Drosophila melanogaster

119 known processes

HLHmgamma (Dmel_CG8333)

E(spl) region transcript mgamma

(Aliases: CG8333,mB,Mgamma,E(spl)gamma,e(spl)mgamma,E(spl)-mgamma,E(Spl) HLH-m gamma,HLH-mgamma,Dmel\CG8333,E(spl) mgamma,Dm-mB,clone 1.49,HLHmB,bHLHb34,E(spl) m gamma,E(spl)mB,anon-EST:Liang-1.49,E(spl)mgamma,mgamma,E(spl)Mgamma)

HLHmgamma biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ precursor cell fate determination GO:0016360 19 1.000
Fly
cell fate determination involved in pattern specification GO:0060582 19 1.000
Fly
neuron fate determination GO:0048664 1 0.998
Mouse
formation of organ boundary GO:0010160 30 0.998
Fly
sensory organ boundary specification GO:0008052 22 0.996
Fly
glial cell fate commitment GO:0021781 3 0.991
Mouse
stem cell maintenance GO:0019827 67 0.986
Human Mouse Rat
regulation of neural precursor cell proliferation GO:2000177 35 0.977
cell fate commitment involved in pattern specification GO:0060581 31 0.975
Fly
notch signaling pathway GO:0007219 120 0.974
Human Zebrafish Mouse Fly
axon ensheathment in central nervous system GO:0032291 3 0.972
Mouse
r1 r6 cell differentiation GO:0048052 4 0.970
Fly
r7 cell differentiation GO:0045466 43 0.966
Fly
positive regulation of bmp signaling pathway GO:0030513 5 0.959
Mouse
formation of anatomical boundary GO:0048859 37 0.952
Fly
regulation of neuroblast proliferation GO:1902692 34 0.942
sex determination GO:0007530 18 0.932
Fly
nephron epithelium morphogenesis GO:0072088 3 0.932
Mouse
regulation of timing of cell differentiation GO:0048505 1 0.913
Mouse
tyrosine phosphorylation of stat protein GO:0007260 1 0.909
Mouse
negative regulation of gliogenesis GO:0014014 6 0.892
Mouse
regulation of glial cell differentiation GO:0045685 1 0.890
Mouse
cell fate specification GO:0001708 71 0.890
Worm
stem cell proliferation GO:0072089 88 0.889
organ formation GO:0048645 39 0.887
Fly
dosage compensation GO:0007549 16 0.882
Fly
neural precursor cell proliferation GO:0061351 75 0.870
regulation of gliogenesis GO:0014013 11 0.865
Mouse
malpighian tubule morphogenesis GO:0007443 44 0.863
cell maturation GO:0048469 144 0.860
Mouse
cell division GO:0051301 248 0.857
Fly
neuroblast proliferation GO:0007405 74 0.856
regulation of stem cell proliferation GO:0072091 40 0.855
renal system development GO:0072001 72 0.853
Mouse
sex determination establishment of x a ratio GO:0007540 1 0.841
Fly
regulation of mitosis GO:0007088 56 0.834
Fly
glial cell development GO:0021782 27 0.822
Mouse
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.822
renal tubule morphogenesis GO:0061333 44 0.822
Mouse
nuclear division GO:0000280 332 0.817
Fly
renal tubule development GO:0061326 64 0.810
Mouse
somatic sex determination GO:0018993 2 0.808
Fly
primary sex determination soma GO:0007539 2 0.807
Fly
neuronal stem cell maintenance GO:0097150 4 0.802
Human Mouse Rat
glial cell differentiation GO:0010001 35 0.802
Mouse Rat
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.799
regionalization GO:0003002 416 0.798
regulation of notch signaling pathway GO:0008593 100 0.795
Mouse
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.773
Mouse
single organism behavior GO:0044708 391 0.771
Fly
gliogenesis GO:0042063 80 0.764
Zebrafish Mouse Rat
negative regulation of stem cell differentiation GO:2000737 8 0.764
Human
mitotic nuclear division GO:0007067 213 0.755
Fly
cell fate determination GO:0001709 91 0.730
Mouse Fly
regulation of cell differentiation GO:0045595 302 0.710
chaeta morphogenesis GO:0008407 42 0.708
nephron tubule development GO:0072080 3 0.705
Mouse
organelle fission GO:0048285 340 0.699
Fly
regulation of mitotic cell cycle GO:0007346 190 0.694
Fly
respiratory system development GO:0060541 213 0.690
Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.689
nephron tubule formation GO:0072079 3 0.684
Mouse
nerve development GO:0021675 6 0.683
Mouse
axon development GO:0061564 297 0.680
Zebrafish
positive regulation of stem cell proliferation GO:2000648 8 0.679
embryonic epithelial tube formation GO:0001838 6 0.672
Mouse
