Drosophila melanogaster

119 known processes

HLHmgamma (Dmel_CG8333)

E(spl) region transcript mgamma

(Aliases: CG8333,mB,Mgamma,E(spl)gamma,e(spl)mgamma,E(spl)-mgamma,E(Spl) HLH-m gamma,HLH-mgamma,Dmel\CG8333,E(spl) mgamma,Dm-mB,clone 1.49,HLHmB,bHLHb34,E(spl) m gamma,E(spl)mB,anon-EST:Liang-1.49,E(spl)mgamma,mgamma,E(spl)Mgamma)

HLHmgamma biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ precursor cell fate determination GO:0016360 19 1.000
Fly
cell fate determination involved in pattern specification GO:0060582 19 1.000
Fly
neuron fate determination GO:0048664 1 0.998
Mouse
formation of organ boundary GO:0010160 30 0.998
Fly
sensory organ boundary specification GO:0008052 22 0.996
Fly
glial cell fate commitment GO:0021781 3 0.991
Mouse
stem cell maintenance GO:0019827 67 0.986
Human Mouse Rat
regulation of neural precursor cell proliferation GO:2000177 35 0.977
cell fate commitment involved in pattern specification GO:0060581 31 0.975
Fly
notch signaling pathway GO:0007219 120 0.974
Human Zebrafish Mouse Fly
axon ensheathment in central nervous system GO:0032291 3 0.972
Mouse
r1 r6 cell differentiation GO:0048052 4 0.970
Fly
r7 cell differentiation GO:0045466 43 0.966
Fly
positive regulation of bmp signaling pathway GO:0030513 5 0.959
Mouse
formation of anatomical boundary GO:0048859 37 0.952
Fly
regulation of neuroblast proliferation GO:1902692 34 0.942
sex determination GO:0007530 18 0.932
Fly
nephron epithelium morphogenesis GO:0072088 3 0.932
Mouse
regulation of timing of cell differentiation GO:0048505 1 0.913
Mouse
tyrosine phosphorylation of stat protein GO:0007260 1 0.909
Mouse
negative regulation of gliogenesis GO:0014014 6 0.892
Mouse
regulation of glial cell differentiation GO:0045685 1 0.890
Mouse
cell fate specification GO:0001708 71 0.890
Worm
stem cell proliferation GO:0072089 88 0.889
organ formation GO:0048645 39 0.887
Fly
dosage compensation GO:0007549 16 0.882
Fly
neural precursor cell proliferation GO:0061351 75 0.870
regulation of gliogenesis GO:0014013 11 0.865
Mouse
malpighian tubule morphogenesis GO:0007443 44 0.863
cell maturation GO:0048469 144 0.860
Mouse
cell division GO:0051301 248 0.857
Fly
neuroblast proliferation GO:0007405 74 0.856
regulation of stem cell proliferation GO:0072091 40 0.855
renal system development GO:0072001 72 0.853
Mouse
sex determination establishment of x a ratio GO:0007540 1 0.841
Fly
regulation of mitosis GO:0007088 56 0.834
Fly
glial cell development GO:0021782 27 0.822
Mouse
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.822
renal tubule morphogenesis GO:0061333 44 0.822
Mouse
nuclear division GO:0000280 332 0.817
Fly
renal tubule development GO:0061326 64 0.810
Mouse
somatic sex determination GO:0018993 2 0.808
Fly
primary sex determination soma GO:0007539 2 0.807
Fly
neuronal stem cell maintenance GO:0097150 4 0.802
Human Mouse Rat
glial cell differentiation GO:0010001 35 0.802
Mouse Rat
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.799
regionalization GO:0003002 416 0.798
regulation of notch signaling pathway GO:0008593 100 0.795
Mouse
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.773
Mouse
single organism behavior GO:0044708 391 0.771
Fly
gliogenesis GO:0042063 80 0.764
Zebrafish Mouse Rat
negative regulation of stem cell differentiation GO:2000737 8 0.764
Human
mitotic nuclear division GO:0007067 213 0.755
Fly
cell fate determination GO:0001709 91 0.730
Mouse Fly
regulation of cell differentiation GO:0045595 302 0.710
chaeta morphogenesis GO:0008407 42 0.708
nephron tubule development GO:0072080 3 0.705
Mouse
organelle fission GO:0048285 340 0.699
Fly
regulation of mitotic cell cycle GO:0007346 190 0.694
Fly
respiratory system development GO:0060541 213 0.690
Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.689
nephron tubule formation GO:0072079 3 0.684
Mouse
nerve development GO:0021675 6 0.683
Mouse
axon development GO:0061564 297 0.680
Zebrafish
positive regulation of stem cell proliferation GO:2000648 8 0.679
embryonic epithelial tube formation GO:0001838 6 0.672
Mouse
