Drosophila melanogaster

7 known processes

Prosalpha1 (Dmel_CG18495)

Proteasome alpha1 subunit

(Aliases: Prosalpha6,18495,prosalpha1,CG18495,PSA6_DROME,Dmel\CG18495)

Prosalpha1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye photoreceptor cell development GO:0042462 81 0.353
compound eye development GO:0048749 307 0.335
compound eye morphogenesis GO:0001745 249 0.266
organelle fission GO:0048285 340 0.254
compound eye photoreceptor development GO:0042051 78 0.238
rhabdomere development GO:0042052 38 0.224
eye photoreceptor cell differentiation GO:0001754 145 0.213
compound eye photoreceptor cell differentiation GO:0001751 140 0.166
positive regulation of nucleic acid templated transcription GO:1903508 266 0.153
macromolecular complex assembly GO:0065003 256 0.145
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.135
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.127
photoreceptor cell differentiation GO:0046530 170 0.118
nuclear division GO:0000280 332 0.117
regulation of catabolic process GO:0009894 170 0.105
protein complex biogenesis GO:0070271 201 0.101
sensory organ morphogenesis GO:0090596 260 0.100
eye development GO:0001654 323 0.098
post embryonic appendage morphogenesis GO:0035120 385 0.077
protein complex assembly GO:0006461 200 0.076
wing disc morphogenesis GO:0007472 344 0.074
imaginal disc derived appendage morphogenesis GO:0035114 395 0.072
appendage morphogenesis GO:0035107 397 0.069
positive regulation of macromolecule metabolic process GO:0010604 405 0.069
eye morphogenesis GO:0048592 260 0.067
photoreceptor cell development GO:0042461 96 0.064
cellular macromolecular complex assembly GO:0034622 153 0.050
imaginal disc derived appendage development GO:0048737 399 0.049
synaptic transmission GO:0007268 288 0.049
establishment of localization in cell GO:0051649 402 0.048
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.047
Yeast
cellular macromolecule catabolic process GO:0044265 136 0.045
Human Yeast
spindle organization GO:0007051 253 0.045
rhodopsin metabolic process GO:0046154 10 0.044
meiotic cell cycle GO:0051321 171 0.043
cellular protein catabolic process GO:0044257 83 0.042
Human Yeast
basolateral protein localization GO:0061467 1 0.041
cilium morphogenesis GO:0060271 39 0.039
photoreceptor cell maintenance GO:0045494 11 0.039
positive regulation of biosynthetic process GO:0009891 316 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.038
digestive tract morphogenesis GO:0048546 127 0.037
positive regulation of protein metabolic process GO:0051247 128 0.036
homeostatic process GO:0042592 199 0.036
single organism behavior GO:0044708 391 0.035
proteasomal protein catabolic process GO:0010498 59 0.035
Yeast
death GO:0016265 284 0.034
male meiosis GO:0007140 52 0.034
cell death GO:0008219 279 0.034
meiotic nuclear division GO:0007126 151 0.033
positive regulation of phosphorylation GO:0042327 87 0.033
microtubule organizing center organization GO:0031023 168 0.033
appendage development GO:0048736 401 0.033
anatomical structure homeostasis GO:0060249 97 0.032
centrosome organization GO:0051297 163 0.032
regulation of catalytic activity GO:0050790 185 0.032
positive regulation of cellular component organization GO:0051130 156 0.031
body morphogenesis GO:0010171 2 0.031
single organism biosynthetic process GO:0044711 206 0.029
mitotic nuclear division GO:0007067 213 0.029
proteolysis GO:0006508 192 0.029
Human Yeast
catabolic process GO:0009056 409 0.029
Human Yeast
positive regulation of molecular function GO:0044093 136 0.028
Human
positive regulation of cellular protein metabolic process GO:0032270 118 0.028
modification dependent macromolecule catabolic process GO:0043632 79 0.028
Yeast
positive regulation of rna biosynthetic process GO:1902680 266 0.027
regulation of cell morphogenesis GO:0022604 163 0.027
synaptic vesicle transport GO:0048489 50 0.027
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.027
positive regulation of cell communication GO:0010647 250 0.026
cellular protein modification process GO:0006464 438 0.025
organic substance catabolic process GO:1901575 308 0.024
Human Yeast
small molecule metabolic process GO:0044281 305 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.023
hydrogen peroxide metabolic process GO:0042743 6 0.023
positive regulation of signaling GO:0023056 243 0.023
cellular catabolic process GO:0044248 372 0.023
Human Yeast
regulation of cell development GO:0060284 215 0.023
digestive system development GO:0055123 149 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.023
Human Yeast
protein heterooligomerization GO:0051291 4 0.023
