Drosophila melanogaster

57 known processes

lap (Dmel_CG2520)

like-AP180

(Aliases: BcDNA:GM10787,l(3)neo34,Lap,dAP-3,EP(3)3060,sig,AP180,Dmel\CG2520,CG2520,lap/AP180,LAP,EP3060)

lap biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 288 1.000
synaptic vesicle recycling GO:0036465 28 0.999
establishment of synaptic vesicle localization GO:0097480 50 0.999
establishment of vesicle localization GO:0051650 51 0.996
synaptic vesicle transport GO:0048489 50 0.987
synaptic vesicle localization GO:0097479 53 0.985
vesicle localization GO:0051648 55 0.985
neuron neuron synaptic transmission GO:0007270 14 0.981
synaptic vesicle endocytosis GO:0048488 28 0.979
synaptic vesicle exocytosis GO:0016079 16 0.979
organelle localization GO:0051640 148 0.967
response to radiation GO:0009314 155 0.920
axonogenesis GO:0007409 290 0.892
Mouse
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.748
establishment of organelle localization GO:0051656 122 0.717
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.550
neuromuscular synaptic transmission GO:0007274 67 0.548
endocytosis GO:0006897 310 0.544
regulation of response to external stimulus GO:0032101 115 0.521
axon development GO:0061564 297 0.510
Mouse
response to abiotic stimulus GO:0009628 341 0.471
developmental growth GO:0048589 280 0.441
cellular macromolecular complex assembly GO:0034622 153 0.416
Human Mouse
regulation of necrotic cell death GO:0010939 1 0.396
Worm
reproductive behavior GO:0019098 122 0.392
chemotaxis GO:0006935 249 0.391
regulation of synapse structure and activity GO:0050803 128 0.375
maintenance of presynaptic active zone structure GO:0048790 8 0.341
multi multicellular organism process GO:0044706 123 0.338
taxis GO:0042330 304 0.329
regulation of endocytosis GO:0030100 37 0.313
single organism behavior GO:0044708 391 0.312
synaptic vesicle priming GO:0016082 1 0.305
positive regulation of signaling GO:0023056 243 0.295
establishment of localization in cell GO:0051649 402 0.288
synapse organization GO:0050808 196 0.265
feeding behavior GO:0007631 50 0.263
muscle structure development GO:0061061 224 0.259
negative regulation of cellular component organization GO:0051129 108 0.259
Human
negative regulation of signaling GO:0023057 219 0.256
regulation of receptor mediated endocytosis GO:0048259 9 0.251
neurotransmitter secretion GO:0007269 35 0.248
positive regulation of neurotransmitter secretion GO:0001956 2 0.234
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.226
regulation of synapse organization GO:0050807 110 0.224
tissue morphogenesis GO:0048729 297 0.222
mating GO:0007618 120 0.203
vesicle organization GO:0016050 44 0.191
Human Mouse
forebrain development GO:0030900 2 0.190
regulation of glutamate receptor signaling pathway GO:1900449 1 0.190
localization of cell GO:0051674 257 0.189
deactivation of rhodopsin mediated signaling GO:0016059 17 0.179
regulation of transport GO:0051049 181 0.177
cation transport GO:0006812 110 0.174
Human
regulation of terminal button organization GO:2000331 11 0.172
single organism intracellular transport GO:1902582 207 0.169
Human
vesicle mediated transport GO:0016192 381 0.169
growth GO:0040007 359 0.167
negative regulation of synapse assembly GO:0051964 39 0.163
negative regulation of response to stimulus GO:0048585 258 0.155
organelle fusion GO:0048284 46 0.155
regulation of synaptic transmission GO:0050804 69 0.151
regulation of localization GO:0032879 275 0.149
axon guidance GO:0007411 233 0.149
response to light stimulus GO:0009416 124 0.148
regulation of synapse assembly GO:0051963 94 0.145
signal transduction by phosphorylation GO:0023014 107 0.142
developmental growth involved in morphogenesis GO:0060560 65 0.138
energy taxis GO:0009453 21 0.135
multicellular organismal reproductive behavior GO:0033057 110 0.133
regulation of cellular protein metabolic process GO:0032268 243 0.133
Mouse
anterograde synaptic vesicle transport GO:0048490 3 0.130
positive regulation of multicellular organism growth GO:0040018 21 0.130
positive regulation of cell development GO:0010720 61 0.126
signal release GO:0023061 49 0.125
cellular protein complex assembly GO:0043623 71 0.123
Human Mouse
positive regulation of cell death GO:0010942 69 0.121
Human Worm
negative regulation of developmental growth GO:0048640 64 0.121
regulation of developmental growth GO:0048638 174 0.121
