single organism behavior GO:0044708 391 0.033
Mouse
segmentation GO:0035282 207 0.033
negative regulation of cellular biosynthetic process GO:0031327 277 0.033
Fly
axonogenesis GO:0007409 290 0.032
Mouse Fly
axon guidance GO:0007411 233 0.031
Mouse
embryonic pattern specification GO:0009880 174 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.031
Fly
programmed cell death GO:0012501 257 0.031
negative regulation of cellular metabolic process GO:0031324 382 0.031
Fly
regulation of anatomical structure morphogenesis GO:0022603 242 0.030
Zebrafish
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.029
Fly
organonitrogen compound metabolic process GO:1901564 318 0.029
notch signaling pathway GO:0007219 120 0.029
negative regulation of rna metabolic process GO:0051253 251 0.028
Fly
compound eye development GO:0048749 307 0.028
Fly
response to abiotic stimulus GO:0009628 341 0.028
establishment or maintenance of cell polarity GO:0007163 167 0.028
Fly
regulation of intracellular signal transduction GO:1902531 236 0.028
negative regulation of biosynthetic process GO:0009890 277 0.027
Fly
single organism cellular localization GO:1902580 180 0.027
dendrite morphogenesis GO:0048813 199 0.027
regulation of cell cycle GO:0051726 291 0.027
regulation of notch signaling pathway GO:0008593 100 0.026
digestive tract morphogenesis GO:0048546 127 0.026
negative regulation of gene expression GO:0010629 387 0.026
Fly
localization of cell GO:0051674 257 0.026
Mouse
digestive tract development GO:0048565 149 0.025
regulation of localization GO:0032879 275 0.025
response to organic substance GO:0010033 284 0.025
cellular protein modification process GO:0006464 438 0.025
cell motility GO:0048870 251 0.025
Mouse
positive regulation of gene expression GO:0010628 290 0.025
Fly
intracellular transport GO:0046907 228 0.024
telencephalon development GO:0021537 2 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
defense response GO:0006952 300 0.024
compound eye photoreceptor cell differentiation GO:0001751 140 0.024
Fly
protein modification process GO:0036211 438 0.024
negative regulation of rna biosynthetic process GO:1902679 240 0.023
Fly
blastoderm segmentation GO:0007350 159 0.023
chromosome organization GO:0051276 360 0.023
cell fate specification GO:0001708 71 0.023
regulation of cell proliferation GO:0042127 163 0.023
regulation of cell death GO:0010941 173 0.023
regulation of cell differentiation GO:0045595 302 0.023
camera type eye development GO:0043010 4 0.023
lateral inhibition GO:0046331 206 0.023
Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.022
Fly
response to external biotic stimulus GO:0043207 293 0.022
response to other organism GO:0051707 293 0.022
negative regulation of signal transduction GO:0009968 206 0.022
forebrain development GO:0030900 2 0.022
Mouse
open tracheal system development GO:0007424 204 0.022
homeostatic process GO:0042592 199 0.022
regulation of organelle organization GO:0033043 196 0.022
digestive system development GO:0055123 149 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
Fly
immune system process GO:0002376 347 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
connective tissue development GO:0061448 3 0.021
imaginal disc pattern formation GO:0007447 91 0.020
organic substance transport GO:0071702 257 0.020
phosphorylation GO:0016310 294 0.020
appendage morphogenesis GO:0035107 397 0.020
circulatory system development GO:0072359 82 0.020
Mouse
organic acid metabolic process GO:0006082 103 0.020
gland morphogenesis GO:0022612 145 0.020
regulation of phosphorylation GO:0042325 147 0.020
protein transport GO:0015031 155 0.020
cellular macromolecule localization GO:0070727 220 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
Fly
establishment of protein localization GO:0045184 163 0.020
tube morphogenesis GO:0035239 191 0.019
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
Fly
central nervous system development GO:0007417 201 0.019
exocrine system development GO:0035272 162 0.019
immune response GO:0006955 246 0.019
mitotic nuclear division GO:0007067 213 0.019
gliogenesis GO:0042063 80 0.019
dna metabolic process GO:0006259 227 0.019
cell maturation GO:0048469 144 0.019
synaptic transmission GO:0007268 288 0.019
eye morphogenesis GO:0048592 260 0.019
Fly
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
embryonic axis specification GO:0000578 107 0.018
developmental growth GO:0048589 280 0.018
tissue morphogenesis GO:0048729 297 0.018
Mouse Fly
imaginal disc derived appendage development GO:0048737 399 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