positive regulation of nervous system development GO:0051962 69 0.670
positive regulation of mitotic cell cycle GO:0045931 34 0.664
Fly
positive regulation of neural precursor cell proliferation GO:2000179 8 0.662
negative regulation of cell development GO:0010721 62 0.656
Zebrafish Mouse Rat
hair cell differentiation GO:0035315 47 0.644
Mouse
tube formation GO:0035148 21 0.644
Mouse
neuroblast fate specification GO:0014018 2 0.639
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.639
Zebrafish
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.634
Mouse
stem cell differentiation GO:0048863 117 0.630
Human Mouse Rat
developmental maturation GO:0021700 172 0.627
Mouse
nephron epithelium development GO:0072009 3 0.611
Mouse
axon ensheathment GO:0008366 10 0.605
Mouse
embryonic hindgut morphogenesis GO:0048619 48 0.601
epithelial tube formation GO:0072175 7 0.588
Mouse
nephron tubule morphogenesis GO:0072078 3 0.580
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.578
negative regulation of nervous system development GO:0051961 92 0.571
Zebrafish Mouse Rat
regulation of cell cycle GO:0051726 291 0.567
Zebrafish Fly
nephron morphogenesis GO:0072028 3 0.559
Mouse
cranial nerve development GO:0021545 1 0.555
Mouse
regulation of nervous system development GO:0051960 248 0.550
urogenital system development GO:0001655 72 0.547
Mouse
positive regulation of gene expression GO:0010628 290 0.547
Mouse
regulation of cell cycle process GO:0010564 181 0.546
Fly
regulation of nuclear division GO:0051783 58 0.536
Fly
regulation of neurogenesis GO:0050767 158 0.529
organic acid metabolic process GO:0006082 103 0.529
tissue morphogenesis GO:0048729 297 0.528
Mouse
larval behavior GO:0030537 42 0.526
Fly
positive regulation of biosynthetic process GO:0009891 316 0.526
Mouse
positive regulation of developmental process GO:0051094 143 0.524
regulation of gene expression epigenetic GO:0040029 128 0.524
Fly
kidney epithelium development GO:0072073 3 0.518
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.513
regulation of cellular amino acid metabolic process GO:0006521 0 0.513
connective tissue development GO:0061448 3 0.511
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.509
Mouse
hindbrain development GO:0030902 2 0.508
Mouse
tube morphogenesis GO:0035239 191 0.504
Mouse Fly
stem cell fate commitment GO:0048865 25 0.499
central nervous system development GO:0007417 201 0.498
Zebrafish Mouse Rat Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.484
forebrain development GO:0030900 2 0.483
Mouse Rat
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.482
negative regulation of transcription dna templated GO:0045892 237 0.482
regulation of response to stress GO:0080134 200 0.474
Fly
intracellular signal transduction GO:0035556 300 0.473
Mouse
stem cell fate specification GO:0048866 2 0.472
compound eye photoreceptor cell differentiation GO:0001751 140 0.470
Fly
negative regulation of neurogenesis GO:0050768 53 0.470
Zebrafish Mouse Rat
regulation of multicellular organismal development GO:2000026 414 0.467
axonogenesis GO:0007409 290 0.464
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 405 0.461
Zebrafish Mouse
regulation of bmp signaling pathway GO:0030510 23 0.453
Mouse
stem cell development GO:0048864 79 0.452
Human Mouse Rat
immune system process GO:0002376 347 0.449
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.448
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.445
Mouse
anterior posterior pattern specification GO:0009952 136 0.441
Zebrafish Mouse Worm
head development GO:0060322 135 0.441
Zebrafish Mouse Rat Fly
nephron development GO:0072006 3 0.441
Mouse
telencephalon development GO:0021537 2 0.440
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.439
response to abiotic stimulus GO:0009628 341 0.438
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.438
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.436
Mouse
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.434
Rat
kidney development GO:0001822 3 0.433
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.432
