Drosophila melanogaster

132 known processes

Bruce (Dmel_CG6303)

CG6303 gene product from transcript CG6303-RA

(Aliases: bruce,dBRUCE,CG6303,dbruce,Dmel\CG6303,dBruce)

Bruce biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell development GO:0060284 215 0.259
dendrite morphogenesis GO:0048813 199 0.175
regulation of nervous system development GO:0051960 248 0.150
positive regulation of developmental process GO:0051094 143 0.134
regulation of neurogenesis GO:0050767 158 0.102
response to biotic stimulus GO:0009607 294 0.090
mitotic nuclear division GO:0007067 213 0.084
defense response GO:0006952 300 0.076
regulation of microtubule cytoskeleton organization GO:0070507 41 0.072
regulation of mitotic cell cycle GO:0007346 190 0.070
regulation of multicellular organismal development GO:2000026 414 0.069
regulation of response to stress GO:0080134 200 0.063
dendrite development GO:0016358 204 0.062
developmental maturation GO:0021700 172 0.061
regulation of neuron differentiation GO:0045664 103 0.060
organelle localization GO:0051640 148 0.056
compound eye development GO:0048749 307 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.053
small molecule metabolic process GO:0044281 305 0.053
rrna processing GO:0006364 3 0.052
purine ribonucleoside metabolic process GO:0046128 127 0.052
female germ line cyst formation GO:0048135 42 0.051
intracellular signal transduction GO:0035556 300 0.049
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.045
vesicle mediated transport GO:0016192 381 0.044
cell cycle phase transition GO:0044770 140 0.044
regulation of cell cycle phase transition GO:1901987 130 0.043
body morphogenesis GO:0010171 2 0.043
negative regulation of cytoskeleton organization GO:0051494 30 0.042
cellular protein modification process GO:0006464 438 0.042
single organism cellular localization GO:1902580 180 0.042
proteolysis GO:0006508 192 0.040
positive regulation of cellular component organization GO:0051130 156 0.039
single organism intracellular transport GO:1902582 207 0.039
organic substance catabolic process GO:1901575 308 0.039
cellularization GO:0007349 90 0.038
regulation of cellular amine metabolic process GO:0033238 3 0.038
death GO:0016265 284 0.038
regulation of cellular amino acid metabolic process GO:0006521 0 0.037
negative regulation of gene expression GO:0010629 387 0.036
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.036
response to external biotic stimulus GO:0043207 293 0.036
cell proliferation GO:0008283 299 0.035
positive regulation of cellular protein metabolic process GO:0032270 118 0.034
protein localization GO:0008104 284 0.034
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.034
mitotic cell cycle phase transition GO:0044772 138 0.033
positive regulation of signal transduction GO:0009967 223 0.033
negative regulation of cellular metabolic process GO:0031324 382 0.033
regulation of dendrite morphogenesis GO:0048814 28 0.032
regulation of cell cycle process GO:0010564 181 0.032
appendage morphogenesis GO:0035107 397 0.032
protein modification process GO:0036211 438 0.032
cellular macromolecule localization GO:0070727 220 0.031
nucleobase containing compound catabolic process GO:0034655 165 0.031
intracellular ph reduction GO:0051452 7 0.030
regulation of neuron projection development GO:0010975 69 0.030
organic substance transport GO:0071702 257 0.030
negative regulation of rna biosynthetic process GO:1902679 240 0.029
aromatic compound catabolic process GO:0019439 166 0.029
rna processing GO:0006396 147 0.029
germarium derived female germ line cyst formation GO:0030727 42 0.029
compound eye morphogenesis GO:0001745 249 0.029
ncrna metabolic process GO:0034660 43 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
defense response to bacterium GO:0042742 178 0.029
defense response to other organism GO:0098542 225 0.028
ribonucleoside catabolic process GO:0042454 112 0.028
negative regulation of organelle organization GO:0010639 56 0.028
regulation of small gtpase mediated signal transduction GO:0051056 93 0.028
phosphorylation GO:0016310 294 0.028
response to other organism GO:0051707 293 0.028
cell maturation GO:0048469 144 0.027
carbohydrate derivative catabolic process GO:1901136 118 0.027
positive regulation of protein metabolic process GO:0051247 128 0.027
immune system process GO:0002376 347 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
heterocycle catabolic process GO:0046700 166 0.027
ribonucleoside triphosphate catabolic process GO:0009203 108 0.027
cellular response to dna damage stimulus GO:0006974 223 0.026
lateral inhibition GO:0046331 206 0.026
regulation of notch signaling pathway GO:0008593 100 0.026
olfactory learning GO:0008355 56 0.025