neuromuscular junction development GO:0007528 149 0.121
cell proliferation GO:0008283 299 0.120
Human
regulation of nervous system development GO:0051960 248 0.119
cognition GO:0050890 141 0.118
body morphogenesis GO:0010171 2 0.115
phototaxis GO:0042331 21 0.114
organic substance catabolic process GO:1901575 308 0.113
regulation of multicellular organismal development GO:2000026 414 0.111
cellular catabolic process GO:0044248 372 0.107
microtubule based transport GO:0010970 42 0.106
single organism membrane organization GO:0044802 93 0.100
negative regulation of nervous system development GO:0051961 92 0.096
membrane organization GO:0061024 112 0.094
Human
regulation of behavior GO:0050795 75 0.093
nuclear division GO:0000280 332 0.093
regulation of locomotion GO:0040012 42 0.090
compound eye development GO:0048749 307 0.090
cellular monovalent inorganic cation homeostasis GO:0030004 7 0.089
sensory perception of chemical stimulus GO:0007606 116 0.089
response to organic substance GO:0010033 284 0.087
positive regulation of exocytosis GO:0045921 4 0.083
negative regulation of growth GO:0045926 84 0.083
intracellular transport GO:0046907 228 0.082
Human
macromolecular complex assembly GO:0065003 256 0.081
Human Mouse
locomotory behavior GO:0007626 176 0.079
neuron projection guidance GO:0097485 241 0.078
regulation of phosphate metabolic process GO:0019220 210 0.078
negative regulation of signal transduction GO:0009968 206 0.078
negative regulation of cell communication GO:0010648 223 0.078
multi organism reproductive behavior GO:0044705 121 0.077
positive regulation of transport GO:0051050 92 0.076
dopamine metabolic process GO:0042417 7 0.075
mapk cascade GO:0000165 107 0.075
catabolic process GO:0009056 409 0.073
regulation of vesicle mediated transport GO:0060627 59 0.072
multicellular organism growth GO:0035264 46 0.072
regulation of hormone levels GO:0010817 40 0.071
purine nucleoside triphosphate metabolic process GO:0009144 119 0.070
regulation of cell cycle GO:0051726 291 0.070
positive regulation of axon guidance GO:1902669 1 0.068
ion transport GO:0006811 145 0.068
Human
cell death GO:0008219 279 0.067
Human Worm
adult locomotory behavior GO:0008344 76 0.067
regulation of cellular component biogenesis GO:0044087 201 0.066
gtp catabolic process GO:0006184 72 0.065
positive regulation of cell communication GO:0010647 250 0.064
regulation of response to stress GO:0080134 200 0.063
regulation of catabolic process GO:0009894 170 0.063
cellular response to light stimulus GO:0071482 37 0.062
regulation of phosphorylation GO:0042325 147 0.062
regulation of growth GO:0040008 233 0.062
embryonic hindgut morphogenesis GO:0048619 48 0.061
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.061
membrane tubulation GO:0097320 4 0.061
positive regulation of secretion GO:0051047 22 0.060
regulation of secretion GO:0051046 44 0.060
sensory perception GO:0007600 196 0.059
posttranscriptional regulation of gene expression GO:0010608 145 0.059
nucleoside phosphate catabolic process GO:1901292 110 0.059
single organism membrane fusion GO:0044801 42 0.059
hindgut development GO:0061525 58 0.059
defense response GO:0006952 300 0.059
small molecule metabolic process GO:0044281 305 0.058
regulation of secretion by cell GO:1903530 39 0.058
regulation of phosphorus metabolic process GO:0051174 210 0.058
segmentation GO:0035282 207 0.057
regulation of neurogenesis GO:0050767 158 0.056
phosphorylation GO:0016310 294 0.055
ameboidal type cell migration GO:0001667 151 0.055
regulation of cell differentiation GO:0045595 302 0.054
hindbrain development GO:0030902 2 0.053
embryo development ending in birth or egg hatching GO:0009792 152 0.053
Worm
positive regulation of developmental process GO:0051094 143 0.052
exocytosis GO:0006887 28 0.052
regulation of neurotransmitter secretion GO:0046928 14 0.052
protein ubiquitination GO:0016567 70 0.052
protein modification process GO:0036211 438 0.051
enzyme linked receptor protein signaling pathway GO:0007167 179 0.051
nucleoside catabolic process GO:0009164 112 0.050
membrane fusion GO:0061025 42 0.050
single organism cellular localization GO:1902580 180 0.049
positive regulation of nucleotide catabolic process GO:0030813 46 0.048
cell growth GO:0016049 108 0.048
regulation of epithelial cell proliferation GO:0050678 4 0.048
carbohydrate derivative metabolic process GO:1901135 217 0.048