epidermal cell differentiation GO:0009913 51 0.430
Mouse Worm
regulation of cellular ketone metabolic process GO:0010565 3 0.425
positive regulation of nucleic acid templated transcription GO:1903508 266 0.418
Mouse
adult behavior GO:0030534 137 0.413
Fly
positive regulation of response to stimulus GO:0048584 323 0.408
Mouse
bmp signaling pathway GO:0030509 27 0.406
Mouse
regulation of organelle organization GO:0033043 196 0.404
Fly
organonitrogen compound metabolic process GO:1901564 318 0.401
positive regulation of rna biosynthetic process GO:1902680 266 0.399
Mouse
dorsal ventral pattern formation GO:0009953 133 0.395
peptidyl tyrosine phosphorylation GO:0018108 24 0.391
Mouse
regulation of cellular response to stress GO:0080135 89 0.391
Fly
locomotory behavior GO:0007626 176 0.389
Fly
hindgut morphogenesis GO:0007442 58 0.389
dendrite morphogenesis GO:0048813 199 0.385
Fly
gland development GO:0048732 191 0.383
Fly
negative regulation of notch signaling pathway GO:0045746 41 0.377
regulation of stem cell differentiation GO:2000736 14 0.370
Human
startle response GO:0001964 16 0.370
Fly
positive regulation of signaling GO:0023056 243 0.362
Mouse
positive regulation of neuroblast proliferation GO:0002052 7 0.361
eye photoreceptor cell differentiation GO:0001754 145 0.360
Fly
mesoderm development GO:0007498 78 0.359
Fly
cell proliferation GO:0008283 299 0.358
regulation of neuron differentiation GO:0045664 103 0.357
Mouse Rat
negative regulation of rna biosynthetic process GO:1902679 240 0.353
regulation of cell development GO:0060284 215 0.350
positive regulation of neurogenesis GO:0050769 41 0.350
regulation of cellular amine metabolic process GO:0033238 3 0.350
kidney morphogenesis GO:0060993 3 0.348
Mouse
sensory organ morphogenesis GO:0090596 260 0.348
Fly
ensheathment of neurons GO:0007272 10 0.347
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.343
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.342
Zebrafish
photoreceptor cell differentiation GO:0046530 170 0.341
Fly
dendrite development GO:0016358 204 0.335
Fly
cellular ketone metabolic process GO:0042180 24 0.333
rhythmic process GO:0048511 106 0.330
Mouse
oxoacid metabolic process GO:0043436 103 0.327
positive regulation of cell communication GO:0010647 250 0.326
Mouse
segmentation GO:0035282 207 0.324
Zebrafish Mouse
developmental cell growth GO:0048588 52 0.320
segment specification GO:0007379 33 0.319
Zebrafish Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.316
carboxylic acid metabolic process GO:0019752 92 0.310
peptide metabolic process GO:0006518 80 0.308
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.308
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.307
regulation of cell division GO:0051302 72 0.306
Fly
positive regulation of rna metabolic process GO:0051254 271 0.304
Mouse
regulation of response to dna damage stimulus GO:2001020 23 0.302
Fly
positive regulation of signal transduction GO:0009967 223 0.302
Mouse
compound eye morphogenesis GO:0001745 249 0.301
Fly
camera type eye development GO:0043010 4 0.300
Mouse
regulation of immune system process GO:0002682 176 0.299
Rat
negative regulation of glial cell proliferation GO:0060253 6 0.296
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.294
Mouse
cellular amine metabolic process GO:0044106 12 0.289
positive regulation of protein metabolic process GO:0051247 128 0.286
Zebrafish Mouse
peripheral nervous system neuron development GO:0048935 8 0.286
Zebrafish
proximal distal pattern formation GO:0009954 15 0.285
Mouse
morphogenesis of an epithelium GO:0002009 276 0.284
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.284
brain development GO:0007420 120 0.282
Zebrafish Mouse Rat Fly
small molecule metabolic process GO:0044281 305 0.281
neuron fate commitment GO:0048663 50 0.280
Mouse
eye morphogenesis GO:0048592 260 0.278
Fly
axon extension involved in axon guidance GO:0048846 10 0.277
salivary gland development GO:0007431 162 0.275
Fly
transmission of nerve impulse GO:0019226 12 0.274