positive regulation of nervous system development GO:0051962 69 0.670
positive regulation of mitotic cell cycle GO:0045931 34 0.664
Fly
positive regulation of neural precursor cell proliferation GO:2000179 8 0.662
negative regulation of cell development GO:0010721 62 0.656
Zebrafish Mouse Rat
hair cell differentiation GO:0035315 47 0.644
Mouse
tube formation GO:0035148 21 0.644
Mouse
neuroblast fate specification GO:0014018 2 0.639
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.639
Zebrafish
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.634
Mouse
stem cell differentiation GO:0048863 117 0.630
Human Mouse Rat
developmental maturation GO:0021700 172 0.627
Mouse
nephron epithelium development GO:0072009 3 0.611
Mouse
axon ensheathment GO:0008366 10 0.605
Mouse
embryonic hindgut morphogenesis GO:0048619 48 0.601
epithelial tube formation GO:0072175 7 0.588
Mouse
nephron tubule morphogenesis GO:0072078 3 0.580
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.578
negative regulation of nervous system development GO:0051961 92 0.571
Zebrafish Mouse Rat
regulation of cell cycle GO:0051726 291 0.567
Zebrafish Fly
nephron morphogenesis GO:0072028 3 0.559
Mouse
cranial nerve development GO:0021545 1 0.555
Mouse
regulation of nervous system development GO:0051960 248 0.550
urogenital system development GO:0001655 72 0.547
Mouse
positive regulation of gene expression GO:0010628 290 0.547
Mouse
regulation of cell cycle process GO:0010564 181 0.546
Fly
regulation of nuclear division GO:0051783 58 0.536
Fly
regulation of neurogenesis GO:0050767 158 0.529
organic acid metabolic process GO:0006082 103 0.529
tissue morphogenesis GO:0048729 297 0.528
Mouse
larval behavior GO:0030537 42 0.526
Fly
positive regulation of biosynthetic process GO:0009891 316 0.526
Mouse
positive regulation of developmental process GO:0051094 143 0.524
regulation of gene expression epigenetic GO:0040029 128 0.524
Fly
kidney epithelium development GO:0072073 3 0.518
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.513
regulation of cellular amino acid metabolic process GO:0006521 0 0.513
connective tissue development GO:0061448 3 0.511
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.509
Mouse
hindbrain development GO:0030902 2 0.508
Mouse
tube morphogenesis GO:0035239 191 0.504
Mouse Fly
stem cell fate commitment GO:0048865 25 0.499
central nervous system development GO:0007417 201 0.498
Zebrafish Mouse Rat Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.484
forebrain development GO:0030900 2 0.483
Mouse Rat
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.482
negative regulation of transcription dna templated GO:0045892 237 0.482
regulation of response to stress GO:0080134 200 0.474
Fly
intracellular signal transduction GO:0035556 300 0.473
Mouse
stem cell fate specification GO:0048866 2 0.472
compound eye photoreceptor cell differentiation GO:0001751 140 0.470
Fly
negative regulation of neurogenesis GO:0050768 53 0.470
Zebrafish Mouse Rat
regulation of multicellular organismal development GO:2000026 414 0.467
axonogenesis GO:0007409 290 0.464
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 405 0.461
Zebrafish Mouse
regulation of bmp signaling pathway GO:0030510 23 0.453
Mouse
stem cell development GO:0048864 79 0.452
Human Mouse Rat
immune system process GO:0002376 347 0.449
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.448
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.445
Mouse
anterior posterior pattern specification GO:0009952 136 0.441
Zebrafish Mouse Worm
head development GO:0060322 135 0.441
Zebrafish Mouse Rat Fly
nephron development GO:0072006 3 0.441
Mouse
telencephalon development GO:0021537 2 0.440
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.439
response to abiotic stimulus GO:0009628 341 0.438
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.438
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.436
Mouse
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.434
Rat
kidney development GO:0001822 3 0.433
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.432