positive regulation of catabolic process GO:0009896 105 0.048
sensory perception of pain GO:0019233 4 0.046
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.046
anatomical structure homeostasis GO:0060249 97 0.046
protein phosphorylation GO:0006468 169 0.045
eye morphogenesis GO:0048592 260 0.045
regulation of protein kinase a signaling GO:0010738 2 0.045
peptidyl threonine phosphorylation GO:0018107 2 0.044
ion transmembrane transport GO:0034220 122 0.044
embryonic morphogenesis GO:0048598 206 0.044
cell motility GO:0048870 251 0.044
renal tubule morphogenesis GO:0061333 44 0.043
positive regulation of cellular component organization GO:0051130 156 0.043
organelle assembly GO:0070925 198 0.043
epithelial cell migration GO:0010631 148 0.042
actin filament based process GO:0030029 220 0.042
endomembrane system organization GO:0010256 119 0.041
protein transport GO:0015031 155 0.041
regulation of synaptic vesicle exocytosis GO:2000300 3 0.041
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.041
positive regulation of kinase activity GO:0033674 25 0.040
cellular protein modification process GO:0006464 438 0.040
negative regulation of cellular catabolic process GO:0031330 34 0.039
organic substance transport GO:0071702 257 0.039
regulation of gtp catabolic process GO:0033124 44 0.038
regionalization GO:0003002 416 0.038
regulation of protein catabolic process GO:0042176 55 0.038
g protein coupled receptor signaling pathway GO:0007186 136 0.038
axis specification GO:0009798 167 0.038
macromolecule catabolic process GO:0009057 161 0.038
regulation of protein localization GO:0032880 76 0.038
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.038
positive regulation of catalytic activity GO:0043085 118 0.037
Mouse
lipid localization GO:0010876 54 0.037
nucleoside triphosphate metabolic process GO:0009141 120 0.037
epithelial cell differentiation GO:0030855 322 0.037
regulation of cellular component size GO:0032535 98 0.036
positive regulation of cellular protein metabolic process GO:0032270 118 0.035
Mouse
embryonic development via the syncytial blastoderm GO:0001700 148 0.035
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.035
regulation of cell development GO:0060284 215 0.035
male gamete generation GO:0048232 201 0.034
mitotic cell cycle embryonic GO:0045448 38 0.034
apical constriction GO:0003383 18 0.034
death GO:0016265 284 0.034
Human Worm
cellular response to nutrient levels GO:0031669 62 0.034
cellular response to carbon dioxide GO:0071244 2 0.034
regulation of neurotransmitter transport GO:0051588 14 0.033
glycosyl compound catabolic process GO:1901658 112 0.033
organonitrogen compound catabolic process GO:1901565 128 0.033
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.033
pigment metabolic process GO:0042440 84 0.033
necrotic cell death GO:0070265 1 0.033
Worm
compound eye photoreceptor development GO:0042051 78 0.033
developmental cell growth GO:0048588 52 0.033
clathrin mediated endocytosis GO:0072583 7 0.032
neurotransmitter transport GO:0006836 37 0.032
membrane budding GO:0006900 4 0.032
Human
regulation of epithelial cell migration GO:0010632 12 0.032
negative regulation of multicellular organismal process GO:0051241 142 0.032
jnk cascade GO:0007254 50 0.032
vesicle fusion GO:0006906 19 0.031
response to acid chemical GO:0001101 25 0.031
positive regulation of secretion by cell GO:1903532 20 0.031
positive regulation of protein transport GO:0051222 37 0.031
positive regulation of axonogenesis GO:0050772 2 0.031
multi organism behavior GO:0051705 175 0.031
aging GO:0007568 143 0.031
regulation of cellular localization GO:0060341 136 0.030
establishment or maintenance of cell polarity GO:0007163 167 0.030
detection of light stimulus GO:0009583 58 0.030
central nervous system development GO:0007417 201 0.030
positive regulation of neurogenesis GO:0050769 41 0.030
regulation of establishment of protein localization GO:0070201 61 0.029
regulation of protein transport GO:0051223 57 0.029
head development GO:0060322 135 0.029
purine containing compound catabolic process GO:0072523 112 0.029
oviposition GO:0018991 19 0.029
compound eye morphogenesis GO:0001745 249 0.028
protein localization GO:0008104 284 0.028
Human
positive regulation of multicellular organismal process GO:0051240 143 0.028
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.028
phagocytosis GO:0006909 215 0.028