imaginal disc derived appendage morphogenesis GO:0035114 395 0.025
establishment of localization in cell GO:0051649 402 0.025
regulation of hydrolase activity GO:0051336 97 0.025
cellular protein catabolic process GO:0044257 83 0.025
positive regulation of nervous system development GO:0051962 69 0.025
dna metabolic process GO:0006259 227 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
translation GO:0006412 69 0.024
membrane organization GO:0061024 112 0.024
positive regulation of hydrolase activity GO:0051345 78 0.024
eye morphogenesis GO:0048592 260 0.024
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.024
regulation of gene expression epigenetic GO:0040029 128 0.024
regulation of cell proliferation GO:0042127 163 0.024
organonitrogen compound metabolic process GO:1901564 318 0.023
ion homeostasis GO:0050801 55 0.023
regulation of cell differentiation GO:0045595 302 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
programmed cell death GO:0012501 257 0.023
ribonucleoprotein complex subunit organization GO:0071826 28 0.022
regulation of molecular function GO:0065009 217 0.022
adult behavior GO:0030534 137 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.022
golgi localization GO:0051645 2 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.022
post embryonic appendage morphogenesis GO:0035120 385 0.022
positive regulation of organelle organization GO:0010638 65 0.022
nucleoside phosphate metabolic process GO:0006753 162 0.022
ribonucleoprotein complex biogenesis GO:0022613 31 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
single organism membrane organization GO:0044802 93 0.021
ribonucleoside triphosphate metabolic process GO:0009199 119 0.021
eye development GO:0001654 323 0.021
organophosphate catabolic process GO:0046434 112 0.021
positive regulation of biosynthetic process GO:0009891 316 0.021
cellular catabolic process GO:0044248 372 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.021
negative regulation of cell cycle process GO:0010948 109 0.021
purine containing compound catabolic process GO:0072523 112 0.021
regulation of catabolic process GO:0009894 170 0.020
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.020
modification dependent macromolecule catabolic process GO:0043632 79 0.020
sister chromatid segregation GO:0000819 92 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
establishment of protein localization GO:0045184 163 0.019
peptidyl amino acid modification GO:0018193 105 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
regulation of cellular component size GO:0032535 98 0.019
negative regulation of cellular component organization GO:0051129 108 0.019
germ line cyst formation GO:0048134 44 0.019
purine nucleoside triphosphate metabolic process GO:0009144 119 0.019
germarium derived egg chamber formation GO:0007293 101 0.019
regulation of rna splicing GO:0043484 69 0.019
rna localization GO:0006403 115 0.019
single organism catabolic process GO:0044712 228 0.019
posttranscriptional regulation of gene expression GO:0010608 145 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
protein complex biogenesis GO:0070271 201 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
nucleoside catabolic process GO:0009164 112 0.018
protein transport GO:0015031 155 0.018
cellular amine metabolic process GO:0044106 12 0.018
cellular amide metabolic process GO:0043603 80 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
g protein coupled receptor signaling pathway GO:0007186 136 0.018
macromolecular complex assembly GO:0065003 256 0.018
positive regulation of cell development GO:0010720 61 0.018
purine nucleoside metabolic process GO:0042278 127 0.017
regulation of immune system process GO:0002682 176 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
organophosphate metabolic process GO:0019637 195 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
central nervous system development GO:0007417 201 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
regulation of mrna splicing via spliceosome GO:0048024 64 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
endosomal transport GO:0016197 44 0.017
regulation of cellular catabolic process GO:0031329 157 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
positive regulation of catabolic process GO:0009896 105 0.016
negative regulation of neurogenesis GO:0050768 53 0.016
protein modification by small protein removal GO:0070646 28 0.016
regulation of cell size GO:0008361 63 0.016
negative regulation of mitotic cell cycle GO:0045930 109 0.016
intracellular transport GO:0046907 228 0.016
response to abiotic stimulus GO:0009628 341 0.016
regulation of anatomical structure size GO:0090066 163 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
