Drosophila melanogaster

34 known processes

smi35A (Dmel_CG4551)

smell impaired 35A

(Aliases: DYRK,Dmel\CG4551,Dyrk2,DYRK2,BG:DS01523.3,dDYRK2,CG4551)

smi35A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.779
chemosensory behavior GO:0007635 106 0.739
imaginal disc derived wing morphogenesis GO:0007476 337 0.735
growth GO:0040007 359 0.726
wing disc morphogenesis GO:0007472 344 0.665
imaginal disc derived appendage morphogenesis GO:0035114 395 0.653
imaginal disc derived appendage development GO:0048737 399 0.631
taxis GO:0042330 304 0.604
post embryonic appendage morphogenesis GO:0035120 385 0.585
appendage development GO:0048736 401 0.517
olfactory behavior GO:0042048 97 0.472
developmental programmed cell death GO:0010623 138 0.460
appendage morphogenesis GO:0035107 397 0.407
neuron projection guidance GO:0097485 241 0.396
developmental growth GO:0048589 280 0.365
chemotaxis GO:0006935 249 0.230
axon guidance GO:0007411 233 0.229
negative regulation of growth GO:0045926 84 0.202
positive regulation of signal transduction GO:0009967 223 0.184
striated muscle cell differentiation GO:0051146 90 0.157
positive regulation of cell communication GO:0010647 250 0.153
positive regulation of apoptotic signaling pathway GO:2001235 4 0.150
positive regulation of response to stimulus GO:0048584 323 0.146
axon development GO:0061564 297 0.117
single organism biosynthetic process GO:0044711 206 0.113
epithelial cell differentiation GO:0030855 322 0.110
vesicle mediated transport GO:0016192 381 0.103
positive regulation of signaling GO:0023056 243 0.100
head development GO:0060322 135 0.098
negative regulation of developmental growth GO:0048640 64 0.094
brain development GO:0007420 120 0.092
establishment or maintenance of cell polarity GO:0007163 167 0.092
synaptic growth at neuromuscular junction GO:0051124 119 0.090
glial cell development GO:0021782 27 0.088
multi organism behavior GO:0051705 175 0.087
intracellular signal transduction GO:0035556 300 0.086
endocytosis GO:0006897 310 0.085
regulation of nervous system development GO:0051960 248 0.084
carbohydrate derivative biosynthetic process GO:1901137 85 0.082
positive regulation of cell death GO:0010942 69 0.076
purine nucleotide biosynthetic process GO:0006164 29 0.075
organonitrogen compound metabolic process GO:1901564 318 0.073
organonitrogen compound biosynthetic process GO:1901566 117 0.072
cell recognition GO:0008037 102 0.070
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.068
establishment of glial blood brain barrier GO:0060857 14 0.063
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.063
death GO:0016265 284 0.061
morphogenesis of an epithelium GO:0002009 276 0.060
cell migration GO:0016477 238 0.059
dopamine receptor signaling pathway GO:0007212 4 0.059
negative regulation of nervous system development GO:0051961 92 0.058
chromosome segregation GO:0007059 157 0.057
cell death GO:0008219 279 0.056
regulation of anatomical structure size GO:0090066 163 0.055
response to light stimulus GO:0009416 124 0.055
protein import into nucleus GO:0006606 51 0.055
phosphorylation GO:0016310 294 0.054
regulation of intracellular signal transduction GO:1902531 236 0.052
negative regulation of developmental process GO:0051093 201 0.050
negative regulation of rna metabolic process GO:0051253 251 0.049
regulation of cyclase activity GO:0031279 13 0.048
phagocytosis GO:0006909 215 0.048
organic acid metabolic process GO:0006082 103 0.047
cyclic nucleotide metabolic process GO:0009187 28 0.047
protein localization GO:0008104 284 0.047
ovarian follicle cell development GO:0030707 248 0.046
cellular response to chemical stimulus GO:0070887 199 0.045
response to other organism GO:0051707 293 0.043
carboxylic acid metabolic process GO:0019752 92 0.042
response to external biotic stimulus GO:0043207 293 0.041
single organism catabolic process GO:0044712 228 0.041
nucleotide biosynthetic process GO:0009165 34 0.040
multicellular organismal aging GO:0010259 140 0.040
tube morphogenesis GO:0035239 191 0.040
lipid storage GO:0019915 38 0.039
cytoskeleton dependent cytokinesis GO:0061640 81 0.038
negative regulation of cellular component organization GO:0051129 108 0.037
immune system process GO:0002376 347 0.037
organic substance transport GO:0071702 257 0.037
regulation of organ morphogenesis GO:2000027 78 0.036
negative regulation of cell differentiation GO:0045596 143 0.035
regulation of localization GO:0032879 275 0.035
jak stat cascade GO:0007259 49 0.035
nucleoside phosphate metabolic process GO:0006753 162 0.035
nucleotide metabolic process GO:0009117 161 0.035
neuron recognition GO:0008038 101 0.035
response to biotic stimulus GO:0009607 294 0.034
organelle localization GO:0051640 148 0.034
regulation of protein import into nucleus GO:0042306 28 0.034
amine metabolic process GO:0009308 12 0.033
meiotic cell cycle GO:0051321 171 0.033
forebrain development GO:0030900 2 0.032