epidermal cell differentiation GO:0009913 51 0.430
Mouse Worm
regulation of cellular ketone metabolic process GO:0010565 3 0.425
positive regulation of nucleic acid templated transcription GO:1903508 266 0.418
Mouse
adult behavior GO:0030534 137 0.413
Fly
positive regulation of response to stimulus GO:0048584 323 0.408
Mouse
bmp signaling pathway GO:0030509 27 0.406
Mouse
regulation of organelle organization GO:0033043 196 0.404
Fly
organonitrogen compound metabolic process GO:1901564 318 0.401
positive regulation of rna biosynthetic process GO:1902680 266 0.399
Mouse
dorsal ventral pattern formation GO:0009953 133 0.395
peptidyl tyrosine phosphorylation GO:0018108 24 0.391
Mouse
regulation of cellular response to stress GO:0080135 89 0.391
Fly
locomotory behavior GO:0007626 176 0.389
Fly
hindgut morphogenesis GO:0007442 58 0.389
dendrite morphogenesis GO:0048813 199 0.385
Fly
gland development GO:0048732 191 0.383
Fly
negative regulation of notch signaling pathway GO:0045746 41 0.377
regulation of stem cell differentiation GO:2000736 14 0.370
Human
startle response GO:0001964 16 0.370
Fly
positive regulation of signaling GO:0023056 243 0.362
Mouse
positive regulation of neuroblast proliferation GO:0002052 7 0.361
eye photoreceptor cell differentiation GO:0001754 145 0.360
Fly
mesoderm development GO:0007498 78 0.359
Fly
cell proliferation GO:0008283 299 0.358
regulation of neuron differentiation GO:0045664 103 0.357
Mouse Rat
negative regulation of rna biosynthetic process GO:1902679 240 0.353
regulation of cell development GO:0060284 215 0.350
positive regulation of neurogenesis GO:0050769 41 0.350
regulation of cellular amine metabolic process GO:0033238 3 0.350
kidney morphogenesis GO:0060993 3 0.348
Mouse
sensory organ morphogenesis GO:0090596 260 0.348
Fly
ensheathment of neurons GO:0007272 10 0.347
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.343
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.342
Zebrafish
photoreceptor cell differentiation GO:0046530 170 0.341
Fly
dendrite development GO:0016358 204 0.335
Fly
cellular ketone metabolic process GO:0042180 24 0.333
rhythmic process GO:0048511 106 0.330
Mouse
oxoacid metabolic process GO:0043436 103 0.327
positive regulation of cell communication GO:0010647 250 0.326
Mouse
segmentation GO:0035282 207 0.324
Zebrafish Mouse
developmental cell growth GO:0048588 52 0.320
segment specification GO:0007379 33 0.319
Zebrafish Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.316
carboxylic acid metabolic process GO:0019752 92 0.310
peptide metabolic process GO:0006518 80 0.308
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.308
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.307
regulation of cell division GO:0051302 72 0.306
Fly
positive regulation of rna metabolic process GO:0051254 271 0.304
Mouse
regulation of response to dna damage stimulus GO:2001020 23 0.302
Fly
positive regulation of signal transduction GO:0009967 223 0.302
Mouse
compound eye morphogenesis GO:0001745 249 0.301
Fly
camera type eye development GO:0043010 4 0.300
Mouse
regulation of immune system process GO:0002682 176 0.299
Rat
negative regulation of glial cell proliferation GO:0060253 6 0.296
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.294
Mouse
cellular amine metabolic process GO:0044106 12 0.289
positive regulation of protein metabolic process GO:0051247 128 0.286
Zebrafish Mouse
peripheral nervous system neuron development GO:0048935 8 0.286
Zebrafish
proximal distal pattern formation GO:0009954 15 0.285
Mouse
morphogenesis of an epithelium GO:0002009 276 0.284
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.284
brain development GO:0007420 120 0.282
Zebrafish Mouse Rat Fly
small molecule metabolic process GO:0044281 305 0.281
neuron fate commitment GO:0048663 50 0.280
Mouse
eye morphogenesis GO:0048592 260 0.278
Fly
axon extension involved in axon guidance GO:0048846 10 0.277
salivary gland development GO:0007431 162 0.275
Fly
transmission of nerve impulse GO:0019226 12 0.274
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.273