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.273
Mouse
peptidyl tyrosine modification GO:0018212 24 0.267
Mouse
neuroepithelial cell differentiation GO:0060563 6 0.266
epidermis development GO:0008544 65 0.262
Mouse Worm
regulation of intracellular signal transduction GO:1902531 236 0.261
Mouse
regulation of neuron projection development GO:0010975 69 0.260
adult locomotory behavior GO:0008344 76 0.260
Fly
regulation of cell morphogenesis GO:0022604 163 0.258
positive regulation of notch signaling pathway GO:0045747 34 0.246
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.245
cellular amide metabolic process GO:0043603 80 0.244
regulation of membrane potential GO:0042391 35 0.240
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.240
Mouse
negative regulation of developmental process GO:0051093 201 0.239
Human Zebrafish Mouse Rat
open tracheal system development GO:0007424 204 0.238
Fly
imaginal disc pattern formation GO:0007447 91 0.238
positive regulation of cellular protein metabolic process GO:0032270 118 0.238
Zebrafish Mouse
positive regulation of cell cycle GO:0045787 43 0.236
Zebrafish Fly
negative regulation of biosynthetic process GO:0009890 277 0.235
negative regulation of multicellular organismal process GO:0051241 142 0.234
Zebrafish Mouse Rat
regulation of glial cell proliferation GO:0060251 11 0.233
positive regulation of cellular component organization GO:0051130 156 0.231
Fly
gland morphogenesis GO:0022612 145 0.231
Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.229
positive regulation of phosphate metabolic process GO:0045937 139 0.228
Zebrafish Mouse
tube development GO:0035295 244 0.227
Zebrafish Mouse Fly
humoral immune response GO:0006959 117 0.226
wing disc pattern formation GO:0035222 66 0.226
morphogenesis of embryonic epithelium GO:0016331 94 0.225
Mouse
peripheral nervous system development GO:0007422 52 0.223
Zebrafish
malpighian tubule development GO:0072002 64 0.216
positive regulation of cell proliferation GO:0008284 47 0.214
neuron fate specification GO:0048665 12 0.213
negative regulation of gene expression GO:0010629 387 0.213
regulation of axon extension GO:0030516 8 0.212
embryonic morphogenesis GO:0048598 206 0.212
Zebrafish Mouse
eye development GO:0001654 323 0.210
Zebrafish Mouse Fly
cellular amino acid metabolic process GO:0006520 61 0.205
positive regulation of cell differentiation GO:0045597 64 0.204
regulation of phosphorylation GO:0042325 147 0.201
Zebrafish Mouse
macromolecular complex assembly GO:0065003 256 0.198
Mouse
smoothened signaling pathway GO:0007224 49 0.196
Mouse
regulation of axon extension involved in axon guidance GO:0048841 4 0.194
negative regulation of cell differentiation GO:0045596 143 0.194
Human Zebrafish Mouse Rat
regulation of epithelial cell differentiation GO:0030856 4 0.193
compound eye development GO:0048749 307 0.191
Fly
neuron projection guidance GO:0097485 241 0.191
protein modification process GO:0036211 438 0.191
Zebrafish Mouse
cellular protein modification process GO:0006464 438 0.187
Zebrafish Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.187
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.187
peptidyl amino acid modification GO:0018193 105 0.184
Mouse
positive regulation of cell development GO:0010720 61 0.182
hindgut development GO:0061525 58 0.182
protein complex biogenesis GO:0070271 201 0.182
Mouse
jak stat cascade GO:0007259 49 0.181
Mouse
regulation of protein modification process GO:0031399 112 0.181
Zebrafish Mouse
larval locomotory behavior GO:0008345 27 0.180
Fly
spinal cord patterning GO:0021511 1 0.179
response to other organism GO:0051707 293 0.178
neuron projection extension GO:1990138 32 0.178
epithelial cell differentiation GO:0030855 322 0.178
Mouse Worm
regulation of protein metabolic process GO:0051246 256 0.176
Zebrafish Mouse
response to hypoxia GO:0001666 53 0.174
Fly
neuromuscular process GO:0050905 21 0.174
Fly
immune response GO:0006955 246 0.173
glial cell proliferation GO:0014009 13 0.172
spinal cord development GO:0021510 1 0.171