establishment of localization in cell GO:0051649 402 0.032
cellular macromolecule localization GO:0070727 220 0.032
axonogenesis GO:0007409 290 0.031
regulation of cellular component biogenesis GO:0044087 201 0.031
ras protein signal transduction GO:0007265 88 0.031
cation transport GO:0006812 110 0.030
cell proliferation GO:0008283 299 0.030
positive regulation of programmed cell death GO:0043068 62 0.030
regulation of transport GO:0051049 181 0.030
cell junction organization GO:0034330 57 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.029
negative regulation of gene expression GO:0010629 387 0.029
actin cytoskeleton organization GO:0030036 206 0.029
inter male aggressive behavior GO:0002121 60 0.029
neuromuscular junction development GO:0007528 149 0.028
lipid localization GO:0010876 54 0.028
ribonucleotide metabolic process GO:0009259 145 0.028
gland development GO:0048732 191 0.028
limb development GO:0060173 1 0.027
regulation of phosphorus metabolic process GO:0051174 210 0.027
small molecule metabolic process GO:0044281 305 0.026
heart morphogenesis GO:0003007 32 0.026
response to abiotic stimulus GO:0009628 341 0.026
wnt signaling pathway GO:0016055 98 0.026
pigment metabolic process GO:0042440 84 0.026
cellular protein localization GO:0034613 160 0.026
cellular response to abiotic stimulus GO:0071214 58 0.026
axon ensheathment GO:0008366 10 0.026
imaginal disc growth GO:0007446 37 0.026
regulation of cellular response to stress GO:0080135 89 0.026
limb morphogenesis GO:0035108 1 0.025
protein localization to organelle GO:0033365 82 0.025
response to nutrient levels GO:0031667 114 0.025
locomotory behavior GO:0007626 176 0.025
negative regulation of synapse assembly GO:0051964 39 0.024
positive regulation of molecular function GO:0044093 136 0.024
regulation of protein localization GO:0032880 76 0.024
eye development GO:0001654 323 0.024
histolysis GO:0007559 102 0.024
protein localization to nucleus GO:0034504 55 0.024
meiotic nuclear division GO:0007126 151 0.024
purine containing compound metabolic process GO:0072521 155 0.023
peripheral nervous system development GO:0007422 52 0.023
protein modification process GO:0036211 438 0.023
apoptotic process GO:0006915 159 0.023
regulation of cell development GO:0060284 215 0.023
notch signaling pathway GO:0007219 120 0.022
developmental growth involved in morphogenesis GO:0060560 65 0.022
response to bacterium GO:0009617 198 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
regulation of molecular function GO:0065009 217 0.022
cellular response to radiation GO:0071478 52 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.021
cellular protein modification process GO:0006464 438 0.021
central nervous system development GO:0007417 201 0.021
single organism carbohydrate metabolic process GO:0044723 72 0.021
response to trehalose GO:0010353 3 0.020
meiotic chromosome segregation GO:0045132 59 0.020
regulation of multi organism process GO:0043900 131 0.020
axis specification GO:0009798 167 0.020
oxoacid metabolic process GO:0043436 103 0.020
cell adhesion GO:0007155 136 0.020
regulation of retinal cell programmed cell death GO:0046668 18 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
response to nitrogen compound GO:1901698 90 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.019
biological adhesion GO:0022610 138 0.019
positive regulation of developmental process GO:0051094 143 0.019
regulation of neuron projection development GO:0010975 69 0.019
branching involved in open tracheal system development GO:0060446 45 0.019
regulation of response to external stimulus GO:0032101 115 0.019
cellular catabolic process GO:0044248 372 0.019
positive regulation of intracellular signal transduction GO:1902533 116 0.019
regulation of hormone levels GO:0010817 40 0.019
regulation of cell growth GO:0001558 43 0.019
response to endogenous stimulus GO:0009719 119 0.019
positive regulation of immune effector process GO:0002699 28 0.019
programmed cell death GO:0012501 257 0.019
salivary gland histolysis GO:0035070 88 0.019
multi organism reproductive behavior GO:0044705 121 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
female meiotic division GO:0007143 70 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.018
response to oxygen containing compound GO:1901700 200 0.018
response to organic substance GO:0010033 284 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
neurological system process GO:0050877 358 0.018
sensory organ morphogenesis GO:0090596 260 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
response to alkaloid GO:0043279 26 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
single organism cellular localization GO:1902580 180 0.018
imaginal disc derived wing hair organization GO:0035317 45 0.017
nephron tubule morphogenesis GO:0072078 3 0.017
tube development GO:0035295 244 0.017