Mouse
peptidyl tyrosine modification GO:0018212 24 0.267
Mouse
neuroepithelial cell differentiation GO:0060563 6 0.266
epidermis development GO:0008544 65 0.262
Mouse Worm
regulation of intracellular signal transduction GO:1902531 236 0.261
Mouse
regulation of neuron projection development GO:0010975 69 0.260
adult locomotory behavior GO:0008344 76 0.260
Fly
regulation of cell morphogenesis GO:0022604 163 0.258
positive regulation of notch signaling pathway GO:0045747 34 0.246
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.245
cellular amide metabolic process GO:0043603 80 0.244
regulation of membrane potential GO:0042391 35 0.240
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.240
Mouse
negative regulation of developmental process GO:0051093 201 0.239
Human Zebrafish Mouse Rat
open tracheal system development GO:0007424 204 0.238
Fly
imaginal disc pattern formation GO:0007447 91 0.238
positive regulation of cellular protein metabolic process GO:0032270 118 0.238
Zebrafish Mouse
positive regulation of cell cycle GO:0045787 43 0.236
Zebrafish Fly
negative regulation of biosynthetic process GO:0009890 277 0.235
negative regulation of multicellular organismal process GO:0051241 142 0.234
Zebrafish Mouse Rat
regulation of glial cell proliferation GO:0060251 11 0.233
positive regulation of cellular component organization GO:0051130 156 0.231
Fly
gland morphogenesis GO:0022612 145 0.231
Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.229
positive regulation of phosphate metabolic process GO:0045937 139 0.228
Zebrafish Mouse
tube development GO:0035295 244 0.227
Zebrafish Mouse Fly
humoral immune response GO:0006959 117 0.226
wing disc pattern formation GO:0035222 66 0.226
morphogenesis of embryonic epithelium GO:0016331 94 0.225
Mouse
peripheral nervous system development GO:0007422 52 0.223
Zebrafish
malpighian tubule development GO:0072002 64 0.216
positive regulation of cell proliferation GO:0008284 47 0.214
neuron fate specification GO:0048665 12 0.213
negative regulation of gene expression GO:0010629 387 0.213
regulation of axon extension GO:0030516 8 0.212
embryonic morphogenesis GO:0048598 206 0.212
Zebrafish Mouse
eye development GO:0001654 323 0.210
Zebrafish Mouse Fly
cellular amino acid metabolic process GO:0006520 61 0.205
positive regulation of cell differentiation GO:0045597 64 0.204
regulation of phosphorylation GO:0042325 147 0.201
Zebrafish Mouse
macromolecular complex assembly GO:0065003 256 0.198
Mouse
smoothened signaling pathway GO:0007224 49 0.196
Mouse
regulation of axon extension involved in axon guidance GO:0048841 4 0.194
negative regulation of cell differentiation GO:0045596 143 0.194
Human Zebrafish Mouse Rat
regulation of epithelial cell differentiation GO:0030856 4 0.193
compound eye development GO:0048749 307 0.191
Fly
neuron projection guidance GO:0097485 241 0.191
protein modification process GO:0036211 438 0.191
Zebrafish Mouse
cellular protein modification process GO:0006464 438 0.187
Zebrafish Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.187
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.187
peptidyl amino acid modification GO:0018193 105 0.184
Mouse
positive regulation of cell development GO:0010720 61 0.182
hindgut development GO:0061525 58 0.182
protein complex biogenesis GO:0070271 201 0.182
Mouse
jak stat cascade GO:0007259 49 0.181
Mouse
regulation of protein modification process GO:0031399 112 0.181
Zebrafish Mouse
larval locomotory behavior GO:0008345 27 0.180
Fly
spinal cord patterning GO:0021511 1 0.179
response to other organism GO:0051707 293 0.178
neuron projection extension GO:1990138 32 0.178
epithelial cell differentiation GO:0030855 322 0.178
Mouse Worm
regulation of protein metabolic process GO:0051246 256 0.176
Zebrafish Mouse
response to hypoxia GO:0001666 53 0.174
Fly
neuromuscular process GO:0050905 21 0.174
Fly
immune response GO:0006955 246 0.173
glial cell proliferation GO:0014009 13 0.172
spinal cord development GO:0021510 1 0.171
cellular response to dna damage stimulus GO:0006974 223 0.164