head development GO:0060322 135 0.018
apoptotic process GO:0006915 159 0.018
cellularization GO:0007349 90 0.017
regulation of immune system process GO:0002682 176 0.017
regulation of synaptic transmission GO:0050804 69 0.017
positive regulation of cell communication GO:0010647 250 0.017
regulation of behavior GO:0050795 75 0.017
epithelial cell differentiation GO:0030855 322 0.017
Fly
intracellular signal transduction GO:0035556 300 0.017
regulation of mitotic cell cycle GO:0007346 190 0.017
axis specification GO:0009798 167 0.017
neurological system process GO:0050877 358 0.017
Mouse
nephron development GO:0072006 3 0.017
brain development GO:0007420 120 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
developmental maturation GO:0021700 172 0.017
organelle fission GO:0048285 340 0.016
regulation of cellular localization GO:0060341 136 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
regulation of response to external stimulus GO:0032101 115 0.016
salivary gland morphogenesis GO:0007435 145 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
compound eye photoreceptor fate commitment GO:0001752 36 0.016
Fly
compound eye photoreceptor development GO:0042051 78 0.016
malpighian tubule morphogenesis GO:0007443 44 0.016
rna processing GO:0006396 147 0.016
positive regulation of signaling GO:0023056 243 0.016
chromatin organization GO:0006325 207 0.016
renal tubule morphogenesis GO:0061333 44 0.016
single organism intracellular transport GO:1902582 207 0.016
anterior posterior axis specification embryo GO:0008595 103 0.016
nuclear division GO:0000280 332 0.016
regulation of apoptotic process GO:0042981 130 0.016
organic substance catabolic process GO:1901575 308 0.016
hindgut development GO:0061525 58 0.015
negative regulation of cell communication GO:0010648 223 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
oxoacid metabolic process GO:0043436 103 0.015
neuron recognition GO:0008038 101 0.015
catabolic process GO:0009056 409 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
dendrite development GO:0016358 204 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
appendage development GO:0048736 401 0.015
defense response to bacterium GO:0042742 178 0.015
urogenital system development GO:0001655 72 0.015
regulation of cell cycle process GO:0010564 181 0.015
rhythmic behavior GO:0007622 76 0.015
tripartite regional subdivision GO:0007351 103 0.015
photoreceptor cell fate commitment GO:0046552 41 0.015
Fly
immune effector process GO:0002252 98 0.014
growth GO:0040007 359 0.014
oocyte axis specification GO:0007309 108 0.014
cell fate determination GO:0001709 91 0.014
regulation of developmental growth GO:0048638 174 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
Fly
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.014
anterior posterior axis specification GO:0009948 109 0.014
mrna metabolic process GO:0016071 124 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
Fly
phagocytosis GO:0006909 215 0.014
positive regulation of developmental process GO:0051094 143 0.014
regulation of programmed cell death GO:0043067 152 0.014
anterior posterior pattern specification GO:0009952 136 0.014
Zebrafish Mouse
wound healing GO:0042060 75 0.014
hindbrain development GO:0030902 2 0.014
Zebrafish Mouse
gland development GO:0048732 191 0.014
hindgut morphogenesis GO:0007442 58 0.014
response to biotic stimulus GO:0009607 294 0.014
spermatid development GO:0007286 98 0.014
oocyte construction GO:0007308 112 0.014
actin cytoskeleton organization GO:0030036 206 0.014
ovarian follicle cell development GO:0030707 248 0.014
salivary gland development GO:0007431 162 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
organelle assembly GO:0070925 198 0.013
eye photoreceptor cell development GO:0042462 81 0.013
immune response activating signal transduction GO:0002757 2 0.013
eye antennal disc development GO:0035214 60 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
Fly
eye photoreceptor cell fate commitment GO:0042706 37 0.013
Fly
response to wounding GO:0009611 94 0.013
mapk cascade GO:0000165 107 0.013
regulation of growth GO:0040008 233 0.013
negative regulation of cell death GO:0060548 81 0.013
epithelial cell development GO:0002064 274 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
spindle organization GO:0007051 253 0.013
negative regulation of developmental process GO:0051093 201 0.013
positive regulation of cell motility GO:2000147 3 0.013
sensory perception GO:0007600 196 0.013
Mouse