regulation of epithelial cell differentiation GO:0030856 4 0.017
nucleoside phosphate biosynthetic process GO:1901293 34 0.017
epithelial cell development GO:0002064 274 0.017
organelle fission GO:0048285 340 0.017
embryonic organ development GO:0048568 50 0.017
ensheathment of neurons GO:0007272 10 0.017
regulation of proteolysis GO:0030162 87 0.017
regulation of programmed cell death GO:0043067 152 0.016
immune response regulating signaling pathway GO:0002764 2 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
female meiosis chromosome segregation GO:0016321 33 0.016
nephron epithelium development GO:0072009 3 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
regulation of notch signaling pathway GO:0008593 100 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
meiotic cell cycle process GO:1903046 132 0.016
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.016
regulation of synapse organization GO:0050807 110 0.016
maintenance of location GO:0051235 73 0.016
regulation of cell death GO:0010941 173 0.015
establishment of protein localization GO:0045184 163 0.015
protein targeting to nucleus GO:0044744 51 0.015
glial cell differentiation GO:0010001 35 0.015
retinal cell programmed cell death GO:0046666 25 0.015
single organismal cell cell adhesion GO:0016337 45 0.015
regulation of neuron differentiation GO:0045664 103 0.015
cell cell junction organization GO:0045216 55 0.015
extrinsic apoptotic signaling pathway GO:0097191 1 0.015
axon ensheathment in central nervous system GO:0032291 3 0.015
mitotic sister chromatid segregation GO:0000070 87 0.015
regulation of neurogenesis GO:0050767 158 0.014
protein import GO:0017038 55 0.014
autophagy GO:0006914 108 0.014
sensory perception of chemical stimulus GO:0007606 116 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.014
cellular amine metabolic process GO:0044106 12 0.014
positive regulation of immune response GO:0050778 63 0.014
negative regulation of neurogenesis GO:0050768 53 0.014
body morphogenesis GO:0010171 2 0.014
response to organic cyclic compound GO:0014070 89 0.014
organophosphate metabolic process GO:0019637 195 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
embryonic morphogenesis GO:0048598 206 0.013
sister chromatid segregation GO:0000819 92 0.013
regulation of embryonic development GO:0045995 68 0.013
cell growth GO:0016049 108 0.013
oocyte construction GO:0007308 112 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
cortical cytoskeleton organization GO:0030865 29 0.013
establishment of tissue polarity GO:0007164 87 0.013
regulation of growth GO:0040008 233 0.013
regulation of developmental growth GO:0048638 174 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
regulation of response to stress GO:0080134 200 0.013
regulation of catabolic process GO:0009894 170 0.012
regulation of nucleotide metabolic process GO:0006140 62 0.012
response to organonitrogen compound GO:0010243 75 0.012
response to carbon dioxide GO:0010037 4 0.012
autophagic cell death GO:0048102 83 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
phenol containing compound metabolic process GO:0018958 57 0.012
regulation of protein transport GO:0051223 57 0.011
regulation of camp metabolic process GO:0030814 12 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
apical constriction involved in gastrulation GO:0003384 7 0.011
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.011
neuromuscular process GO:0050905 21 0.011
asymmetric cell division GO:0008356 37 0.011
protein processing GO:0016485 68 0.011
septate junction assembly GO:0019991 26 0.011
negative regulation of neural precursor cell proliferation GO:2000178 27 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
hemocyte differentiation GO:0042386 38 0.011
oocyte axis specification GO:0007309 108 0.011
response to temperature stimulus GO:0009266 106 0.011
ribonucleotide biosynthetic process GO:0009260 28 0.011
muscle structure development GO:0061061 224 0.011
spinal cord development GO:0021510 1 0.011
developmental maturation GO:0021700 172 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.011
brain morphogenesis GO:0048854 16 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
regulation of protein localization to nucleus GO:1900180 29 0.011
regulation of synapse assembly GO:0051963 94 0.011
cellular response to endogenous stimulus GO:0071495 80 0.011
regulation of lyase activity GO:0051339 14 0.010
digestive tract morphogenesis GO:0048546 127 0.010
organic substance catabolic process GO:1901575 308 0.010
regulation of cell differentiation GO:0045595 302 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
male gamete generation GO:0048232 201 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.010

smi35A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.051
disease of cellular proliferation DOID:14566 0 0.051
organ system cancer DOID:0050686 0 0.051
disease of anatomical entity DOID:7 0 0.012