Fly
skin development GO:0043588 65 0.164
Mouse Worm
positive regulation of cell cycle process GO:0090068 28 0.163
Fly
biological adhesion GO:0022610 138 0.162
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.159
neuroblast fate commitment GO:0014017 19 0.155
neuronal action potential GO:0019228 10 0.152
Mouse
positive regulation of protein kinase activity GO:0045860 25 0.151
Zebrafish
hematopoietic progenitor cell differentiation GO:0002244 1 0.151
Rat
protein complex assembly GO:0006461 200 0.151
Mouse
regulation of oviposition GO:0046662 14 0.149
bolwig s organ development GO:0055034 8 0.146
neurological system process GO:0050877 358 0.145
Mouse Fly
regulation of protein kinase activity GO:0045859 51 0.143
Zebrafish
positive regulation of molecular function GO:0044093 136 0.143
Zebrafish
positive regulation of intracellular signal transduction GO:1902533 116 0.142
Mouse
central nervous system neuron differentiation GO:0021953 8 0.142
Rat
multi organism reproductive behavior GO:0044705 121 0.142
malpighian tubule tip cell differentiation GO:0061382 9 0.140
response to external biotic stimulus GO:0043207 293 0.140
positive regulation of transferase activity GO:0051347 26 0.140
Zebrafish
neuroblast differentiation GO:0014016 29 0.139
digestive tract morphogenesis GO:0048546 127 0.137
response to decreased oxygen levels GO:0036293 58 0.137
Fly
regulation of axonogenesis GO:0050770 32 0.137
phosphorylation GO:0016310 294 0.136
Zebrafish Mouse
brain morphogenesis GO:0048854 16 0.133
Fly
amine metabolic process GO:0009308 12 0.129
action potential GO:0001508 13 0.127
Mouse
protein phosphorylation GO:0006468 169 0.127
Zebrafish Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.125
response to biotic stimulus GO:0009607 294 0.125
regulation of axon guidance GO:1902667 10 0.125
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.124
regulation of cell proliferation GO:0042127 163 0.122
chaeta development GO:0022416 97 0.122
positive regulation of phosphorylation GO:0042327 87 0.119
Zebrafish Mouse
spinal cord dorsal ventral patterning GO:0021513 1 0.118
wing disc dorsal ventral pattern formation GO:0048190 47 0.118
cell migration GO:0016477 238 0.118
salivary gland morphogenesis GO:0007435 145 0.118
Fly
enzyme linked receptor protein signaling pathway GO:0007167 179 0.116
Mouse
epithelial cell proliferation GO:0050673 15 0.115
hemopoiesis GO:0030097 46 0.115
Rat
response to organic substance GO:0010033 284 0.113
regulation of kinase activity GO:0043549 53 0.112
Zebrafish
regulation of phosphate metabolic process GO:0019220 210 0.112
Zebrafish Mouse
positive regulation of protein phosphorylation GO:0001934 34 0.110
Zebrafish Mouse
negative regulation of immune system process GO:0002683 50 0.110
Rat
regulation of cellular amide metabolic process GO:0034248 39 0.110
negative regulation of cell cycle process GO:0010948 109 0.109
positive regulation of programmed cell death GO:0043068 62 0.109
body morphogenesis GO:0010171 2 0.107
glandular epithelial cell differentiation GO:0002067 1 0.107
response to oxygen levels GO:0070482 59 0.106
Fly
epithelial tube morphogenesis GO:0060562 88 0.104
Mouse
positive regulation of kinase activity GO:0033674 25 0.104
Zebrafish
cell death GO:0008219 279 0.102
localization of cell GO:0051674 257 0.102
negative regulation of signaling GO:0023057 219 0.100
regulation of catalytic activity GO:0050790 185 0.100
Zebrafish
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.100
axon extension GO:0048675 32 0.099
positive regulation of catalytic activity GO:0043085 118 0.099
Zebrafish
regulation of reproductive process GO:2000241 54 0.098
cell adhesion GO:0007155 136 0.097
Mouse
medulla oblongata development GO:0021550 2 0.096
multicellular organismal signaling GO:0035637 12 0.094
Mouse
regulation of cellular protein metabolic process GO:0032268 243 0.092
Zebrafish Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.091
Zebrafish Mouse
antimicrobial peptide production GO:0002775 46 0.091
axon guidance GO:0007411 233 0.089