stem cell proliferation GO:0072089 88 0.013
chromatin modification GO:0016568 147 0.013
reproductive behavior GO:0019098 122 0.013
negative regulation of signaling GO:0023057 219 0.012
gene silencing GO:0016458 138 0.012
spermatid differentiation GO:0048515 114 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
cytoplasm organization GO:0007028 64 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
Mouse
embryonic hindgut morphogenesis GO:0048619 48 0.012
response to oxygen containing compound GO:1901700 200 0.012
embryonic morphogenesis GO:0048598 206 0.012
Zebrafish Mouse
cellular response to oxygen containing compound GO:1901701 79 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
sensory perception of pain GO:0019233 4 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
photoreceptor cell development GO:0042461 96 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
positive regulation of cell migration GO:0030335 2 0.012
mitotic spindle organization GO:0007052 220 0.012
dorsal ventral axis specification GO:0009950 66 0.012
regulation of nervous system development GO:0051960 248 0.012
regulation of rna splicing GO:0043484 69 0.012
malpighian tubule development GO:0072002 64 0.012
innate immune response GO:0045087 144 0.012
neuroblast proliferation GO:0007405 74 0.012
spermatogenesis GO:0007283 200 0.012
regulation of embryonic development GO:0045995 68 0.012
Zebrafish
muscle structure development GO:0061061 224 0.012
chaeta morphogenesis GO:0008407 42 0.012
regulation of protein localization GO:0032880 76 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.011
histolysis GO:0007559 102 0.011
positive regulation of signal transduction GO:0009967 223 0.011
neural precursor cell proliferation GO:0061351 75 0.011
Mouse
small molecule metabolic process GO:0044281 305 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
monocarboxylic acid transport GO:0015718 3 0.011
regulation of response to stress GO:0080134 200 0.011
cuticle development GO:0042335 86 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
cellular catabolic process GO:0044248 372 0.011
amine metabolic process GO:0009308 12 0.011
macromolecular complex assembly GO:0065003 256 0.011
mesenchymal cell development GO:0014031 1 0.011
Mouse
oocyte anterior posterior axis specification GO:0007314 72 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
mrna processing GO:0006397 104 0.011
stem cell differentiation GO:0048863 117 0.011
Mouse
oocyte differentiation GO:0009994 145 0.011
cation transport GO:0006812 110 0.011
synapse organization GO:0050808 196 0.011
retina development in camera type eye GO:0060041 4 0.011
camera type eye morphogenesis GO:0048593 2 0.011
cellular amine metabolic process GO:0044106 12 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of cell development GO:0060284 215 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
cellular protein localization GO:0034613 160 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
Fly
cell division GO:0051301 248 0.011
pole plasm rna localization GO:0007316 52 0.011
regulation of mapk cascade GO:0043408 92 0.011
peptide metabolic process GO:0006518 80 0.011
embryonic organ development GO:0048568 50 0.011
Mouse
cell recognition GO:0008037 102 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
epithelial cell migration GO:0010631 148 0.011
segment specification GO:0007379 33 0.010
endomembrane system organization GO:0010256 119 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
dna packaging GO:0006323 91 0.010
leg disc development GO:0035218 92 0.010
pole plasm oskar mrna localization GO:0045451 46 0.010
response to lipopolysaccharide GO:0032496 4 0.010
endodermal cell differentiation GO:0035987 3 0.010
regulation of neuron differentiation GO:0045664 103 0.010
single organism membrane organization GO:0044802 93 0.010
renal tubule development GO:0061326 64 0.010
regulation of mrna splicing via spliceosome GO:0048024 64 0.010
cell projection assembly GO:0030031 94 0.010
mrna splicing via spliceosome GO:0000398 73 0.010
activation of innate immune response GO:0002218 4 0.010
intracellular mrna localization GO:0008298 66 0.010
maternal determination of anterior posterior axis embryo GO:0008358 74 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.010

unpg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
kidney disease DOID:557 0 0.014
urinary system disease DOID:18 0 0.014
disease of metabolism DOID:0014667 0 0.012
amyloidosis DOID:9120 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
familial visceral amyloidosis DOID:0050636 0 0.012