macromolecule catabolic process GO:0009057 161 0.022
Human Yeast
regionalization GO:0003002 416 0.022
positive regulation of gene expression GO:0010628 290 0.022
positive regulation of cellular catabolic process GO:0031331 95 0.020
regulation of anatomical structure morphogenesis GO:0022603 242 0.020
protein catabolic process GO:0030163 101 0.020
Human Yeast
positive regulation of catalytic activity GO:0043085 118 0.020
multicellular organismal homeostasis GO:0048871 41 0.020
positive regulation of transcription dna templated GO:0045893 266 0.020
single organism catabolic process GO:0044712 228 0.019
tissue homeostasis GO:0001894 36 0.019
regulation of hydrolase activity GO:0051336 97 0.019
protein modification process GO:0036211 438 0.018
organic acid metabolic process GO:0006082 103 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
regulation of phosphorylation GO:0042325 147 0.017
regulation of proteolysis GO:0030162 87 0.017
negative regulation of gene expression GO:0010629 387 0.017
establishment of synaptic vesicle localization GO:0097480 50 0.017
regulation of phosphate metabolic process GO:0019220 210 0.017
positive regulation of catabolic process GO:0009896 105 0.017
posttranscriptional regulation of gene expression GO:0010608 145 0.017
tube development GO:0035295 244 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.017
protein hydroxylation GO:0018126 1 0.017
embryonic development via the syncytial blastoderm GO:0001700 148 0.016
programmed cell death GO:0012501 257 0.016
mitotic spindle elongation GO:0000022 81 0.016
single organism intracellular transport GO:1902582 207 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
synaptic vesicle localization GO:0097479 53 0.016
retina homeostasis GO:0001895 13 0.016
regulation of organelle organization GO:0033043 196 0.015
regulation of nervous system development GO:0051960 248 0.015
synaptic vesicle endocytosis GO:0048488 28 0.015
androgen metabolic process GO:0008209 1 0.015
intracellular signal transduction GO:0035556 300 0.015
regulation of neuron differentiation GO:0045664 103 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
protein localization GO:0008104 284 0.014
regulation of protein metabolic process GO:0051246 256 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
asymmetric protein localization GO:0008105 33 0.014
endomembrane system organization GO:0010256 119 0.014
rho protein signal transduction GO:0007266 14 0.014
regulation of rna splicing GO:0043484 69 0.014
tube morphogenesis GO:0035239 191 0.014
regulation of mrna processing GO:0050684 71 0.013
membrane organization GO:0061024 112 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
response to bacterium GO:0009617 198 0.013
regulation of rho protein signal transduction GO:0035023 20 0.013
regulation of anatomical structure size GO:0090066 163 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
positive regulation of signal transduction GO:0009967 223 0.012
maintenance of cell polarity GO:0030011 18 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
defense response to other organism GO:0098542 225 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
cell proliferation GO:0008283 299 0.012
mrna processing GO:0006397 104 0.012
kidney development GO:0001822 3 0.012
regulation of proteasomal protein catabolic process GO:0061136 39 0.012
cell division GO:0051301 248 0.012
regulation of localization GO:0032879 275 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
regulation of molecular function GO:0065009 217 0.012
Human
protein phosphorylation GO:0006468 169 0.012
eye pigment metabolic process GO:0042441 33 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.012
epithelial cell differentiation GO:0030855 322 0.011
response to other organism GO:0051707 293 0.011
spindle elongation GO:0051231 83 0.011
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.011
establishment of organelle localization GO:0051656 122 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
vesicle localization GO:0051648 55 0.011
dna metabolic process GO:0006259 227 0.011
aging GO:0007568 143 0.011
growth GO:0040007 359 0.011
larval development GO:0002164 104 0.011
chromosome organization GO:0051276 360 0.011
apoptotic process GO:0006915 159 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
immune response GO:0006955 246 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
single organism membrane organization GO:0044802 93 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
Yeast
negative regulation of rna metabolic process GO:0051253 251 0.010

Prosalpha1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011