cellular response to dna damage stimulus GO:0006974 223 0.164
Fly
skin development GO:0043588 65 0.164
Mouse Worm
positive regulation of cell cycle process GO:0090068 28 0.163
Fly
biological adhesion GO:0022610 138 0.162
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.159
neuroblast fate commitment GO:0014017 19 0.155
neuronal action potential GO:0019228 10 0.152
Mouse
positive regulation of protein kinase activity GO:0045860 25 0.151
Zebrafish
hematopoietic progenitor cell differentiation GO:0002244 1 0.151
Rat
protein complex assembly GO:0006461 200 0.151
Mouse
regulation of oviposition GO:0046662 14 0.149
bolwig s organ development GO:0055034 8 0.146
neurological system process GO:0050877 358 0.145
Mouse Fly
regulation of protein kinase activity GO:0045859 51 0.143
Zebrafish
positive regulation of molecular function GO:0044093 136 0.143
Zebrafish
positive regulation of intracellular signal transduction GO:1902533 116 0.142
Mouse
central nervous system neuron differentiation GO:0021953 8 0.142
Rat
multi organism reproductive behavior GO:0044705 121 0.142
malpighian tubule tip cell differentiation GO:0061382 9 0.140
response to external biotic stimulus GO:0043207 293 0.140
positive regulation of transferase activity GO:0051347 26 0.140
Zebrafish
neuroblast differentiation GO:0014016 29 0.139
digestive tract morphogenesis GO:0048546 127 0.137
response to decreased oxygen levels GO:0036293 58 0.137
Fly
regulation of axonogenesis GO:0050770 32 0.137
phosphorylation GO:0016310 294 0.136
Zebrafish Mouse
brain morphogenesis GO:0048854 16 0.133
Fly
amine metabolic process GO:0009308 12 0.129
action potential GO:0001508 13 0.127
Mouse
protein phosphorylation GO:0006468 169 0.127
Zebrafish Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.125
response to biotic stimulus GO:0009607 294 0.125
regulation of axon guidance GO:1902667 10 0.125
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.124
regulation of cell proliferation GO:0042127 163 0.122
chaeta development GO:0022416 97 0.122
positive regulation of phosphorylation GO:0042327 87 0.119
Zebrafish Mouse
spinal cord dorsal ventral patterning GO:0021513 1 0.118
wing disc dorsal ventral pattern formation GO:0048190 47 0.118
cell migration GO:0016477 238 0.118
salivary gland morphogenesis GO:0007435 145 0.118
Fly
enzyme linked receptor protein signaling pathway GO:0007167 179 0.116
Mouse
epithelial cell proliferation GO:0050673 15 0.115
hemopoiesis GO:0030097 46 0.115
Rat
response to organic substance GO:0010033 284 0.113
regulation of kinase activity GO:0043549 53 0.112
Zebrafish
regulation of phosphate metabolic process GO:0019220 210 0.112
Zebrafish Mouse
positive regulation of protein phosphorylation GO:0001934 34 0.110
Zebrafish Mouse
negative regulation of immune system process GO:0002683 50 0.110
Rat
regulation of cellular amide metabolic process GO:0034248 39 0.110
negative regulation of cell cycle process GO:0010948 109 0.109
positive regulation of programmed cell death GO:0043068 62 0.109
body morphogenesis GO:0010171 2 0.107
glandular epithelial cell differentiation GO:0002067 1 0.107
response to oxygen levels GO:0070482 59 0.106
Fly
epithelial tube morphogenesis GO:0060562 88 0.104
Mouse
positive regulation of kinase activity GO:0033674 25 0.104
Zebrafish
cell death GO:0008219 279 0.102
localization of cell GO:0051674 257 0.102
negative regulation of signaling GO:0023057 219 0.100
regulation of catalytic activity GO:0050790 185 0.100
Zebrafish
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.100
axon extension GO:0048675 32 0.099
positive regulation of catalytic activity GO:0043085 118 0.099
Zebrafish
regulation of reproductive process GO:2000241 54 0.098
cell adhesion GO:0007155 136 0.097
Mouse
medulla oblongata development GO:0021550 2 0.096
multicellular organismal signaling GO:0035637 12 0.094
Mouse
regulation of cellular protein metabolic process GO:0032268 243 0.092
Zebrafish Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.091
Zebrafish Mouse
antimicrobial peptide production GO:0002775 46 0.091
axon guidance GO:0007411 233 0.089