erbb signaling pathway GO:0038127 58 0.016
negative regulation of cell cycle phase transition GO:1901988 103 0.015
intracellular protein transport GO:0006886 104 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
regulation of cell cycle GO:0051726 291 0.015
cytoplasmic transport GO:0016482 130 0.015
response to bacterium GO:0009617 198 0.015
macromolecule catabolic process GO:0009057 161 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
purine containing compound metabolic process GO:0072521 155 0.015
positive regulation of cell communication GO:0010647 250 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
regulation of catalytic activity GO:0050790 185 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
regulation of dendrite development GO:0050773 37 0.014
endomembrane system organization GO:0010256 119 0.014
single organism behavior GO:0044708 391 0.014
protein processing GO:0016485 68 0.014
maternal determination of anterior posterior axis embryo GO:0008358 74 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
mitotic dna integrity checkpoint GO:0044774 75 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
nuclear division GO:0000280 332 0.014
gliogenesis GO:0042063 80 0.014
amine metabolic process GO:0009308 12 0.014
forebrain development GO:0030900 2 0.014
rna splicing GO:0008380 83 0.014
cellular protein complex disassembly GO:0043624 35 0.013
posttranscriptional gene silencing GO:0016441 46 0.013
cell growth GO:0016049 108 0.013
nucleotide metabolic process GO:0009117 161 0.013
regulation of protein metabolic process GO:0051246 256 0.013
cell cycle g1 s phase transition GO:0044843 31 0.013
protein maturation GO:0051604 71 0.013
brain development GO:0007420 120 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
chromatin modification GO:0016568 147 0.013
chromatin organization GO:0006325 207 0.013
telencephalon development GO:0021537 2 0.013
protein acylation GO:0043543 42 0.012
exocrine system development GO:0035272 162 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
adult locomotory behavior GO:0008344 76 0.012
notch signaling pathway GO:0007219 120 0.012
antimicrobial humoral response GO:0019730 99 0.012
spermatogenesis GO:0007283 200 0.012
regulation of multi organism process GO:0043900 131 0.012
protein complex assembly GO:0006461 200 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
nucleus organization GO:0006997 45 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
epidermal growth factor receptor signaling pathway GO:0007173 58 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.012
cytokinesis GO:0000910 90 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
mrna metabolic process GO:0016071 124 0.012
regulation of defense response GO:0031347 102 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
membrane budding GO:0006900 4 0.011
salivary gland development GO:0007431 162 0.011
humoral immune response GO:0006959 117 0.011
morphogenesis of follicular epithelium GO:0016333 36 0.011
regulation of cell death GO:0010941 173 0.011
regulation of cell projection organization GO:0031344 92 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
mitotic cell cycle checkpoint GO:0007093 88 0.011
negative regulation of cell development GO:0010721 62 0.011
protein depolymerization GO:0051261 31 0.011
innate immune response GO:0045087 144 0.011
positive regulation of gtpase activity GO:0043547 43 0.011
gland morphogenesis GO:0022612 145 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
nucleoside metabolic process GO:0009116 127 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
regulation of cellular response to stress GO:0080135 89 0.011
regulation of erbb signaling pathway GO:1901184 42 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
mitotic chromosome condensation GO:0007076 22 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
spinal cord development GO:0021510 1 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
peptide metabolic process GO:0006518 80 0.010
protein polymerization GO:0051258 42 0.010
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.010
dna packaging GO:0006323 91 0.010
regulation of proteolysis GO:0030162 87 0.010
oocyte axis specification GO:0007309 108 0.010
mapk cascade GO:0000165 107 0.010
positive regulation of molecular function GO:0044093 136 0.010
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
regulation of response to biotic stimulus GO:0002831 63 0.010
gene silencing GO:0016458 138 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
negative regulation of developmental process GO:0051093 201 0.010

Bruce disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.012
central nervous system disease DOID:331 0 0.010
neurodegenerative disease DOID:1289 0 0.010