positive regulation of phosphate metabolic process GO:0045937 139 0.028
positive regulation of hydrolase activity GO:0051345 78 0.028
Mouse
dephosphorylation GO:0016311 51 0.028
tripartite regional subdivision GO:0007351 103 0.027
anterograde axon cargo transport GO:0008089 6 0.027
heterocycle catabolic process GO:0046700 166 0.027
regulation of membrane depolarization GO:0003254 1 0.027
cellular protein complex disassembly GO:0043624 35 0.027
regulation of receptor activity GO:0010469 10 0.027
muscle system process GO:0003012 21 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.026
single organism catabolic process GO:0044712 228 0.026
positive regulation of cell migration GO:0030335 2 0.026
regulation of neurotransmitter levels GO:0001505 38 0.026
single organismal cell cell adhesion GO:0016337 45 0.026
negative regulation of developmental process GO:0051093 201 0.026
positive regulation of transferase activity GO:0051347 26 0.025
telencephalon development GO:0021537 2 0.025
mitotic cytokinesis GO:0000281 50 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
ion homeostasis GO:0050801 55 0.025
Human
synapse assembly GO:0007416 143 0.025
regulation of axonogenesis GO:0050770 32 0.025
positive regulation of synaptic vesicle endocytosis GO:1900244 4 0.024
regulation of dendrite morphogenesis GO:0048814 28 0.024
cell migration GO:0016477 238 0.024
detection of stimulus GO:0051606 156 0.024
social behavior GO:0035176 4 0.024
tube morphogenesis GO:0035239 191 0.024
learning or memory GO:0007611 141 0.024
protein complex assembly GO:0006461 200 0.024
Human Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.024
Mouse
regulation of synaptic vesicle transport GO:1902803 10 0.023
regulation of cytoskeleton organization GO:0051493 89 0.023
peptidyl threonine modification GO:0018210 3 0.023
positive regulation of neurotransmitter transport GO:0051590 2 0.023
regulation of cell morphogenesis GO:0022604 163 0.023
regulation of short term neuronal synaptic plasticity GO:0048172 5 0.023
regulation of intracellular protein transport GO:0033157 46 0.023
anesthesia resistant memory GO:0007615 6 0.023
purine ribonucleotide metabolic process GO:0009150 145 0.023
cellular component disassembly GO:0022411 46 0.023
regulation of mapk cascade GO:0043408 92 0.023
synaptic growth at neuromuscular junction GO:0051124 119 0.022
secretion GO:0046903 109 0.022
regulation of cellular catabolic process GO:0031329 157 0.022
short term memory GO:0007614 19 0.022
cell recognition GO:0008037 102 0.022
positive regulation of nervous system development GO:0051962 69 0.022
neurological system process GO:0050877 358 0.022
establishment of mitochondrion localization GO:0051654 7 0.022
digestive tract morphogenesis GO:0048546 127 0.022
protein complex biogenesis GO:0070271 201 0.022
Human Mouse
ribonucleotide metabolic process GO:0009259 145 0.022
organic cyclic compound catabolic process GO:1901361 168 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.022
positive regulation of protein metabolic process GO:0051247 128 0.022
Human Mouse
translation GO:0006412 69 0.022
positive regulation of intracellular signal transduction GO:1902533 116 0.022
organonitrogen compound metabolic process GO:1901564 318 0.021
Human Mouse
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.021
homeostatic process GO:0042592 199 0.021
Human
positive regulation of nucleotide metabolic process GO:0045981 55 0.021
monovalent inorganic cation homeostasis GO:0055067 7 0.021
proteolysis GO:0006508 192 0.021
Human Mouse
muscle tissue morphogenesis GO:0060415 2 0.021
organic acid metabolic process GO:0006082 103 0.021
purine containing compound metabolic process GO:0072521 155 0.021
epithelial tube morphogenesis GO:0060562 88 0.021
immune effector process GO:0002252 98 0.021
regulation of cell cycle phase transition GO:1901987 130 0.020
purine ribonucleotide catabolic process GO:0009154 109 0.020
response to extracellular stimulus GO:0009991 116 0.020
purine nucleotide catabolic process GO:0006195 109 0.020
mating behavior GO:0007617 106 0.020
mushroom body development GO:0016319 70 0.020
positive regulation of rac gtpase activity GO:0032855 8 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
chromosome segregation GO:0007059 157 0.019
positive regulation of cellular component biogenesis GO:0044089 80 0.019