regulation of response to external stimulus GO:0032101 115 0.089
peripheral nervous system neuron differentiation GO:0048934 8 0.088
Zebrafish
negative regulation of cell communication GO:0010648 223 0.088
regulation of neuron apoptotic process GO:0043523 16 0.088
positive regulation of phosphorus metabolic process GO:0010562 139 0.086
Zebrafish Mouse
positive regulation of neuron differentiation GO:0045666 26 0.085
regulation of protein phosphorylation GO:0001932 64 0.084
Zebrafish Mouse
regulation of multi organism process GO:0043900 131 0.083
neuroblast fate determination GO:0007400 12 0.083
regulation of localization GO:0032879 275 0.082
negative regulation of signal transduction GO:0009968 206 0.081
regulation of anatomical structure size GO:0090066 163 0.078
death GO:0016265 284 0.078
positive regulation of protein modification process GO:0031401 58 0.077
Zebrafish Mouse
gastrulation with mouth forming first GO:0001703 36 0.075
positive regulation of organelle organization GO:0010638 65 0.073
Fly
stem cell fate determination GO:0048867 15 0.072
exocrine system development GO:0035272 162 0.071
Fly
regulation of molecular function GO:0065009 217 0.069
Zebrafish
gastrulation involving germ band extension GO:0010004 36 0.069
negative regulation of mitotic cell cycle GO:0045930 109 0.067
cell motility GO:0048870 251 0.066
positive regulation of cell division GO:0051781 16 0.066
Fly
regulation of developmental growth GO:0048638 174 0.065
negative regulation of cell cycle GO:0045786 116 0.064
taxis GO:0042330 304 0.064
asymmetric cell division GO:0008356 37 0.064
regulation of protein serine threonine kinase activity GO:0071900 25 0.063
Zebrafish
immune system development GO:0002520 57 0.063
Rat
regulation of behavior GO:0050795 75 0.062
ommatidial rotation GO:0016318 20 0.060
defense response GO:0006952 300 0.059
organonitrogen compound biosynthetic process GO:1901566 117 0.057
negative regulation of response to stimulus GO:0048585 258 0.056
negative regulation of cellular component organization GO:0051129 108 0.055
reproductive behavior GO:0019098 122 0.055
regulation of immune response GO:0050776 118 0.054
negative regulation of neuron differentiation GO:0045665 16 0.054
Mouse Rat
amide biosynthetic process GO:0043604 42 0.053
regulation of antimicrobial peptide production GO:0002784 44 0.053
antimicrobial humoral response GO:0019730 99 0.053
regulation of production of molecular mediator of immune response GO:0002700 44 0.053
programmed cell death GO:0012501 257 0.053
lateral inhibition GO:0046331 206 0.052
regulation of programmed cell death GO:0043067 152 0.052
regulation of immune effector process GO:0002697 52 0.051
multi organism behavior GO:0051705 175 0.051
epithelial cell development GO:0002064 274 0.051
hematopoietic or lymphoid organ development GO:0048534 57 0.050
Rat
developmental growth GO:0048589 280 0.047
imaginal disc derived appendage morphogenesis GO:0035114 395 0.047
somatic stem cell maintenance GO:0035019 14 0.046
regulation of cellular component size GO:0032535 98 0.046
regulation of cell death GO:0010941 173 0.046
central nervous system neuron development GO:0021954 8 0.045
eye photoreceptor cell fate commitment GO:0042706 37 0.045
locomotor rhythm GO:0045475 56 0.044
regulation of transferase activity GO:0051338 58 0.044
Zebrafish
positive regulation of neuron apoptotic process GO:0043525 1 0.043
regeneration GO:0031099 16 0.042
defense response to other organism GO:0098542 225 0.042
negative regulation of programmed cell death GO:0043069 72 0.042
bolwig s organ morphogenesis GO:0001746 8 0.041
oenocyte development GO:0007438 8 0.040
negative regulation of cell division GO:0051782 17 0.040
musculoskeletal movement GO:0050881 3 0.039
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.039
organic substance transport GO:0071702 257 0.037
regulation of extent of cell growth GO:0061387 8 0.037
regulation of antimicrobial humoral response GO:0002759 50 0.036
response to bacterium GO:0009617 198 0.035
regulation of humoral immune response GO:0002920 51 0.034