regulation of response to external stimulus GO:0032101 115 0.089
peripheral nervous system neuron differentiation GO:0048934 8 0.088
Zebrafish
negative regulation of cell communication GO:0010648 223 0.088
regulation of neuron apoptotic process GO:0043523 16 0.088
positive regulation of phosphorus metabolic process GO:0010562 139 0.086
Zebrafish Mouse
positive regulation of neuron differentiation GO:0045666 26 0.085
regulation of protein phosphorylation GO:0001932 64 0.084
Zebrafish Mouse
regulation of multi organism process GO:0043900 131 0.083
neuroblast fate determination GO:0007400 12 0.083
regulation of localization GO:0032879 275 0.082
negative regulation of signal transduction GO:0009968 206 0.081
regulation of anatomical structure size GO:0090066 163 0.078
death GO:0016265 284 0.078
positive regulation of protein modification process GO:0031401 58 0.077
Zebrafish Mouse
gastrulation with mouth forming first GO:0001703 36 0.075
positive regulation of organelle organization GO:0010638 65 0.073
Fly
stem cell fate determination GO:0048867 15 0.072
exocrine system development GO:0035272 162 0.071
Fly
regulation of molecular function GO:0065009 217 0.069
Zebrafish
gastrulation involving germ band extension GO:0010004 36 0.069
negative regulation of mitotic cell cycle GO:0045930 109 0.067
cell motility GO:0048870 251 0.066
positive regulation of cell division GO:0051781 16 0.066
Fly
regulation of developmental growth GO:0048638 174 0.065
negative regulation of cell cycle GO:0045786 116 0.064
taxis GO:0042330 304 0.064
asymmetric cell division GO:0008356 37 0.064
regulation of protein serine threonine kinase activity GO:0071900 25 0.063
Zebrafish
immune system development GO:0002520 57 0.063
Rat
regulation of behavior GO:0050795 75 0.062
ommatidial rotation GO:0016318 20 0.060
defense response GO:0006952 300 0.059
organonitrogen compound biosynthetic process GO:1901566 117 0.057
negative regulation of response to stimulus GO:0048585 258 0.056
negative regulation of cellular component organization GO:0051129 108 0.055
reproductive behavior GO:0019098 122 0.055
regulation of immune response GO:0050776 118 0.054
negative regulation of neuron differentiation GO:0045665 16 0.054
Mouse Rat
amide biosynthetic process GO:0043604 42 0.053
regulation of antimicrobial peptide production GO:0002784 44 0.053
antimicrobial humoral response GO:0019730 99 0.053
regulation of production of molecular mediator of immune response GO:0002700 44 0.053
programmed cell death GO:0012501 257 0.053
lateral inhibition GO:0046331 206 0.052
regulation of programmed cell death GO:0043067 152 0.052
regulation of immune effector process GO:0002697 52 0.051
multi organism behavior GO:0051705 175 0.051
epithelial cell development GO:0002064 274 0.051
hematopoietic or lymphoid organ development GO:0048534 57 0.050
Rat
developmental growth GO:0048589 280 0.047
imaginal disc derived appendage morphogenesis GO:0035114 395 0.047
somatic stem cell maintenance GO:0035019 14 0.046
regulation of cellular component size GO:0032535 98 0.046
regulation of cell death GO:0010941 173 0.046
central nervous system neuron development GO:0021954 8 0.045
eye photoreceptor cell fate commitment GO:0042706 37 0.045
locomotor rhythm GO:0045475 56 0.044
regulation of transferase activity GO:0051338 58 0.044
Zebrafish
positive regulation of neuron apoptotic process GO:0043525 1 0.043
regeneration GO:0031099 16 0.042
defense response to other organism GO:0098542 225 0.042
negative regulation of programmed cell death GO:0043069 72 0.042
bolwig s organ morphogenesis GO:0001746 8 0.041
oenocyte development GO:0007438 8 0.040
negative regulation of cell division GO:0051782 17 0.040
musculoskeletal movement GO:0050881 3 0.039
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.039
organic substance transport GO:0071702 257 0.037
regulation of extent of cell growth GO:0061387 8 0.037
regulation of antimicrobial humoral response GO:0002759 50 0.036
response to bacterium GO:0009617 198 0.035
regulation of humoral immune response GO:0002920 51 0.034
regulation of cell size GO:0008361 63 0.034