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
positive regulation of developmental growth GO:0048639 62 0.019
tissue migration GO:0090130 155 0.019
autophagic vacuole assembly GO:0000045 2 0.019
regulation of gene expression epigenetic GO:0040029 128 0.019
gene silencing by mirna GO:0035195 22 0.019
negative regulation of epithelial cell proliferation GO:0050680 4 0.018
negative regulation of phosphate metabolic process GO:0045936 45 0.018
negative regulation of catabolic process GO:0009895 36 0.018
conditioned taste aversion GO:0001661 3 0.018
regulation of cell death GO:0010941 173 0.018
Human Worm
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.018
response to wounding GO:0009611 94 0.018
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.018
cellular ketone metabolic process GO:0042180 24 0.018
erbb signaling pathway GO:0038127 58 0.018
developmental maturation GO:0021700 172 0.018
Mouse
morphogenesis of an epithelium GO:0002009 276 0.018
positive regulation of molecular function GO:0044093 136 0.018
Mouse
positive regulation of gtp catabolic process GO:0033126 43 0.018
organic hydroxy compound metabolic process GO:1901615 83 0.018
posttranscriptional gene silencing GO:0016441 46 0.018
spermatogenesis GO:0007283 200 0.018
positive regulation of jun kinase activity GO:0043507 4 0.018
positive regulation of nucleoside metabolic process GO:0045979 47 0.018
dopamine receptor signaling pathway GO:0007212 4 0.018
multicellular organismal aging GO:0010259 140 0.017
regulation of mitotic cell cycle phase transition GO:1901990 130 0.017
modification dependent protein catabolic process GO:0019941 78 0.017
eye development GO:0001654 323 0.017
sensory organ morphogenesis GO:0090596 260 0.017
positive regulation of cell motility GO:2000147 3 0.017
nitrogen compound transport GO:0071705 85 0.017
response to heat GO:0009408 63 0.017
intracellular protein transport GO:0006886 104 0.017
regulation of synaptic vesicle endocytosis GO:1900242 7 0.017
negative regulation of protein metabolic process GO:0051248 85 0.017
Mouse
regulation of hydrolase activity GO:0051336 97 0.017
Human Mouse
negative regulation of cell death GO:0060548 81 0.016
posttranscriptional gene silencing by rna GO:0035194 45 0.016
apical constriction involved in gastrulation GO:0003384 7 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
Human Mouse
positive regulation of mapk cascade GO:0043410 63 0.016
larval locomotory behavior GO:0008345 27 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
establishment of mitochondrion localization microtubule mediated GO:0034643 6 0.016
spindle organization GO:0007051 253 0.016
guanosine containing compound metabolic process GO:1901068 74 0.016
regulation of protein phosphorylation GO:0001932 64 0.016
cell adhesion GO:0007155 136 0.016
purine nucleoside catabolic process GO:0006152 112 0.016
cell fate determination GO:0001709 91 0.016
immune system process GO:0002376 347 0.015
Mouse
protein import into nucleus GO:0006606 51 0.015
positive regulation of sequestering of triglyceride GO:0010890 1 0.015
anterior posterior axis specification embryo GO:0008595 103 0.015
regulated secretory pathway GO:0045055 1 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
regulation of protein kinase activity GO:0045859 51 0.015
response to external biotic stimulus GO:0043207 293 0.015
regulation of cell projection organization GO:0031344 92 0.015
covalent chromatin modification GO:0016569 106 0.015
response to starvation GO:0042594 97 0.015
cortical cytoskeleton organization GO:0030865 29 0.015
positive regulation of synaptic transmission GO:0050806 15 0.015
extracellular structure organization GO:0043062 46 0.015
phenol containing compound metabolic process GO:0018958 57 0.015
terminal button organization GO:0072553 19 0.015
respiratory system development GO:0060541 213 0.015
mitotic nuclear division GO:0007067 213 0.015
defense response to other organism GO:0098542 225 0.015
amine metabolic process GO:0009308 12 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
positive regulation of receptor mediated endocytosis GO:0048260 7 0.014
organophosphate catabolic process GO:0046434 112 0.014
neuron projection extension GO:1990138 32 0.014
cytoplasmic transport GO:0016482 130 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
positive regulation of protein complex assembly GO:0031334 22 0.014