regulation of cell size GO:0008361 63 0.034
endoderm development GO:0007492 6 0.033
Zebrafish
camera type eye morphogenesis GO:0048593 2 0.033
ion transport GO:0006811 145 0.033
regulation of cell projection organization GO:0031344 92 0.032
regulation of response to biotic stimulus GO:0002831 63 0.032
compound eye photoreceptor fate commitment GO:0001752 36 0.032
response to oxygen containing compound GO:1901700 200 0.032
asymmetric neuroblast division GO:0055059 33 0.031
regulation of neuron death GO:1901214 26 0.031
neuroblast division GO:0055057 35 0.031
negative regulation of organelle organization GO:0010639 56 0.030
neuron apoptotic process GO:0051402 17 0.030
peptide biosynthetic process GO:0043043 42 0.030
cell type specific apoptotic process GO:0097285 38 0.029
pigmentation GO:0043473 75 0.028
digestive system development GO:0055123 149 0.028
regulation of anatomical structure morphogenesis GO:0022603 242 0.028
Mouse
multicellular organismal movement GO:0050879 3 0.028
reflex GO:0060004 6 0.028
endocytosis GO:0006897 310 0.027
oviposition GO:0018991 19 0.027
cellular modified amino acid metabolic process GO:0006575 45 0.027
regulation of cellular component movement GO:0051270 42 0.027
appendage development GO:0048736 401 0.026
regulation of growth GO:0040008 233 0.025
negative regulation of cell death GO:0060548 81 0.025
neural retina development GO:0003407 4 0.025
digestive tract development GO:0048565 149 0.025
production of molecular mediator of immune response GO:0002440 46 0.024
retina morphogenesis in camera type eye GO:0060042 2 0.024
apoptotic process GO:0006915 159 0.024
wound healing GO:0042060 75 0.024
regulation of locomotion GO:0040012 42 0.024
chemotaxis GO:0006935 249 0.024
antimicrobial peptide biosynthetic process GO:0002777 38 0.023
germ line stem cell maintenance GO:0030718 50 0.023
positive regulation of apoptotic process GO:0043065 47 0.023
larval development GO:0002164 104 0.022
epithelial cell migration open tracheal system GO:0007427 32 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
wing disc morphogenesis GO:0007472 344 0.021
response to ethanol GO:0045471 59 0.021
regulation of apoptotic process GO:0042981 130 0.020
intracellular transport GO:0046907 228 0.020
macromolecule catabolic process GO:0009057 161 0.020
actin filament based process GO:0030029 220 0.020
proteolysis GO:0006508 192 0.019
response to alcohol GO:0097305 95 0.019
retina development in camera type eye GO:0060041 4 0.019
neuron death GO:0070997 27 0.019
r8 cell fate commitment GO:0007460 6 0.019
ventral furrow formation GO:0007370 17 0.019
vesicle mediated transport GO:0016192 381 0.019
response to acid chemical GO:0001101 25 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
multi multicellular organism process GO:0044706 123 0.018
rhythmic behavior GO:0007622 76 0.018
establishment of tissue polarity GO:0007164 87 0.018
cell growth GO:0016049 108 0.018
neuron migration GO:0001764 5 0.017
negative regulation of stem cell proliferation GO:2000647 30 0.017
multicellular organismal reproductive behavior GO:0033057 110 0.017
muscle cell development GO:0055001 50 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
negative regulation of apoptotic process GO:0043066 63 0.017
salivary gland cell autophagic cell death GO:0035071 83 0.017
positive regulation of cell death GO:0010942 69 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
regulation of jak stat cascade GO:0046425 43 0.016
Mouse
establishment or maintenance of cell polarity GO:0007163 167 0.016
regulation of dendrite morphogenesis GO:0048814 28 0.016
developmental programmed cell death GO:0010623 138 0.016
homeostatic process GO:0042592 199 0.016

HLHmgamma disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.640
Human
bone disease DOID:0080001 0 0.640
Human
disease of anatomical entity DOID:7 0 0.640
Human
dysostosis DOID:1934 0 0.640
Human
musculoskeletal system disease DOID:17 0 0.640
Human
connective tissue disease DOID:65 0 0.640
Human
spondylocostal dysostosis DOID:0050568 0 0.532
Human