endoderm development GO:0007492 6 0.033
Zebrafish
camera type eye morphogenesis GO:0048593 2 0.033
ion transport GO:0006811 145 0.033
regulation of cell projection organization GO:0031344 92 0.032
regulation of response to biotic stimulus GO:0002831 63 0.032
compound eye photoreceptor fate commitment GO:0001752 36 0.032
response to oxygen containing compound GO:1901700 200 0.032
asymmetric neuroblast division GO:0055059 33 0.031
regulation of neuron death GO:1901214 26 0.031
neuroblast division GO:0055057 35 0.031
negative regulation of organelle organization GO:0010639 56 0.030
neuron apoptotic process GO:0051402 17 0.030
peptide biosynthetic process GO:0043043 42 0.030
cell type specific apoptotic process GO:0097285 38 0.029
pigmentation GO:0043473 75 0.028
digestive system development GO:0055123 149 0.028
regulation of anatomical structure morphogenesis GO:0022603 242 0.028
Mouse
multicellular organismal movement GO:0050879 3 0.028
reflex GO:0060004 6 0.028
endocytosis GO:0006897 310 0.027
oviposition GO:0018991 19 0.027
cellular modified amino acid metabolic process GO:0006575 45 0.027
regulation of cellular component movement GO:0051270 42 0.027
appendage development GO:0048736 401 0.026
regulation of growth GO:0040008 233 0.025
negative regulation of cell death GO:0060548 81 0.025
neural retina development GO:0003407 4 0.025
digestive tract development GO:0048565 149 0.025
production of molecular mediator of immune response GO:0002440 46 0.024
retina morphogenesis in camera type eye GO:0060042 2 0.024
apoptotic process GO:0006915 159 0.024
wound healing GO:0042060 75 0.024
regulation of locomotion GO:0040012 42 0.024
chemotaxis GO:0006935 249 0.024
antimicrobial peptide biosynthetic process GO:0002777 38 0.023
germ line stem cell maintenance GO:0030718 50 0.023
positive regulation of apoptotic process GO:0043065 47 0.023
larval development GO:0002164 104 0.022
epithelial cell migration open tracheal system GO:0007427 32 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
wing disc morphogenesis GO:0007472 344 0.021
response to ethanol GO:0045471 59 0.021
regulation of apoptotic process GO:0042981 130 0.020
intracellular transport GO:0046907 228 0.020
macromolecule catabolic process GO:0009057 161 0.020
actin filament based process GO:0030029 220 0.020
proteolysis GO:0006508 192 0.019
response to alcohol GO:0097305 95 0.019
retina development in camera type eye GO:0060041 4 0.019
neuron death GO:0070997 27 0.019
r8 cell fate commitment GO:0007460 6 0.019
ventral furrow formation GO:0007370 17 0.019
vesicle mediated transport GO:0016192 381 0.019
response to acid chemical GO:0001101 25 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
multi multicellular organism process GO:0044706 123 0.018
rhythmic behavior GO:0007622 76 0.018
establishment of tissue polarity GO:0007164 87 0.018
cell growth GO:0016049 108 0.018
neuron migration GO:0001764 5 0.017
negative regulation of stem cell proliferation GO:2000647 30 0.017
multicellular organismal reproductive behavior GO:0033057 110 0.017
muscle cell development GO:0055001 50 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
negative regulation of apoptotic process GO:0043066 63 0.017
salivary gland cell autophagic cell death GO:0035071 83 0.017
positive regulation of cell death GO:0010942 69 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
regulation of jak stat cascade GO:0046425 43 0.016
Mouse
establishment or maintenance of cell polarity GO:0007163 167 0.016
regulation of dendrite morphogenesis GO:0048814 28 0.016
developmental programmed cell death GO:0010623 138 0.016
homeostatic process GO:0042592 199 0.016

HLHmgamma disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
dysostosis DOID:1934 0 0.640
Human
musculoskeletal system disease DOID:17 0 0.640
Human
bone disease DOID:0080001 0 0.640
Human
disease of anatomical entity DOID:7 0 0.640
Human
connective tissue disease DOID:65 0 0.640
Human
bone development disease DOID:0080006 0 0.640
Human
spondylocostal dysostosis DOID:0050568 0 0.532
Human