positive regulation of cell differentiation GO:0045597 64 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.014
stress activated protein kinase signaling cascade GO:0031098 55 0.014
leg disc development GO:0035218 92 0.014
asymmetric stem cell division GO:0098722 49 0.014
hindgut morphogenesis GO:0007442 58 0.014
regulation of jnk cascade GO:0046328 40 0.014
regulation of cellular protein catabolic process GO:1903362 44 0.014
tube development GO:0035295 244 0.014
ras protein signal transduction GO:0007265 88 0.014
renal tubule development GO:0061326 64 0.014
ovarian follicle cell development GO:0030707 248 0.014
positive regulation of signal transduction GO:0009967 223 0.014
centrosome organization GO:0051297 163 0.013
regulation of transmembrane transport GO:0034762 27 0.013
protein localization to synapse GO:0035418 1 0.013
regulation of purine nucleotide catabolic process GO:0033121 48 0.013
response to oxidative stress GO:0006979 86 0.013
notch signaling pathway GO:0007219 120 0.013
tissue homeostasis GO:0001894 36 0.013
establishment of planar polarity GO:0001736 87 0.013
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.013
gland development GO:0048732 191 0.013
response to oxygen containing compound GO:1901700 200 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.013
regulation of rhodopsin mediated signaling pathway GO:0022400 17 0.013
detection of visible light GO:0009584 38 0.013
axon extension GO:0048675 32 0.013
peptidyl amino acid modification GO:0018193 105 0.013
defense response to bacterium GO:0042742 178 0.013
retina morphogenesis in camera type eye GO:0060042 2 0.013
regulation of protein complex disassembly GO:0043244 29 0.013
protein processing GO:0016485 68 0.013
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.012
axon midline choice point recognition GO:0016199 26 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
asymmetric neuroblast division GO:0055059 33 0.012
pathway restricted smad protein phosphorylation GO:0060389 1 0.012
response to carbon dioxide GO:0010037 4 0.012
regulation of cell maturation GO:1903429 27 0.012
regulation of organelle organization GO:0033043 196 0.012
muscle contraction GO:0006936 13 0.012
germarium derived egg chamber formation GO:0007293 101 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
monocarboxylic acid transport GO:0015718 3 0.012
regulation of protein metabolic process GO:0051246 256 0.012
Human Mouse
regulation of protein deacetylation GO:0090311 2 0.012
biological adhesion GO:0022610 138 0.012
protein complex disassembly GO:0043241 36 0.012
cellular component maintenance GO:0043954 23 0.012
protein modification by small protein conjugation GO:0032446 79 0.011
immune response GO:0006955 246 0.011
response to biotic stimulus GO:0009607 294 0.011
sensory perception of mechanical stimulus GO:0050954 72 0.011
neuron death GO:0070997 27 0.011
Human
actin cytoskeleton organization GO:0030036 206 0.011
purine containing compound biosynthetic process GO:0072522 30 0.011
regulation of embryonic development GO:0045995 68 0.011
regulation of protein processing GO:0070613 32 0.011
Mouse
protein catabolic process GO:0030163 101 0.011
negative regulation of protein processing GO:0010955 31 0.011
Mouse
nuclear body organization GO:0030575 6 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
response to inorganic substance GO:0010035 44 0.011
gtp metabolic process GO:0046039 72 0.011
activation of jun kinase activity GO:0007257 3 0.011
regulation of cell proliferation GO:0042127 163 0.011
gene silencing by rna GO:0031047 57 0.011
potassium ion transport GO:0006813 20 0.011
cell fate specification GO:0001708 71 0.011
larval behavior GO:0030537 42 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010
Human
actin mediated cell contraction GO:0070252 21 0.010
chaeta development GO:0022416 97 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010

lap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.291
parkinson s disease DOID:14330 0 0.065
synucleinopathy DOID:0050890 0 0.065
central nervous system disease DOID:331 0 0.065
neurodegenerative disease DOID:1289 0 0.065
nervous system disease DOID:863 0 0.065
musculoskeletal system disease DOID:17 0 0.031
neuromuscular disease DOID:440 0 0.016
neuropathy DOID:870 0 0.016
kidney disease DOID:557 0 0.014
urinary system disease DOID:18 0 0.014
charcot marie tooth disease DOID:10595 0 0.011